Pharma_blood_heparin_plus_quiz_dr_aboshousha

5 Questions | By Hazemaboshousha | Updated: Apr 22, 2017 | Attempts: 153

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Questions and Answers

1.

The primary mechanism by which heparin prevents coagulation of blood is:
- A.
  
  Direct inhibition of prothrombin to thrombin conversion
- B.
  
  Facilitation of antithrombin III mediated inhibition of factor Xa and thrombin
- C.
  
  Activation of antithrombin III to inhibit factors IX and XI
- D.
  
  Inhibition of factors XIIa and XIIIa
Correct Answer
B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombin
2.

Low doses of heparin prolong:
- A.
  
  Bleeding time
- B.
  
  Activated partial thromboplastin time
- C.
  
  Prothrombin time
- D.
  
  Both ‘B’ and ‘C’
Correct Answer
B. Activated partial thromboplastin time
3.

Low molecular weight heparins differ from unfractionated heparin in that:
- A.
  
  They selectively inhibit factor Xa
- B.
  
  They do not significantly prolong clotting time
- C.
  
  They are metabolized slowly and have longer duration of action
- D.
  
  All of the above are correct
Correct Answer
D. All of the above are correct
4.

Low molecular weight heparins have the following advantages over unfractionated heparin EXCEPT:
- A.
  
  Higher efficacy in arterial thrombosis
- B.
  
  Less frequent dosing
- C.
  
  Higher and more consistent subcutaneous bioavailability
- D.
  
  Laboratory monitoring of response not required
Correct Answer
A. Higher efficacy in arterial thrombosis
5.

The following can be used to antagonise the action of heparin in case of overdose:
- A.
  
  Heparan sulfate
- B.
  
  Dextran sulfate
- C.
  
  Protamine sulfate
- D.
  
  Ancrod
Correct Answer
C. Protamine sulfate

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Apr 22, 2017

Quiz Edited by
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Apr 22, 2017

Quiz Created by
Hazemaboshousha

Pharma_blood_heparin_plus_quiz_dr_aboshousha

The primary mechanism by which heparin prevents coagulation of blood is:

Low doses of heparin prolong:

Low molecular weight heparins differ from unfractionated heparin in that:

Low molecular weight heparins have the following advantages over unfractionated heparin EXCEPT:

The following can be used to antagonise the action of heparin in case of overdose: