Pediatric Neurology Quiz: Test!

Cladribine is a medication that acts as an immunomodulator, meaning it helps to regulate the immune system. It has been shown to reduce relapses by 58% in patients with multiple sclerosis, a chronic autoimmune disease. Additionally, cladribine has activity against CD4 T, CD8 T, and CD19 B cells, which are all types of immune cells involved in the inflammatory response. Therefore, the correct answer is "All of the above."

The McDonald criteria are a set of guidelines used for the diagnosis of multiple sclerosis. These criteria help physicians determine if a patient's symptoms and clinical findings are consistent with multiple sclerosis. They take into account various factors such as the presence of characteristic lesions in the central nervous system, the pattern of symptom development, and the results of specific diagnostic tests like MRI and cerebrospinal fluid analysis. By applying these criteria, healthcare professionals can make a more accurate diagnosis of multiple sclerosis and initiate appropriate treatment.

It is X linked

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Thrombocytopenia is a relative contraindication

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It responds well to steroids

According to Sarnat and Sarnat stages of HIE, the status of oculovestibular reflex in stage 2 is "Over reactive". This means that the reflex is exaggerated or hypersensitive in this stage.

The correct answer is 10 mg/kg /dose 12 hourly. This dosage is recommended for chemoprophylaxis in all close contacts of meningococcal meningitis. It is important to administer the medication at a dose of 10 mg/kg and repeat it every 12 hours to ensure effective prevention of the disease. The other options of 5 mg/kg/dose 12 hourly, 5 mg/kg/day 24 hourly, and 10 mg/kg/day 24 hourly are not the recommended dosages for chemoprophylaxis in this scenario.

> 10 % of the eosinophils/ mm3 Atleast 10 % of leukocytes in CSF should be eosinioophils