Respiratory System Practice Quiz For Um/Fau

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1. Which of the following patients would you expect to have the worst mucociliary function?

Explanation

This one is probably debatable, as I gave every patient at least one condition that causes decreased mucociliary transport. I picked D as the correct answer because of the graph in Dr. Fischer's lecture that shows mucociliary transport lowest in smokers with bronchitis. Also, patient D has 3 strikes against him/her (age, bronchitis, smoking).

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About This Quiz
Respiratory System Practice Quiz For Um/Fau - Quiz

This test is a practice test designed for UM/FAU medical students getting ready for Respiratory test number two.

2. True or false:  A negative PPD test rules out TB in a patient with AIDS.

Explanation

Due to immunosuppression, PPD can have false negative in AIDS pts so it doesn't rule out TB

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3. Which statement is true regarding TB treatment regimens?

Explanation

A: Multi-drug resistant TB is becoming a significant problem
B: Minimum treatment time is 6 months
C: Cavitation indicates active infection, so poor prognosis
D: I am sure that many believe this, but I haven't seen any RCT's on this topic yet
E: These two drugs are the most important parts of TB treatment (assuming no resistance is likely)

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4. A 70 year old man with a 50 pack year history of smoking presents to the ED with a COPD exacerbation.  ABGs are:
pH: 7.24
PO2: 30
PCO2: 60
HCO3: 34

What is the acid base disturbance?

Explanation

High PCO2 and low pH means that it is a resp. acidosis. HCO3 is elevated as a normal compensatory response.

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5. Which of the following are physical defense systems of the lung?

Explanation

The correct answer is "Upper airway filtering, Cough and Sneeze reflexes, mucociliary escalator." These are physical defense systems of the lung that help to protect against foreign particles and pathogens. The upper airway filtering refers to the nose and throat filtering out larger particles before they reach the lungs. The cough and sneeze reflexes help to expel irritants and pathogens from the respiratory tract. The mucociliary escalator is a mechanism where tiny hair-like structures called cilia move mucus and trapped particles out of the lungs. These physical defense systems work together to prevent harmful substances from entering and causing damage to the lungs.

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6. Which of the following is seen in Chronic Lung Disease (aka Bronchopulmonary dysplasia)?

Explanation

Chronic Lung Disease, also known as Bronchopulmonary dysplasia, is a condition that primarily affects premature infants who require mechanical ventilation and oxygen therapy. It is characterized by lung inflammation, which can be caused by mechanical injury from the ventilator, oxygen toxicity due to prolonged exposure to high levels of oxygen, and increased susceptibility to infections and sepsis. Therefore, all of the options mentioned in the question - mechanical injury, oxygen toxicity, infection and sepsis, and inflammation - are seen in Chronic Lung Disease.

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7. What is the most common type of cancer in the head and neck?

Explanation

Squamous cell carcinoma is the most common type of cancer in the head and neck. It arises from the squamous cells that line the mucosal surfaces of the head and neck, such as the mouth, throat, and voice box. Risk factors for this type of cancer include tobacco and alcohol use, as well as infection with certain types of human papillomavirus (HPV). Squamous cell carcinoma can present with symptoms like a sore throat, difficulty swallowing, or a lump in the neck. Treatment options include surgery, radiation therapy, and chemotherapy.

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8. Why is it more difficult for the lungs to compensate for a metabolic alkalosis than a metabolic acidosis?

Explanation

The response to alkalosis is hypoventilation, which means that the lungs decrease the rate and depth of breathing. This leads to a decrease in the amount of oxygen in the blood, resulting in hypoxemia. In contrast, in a metabolic acidosis, the lungs can compensate by increasing the rate and depth of breathing to eliminate excess carbon dioxide and increase blood pH. Therefore, it is more difficult for the lungs to compensate for a metabolic alkalosis than a metabolic acidosis.

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9. A 20-year-old man presents to the emergency department with complaints of left-sided chest pain and shortness of breath. He states that these symptoms began suddenly 4 days ago while he was working at his computer. He initially thought that he may have strained a chest wall muscle but, since the pain and dyspnea had not resolved, he decided to seek medical attention. He has no significant past medical history but has smoked cigarettes since the age of 16 years. His older brother suffered a pneumothorax at the age of 23 years. The patient's vital signs are normal. He appears in mild discomfort. X-ray is shown below:
What physical exam findings would you expect to see in this patient?

Explanation

Pneumothorax would show hyperresonance to percussion and decreased tactile fremitus. Egophany, whispered pq, dullness to percussion, and increased tactile fremitus all indicate consolidation, not pneumothorax.

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10. What grade of pulmonary hypertension is this image?
 

Explanation

This slide shows the 'onion skin' appearance of grade 3 pulmonary HTN. The lumen is completely blocked but there is no fibrinoid necrosis.

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11. A 64 year old former politician is seen by his primary care physician for pain on urination, wheezing, dyspnea, and cough productive of brown sputum.  He admits to trying marijuana, but "didn't inhale." He is diagnosed with aspergilloma and chlamydia.  Given that aspergillus particles are about 3.5 microns in diameter, in which part of the airway is the aspergillus likely to be lodged?

Explanation

Alveolus is

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12. Which of these is not a phase of coughing?

Explanation

Coughing is a reflex action that helps to clear the airways of irritants or mucus. The phases of coughing involve different actions of the respiratory muscles. The expiratory phase refers to the forceful exhalation of air during a cough. The compressive phase refers to the compression of the airways to generate a strong cough. The inspiratory phase refers to the inhalation of air before the cough. However, the term "expressive" does not correspond to any specific phase of coughing. It does not describe any action or component of the coughing process.

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13. Which of the following is characteristic of an exudate?

Explanation

Light's criteria for an exudate are one or more of the following:
Pleural fluid protein/serum protein > 0.5
Pleural fluid LDH/serum LDH > 0.6
Pleural fluid LDH > 2/3 the upper limits of the normal serum LDH
Additional criteria include: Pleural fluid protein > 2.9 g/dL
Pleural fluid cholesterol > 45 mg/dL (does not by itself provide a definitive diagnosis of an exudate)

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14. What is the most common cause of bronchiolitis in children?

Explanation

Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in children. Bronchiolitis is an infection that affects the small airways in the lungs, causing inflammation and difficulty breathing. RSV is highly contagious and spreads through respiratory droplets. It is most common in infants and young children, especially during the winter months. RSV can cause symptoms such as coughing, wheezing, fever, and difficulty feeding. It is important to note that while other viruses like parainfluenza, rhinovirus, adenovirus, and coronavirus can also cause bronchiolitis, RSV is the most common culprit.

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15. Which of the following is/are true about Haemophilus influenza?

Explanation

A: polysaccharide capsule is main virulence factor, B: sputum commonly contaminated with H. flu, D: commonly seen in COPD

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16. Which of these is a disadvantage of pressure controlled ventilation?

Explanation

Pressure controlled ventilation is a mode of mechanical ventilation where the inspiratory pressure is set and the ventilator delivers a constant pressure during inspiration. While pressure controlled ventilation allows for control of inspiratory pressure level and I:E ratio, it has the disadvantage of being unable to directly control minute ventilation. Minute ventilation is the amount of air that is moved in and out of the lungs in one minute and is determined by both the tidal volume and the respiratory rate. In pressure controlled ventilation, the minute ventilation is indirectly controlled by adjusting the inspiratory time and respiratory rate, but it is not directly controlled like in volume controlled ventilation.

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17. Which of these patients would be indicated to receive mechanical ventilation?

Explanation

Indications for ventilation: RR>35, TV10mmHg, refractory hypoxemia

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18. A 34-year-old man with a history of sex with men presents with 3 weeks of worsening dyspnea associated with fevers and a non-productive cough. He is tachycardic, tachypneic and has a temperature of 100.5°F (38.1°C). His pulse oximetry is 86% on room air. He appears thin and in moderate respiratory distress. His lung examination is unremarkable.  Patient lives in Arkansas, and denies recent travel.  Chest x-ray shows bilateral symmetrical interstitial infiltrates.  LDH is measured at 250 IU/L.  A-a O2 gradient is elevated.  What is the diagnosis?

Explanation

Sarcoidosis presents similarly to PCP, but has systemic involvement including skin nodules, Coccidiomycosis is unlikely due to lack of exposure, MAC is uncommon in HIV patients and more often presents with extrapulmonary symptoms, S. pneumo is unlikely due to the slow onset and interstitial infiltrates.

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19. A:   

B:    


Which of these are suspicious for cancer?

Explanation

Irregular spiculated masses are highly suspicious for cancer.

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20. Which group of pulmonary hypertension is correctly matched with its definition?

Explanation

Correct matchings are as follows:
Group 1 PAH: Pulmonary Arterial Hypertension
Group 2 PH: Pulmonary hypertension with left heart disease
Group 3 PH: Pulmonary hypertension associated with lung diseases and/or hypoxemia
Group 4 PH: Pulmonary hypertension due to chronic thrombotic and/or embolic disease
Group 5 PH: Miscellaneous or caused by inflammation, obstruction, or extrinsic compression

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21. A patient in the ICU has a PaO2 of 100 and an FiO2 of 40%.  The patient also has a normal PA wedge pressure and bilateral infiltrates on x-ray.  Which most accurately describes the most appropriate diagnosis and treatment of this patient?

Explanation

If PaO2/FiO2 ratio is 200, it is ALI. This patient's ratio is 250, so it is ALI.

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22. Which of the following is not one of the common constitutional symptoms of reactivation TB?

Explanation

Headache is not one of the common constitutional symptoms of reactivation TB. Reactivation TB commonly presents with symptoms such as anorexia, fever, unintentional weight loss, and night sweats. While headaches can occur in some cases of TB, they are not considered one of the common constitutional symptoms.

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23. Which statement is true regarding patients with latent TB infections?

Explanation

Latent TB will test positive on PPD test, they are at increased risk of active TB, they are not contagious, and do not usually show symptoms.

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24. Which of the following pulmonary diseases is properly matched up with the CD4 count (cells/mm3) it is associated with in HIV patients?

Explanation

Sinusitis and bronchitis can occur at any CD4, CMV usually occurs at

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25.
The patient with the above angiogram has a BP of 80/60, and is determined to be hemodynamically unstable.  What treatment is indicated?

Explanation

The angiogram shows a PE, and since the patient is hemodynamically unstable, thrombolytics are indicated unless there is a contraindication in order to prevent cardiac arrest. Heparin does not help dissolve an already existing clot.

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26. A 50 year old male presents with productive cough, fever, and chills.  His respiratory rate is 32.  The medical student on duty orders a CBC and the results show a WBC count of 20,000.  CXR shows a lobar consolidation.  Blood cultures return positive for Streptococcus pneumoniae.  Which of the following is/are true about S. pneumoniae?

Explanation

A: rare, B: 20-50% positive, C: splits IgA, D: vaccine prevents 25 most common serotypes

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27. A 36-year-old woman presents with a 6-month history of gradually progressive dyspnea on exertion and fatigue. On physical exam, her vital signs are normal and she appears not to be in any distress. Her lungs are clear to auscultation. Her cardiac exam shows a prominent jugular V wave, an accentuated pulmonic component to the second heart sound (P2) and a high-pitched holosystolic murmur best heard at the left sternal border.  Which of the following statements is most likely to be true about the pathogenesis of her condition?

Explanation

This vignette is supposed to describe idiopathic pulmonary hypertension. Current thoughts on IPH indicate that there is some genetic predisposition but that a 'second hit' is needed, much like in cancer. IPH is also associated with low NO and prostacyclin levels, and high endothelin levels.

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28. A 3-month-old boy is referred by his pediatrician with intermittent inspiratory stridor and progressive feeding difficulties resulting in failure to thrive. The stridor has been present since he was 1 week old. His parents report that his noisy breathing is present more frequently and is particularly prominent when he is lying down, feeding, or crying. He has difficulty feeding and chokes frequently but has a normal cry. His mother reports that he feeds slowly and often has to stop several times during the feed to "gasp for breath." He has recently been diagnosed with GERD.  Flexible laryngoscopy reveals the following image:
What is the diagnosis?

Explanation

Laryngomalacia is a floppy airway during inspiration due to cartilage underdevelopment. It resolves on its own usually.

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29.
This sample was isolated from a 75 year old woman in the ICU who has been on mechanical ventilation for 1 month following a viral infection.  Which of the following would you, as an astute medical student, expect to see in this patient?

Explanation

Organism is Staph aureus.
A: sputum usually neg, blood usually pos, C: Cat and Coag positive, D: Typical presentation of Legionella, E: Typical of Mycoplasma

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30.
What are the predominant features of this EKG, taken from a patient with pulmonary hypertension?

Explanation

This EKG shows signs of RVH: Right axis deviation, p pulmonale, and R/S ratio of >1

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31.
Which of the following would increase the likelihood of the condition depicted above the most?

Explanation

This CT shows mesothelioma. Asbestos exposure is the major risk factor for this disease, but smoking in conjunction with exposure accelerates the disease process.

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32. For a patient with a pulmonary embolism, which is the most likely acid-base disturbance?

Explanation

In patients with PE, you see:
Impaired gas exchange (hypoxemia)
Increased pulmonary vascular resistance (vascular obstruction)
Alveolar hyperventilation (hypocarbia)
So…most likely ABG: alkalemic pH, low pO2, low pCO2 (respiratory alkalosis)

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33. Which of the following statements about antibiotic treatment of pneumonia is/are true?

Explanation

A: MRSA is common, C: It's the opposite, effective against negs not pos, D: AZ binds to 50S. E: Doxy binds to 30 S

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34.
Patients A, C, D, and E would be expected to have which of the following presentations?

Explanation

Tracheoesophageal fistula can present with polyhydramnios, frothing at the mouth, coughing, cyanosis, respiratory distress, and gets worse with feeding. It is diagnosed by inability to pass an NG tube, which shows up as a coiled tube on x-ray.

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35. A patient has the following ABGs:
pH: 7.40
PO2: 75
PCO2: 23
HCO3: 15 (increased anion gap)

What is/are the primary disturbance?

Explanation

Normal pH with abnormal PCO2 and HCO3 means that there are at least 2 disturbances. Since PCO2 is low there is a respiratory alkalosis, and since the bicarb is low, there is a metabolic acidosis (of the increased anion gap variety).

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36. A 71-year-old male resident of Minnesota regularly spends several winter months in Arizona to play golf in the sun. Last March he experienced a gradual onset of fever and a headache, followed by a nonproductive cough, myalgia, and profound fatigue. His local physician diagnosed bronchopneumonia on chest x-ray and prescribed azithromycin. The antibiotic provided no benefit, and ultimately the patient received two more courses of different empiric antibiotics. He returned to Minnesota with continued cough and fatigue, even though the fever had abated somewhat. Two months following the initial onset of symptoms, a bronchoscopy was performed.  What would you expect to see growing in culture?

Explanation

Coccidiomycosis is the endemic fungus in the SW US. Blasto is more common in the SE US, and Cryptococcus is seen in big cities with a lot of pigeons around. Aspergillus is possible, but not as likely considering the vignette and the lack of any distinctive x-ray changes. It is unlikely to be bacterial because repeated rounds of antibiotics did nothing for his symptoms.

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37.
Justin Bieber walks into your office and describes symptoms of hoarseness and lack of vocal control.  Flexible laryngoscopy is performed yielding the above image.  Which of the following treatments would you advise at this time?

Explanation

This is a vocal cord nodule, which is the result of repetitive trauma. All three treatments mentioned above will help reduce symptoms and prevent recurrence.

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38. A 70 year old woman presents to an inexperienced second year medical student with mild but persistent sinusitis, pharyngitis, and cough for the last few months.  The symptoms began in the summer.  CXR shows a streaky infiltrate.  The patient denies diarrhea, myalgias, arthralgias or rash.  Gram stain is unable to be attained but the wise old attending who already knows the diagnosis tells you that it would have been gram-negative.  What is the most likely diagnosis?

Explanation

Subacute and prolonged symptoms and streaky infiltrate are suggestive of either Mycoplasma or Chlamydophila. Patient also denies symptoms that are unique within the pneumonias to either Legionella (diarrhea) or Mycoplasma (myalgia, arthralgia). Chlamydophila is more common in 65-79 age range, and is gram-negative.

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39. A 65-year-old man presents to the ER with acute onset of SOB of 30 minutes' duration. Initially, he felt faint but did not lose consciousness. He is complaining of left-sided chest pain that worsens on deep inspiration. He has no history of cardiopulmonary disease. A week ago he underwent a total left hip replacement and, following discharge, was on bed rest for 3 days due to poorly controlled pain. He subsequently noticed swelling in his left calf, which is tender on examination. His current vital signs reveal a fever of 100.4°F (38.0°C), heart rate 112 bpm, BP 95/65, and an O2 saturation on room air of 91%.  A second year medical student from the University of Miami (main campus) orders a D-dimer test.  The results are negative.  What is the significance of the D-dimer test result?

Explanation

D-dimer can only rule out PE if the pre-test probability is low. Since this patient has a high probability of PE, the results of the test do nothing to rule out or in PE. The student would have known this had he gone to the regional campus and paid attention in Dr. L's class.

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40.
Select each answer choice that would be part of the differential diagnosis for this patient.

Explanation

The four T's of anterior mediastinal masses: Thyroid, Terrible lymphoma, Thymoma, Teratoma. This image is actually a thyroid goiter.

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41. A 1-year-old child presents with failure to thrive. By history, the child was born at the 50th percentile for weight, but has crossed multiple percentile lines despite having a ravenous appetite. The child has more bowel movements per day than other children of the same age, and the stools often look shiny and have an unusually foul smell. In addition, the child has been treated with multiple courses of antibiotics for a persistent, wet cough. On measurement, the child is small for age, with weight and length below the third percentile.  His mother states that his skin tastes 'salty' when she kisses him.  Which of the following would you also expect to see in this patient?

Explanation

The vignette describes a classic presentation of Cystic Fibrosis. A,C,D, and E are all seen in CF patients.

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42. Which of these is/are causes of hypoxemic-hypercapnic respiratory failure?

Explanation

Pneumonia is more likely to cause type 1 hypoxemic respiratory failure.

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Which of the following patients would you expect to have the worst...
True or false:  A negative PPD test rules out TB in a patient...
Which statement is true regarding TB treatment regimens?
A 70 year old man with a 50 pack year history of smoking presents to...
Which of the following are physical defense systems of the lung?
Which of the following is seen in Chronic Lung Disease (aka...
What is the most common type of cancer in the head and neck?
Why is it more difficult for the lungs to compensate for a metabolic...
A 20-year-old man presents to the emergency department with...
What grade of pulmonary hypertension is this image? 
A 64 year old former politician is seen by his primary care physician...
Which of these is not a phase of coughing?
Which of the following is characteristic of an exudate?
What is the most common cause of bronchiolitis in children?
Which of the following is/are true about Haemophilus influenza?
Which of these is a disadvantage of pressure controlled ventilation?
Which of these patients would be indicated to receive mechanical...
A 34-year-old man with a history of sex with men presents with 3...
A:    B:     Which of these are...
Which group of pulmonary hypertension is correctly matched with its...
A patient in the ICU has a PaO2 of 100 and an FiO2 of 40%.  The...
Which of the following is not one of the common constitutional...
Which statement is true regarding patients with latent TB infections?
Which of the following pulmonary diseases is properly matched up with...
The patient with the above angiogram has a BP of 80/60, and is...
A 50 year old male presents with productive cough, fever, and...
A 36-year-old woman presents with a 6-month history of gradually ...
A 3-month-old boy is referred by his pediatrician with intermittent ...
This sample was isolated from a 75 year old woman in the ICU who has...
What are the predominant features of this EKG, taken from a patient...
Which of the following would increase the likelihood of the condition...
For a patient with a pulmonary embolism, which is the most likely...
Which of the following statements about antibiotic treatment of...
Patients A, C, D, and E would be expected to have which of the...
A patient has the following ABGs:pH: 7.40PO2: 75PCO2: 23HCO3: 15...
A 71-year-old male resident of Minnesota regularly spends several ...
Justin Bieber walks into your office and describes symptoms of...
A 70 year old woman presents to an inexperienced second year medical...
A 65-year-old man presents to the ER with acute onset of SOB of 30 ...
Select each answer choice that would be part of the differential...
A 1-year-old child presents with failure to thrive. By history, the ...
Which of these is/are causes of hypoxemic-hypercapnic respiratory...
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