Chemotherapy Competency Week 1

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Mtoupe
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  • 1/10 Questions

    You are making your rounds in the treatment room when you notice an IV rate that is inconsistent with the drug & volume being infused.  Your next action should be

    • Ignore it. It is not your patient.
    • Pause the infusion. Find the patients nurse and clarify rate desired.
    • Leave as is. Find the patients nurse and clarify rate desired.
    • Change the rate and say nothing.
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Training Quizzes & Trivia
About This Quiz

Weekly review of knowledge and skills essential for safe administration of chemotherapy.
Complete quiz weekly and your name will be entered in drawing for 10 tickets equaling 1 hour of PTO.
Please email me your questions, answers, and supportive documentaton for next weeks quiz!


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  • 2. 

    What teaching is necessary in the patient who is expected to experience mucositis?

    • Oral assessment

    • Mouth care

    • Nutritional support

    • All of the above

    Correct Answer
    A. All of the above
    Explanation
    Instruct the patient and family on the proper technique to use in assessing the oral cavity. Successful mouth care begins with chemotherapy administration to maintain mouth hygiene and moisture and ameliorate mucositis. Patients who will develop mucositis at home need to be provided with instructions and solutions for mouth care. If the patient develops mucositis, his or her ability to eat may be compromised. Provide eating hints for ways to maintain nutrition. (Beck, 2004; Polovich, White, & Kelleher, 2005)

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  • 3. 

    Your patient asks, "Why exactly does chemotherapy make you lose your hair?"  How will you answer?

    • "I'm not sure. Your should ask your provider during your next visit."

    • "Cells responsible for hair growth are rapidly dividing and chemotherapy kills rapidly dividing cells."

    • "Wearing an ice cap on your head will prevent hair loss."

    • "Don't worry. It happens to everyone. It will grow back>"

    Correct Answer
    A. "Cells responsible for hair growth are rapidly dividing and chemotherapy kills rapidly dividing cells."
    Explanation
    At any given time, 85-90% of hair is in the growth phase. Alopecia is a misunderstood and feared side effect of therapy. By understanding the reason for hair loss, patients will be better able to cope with it. (Polovich, White, & Kelleher, 2005; Reeves, 2004).

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  • 4. 

    Advanced age causes an increased risk of neutropenia.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    As people age, the bone marrow becomes fibrotic, and production of white blood cells is slowed. There is a smaller white blood cell reserve in the marrow of the elderly. (Camp-Sorrell, 2005; Polovich, White, & Kelleher, 2005; Wujcik, 2004.

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  • 5. 

    What drug is given with fluorouracil (Adrucil/5FU)  to potentiate its effects and with methotrexate to protect normal cells?

    • Leucovorin

    • Vitamin B12

    • Folate

    • Camptosar

    Correct Answer
    A. Leucovorin
    Explanation
    Leucovorin is similar to folic acid. Methotrexate works by competing with the folic acid in cancer cells, leading to a folic acid deficiency and cancer cell demise. Leucovorin is given to block the uptake of methotrexate into normal cells (after 24 hours to allow methotrexate to exert its anti-cancer effect) that also become folic acid deficient after methotrexate administration. Fluorouracil has a very short life span in blood and body tissues. Leucovorin enhances the binding of fluorouracil to an enzyme that prolong its life span in the blood and body tissues, which can lead to a greater anti-cancer effect. (Camp, Gullatte, Gilmore, & Hutcherson, 2001; Polovich, White, & Kelleher, 2005)

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  • 6. 

    A common Benzodiazepine used to treat nausea and vomiting in chemotherapy is

    • Aloxi (palonosetron)

    • Emend (aprepitant)

    • Ativan (lorazepam)

    • Compazine (prochlorperazine)

    Correct Answer
    A. Ativan (lorazepam)
    Explanation
    Although lorazapam is frequently given for acute and delayed nausea and vomiting for its sedating and amnesic effect, lorazepam is best used for anticipatory nausea and vomiting. (Polovich, White, & Kelleher, 2005; Wickham, 2004).

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  • 7. 

    What is often the first symptom of  oral mucositis?

    • Pain and ulceration in the mouth and throat

    • Mouth bleeding

    • Visible ulcerations in the mouth

    • Burning sensation in the mouth

    Correct Answer
    A. Burning sensation in the mouth
    Explanation
    The burning sensation in the mouth is generally followed by difficulty swallowing or a sensation of a lump in the throat. signs and symptoms of advanced mucositis are esophageal pain or burning, mouth swelling, excessive secretions, redness in the mouth and throat, mouth bleeding, ulcerated areas, and pain in the mouth and throat. ( Beck, 2004; Polovich, White, & Kelleher, 2005.

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  • 8. 

    What non-hematopoietic secondary malignancy is associated with cyclophosphamide (Cytoxan) administration?

    • Bladder Cancer

    • Uterine cancer

    • Lung cancer

    • Leukemia

    Correct Answer
    A. Bladder Cancer
    Explanation
    The metabolite from cyclophosphamide, acrolein is thought to cause bladder cancer as a secondary malignancy for some patients. (Camp et al. 2001; Cleri & Haywood, 2002;, Polovich, White, and Kelleher, 2005)

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  • 9. 

    When does the nadir most commonly occur?

    • 3-5 days post chemotherapy

    • 10-14 days post chemotherapy

    • 7-10 days post chemotherapy

    • 14-18 days post chemotherapy

    Correct Answer
    A. 7-10 days post chemotherapy
    Explanation
    Although 7-10 days is the most common time for nadir, the nadir varies with different drugs and drug classes. (Camp et al., 2001; Cleri and Haywood, 2002; Polovich, White, & Kelleher, 2005).

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  • 10. 

    Mrs Smith will be receiving T/C for her breast cancer.  Taxotere iIV s ordered at 75 mg per m2 and Cytoxan IV is ordered at 600 mg per m2.  Mrs. Smith is 5'7" and weighs 146 pounds.  Her expected dose of each of these drugs would be

    • Taxotere 133 mg, Cytoxan 700 mg.

    • Taxotere 125 mg, Cytoxan 1000mg.

    • Taxotere 133 mg., Cytoxan 1062 mg.

    • Taxotere 120 mg., Cytoxan 1062 mg.

    Correct Answer
    A. Taxotere 133 mg., Cytoxan 1062 mg.
    Explanation
    BSA = 1.77 m2. (rounded from 1.769 m2)
    Taxotere 75mg x 1.77m2 = 132.75 rounded to 133 mg
    Cytoxan 600 mg x 1.77 =1062

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  • Current Version
  • Mar 21, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Nov 03, 2013
    Quiz Created by
    Mtoupe
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