SLE Assessment Exam 2

Tricyclic antidepressants (TCAs) do not cause peptic ulcers. Peptic ulcers are commonly caused by factors such as infection with Helicobacter pylori bacteria, prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs), excessive alcohol consumption, and smoking. TCAs are a class of medications primarily used to treat depression, anxiety, and other mental health conditions. They do not directly irritate the stomach lining or contribute to the development of peptic ulcers.

The rate of fluid given to the child per hour is 65ml. This is determined based on the child's weight (22kg) and the fact that he is dehydrated. The appropriate fluid replacement for a dehydrated child is typically calculated as 100ml/kg/day. Therefore, for a 22kg child, the fluid requirement would be 2200ml/day. To find the rate per hour, we divide this by 24, resulting in 91.67ml/hour. However, it is important to start rehydration slowly, so the rate is typically reduced to 65ml/hour initially.

Watchful waiting is the appropriate treatment choice in this case because the patient is young, the mass is small and mobile, and there are no axillary lymph nodes present. These characteristics suggest a low likelihood of malignancy. Watchful waiting involves closely monitoring the mass over time to assess for any changes or growth. If there are no significant changes, further intervention may not be necessary. This approach avoids unnecessary invasive procedures and potential complications associated with surgery.

Lobular carcinoma is a type of breast malignancy that can occur in both breasts simultaneously, making it bilateral. This type of cancer starts in the milk-producing glands of the breast and can spread to other parts of the body. Ductal ectasia, Paget's disease, and infiltrating ductal carcinoma are all types of breast malignancies that typically affect only one breast and are therefore not bilateral.

Smoking has the greatest exogenous side effect on osteoporosis because it decreases the production of estrogen, which is important for maintaining bone density. Smoking also increases inflammation and oxidative stress, both of which can contribute to bone loss. Additionally, smoking impairs the absorption of calcium, an essential mineral for bone health. Therefore, smoking can accelerate bone loss and increase the risk of fractures in individuals with osteoporosis.

Due to the prolonged absence of menstruation (amenorrhea) in a female who does a lot of training, her risk of infertility is increased. Amenorrhea can be caused by excessive exercise, which can disrupt the hormonal balance necessary for ovulation and fertility. This disruption can make it difficult for the woman to conceive.

Acetaminophen is often considered the best management for a patient with chronic pain. It is a commonly used over-the-counter pain reliever that can effectively reduce pain and fever. It is generally safe and well-tolerated when used as directed, making it a suitable option for long-term pain management. Acetaminophen is particularly recommended for individuals who cannot take nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or opioids like morphine due to contraindications or side effects. Naloxone, on the other hand, is an opioid antagonist used to reverse opioid overdose, and morphine is a potent opioid analgesic typically reserved for severe pain. Therefore, acetaminophen is the best choice among the given options for managing chronic pain.

The patient's symptoms of neurological deficit, congested neck veins, and tachycardia suggest a diagnosis of wet beriberi. Wet beriberi is a condition caused by thiamine (vitamin B1) deficiency, which can occur due to a diet lacking in essential nutrients like polish white rice. Thiamine is important for the proper functioning of the nervous system and cardiovascular system. Symptoms of wet beriberi include cardiovascular abnormalities such as high heart rate and congested neck veins, as well as neurological symptoms like muscle weakness and sensory disturbances.

The patient's symptoms of chest pain, sweating, and being pulseless for 4 hours, along with the presence of an ECG, suggest a severe cardiac emergency. Ventricular fibrillation is a life-threatening arrhythmia characterized by chaotic, uncoordinated contractions of the ventricles. It can result in cardiac arrest and requires immediate defibrillation to restore a normal heart rhythm. Atrial fibrillation, WPW (Wolff-Parkinson-White syndrome), and Torsade de pointas are not typically associated with the same level of severity and immediate danger as ventricular fibrillation.

An isotope scan is the most appropriate next step in this case. The symptoms of dark urine and dark brown stool, along with a positive occult test, suggest the presence of blood in the gastrointestinal tract. An isotope scan, also known as a nuclear medicine scan, can help identify the source of bleeding by tracing the movement of a radioactive substance through the body. This test can provide valuable information about the location and severity of the bleeding, helping to guide further diagnostic and treatment decisions. X-ray, barium study, and abdominal ultrasound may not provide the same level of detail and specificity in this scenario.

The patient is experiencing a false perception of aliens being present around the building, which is not based on reality. This is a classic symptom of hallucination, where a person sees, hears, or feels things that are not actually there. Delusion refers to a fixed false belief, compulsion is an irresistible urge to perform certain actions, and obsession is an intrusive and persistent thought or idea. However, none of these options accurately describe the patient's experience of perceiving aliens.

To avoid excessive bleeding during surgery to remove a right-sided ovarian mass in a 54-year-old female with chronic pelvic pain, the surgeon should ligate the suspensory ligament. The suspensory ligament, also known as the infundibulopelvic ligament, contains the ovarian vessels which supply blood to the ovary. By ligating this ligament, the surgeon can prevent excessive bleeding during the procedure. The other structures listed, such as the mesosalpinx, round ligament, and transverse cervical ligament, are not directly involved in supplying blood to the ovary and therefore would not be the appropriate choice to ligate in this situation.

Operating on an infant born with a hemangioma on the right eyelid within the first week is the appropriate time to prevent amblyopia. Amblyopia, also known as lazy eye, occurs when the brain favors one eye over the other, leading to reduced vision in the weaker eye. Hemangiomas are abnormal growths of blood vessels, and if left untreated near the eye, they can cause visual obstruction and lead to amblyopia. By operating within the first week, the hemangioma can be removed or reduced in size, allowing for normal visual development and preventing amblyopia.

Based on the information provided, the 19-year-old sexually active lady is otherwise healthy and has normal pap smear and investigations. Therefore, it is reasonable to suggest that her next check-up can be scheduled after 3 years. This is because annual check-ups may not be necessary for individuals with no significant health issues and normal test results. However, it is important to note that this recommendation may vary based on individual factors and medical guidelines.

Digoxin is contraindicated in hypertrophic obstructive cardiomyopathy. This is because digoxin increases the force of contraction of the heart muscle, which can worsen the obstruction of blood flow in the heart. Therefore, it is not recommended to use digoxin in patients with this condition as it can potentially worsen their symptoms and lead to complications.

Tacrolimus is a suitable medication to add for a 10-year-old child with eczema who is already using 1% hydrocortisone. Tacrolimus is an immunosuppressant that helps to reduce inflammation and itching associated with eczema. It is often used as a second-line treatment when topical corticosteroids like hydrocortisone are not effective or cannot be used. Tacrolimus is applied topically and is generally well-tolerated, making it a good option for children. Cyclosporine and dexamethasone are not commonly used for eczema treatment in children.

Alprazolam is the best drug for moderate to severe anxiety because it is a benzodiazepine that works by enhancing the effects of a neurotransmitter called GABA in the brain, which helps to reduce anxiety and promote relaxation. It has a rapid onset of action and is effective in managing symptoms of anxiety disorders. Imipramine is a tricyclic antidepressant, Phenelzine is a monoamine oxidase inhibitor, and Haloperidol is an antipsychotic medication, none of which are specifically indicated or considered first-line treatments for anxiety disorders.

Granuloma annulare is a chronic skin condition characterized by the formation of small, raised bumps in a ring-like or annular pattern. It is more common in children and young adults. The eruption is usually non-pruritic, meaning it does not cause itching. In this case, the 12-year-old female has a non-pruritic annular eruption on her right foot for 8 months, which is consistent with granuloma annulare. The lack of response to miconazole, an antifungal medication, suggests that the condition is not caused by a fungal infection such as tinea corporis.

FNA with cytology is the appropriate next step in this case because the patient has a tender mobile mass in her breast, which raises concern for a possible breast tumor. FNA (fine needle aspiration) with cytology involves using a thin needle to extract cells from the mass and examining them under a microscope. This procedure can help determine if the mass is benign or malignant, providing valuable information for further management. Mammogram and biopsy may be considered later depending on the FNA results. Follow-up for the next cycle is not appropriate as further evaluation is needed.

Chlorpropamide is not advised to be given to elderly patients due to its long half-life, which can increase the risk of hypoglycemia. Digoxin is a medication used for heart conditions, thyroxin is a hormone replacement therapy for hypothyroidism, and cimetidine is a medication used to reduce stomach acid. These drugs may be prescribed to elderly patients depending on their specific medical conditions.

Based on the given information, the young healthy male has abdominal pain after playing basketball. The examination is fine except for left paraumbilical tenderness. In this scenario, the best course of action would be to send the patient home and reassess within 48 hours. This approach allows for observation and monitoring of the symptoms to see if they improve or worsen over time. It is a conservative approach that avoids unnecessary tests or interventions unless the symptoms worsen or new symptoms develop.

Paracetamol is considered the best first-line drug treatment for osteoarthritis pain because it is a safe and effective option with minimal side effects. It is a non-opioid analgesic that helps to relieve pain and reduce inflammation. Paracetamol is easily accessible over-the-counter and is generally well-tolerated by most individuals. It is a suitable choice for managing mild to moderate osteoarthritis pain and is often recommended as an initial treatment before considering other options such as NSAIDs or opioids.

The correct answer is to discard their clothes. After being exposed to radiation, it is important to remove any contaminated clothing to prevent further exposure and spread of radiation. This is a crucial step in managing the situation and ensuring the safety of the workers and others around them.

Local decongestion is the correct answer because vasomotor rhinitis is a condition characterized by nasal congestion due to the dilation of blood vessels in the nasal passages. Local decongestion helps to reduce this congestion by constricting the blood vessels, thereby relieving the symptoms. Local antihistamine and local steroid may be used in other types of rhinitis, but they may not be as effective in vasomotor rhinitis. Systemic antibiotics are not indicated in vasomotor rhinitis as it is not caused by a bacterial infection.

The correct answer is HELLP. HELLP syndrome is a serious condition that can occur during pregnancy. It is characterized by Hemolysis (breakdown of red blood cells), Elevated Liver enzymes, and Low Platelet count. In this case, the pregnant lady presented with bleeding from gums, which could be due to low platelet count. The palpable spleen and platelet count of 50,000 further support the diagnosis of HELLP syndrome.

All of the above drugs would be safe to continue during breastfeeding. This is because they have been found to have minimal levels in breast milk and have not been associated with significant adverse effects in breastfed infants. It is important to note that the benefits of breastfeeding should be weighed against the potential risks of medication exposure, and the decision should be made in consultation with the patient's healthcare provider.

The most common site of origin of the tumor associated with the Zollinger-Ellison syndrome is the pancreas. Zollinger-Ellison syndrome is a rare condition characterized by the presence of gastrin-secreting tumors called gastrinomas. These tumors are most commonly found in the pancreas, although they can also occur in other parts of the digestive system such as the duodenum. The excessive production of gastrin by these tumors leads to increased acid production in the stomach, causing symptoms such as peptic ulcers, abdominal pain, and diarrhea. Therefore, the pancreas is the correct answer as it is the primary site of origin for these tumors.

In this case, the correct answer is to prescribe oral antibiotics. The patient's symptoms of a tender, red nodule on the lacrimal duct site suggest an infection. Prescribing oral antibiotics would be the appropriate initial step to treat the infection before referring the patient to an ophthalmologist for further evaluation and management. Topical antibiotics may not be sufficient to treat the infection, and topical steroids would not be appropriate as they may worsen the infection. Doing nothing would not address the patient's symptoms and could potentially lead to complications.

The correct answer is INH alone. If a child has a positive skin test for tuberculosis (TB) and previously tested negative, it indicates a recent infection. In this case, the recommended treatment is Isoniazid (INH) alone. INH is a first-line medication used to treat TB and is effective in preventing the development of active TB disease in individuals with latent TB infection. The use of other medications such as Rifampicin, Streptomycin, or a full regimen for TB would not be necessary in this scenario.

The correct answer is routine ophthalmology referral. In an old diabetic patient with mild early cataract and retinal pigmentation with Drusen formation, it is important to refer the patient to an ophthalmologist for further evaluation and management. This is because cataracts and retinal pigmentation can affect vision and may require specialized treatment or surgery. A routine referral allows the ophthalmologist to assess the patient's condition and determine the appropriate course of action.

Intolerance to failure to proteins and carbohydrates can be a common cause of failure to thrive. This condition refers to the inability of the body to properly digest and absorb proteins and carbohydrates, leading to inadequate nutrition and poor growth. It can result from various factors such as enzyme deficiencies or gastrointestinal disorders. If a person is unable to break down and utilize these essential nutrients, it can lead to weight loss, developmental delays, and overall failure to thrive.

The given description of "Acne about 1cm with pus" indicates that there is inflammation present in the acne. Inflammatory acne is characterized by redness, swelling, and the presence of pus. This stage of acne occurs when the hair follicles become clogged with excess oil, dead skin cells, and bacteria, leading to an inflammatory response. Therefore, the correct stage in this case would be "Inflammatory."

Bupropion is contraindicated for use in migraine because it can lower the seizure threshold and increase the risk of seizures, which is already elevated in patients with migraine. Migraine is a neurological condition characterized by recurrent headaches, and individuals with this condition are already prone to seizures. Therefore, using bupropion in migraine patients can potentially exacerbate their condition and lead to serious complications. It is important to avoid bupropion in these patients and consider alternative treatment options.

The correct answer is Hypothyroidism. This is because the baby is presenting with hypotonia, areflexia, fasciculations of the tongue, and respiratory distress, which are all characteristic features of hypothyroidism in newborns. The normal nerve conduction studies indicate that there is no nerve damage or dysfunction, ruling out conditions like Guillain-Barre syndrome and myasthenia gravis. Cerebral palsy is also unlikely as the baby was born full term with a normal pregnancy. The presence of pneumonitis on x-rays may be a secondary finding in hypothyroidism.

Cystoscopy is the best investigation for a patient presenting with gross hematuria. This procedure involves inserting a thin tube with a camera into the bladder to examine the urinary tract for any abnormalities or sources of bleeding. It allows direct visualization of the bladder and urethra, making it a valuable diagnostic tool in identifying the cause of hematuria. Renal biopsy is not necessary in this scenario as the focus is on the lower urinary tract. Urine culture may be useful to detect any urinary tract infections, but it does not provide direct visualization. Ultrasound (U/S) can be helpful in assessing the kidneys and urinary system, but cystoscopy provides more accurate information in this case.

During pregnancy, there is a natural increase in blood volume in order to support the growing fetus. This increased blood volume can have clinical significance in the management of severely injured, gravid women. One of the effects of this hypervolemia is that it increases the volume of blood loss required to produce maternal hypotension. This means that a larger amount of blood loss would be needed to cause a drop in blood pressure, which can be important in determining the severity of the injury and the appropriate management.

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The most likely investigation that the employer would do in this case is a Skull XR (skull x-ray). This is because the worker hit his head on a machine, and a skull x-ray is a commonly used diagnostic test to assess for fractures or other abnormalities in the skull. The fact that the worker's examination (O/E) was normal suggests that there may not be any immediate concerns, but a skull x-ray would still be warranted to rule out any potential injuries.

Placenta abruption is a condition where the placenta separates from the uterine wall before delivery. This can cause fetal distress because the baby may not receive enough oxygen and nutrients from the placenta. Fetal distress refers to any signs or symptoms that indicate the baby is in distress, such as changes in heart rate, decreased movement, or abnormal positioning. Therefore, fetal distress is special or significant in cases of placenta abruption as it indicates potential harm to the baby's well-being.

The patient's history of normal deliveries and the presence of high FSH, high LH, and low estrogen levels suggest a diagnosis of Asherman syndrome. Asherman syndrome is characterized by the formation of scar tissue in the uterus, usually as a result of previous D&C procedures. This can lead to menstrual abnormalities, infertility, and hormonal imbalances. The high FSH and LH levels indicate ovarian dysfunction, which is commonly associated with Asherman syndrome. Turner syndrome is unlikely as it is a genetic condition that causes various physical and developmental abnormalities. Sheehan syndrome is also unlikely as it is characterized by postpartum pituitary gland necrosis, which would not explain the hormonal imbalances seen in this patient. Ovarian failure could be a possibility, but the specific history of D&C and normal deliveries points more towards Asherman syndrome.

The frequency of eye examination for a patient who does not complain of anything and has no history of medical illness is typically recommended to be every 1-2 years. Regular eye examinations are important for maintaining good eye health and detecting any potential issues early on.

The most likely diagnosis in this case is occlusion of the central retinal vein. This is supported by the sudden painless loss of vision, swollen optic disc, and presence of multiple flame-shaped and blot haemorrhages. Occlusion of the central retinal vein can lead to impaired blood flow and subsequent damage to the optic nerve, resulting in vision loss.

Acyclovir is a medication commonly used to treat viral infections, including herpes. Postherpetic neuralgia is a complication that can occur after a herpes infection, causing chronic pain in the affected area. Acyclovir has been found to reduce the risk of developing postherpetic neuralgia by effectively treating the underlying viral infection. Corticosteroids, on the other hand, are not specifically targeted towards viral infections and may not have the same effect in preventing postherpetic neuralgia. Therefore, the correct answer is acyclovir only.

Open reduction with internal fixation is the correct management for a child with a spiral type radial fracture. This involves surgically realigning the fractured bone fragments and using internal fixation devices such as plates, screws, or rods to stabilize the fracture. Splinting alone may not provide sufficient stability for proper healing of the fracture. Referring to pediatric or orthopedic specialists may be necessary for further evaluation and treatment, but the initial management would involve open reduction with internal fixation.

The likely diagnosis in this case is Telogen Effluvium. Telogen Effluvium is a condition characterized by temporary hair loss due to a disruption in the hair growth cycle. In this case, the presence of clubbed and attenuated hairs suggests that the hair loss is likely due to a disturbance in the normal hair growth process. Additionally, the normal examination of the child and the localized hair loss at the temporal area further support the diagnosis of Telogen Effluvium. Trichotillomania, alopecia areata, and tinea capitus are less likely diagnoses in this case.

Digoxin is a medication commonly used to treat certain heart conditions, including abnormal heart rhythms. In this case, the baby in the NICU has a heart rate of 300, which is considered abnormally high. Digoxin helps to slow down the heart rate and can be administered to the baby to bring it back to a normal range. It is a suitable choice in this situation to help regulate the baby's heart rate.

The correct answer is "Decrease the availability of serotonin." This mechanism of action suggests that the drug used in the treatment of anxiety works by reducing the levels of serotonin, a neurotransmitter in the brain that is associated with mood regulation. By decreasing the availability of serotonin, the drug may help to alleviate symptoms of anxiety and promote a sense of calmness.

Glucagon is a hormone produced by the pancreas that helps regulate blood sugar levels. It stimulates the liver to release stored glucose into the bloodstream. In the given scenario, the patient has recurrent vomiting and a high hematocrit level of 65, which indicates dehydration. Glucagon can cause nausea and vomiting as a side effect, and in this case, it is likely that the elevated glucagon levels are causing the patient's symptoms. Therefore, the correct answer is Glucagon.

Long-term use of phenytoin can lead to several complications, including osteoporosis, macrocytosis, and ataxia. However, osteomalacia is not a complication of long-term use of phenytoin. Osteomalacia refers to the softening of the bones due to a deficiency in vitamin D or calcium, which can result in weakened bones and increased risk of fractures. While phenytoin can affect bone health, it is more commonly associated with osteoporosis, which is the loss of bone density. Therefore, osteomalacia is the exception among the listed complications.

Secondary data analysis is considered the most powerful epidemiologic study because it involves using existing data that has already been collected for other purposes. This allows researchers to analyze large datasets and explore associations between variables without the need for expensive and time-consuming data collection. Secondary data analysis can provide valuable insights into population health trends, disease patterns, and risk factors, making it a valuable tool in epidemiological research.