Bcid Module 5 Quiz

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| By Nicole Siska
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Nicole Siska
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Quizzes Created: 4 | Total Attempts: 482
| Attempts: 120
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  • 1/12 Questions

    Which piece of information would not be helpful in determining appropriate antibiotic therapy?

    • Cell wall membrane scan
    • Resistance marker detection
    • Antibiogram
    • Antimicrobial susceptibility profile
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About This Quiz

Quiz questions covering the material in Module 5 of the Blood Culture Training series

Bcid Module 5 Quiz - Quiz

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  • 2. 

    Gram-negative bacteria are usually more resistant to antibiotics than Gram-positive bacteria.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Gram-negative bacteria have an outer membrane that provides an additional barrier against antibiotics, making them more resistant compared to Gram-positive bacteria which lack this outer membrane. The outer membrane of Gram-negative bacteria contains lipopolysaccharides that act as a protective shield, preventing antibiotics from entering the cell. Additionally, Gram-negative bacteria possess efflux pumps that can actively pump out antibiotics, further contributing to their resistance. Therefore, it is true that Gram-negative bacteria are usually more resistant to antibiotics than Gram-positive bacteria.

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  • 3. 

    Beta-lactam antibiotics have which of the following mechanism of action:

    • Inhibit cell wall synthesis

    • Inhibit nucleic acid synthesis

    • Inhibit bacterial conjugation

    • Inhibit protein synthesis

    Correct Answer
    A. Inhibit cell wall synthesis
    Explanation
    Beta-lactam antibiotics inhibit cell wall synthesis. The cell wall is essential for the structural integrity of bacteria, and beta-lactam antibiotics target enzymes called penicillin-binding proteins (PBPs) that are involved in the formation of the cell wall. These antibiotics bind to PBPs and prevent them from cross-linking the peptidoglycan strands, which weakens the cell wall and leads to cell lysis. By inhibiting cell wall synthesis, beta-lactam antibiotics effectively kill the bacteria and are widely used to treat bacterial infections.

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  • 4. 

    Which of the following is a benefit of resistance gene detection over AST?

    • It is much faster

    • It shows physical response of bacteria to a specific dose of antibiotic

    • It relies on growth of the organism in culture

    • It tells the minimum inhibitory concentration of antibiotic to use

    Correct Answer
    A. It is much faster
    Explanation
    Resistance gene detection is a beneficial approach over AST (antibiotic susceptibility testing) because it provides a much faster result. This means that the resistance gene detection method can quickly identify whether a particular bacteria has acquired genes that make it resistant to antibiotics. In contrast, AST relies on the growth of the organism in culture, which takes longer to obtain results. Therefore, the speed of resistance gene detection allows for prompt decision-making in terms of selecting the appropriate antibiotic treatment, leading to more efficient and effective patient care.

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  • 5. 

    Antimicrobial Stewardship programs are designed to do all of the following, except:

    • Reduce the cost of health care for infections

    • Increase natural selection of antimicrobial resistance

    • Promote optimal drug selection

    • Support de-escalation of antimicrobials when appropriate

    Correct Answer
    A. Increase natural selection of antimicrobial resistance
    Explanation
    Antimicrobial Stewardship programs are designed to reduce the emergence and spread of antimicrobial resistance, not increase it. These programs aim to promote the appropriate and responsible use of antimicrobial drugs, ensuring that they are used only when necessary and that the most effective drug is selected. They also support the de-escalation of antimicrobial therapy when appropriate, meaning that the treatment is adjusted or stopped if the infection is under control. Additionally, these programs can help in reducing the overall cost of healthcare by preventing unnecessary antibiotic prescriptions and hospital admissions.

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  • 6. 

    What are outcomes of the recent Verigene BC-GP study publication covered in this training?

    • Increased length of stay with BC-GP

    • Decreased overall hospital costs with BC-GP

    • Significantly lower mortality with BC-GP

    • Increased duration of antibiotics use with BC-GP

    Correct Answer
    A. Decreased overall hospital costs with BC-GP
    Explanation
    The Verigene BC-GP study publication covered in this training shows that there is a decrease in overall hospital costs with BC-GP. This means that implementing the Verigene BC-GP system in hospitals can lead to cost savings for the healthcare facility.

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  • 7. 

    All of the following technologies have Antibiotic Susceptibility Testing (AST) capabilities, except:

    • Cepheid GeneXpert

    • BD Phoenix

    • BioMerieux Vitek 2

    • BioMerieux Vitek MS MALDI-TOF

    Correct Answer
    A. Cepheid GeneXpert
    Explanation
    The Cepheid GeneXpert is the only technology listed that does not have Antibiotic Susceptibility Testing (AST) capabilities. The BD Phoenix, bioMerieux Vitek 2, and bioMerieux Vitek MS MALDI-TOF are all commonly used technologies for performing AST, which is a method used to determine the effectiveness of antibiotics against specific bacteria. The Cepheid GeneXpert, on the other hand, is a molecular diagnostic platform that is primarily used for the detection of specific pathogens or genetic mutations, rather than for AST.

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  • 8. 

    Biofire's mecA target includes the detection of the staphylococcal cassette mec junction.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Biofire's mecA target does not include the detection of the staphylococcal cassette mec junction.

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  • 9. 

    Bacteria that are susceptible to an antibiotic are not inhibited by the usual concentrations of the antimicrobial agent.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    This statement is false. Bacteria that are susceptible to an antibiotic are indeed inhibited by the usual concentrations of the antimicrobial agent. When a bacteria is susceptible, it means that the antibiotic can effectively kill or inhibit its growth. Therefore, the usual concentrations of the antibiotic will be effective in inhibiting the susceptible bacteria.

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  • 10. 

    Which of the following are gram-negative resistance marker(s) found on current molecular panels?

    • MecA

    • IMP

    • OZO

    • CTX-M

    • B and d only

    Correct Answer
    A. B and d only
    Explanation
    The gram-negative resistance markers found on current molecular panels are IMP and CTX-M. mecA and OZO are not gram-negative resistance markers. Therefore, the correct answer is b and d only.

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  • 11. 

    Which of the following bacteria is commonly found to be resistant to antibiotics?

    • Staphylococcus

    • Klebsiella

    • Enterococcus faecium

    • Only a and b

    • All of the above

    Correct Answer
    A. All of the above
    Explanation
    All of the above bacteria are commonly found to be resistant to antibiotics. Staphylococcus, Klebsiella, and Enterococcus faecium are known to possess antibiotic resistance mechanisms that allow them to survive and multiply in the presence of antibiotics. This resistance can make infections caused by these bacteria difficult to treat and may require the use of alternative or stronger antibiotics.

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  • 12. 

    Which of the following are gram-positive resistance marker(s) found on current molecular panels?

    • KPC

    • MecD

    • VanA/vanB

    • A and b

    • All of the Above

    Correct Answer
    A. VanA/vanB
    Explanation
    The gram-positive resistance markers vanA/vanB are found on current molecular panels. These markers are associated with vancomycin resistance in gram-positive bacteria. The mecD marker is not a gram-positive resistance marker, and KPC is associated with carbapenem resistance in gram-negative bacteria. Therefore, the correct answer is "a and b" because vanA/vanB are gram-positive resistance markers found on current molecular panels.

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Quiz Review Timeline (Updated): Mar 17, 2023 +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Mar 17, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Apr 08, 2015
    Quiz Created by
    Nicole Siska

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