OC Pharm Mt II

61 Questions | Total Attempts: 74

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OC Pharm Mt II


Questions and Answers
  • 1. 
    Describe what the role of cytokines are in the body and in the eye.
  • 2. 
    What is the MOA of Polymyxin B?
  • 3. 
    Indicate which of the following are NOT ADEs of ocular decongestants.
    • A. 

      Decreased IOP

    • B. 

      Punctate keratitis

    • C. 

      Palpitations & cardiac arrhythmias

    • D. 

      Brow ache

    • E. 

      Coronary occlusion

    • F. 

      Decreased blood glucose

    • G. 

      Dry eye

  • 4. 
    The maximum about of time one should use an ocular decongestant without seeing an eye doctor  is ____hours.
  • 5. 
    Pts with glaucoma should NOT use ocular decongestants without the advice of an eye doctor.
    • A. 

      True

    • B. 

      False

  • 6. 
    What is the concentration of phenyl that is used for ocular decongestants?
    • A. 

      0.05%

    • B. 

      0.12%

    • C. 

      0.2%

    • D. 

      0.5%

  • 7. 
    The PREG category for Phenyl is C.  What is the PREG category for tetrahydrozoline?
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

    • E. 

      Undetermined

  • 8. 
    Which ocular decongestant is found in decongestant/anti-H combos?
    • A. 

      Naphazoline

    • B. 

      Phenylephrine

    • C. 

      Oxymetazoline

    • D. 

      Tetrahydrozoline

  • 9. 
    Decongestant/Anti-A combos oftne include what type of vehicle to increase the viscosity of the solution (which increases contat time in the eye)?
    • A. 

      Hydroxypropyl methylcellulose

    • B. 

      Polyvinalpyrrolidine

    • C. 

      Polyvinyl alcohol

    • D. 

      Carboxymethylcellulose

    • E. 

      A & b

    • F. 

      A & c

    • G. 

      B & c

    • H. 

      B & d

  • 10. 
    Topical Anti-As may produce what ADE?
    • A. 

      Iritis

    • B. 

      Posterior synechiae

    • C. 

      Angle closure

    • D. 

      Reduced IOP

  • 11. 
    Which of the following is contraindicated when using antihistamines?
    • A. 

      TCAs (Triacyclic Anti-depressants)

    • B. 

      NSAIDs

    • C. 

      Topical corticosteroids

    • D. 

      MAOIs

  • 12. 
    The PREG category for antihistamines is ___.
  • 13. 
    Antihistamines are often used (although not recommeded) as a sleeping aid (esp. in elderly) due to it's potentially sedating effects
    • A. 

      True

    • B. 

      False

  • 14. 
    Epinastine is a dual antihistamine & mast cell stabalizer.  It has assocaited with increased risk of CNS effects and must be monitored closely.
    • A. 

      True

    • B. 

      False

  • 15. 
    Mast cell stabalizers have various MOAs, including intristic vasconstrictor activity, antihistaminic and anti-inflammatoyr activity.
    • A. 

      True

    • B. 

      False

  • 16. 
    Pure mast cell stabalizers are used for which type(s) of conjuctivitis?
    • A. 

      Perennial conjunctivitis

    • B. 

      Seasonal conjunctivitis

    • C. 

      GPC

    • D. 

      VKC

  • 17. 
    Which mast cell stabalizer has the fastest onset of action?
    • A. 

      Cromolyn

    • B. 

      Lodoxamide

    • C. 

      Nedocromil

    • D. 

      Pemiroast

  • 18. 
    Most mast cell stabalizers have a PREG category of B, however which of the following has PREG category C?
    • A. 

      Cromolyn

    • B. 

      Lodoxamide

    • C. 

      Nedocromil

    • D. 

      Pemirolast

  • 19. 
    When should therapy with ophthalmic mast cell stabalizers be initiated?
    • A. 

      ?

    • B. 

      ?

    • C. 

      ?

    • D. 

      ?

  • 20. 
    There are only a few oral corticosteroids that can be Rx'd by ODs, but they are not often used.
    • A. 

      True

    • B. 

      False

  • 21. 
    Which of the following dual antihistamine/mast cell stabalizer combos are available OTC?
    • A. 

      0.05% Azelastine SLN (Optivar)

    • B. 

      0.05% epinastine SLN (Elestat)

    • C. 

      0.1% olopatadine SLN (Patanol)

    • D. 

      0.025% ketotifen fumarate SLN (Alaway, Zatidor)

  • 22. 
    Corticosteroids are more effective in chronic, rather than acute conditions.
    • A. 

      True

    • B. 

      False

  • 23. 
    Steroids are usually not appropriate for use in mild ocular allergies because they are particularly damaging to ocular tissue with prolonged use.
    • A. 

      True

    • B. 

      False

  • 24. 
    Prolonged topical ophthalmic steroid use can cause:
    • A. 

      Ocular hemorrhage

    • B. 

      Ocular HTN & glaucoma

    • C. 

      Corneal melt

    • D. 

      Neovascularization of the iris

  • 25. 
    What should one suspect in any persistent corneal ulceration where a steroid has been used or is being used?
    • A. 

      Bacterial resistance to the steroid

    • B. 

      Fungal invasion

    • C. 

      Hypersensitivity to the steroid

    • D. 

      Herpes simplex keratitis

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