Fluoroquinolones

10 Questions | By Raneem | Updated: Mar 18, 2022 | Attempts: 124

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1.

Fluoroquinolones are synthetic analogs of nalidixic acid
- A.
  
  True
- B.
  
  False
Correct Answer
A. True
2.

Norfloxacin :
- A.
  
  The least active against gram +ve & -ve bacteria
- B.
  
  Excellent grame -ve coverage & moderate gram +ve
- C.
  
  Improved gram +ve coverage
- D.
  
  None of the mentioned
Correct Answer
A. The least active against gram +ve & -ve bacteria
3.

Ciprofloxacin is the most active against gram +ve bacteria
- A.
  
  True
- B.
  
  False
Correct Answer
B. False
4.

Improved gram +ve coverage fluoroquinolones :
- A.
  
  Moxifloxacin
- B.
  
  Gemifloxacin
- C.
  
  Enoxacin
- D.
  
  C+B
- E.
  
  A+B
Correct Answer
E. A+B
5.

DNA gyrase is the primary drug target in gram +ve bacteria
- A.
  
  True
- B.
  
  False
Correct Answer
B. False
6.

One of the resistance mechanism of gram -ve bacteria to fluoroquinolones is reduction in porins protein
- A.
  
  True
- B.
  
  False
Correct Answer
A. True
7.

Clinical application of fluoroquinolones
- A.
  
  UTIs
- B.
  
  Bacterial diarrhea
- C.
  
  RTI
- D.
  
  All of the above
Correct Answer
D. All of the above
8.

Respiratory fluoroquinolones:
- A.
  
  Levofloxacin
- B.
  
  Ciprofloxacin
- C.
  
  Gemifloxacin
- D.
  
  A+B
- E.
  
  A+C
Correct Answer
E. A+C
9.

Ciprofloxacin is the drug of choice for prophylaxis and treatment of anthrax
- A.
  
  True
- B.
  
  False
Correct Answer
A. True
10.

One of the adverse reaction of fluoroquinolones is QTc prolongation so we should avoid use it with :
- A.
  
  Antiarrythmic drugs
- B.
  
  Sulfadoxine
- C.
  
  Rifampin
- D.
  
  A+B
Correct Answer
A. Antiarrythmic drugs

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Current Version
Mar 18, 2022

Quiz Edited by
ProProfs Editorial Team
Jan 04, 2019

Quiz Created by
Raneem

Fluoroquinolones

Fluoroquinolones are synthetic analogs of nalidixic acid

Norfloxacin :

Ciprofloxacin is the most active against gram +ve bacteria

Improved gram +ve coverage fluoroquinolones :

DNA gyrase is the primary drug target in gram +ve bacteria

One of the resistance mechanism of gram -ve bacteria to fluoroquinolones is reduction in porins protein

Clinical application of fluoroquinolones

Respiratory fluoroquinolones:

Ciprofloxacin is the drug of choice for prophylaxis and treatment of anthrax

One of the adverse reaction of fluoroquinolones is QTc prolongation so we should avoid use it with :