Blood Cell Morphology Quiz

Explanation
Target cells, also known as codocytes, are a type of red blood cell morphology characterized by a central bullseye-like area of hemoglobin surrounded by a pale ring. This gives the cell a target-like appearance. Target cells can be seen in various conditions such as liver disease, thalassemia, and hemoglobinopathies. The name "target cells" is derived from their distinctive appearance under a microscope.

Explanation
An echinocyte is a type of red blood cell morphology characterized by the presence of numerous small, evenly spaced projections on the cell surface. These projections give the cell a spiky or crenated appearance. Echinocytes can be caused by various factors, including certain diseases, medications, or mechanical damage to the red blood cells. They can be seen in conditions such as liver disease, kidney disease, or electrolyte imbalances. The presence of echinocytes in a blood sample can be indicative of an underlying health issue and may warrant further investigation.

Explanation
Macrocytic is the term used to describe this RBC based on its size.

Explanation
Spherocytes are a type of red blood cell morphology characterized by a round shape and a lack of central pallor. They are typically smaller and denser than normal red blood cells, and they can be seen in conditions such as hereditary spherocytosis, autoimmune hemolytic anemia, and certain drug reactions. The absence of central pallor is a key distinguishing feature of spherocytes, and they can be identified using a peripheral blood smear.

Explanation
Howell-Jolly bodies are small, round, dark-staining structures that can be seen within red blood cells (RBCs) under a microscope. They are remnants of the cell nucleus that should have been removed during the maturation process of RBCs in the bone marrow. However, in certain conditions such as after splenectomy or in individuals with splenic dysfunction, Howell-Jolly bodies may be present in the circulating RBCs. Their presence can indicate a reduced ability of the spleen to filter abnormal RBCs, and they are often seen in conditions such as sickle cell disease, thalassemia, and autoimmune hemolytic anemia.

Explanation
A keratocyte is a type of red blood cell morphology characterized by the presence of two or more horn-like projections on the cell membrane. These projections give the cell a "helmet" or "horned" appearance. This morphology is often seen in conditions such as iron deficiency anemia or liver disease.

Explanation
Rouleaux formation refers to the stacking or clumping of red blood cells (RBCs) in a linear or coin-like fashion, resembling a stack of coins. This arrangement occurs due to the presence of certain proteins or abnormalities in the blood, which cause the RBCs to stick together. Rouleaux formation can be a normal finding in some individuals, but it can also be associated with certain medical conditions, such as multiple myeloma or inflammatory diseases. Identifying rouleaux formation on a blood film can provide valuable information about the patient's health and help in diagnosing underlying conditions.

Explanation
A drepanocyte is a type of red blood cell that has an elongated, crescent or sickle shape. This abnormal shape is commonly seen in individuals with sickle cell disease. Drepanocytes can cause blockages in blood vessels, leading to reduced blood flow and oxygen delivery to tissues. The name "drepanocyte" is derived from the Greek word "drepanon," meaning sickle or scythe, which accurately describes the shape of these cells.