Learn Virology - Biology Of Virus Quiz

27 Questions | By Chinedua | Updated: Mar 21, 2022 | Attempts: 2258

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Learn Virology - Biology Of Virus Quiz - Quiz

Virology is the scientific field that deals with the study of viruses and viral diseases, which includes the distribution, biochemistry, physiology, molecular biology, ecology, and clinical aspects of viruses. Learn some new things about Virology in this biology quiz

Questions and Answers

1.

Which best describes viruses?
- A.
  
  Facultative intracellular parasites
- B.
  
  Protein core surrounded by nucleic acid
- C.
  
  Contain double or single stranded RNA or DNA
- D.
  
  Main opposition from humoral immunity
2.

Which of the following describes viruses but not bacteria?
- A.
  
  Undergo binary fission
- B.
  
  Relatively large in size
- C.
  
  Replicates with host mechanism
- D.
  
  Can replicate without host
3.

Which is true about Capsids of viruses
- A.
  
  Carries the genetic material
- B.
  
  Self assembles
- C.
  
  Icosahedral form has variable size
- D.
  
  Helical form has a defined set of subunits
- E.
  
  C & D
4.

Virus spikes are commonly associated with which of the following?
- A.
  
  Non enveloped viruses
- B.
  
  Glycoproteins
- C.
  
  Lipids from the host cell membrane
- D.
  
  Inability to cause hemaglutination
5.

Which of the following describes the adsorption of nonenveloped viruses
- A.
  
  Use glycoproteins
- B.
  
  Type III secretion system
- C.
  
  Can only attach to specific sites
- D.
  
  Exposed regions of capsid proteins
6.

Which of the following is true about translocation of non enveloped viruses?
- A.
  
  Occurs only at specific sites
- B.
  
  Uses clathrin coated puts
- C.
  
  Endocytosed into cell
- D.
  
  Freely crosses plasma membrane
7.

Which of the following virus types has nucleic acid that functions directly as mRNA?
- A.
  
  Single stranded positive sense RNA viruses
- B.
  
  Double stranded RNA viruses
- C.
  
  Single stranded negative sense viruses
- D.
  
  DNA viruses
8.

Which of the following uses genome as a template to make mRNA transcripts corresponding to each viral gene?
- A.
  
  Single stranded positive sense RNA viruses
- B.
  
  Single stranded negative sens RNA viruses
- C.
  
  Double stranded RNA viruses
- D.
  
  DNA viruses
9.

Which of the following viruses has information that must be copied into positive sense single strand of RNA
- A.
  
  Reoviridae
- B.
  
  Parvovirdae
- C.
  
  Polyomaviridae
- D.
  
  Picornaviridae
10.

Which of the following descriptions fit a virus that replicates through a DNA intermediate?
- A.
  
  Positive sense RNA used as a template and then DNA incorporated into Host
- B.
  
  Nucleic acid of the virion functions directly as mRNA
- C.
  
  Needs to use RNA dependent RNA polymerase
- D.
  
  A & C
11.

DNA viruses are best linked to which of the following?
- A.
  
  Nucleic acid acts directly as mRNA
- B.
  
  Flaviviridae
- C.
  
  Picornaviridae
- D.
  
  Transcription in host nucleus
12.

Release of nonenveloped viruses is best described by which of the following?
- A.
  
  Released by budding
- B.
  
  Released on cell lysis
- C.
  
  Disrupt cell membrane and bind to m proteins
- D.
  
  A & C
13.

Program cell death induced by some viruses during release has an antiviral effect
- A.
  
  True
- B.
  
  False
14.

A defective virus is a virus that
- A.
  
  Attacks the wrong site
- B.
  
  Cause cell death upon lysis
- C.
  
  Needs simultaneous infection
- D.
  
  Contain infectious proteins but no nucleic acid
15.

Prions are best described as which of the following?
- A.
  
  Cannot replicate without a helper virus
- B.
  
  Contain nucleic acid surrounded by infectious protein capsid
- C.
  
  Susceptible to proteolytic enzymes
- D.
  
  Proteins similar to that of normal cell
16.

Which of the following is likely to accumulate in the brain and spinal cord?
- A.
  
  Defective virus
- B.
  
  DNA virus
- C.
  
  Prion
- D.
  
  Non enveloped virus
17.

Which of the following occurs in the acute phase of viral infection but not in the latent phase?
- A.
  
  Infection by DNA viruses of retroviruses
- B.
  
  No production of progeny
- C.
  
  Reactivation or transformation
- D.
  
  Multiple rounds of replication
18.

Which of the following describes the chronic phase of viral infection?
- A.
  
  Caused by DNA viruses
- B.
  
  Caused by RNA viruses
- C.
  
  Affects competent immune systems
- D.
  
  Viral particles are not present
19.

Which of the following is true about enteroviruses?
- A.
  
  Entry replication and tissue tropism are at the same site
- B.
  
  Enter at one site and cause disease then spread
- C.
  
  Causes equal symptoms in children and adults
- D.
  
  None of the above
20.

During hematogenous spread which of the following is true?
- A.
  
  Bacteria spread through blood then replicate
- B.
  
  Can be asymtomatic
- C.
  
  Never have prodromal symptoms
- D.
  
  B & C
21.

A 40 y/o pt presents with viral infection, he has weakened cellular immunity, low antibody titers , functional interferons and a defective complement system. Which of these conditions will make elimination of his infection the most difficult?
- A.
  
  Weakened CMI
- B.
  
  Defective complement
- C.
  
  Low antibody response
- D.
  
  Age
22.

Which of the following inhibits early steps of viral replication and helps to prevent reinfection?
- A.
  
  CMI
- B.
  
  Antibody response
- C.
  
  Interferons
- D.
  
  None of the above
23.

Interferons are best described by which of the following?
- A.
  
  Beta interferons produced by leukocytes
- B.
  
  Induced by viruses only
- C.
  
  Inhibit protein synthesis mechanisms
- D.
  
  Gamma interferon is induced by fibroblasts and T cells
24.

Vaccination of children may result in which of the following disease causing conditions?
- A.
  
  Decreased antibody response
- B.
  
  Viral evasion of the immune system
- C.
  
  Virus induced immunopathology
- D.
  
  Weakened CMI
25.

Which of the following methods of virus DX, relies on comparison of acute phase and covalescent phases titers?
- A.
  
  Clinical presentation
- B.
  
  Tissue cultures
- C.
  
  Immunocytochemical staining of cell cultures
- D.
  
  Serological studies