Fluoroquinolones

10 Questions | Total Attempts: 117

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Fluoroquinolones

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Questions and Answers
  • 1. 
    Fluoroquinolones are synthetic analogs of nalidixic acid 
    • A. 

      True

    • B. 

      False

  • 2. 
    Norfloxacin :
    • A. 

      The least active against gram +ve & -ve bacteria

    • B. 

      Excellent grame -ve coverage & moderate gram +ve 

    • C. 

      Improved gram +ve coverage 

    • D. 

      None of the mentioned 

  • 3. 
    Ciprofloxacin is the most active against gram +ve bacteria 
    • A. 

      True

    • B. 

      False

  • 4. 
    Improved gram +ve coverage fluoroquinolones :
    • A. 

      Moxifloxacin 

    • B. 

      Gemifloxacin 

    • C. 

      Enoxacin 

    • D. 

      C+B

    • E. 

      A+B

  • 5. 
    DNA gyrase is the primary drug target in gram +ve bacteria 
    • A. 

      True

    • B. 

      False

  • 6. 
    One of the resistance mechanism of gram -ve bacteria to fluoroquinolones is reduction in porins protein 
    • A. 

      True

    • B. 

      False

  • 7. 
    Clinical application of fluoroquinolones 
    • A. 

      UTIs 

    • B. 

      Bacterial diarrhea 

    • C. 

      RTI

    • D. 

      All of the above 

  • 8. 
    Respiratory fluoroquinolones: 
    • A. 

      Levofloxacin

    • B. 

      Ciprofloxacin

    • C. 

      Gemifloxacin

    • D. 

      A+B 

    • E. 

      A+C

  • 9. 
    Ciprofloxacin is the drug of choice for prophylaxis and treatment of anthrax
    • A. 

      True

    • B. 

      False

  • 10. 
    One of the adverse reaction of fluoroquinolones is QTc prolongation so we should avoid use it with : 
    • A. 

      Antiarrythmic drugs

    • B. 

      Sulfadoxine

    • C. 

      Rifampin 

    • D. 

      A+B