Pg Blazer - Online Test Series 18 - Paediatrics
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All of the following are true of Beta thalassemia major, except:
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Splenomegaly
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Target cells on peripheral smear
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Microcytic hypochromic anemia
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Increased osmotic fragility
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Subject wise MCQ test - Paediatrics. For more online practice tests, go to PG Blazer Online Test Series.
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- 2.
Which of the following does not establish a diagnosis of congenital CMV infection in a neonate?
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Urine culture of CMV
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IgG CMV antibodies in blood
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Lntra nuclear inclusion bodies in hepatocytes
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CMV viral DNA in blood by polymerase chain reaction
Correct Answer
A. IgG CMV antibodies in bloodExplanation
Maternal IgG antibodies can pass into fetal circulation. Hence it is not possible to establish a diagnosis of congenital CMV infection in a neonate just by demonstrating the presence of IgG antibodies.Rate this question:
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- 3.
Which of the following haemoglobin (Hb) estimation will be diagnostically helpful in a case of beta thalassemia trait?
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HbF
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HbA1c
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HbA2
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HbH
Correct Answer
A. HbA2Explanation
Normal hemoglobin is composed predominantly of HbA1 – which is composed of 2 alpha chains and 2 beta chains. In beta thalassemia trait, there is decrease in production of beta chains of hemoglobin. But since the defect is minor, they will not have any clinical features and the peripheral smear may be normal. But there will be a compensatory increase in HbA2 which is composed of 2 alpha chains and 2 delta chains. Normally HbA2 constitutes about 1.5 to 3.5% of total hemoglobin. But in beta thalassemia trait, this increases to about 3.6 to 8%.Rate this question:
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- 4.
Which one of the following in the characteristic feature of juvenile myoclonic epilepsy?
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Myoclonic seizures frequently occur in the morning
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Complete remission is common
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Response to anticonvulsants is poor
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Associated absence seizures are present in majority of patients
Correct Answer
A. Myoclonic seizures frequently occur in the morningExplanation
Juvenile myoclonic epilepsy – Clinical features, treatment
It starts in early adolescence
Bilateral myoclonic jerks are seen
Mostly in the morning
Precipitated by sleep deprivation
The patient usually remains conscious during the episode
Associated with absence seizures and generalised tonic clonic seizures
Benign condition
Complete remission is uncommon
Positive family history may be present
Responds well to anticonvulsants
Drug of choice – ValproateRate this question:
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- 5.
A child is below the third percentile for height. His growth velocity is normal. But chronological age is more than skeletal age. The most likely diagnosis is:
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Constitutional delay in growth
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Genetic short stature
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Primordial dwarfism
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Hypopituitarism
Correct Answer
A. Constitutional delay in growthExplanation
The growth velocity and height for age in early childhood will be lower than normal in case of constitutional growth delay. But the final height attained will be normal. The skeletal maturation will be lower than expected for age.Rate this question:
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- 6.
A 15-year old female presented to the emergency department with history of recurrent epistaxis, hematuria and hematochezia. There was a history of profuse bleeding from the umbilicus stump at birth. Previous investigations revealed normal prothrombin time, activated partial thromboplastin time, thrombin time and fibrinogen levels. Her platelet counts as well as platelet function tests were normal but urea clot lysis test was positive. Which one of the following clotting factor is most likely to be deficient?
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Factor X
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Factor XI
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Factor XII
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Factor XIII
Correct Answer
A. Factor XIIIExplanation
Clinical features of Factor XIII deficiency :-
History of prolonged bleeding from umbilical stump
Delayed bleeding
Recurrent abortions
Diagnosis (Investigations) :-
Prothrombin time and Activated partial thromboplastin time are normal
--Factor XIII is needed for stabilization of fibrin clot
--Intrinsic and extrinsic pathways are not affected
Clot stability in 5M urea – qualitative test
--Normal clot remains stable in 5M urea
--But in cases of Factor XIII deficiency, the clot dissolves
--But it becomes positive only in very severe deficiency
Quantitative factor XIII assay – using photometryRate this question:
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- 7.
All of the following are features of prematurity in a neonate, except:
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No creases on sole
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Abundant lanugo
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Thick ear cartilage
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Empty scrotum
Correct Answer
A. Thick ear cartilageExplanation
Features of prematurity in a neonate:
Flat and soft pinna, cartilage not reaching upto periphery
Lightly pigmented scrotum with undescended testes
Absence of deep creases on sole
Poorly formed breast bud
Fuzzy hair
Prominent labia minora and clitoris (Labia majora are separated)Rate this question:
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- 8.
A normally developing 10 month old child should be able to do all of the following except:
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Stand alone
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Play peek a boo
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Pick up a pellet with thumb and index finger
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Build a tower of 3-4 cubes
Correct Answer
A. Build a tower of 3-4 cubesExplanation
A normal child can make a tower of 3 cubes by 18 months of age.Rate this question:
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- 9.
Which of the following is the principal mode of heat exchange in an infant incubator?
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Radiation
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Evaporation
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Convection
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Conduction
Correct Answer
A. ConvectionExplanation
Convection is the principal mode of heat exchange in an infant incubator. Convection involves the transfer of heat through the movement of fluids or gases. In an incubator, warm air is circulated around the infant to maintain a constant temperature. This circulation of warm air helps to distribute heat evenly and maintain a stable environment for the baby. Therefore, convection is the most important mode of heat exchange in an infant incubator.Rate this question:
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- 10.
The following are characteristic of autism except:
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Onset after 6 years of age
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Repetitive behavior
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Delayed language development
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Severe deficit in social interaction
Correct Answer
A. Onset after 6 years of ageExplanation
Features of autism usually appear before 3 years of age. (OP Ghai)Rate this question:
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Mar 17, 2023Quiz Edited by
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Jun 28, 2011Quiz Created by
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