Respiratory Quiz - Module 11

Explanation
(false) Although LTRAs are effective, they are not as strong anti-inflammatories as inhaled corticosteroids (ICS).

Explanation
(true) Inhaled corticosteroids are the preferred first line therapy for moderate to severe asthmatics.

Explanation
LTRAs (Leukotriene Receptor Antagonists) are a good choice for patients who require mild controller therapy but can be managed without Inhaled Corticosteroids (ICS). This is because LTRAs are more convenient to use and have fewer side effects compared to ICS. LTRAs work by blocking the action of leukotrienes, which are substances in the body that cause inflammation and narrowing of the airways. By blocking leukotrienes, LTRAs help to reduce inflammation and improve breathing in patients with mild asthma. Therefore, it is true that LTRAs are a good choice for patients who require mild controller therapy but can be managed without ICS.

Explanation
LTRAs (Leukotriene Receptor Antagonists) are medications that can be added to the treatment plan for patients with asthma who are still experiencing symptoms despite being on low or medium doses of inhaled corticosteroids. LTRAs work by blocking the action of leukotrienes, which are substances in the body that cause inflammation and constriction of the airways. By adding LTRAs to the treatment regimen, it can help to further control symptoms and improve asthma control for these patients. Therefore, the statement is true.

Explanation
(false) Long acting beta 2 agonists are equally effective and perhaps more effective add on therapy (especially when given in a single inhaler), but have potential for more side effects and are contraindicated in children below the age of 5f

Explanation
Montelukast is a medication that is commonly used to treat asthma. It works by blocking the action of certain chemicals in the body that cause inflammation and constriction of the airways. Exercise-induced bronchospasm is a common symptom in patients with exercise-induced asthma, where physical activity triggers bronchial constriction and difficulty breathing. Studies have shown that Montelukast is effective and safe in preventing exercise-induced bronchospasm in these patients, making the statement true.

Explanation
(false) Duration of action is up to 24 hours after dosing

Explanation
(false) Aspirin induced asthma affects approximately 10% of adult patients with asthma

Explanation
Montelukast is effective in aspirin-induced asthma because it targets the common physiological pathway shared between aspirin metabolism and leukotrienes. Aspirin-induced asthma is characterized by an overproduction of leukotrienes, which are inflammatory mediators involved in the pathogenesis of asthma. Montelukast is a leukotriene receptor antagonist that inhibits the binding of leukotrienes to their receptors, reducing inflammation and bronchoconstriction in the airways. Therefore, it is particularly effective in treating aspirin-induced asthma, as it specifically targets the underlying mechanism of this condition.

Explanation
(false) the airway obstruction comes from swelling and mucous in the airways caused directly by the viral infection.

Explanation
(false) Patients have infection and non-allergic inflammation