OC Pharm Mt II
- 1.Indicate which of the following are NOT ADEs of ocular decongestants.
- A.
Decreased IOP
- B.
Punctate keratitis
- C.
Palpitations & cardiac arrhythmias
- D.
Brow ache
- E.
Coronary occlusion
- F.
Decreased blood glucose
- G.
Dry eye
- 2.The maximum about of time one should use an ocular decongestant without seeing an eye doctor is ____hours.
- 3.Pts with glaucoma should NOT use ocular decongestants without the advice of an eye doctor.
- A.
True
- B.
False
- 4.What is the concentration of phenyl that is used for ocular decongestants?
- A.
0.05%
- B.
0.12%
- C.
0.2%
- D.
0.5%
- 5.The PREG category for Phenyl is C. What is the PREG category for tetrahydrozoline?
- A.
A
- B.
B
- C.
C
- D.
D
- E.
Undetermined
- 6.Which ocular decongestant is found in decongestant/anti-H combos?
- A.
Naphazoline
- B.
Phenylephrine
- C.
Oxymetazoline
- D.
Tetrahydrozoline
- 7.Decongestant/Anti-A combos oftne include what type of vehicle to increase the viscosity of the solution (which increases contat time in the eye)?
- A.
Hydroxypropyl methylcellulose
- B.
Polyvinalpyrrolidine
- C.
Polyvinyl alcohol
- D.
Carboxymethylcellulose
- E.
A & b
- F.
A & c
- G.
B & c
- H.
B & d
- 8.Topical Anti-As may produce what ADE?
- A.
Iritis
- B.
Posterior synechiae
- C.
Angle closure
- D.
Reduced IOP
- 9.Which of the following is contraindicated when using antihistamines?
- A.
TCAs (Triacyclic Anti-depressants)
- B.
NSAIDs
- C.
Topical corticosteroids
- D.
MAOIs
- 10.The PREG category for antihistamines is ___.
- 11.Antihistamines are often used (although not recommeded) as a sleeping aid (esp. in elderly) due to it's potentially sedating effects
- A.
True
- B.
False
- 12.Epinastine is a dual antihistamine & mast cell stabalizer. It has assocaited with increased risk of CNS effects and must be monitored closely.
- A.
True
- B.
False
- 13.Mast cell stabalizers have various MOAs, including intristic vasconstrictor activity, antihistaminic and anti-inflammatoyr activity.
- A.
True
- B.
False
- 14.Pure mast cell stabalizers are used for which type(s) of conjuctivitis?
- A.
Perennial conjunctivitis
- B.
Seasonal conjunctivitis
- C.
GPC
- D.
VKC
- 15.Which mast cell stabalizer has the fastest onset of action?
- A.
Cromolyn
- B.
Lodoxamide
- C.
Nedocromil
- D.
Pemiroast
- 16.Most mast cell stabalizers have a PREG category of B, however which of the following has PREG category C?
- A.
Cromolyn
- B.
Lodoxamide
- C.
Nedocromil
- D.
Pemirolast
- 17.When should therapy with ophthalmic mast cell stabalizers be initiated?
- A.
?
- B.
?
- C.
?
- D.
?
- 18.There are only a few oral corticosteroids that can be Rx'd by ODs, but they are not often used.
- A.
True
- B.
False
- 19.Which of the following dual antihistamine/mast cell stabalizer combos are available OTC?
- A.
0.05% Azelastine SLN (Optivar)
- B.
0.05% epinastine SLN (Elestat)
- C.
0.1% olopatadine SLN (Patanol)
- D.
0.025% ketotifen fumarate SLN (Alaway, Zatidor)
- 20.Corticosteroids are more effective in chronic, rather than acute conditions.
- A.
True
- B.
False
- 21.Steroids are usually not appropriate for use in mild ocular allergies because they are particularly damaging to ocular tissue with prolonged use.
- A.
True
- B.
False
- 22.Prolonged topical ophthalmic steroid use can cause:
- A.
Ocular hemorrhage
- B.
Ocular HTN & glaucoma
- C.
Corneal melt
- D.
Neovascularization of the iris
- 23.What should one suspect in any persistent corneal ulceration where a steroid has been used or is being used?
- A.
Bacterial resistance to the steroid
- B.
Fungal invasion
- C.
Hypersensitivity to the steroid
- D.
Herpes simplex keratitis
- 24.Dietary salt restriction and potassium supplementation may be necessary with topical steroid use.
- A.
True
- B.
False
- 25.Steroid use in contraindicated in active ocular herpes simplex infections.
- A.
True
- B.
False
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