Pharma_blood_heparin_plus_quiz_dr_aboshousha

1. Low molecular weight heparins differ from unfractionated heparin in that:

They selectively inhibit factor Xa

They do not significantly prolong clotting time

They are metabolized slowly and have longer duration of action

All of the above are correct

Higher efficacy in arterial thrombosis

Less frequent dosing

Higher and more consistent subcutaneous bioavailability

Laboratory monitoring of response not required

Heparan sulfate

Dextran sulfate

Protamine sulfate

Ancrod

Direct inhibition of prothrombin to thrombin conversion

Facilitation of antithrombin III mediated inhibition of factor Xa and thrombin

Activation of antithrombin III to inhibit factors IX and XI

Inhibition of factors XIIa and XIIIa

Bleeding time

Activated partial thromboplastin time

Prothrombin time

Both ‘B’ and ‘C’