Mic 541 Exam 4 - Virology - Part 1
Covers the first 100 powerpoint slides from the virology lectures for Micro exam #4.
- 1.What is a virion?
- A.
Nucleic acid and surrounding protein shell.
- B.
Major protein component of the shell of the core.
- C.
Single virus particle.
- D.
Membrane surrounding virus core.
- 2.What is the core?
- A.
Nucleic acid and surrounding protein shell.
- B.
Major protein component of the shell of the core.
- C.
Single virus particle.
- D.
Membrane surrounding virus core.
- 3.What is a capsid?
- A.
Nucleic acid and surrounding protein shell.
- B.
Single virus particle.
- C.
Major protein component of the shell of the core.
- D.
Membrane surrounding virus core.
- 4.What is the envelope?
- A.
Nucleic acid and surrounding protein shell.
- B.
Major protein component of the shell of the core.
- C.
Single virus particle.
- D.
Membrane surrounding virus core.
- 5.Viruses can survive outside of the cell.
- A.
True
- B.
False
- 6.Which of the following is (are) true concerning viruses?
- A.
May contain DNA as the genetic material.
- B.
May contain RNA as the genetic material.
- C.
Protein shell has an envelope.
- D.
Protein shell does not have an envelope.
- E.
They are the smallest of all self-replicating organisms.
- 7.Viruses can use which of the following as hosts?
- A.
Bacteria
- B.
Food
- C.
Protozoa
- D.
Plants
- E.
Animals
- F.
Algae
- G.
Fungi
- H.
Molds
- 8.Viruses can replicate in the:
- A.
Cytoplasm
- B.
Nucleus
- C.
Both cytoplasm and nucleus.
- 9.Viruses can result in acute death of the host.
- A.
True
- B.
False
- 10.Match the following terms with the definitions below: Host Range, Susceptibility.1. The capacity of a cell, tissue, or species to support virus replication - qualitatative measurement - number of receptor molecules and ability of host cell to support virus replciation.2. The cells, tissues, species that a virus can productively infect - absolute measurement - determined by receptor availability for virus binding/entry and presence of intracellular cell factors to support virus replication.
- A.
Host Range = 1, Susceptibility = 2.
- B.
Susceptibility = 1, Host Range = 2.
- C.
The definitions provided do not match the terms given.
- 11.The capsid provides protection against:
- A.
Variations in light.
- B.
Variations in pH.
- C.
Variations in temperature.
- D.
Chemicial composition of the environment.
- E.
Antibody binding.
- 12.The virus' structure is a:
- A.
Dodecahedron.
- B.
Icosahedron.
- C.
Square.
- D.
Tetrakaidecagon.
- E.
Tetradecagon.
- 13.The viral envelope can protect against:
- A.
Chemicals.
- B.
Changes in pH.
- C.
Changes in temperature.
- D.
Changes in light.
- E.
Enzymes.
- 14.How do most viruses acquire membranes/envelopes?
- A.
By the host cell phagocytizing the virus.
- B.
By generating it themselves.
- C.
Through glycosylation.
- D.
By budding through a host cell membrane.
- 15.Which of the following is true regarding virus binding?
- A.
Requires specific protein receptors.
- B.
Requires specific lipids.
- C.
Requires specific carbohydrates.
- D.
Requires specific vitamins.
- E.
May limit host-cell range AND susceptibility.
- F.
May limit host-cell range but NOT susceptibility.
- 16.Which type of virus fusion/entry is defined as: internalized into endosome - pH changes causes conformation change in envelope proetin and fusion with endosomal membrane and release into cytosol?
- 17.What are the possible mechanisms for virus fusion/entry into the host cell?
- A.
Phagocytosis.
- B.
Endocytosis.
- C.
Fusion with nuclear membrane.
- D.
Penetration through plasma membrane.
- E.
Fusion with plasma membrane.
- 18.Enveloped viruses may enter the host cell through:
- A.
Fusion with plasma membrane.
- B.
Penetration through plasma membrane.
- 19.Non-enveloped viruses may enter the host cell through:
- A.
Fusion with plasma membrane.
- B.
Penetration through plasma membrane.
- 20.Replication of RNA viruses typically occurs in the:
- A.
Nucleus
- B.
Golgi
- C.
ER
- D.
Cytoplasm
- 21.What enzyme is used in the replication of progeny genomic RNA molecules?
- A.
Viral specific RNA ligase
- B.
Viral specific RNA polymerase
- C.
Bacterial specific RNA polymerase
- D.
Bacterial specific DNA ligase
- 22.Replication of DNA viruses typically occurs in the:
- A.
Golgi
- B.
Cytoplasm
- C.
Nucles
- D.
ER
- 23.For enveloped viruses, assembly typically occurs at the site of replication.
- A.
True
- B.
False
- 24.What are the ways the virus undergoes budding/release?
- A.
Lysis.
- B.
Endocytosis.
- C.
Budding out of plasma membrane.
- D.
Fusion with nuclear membrane.
- E.
Exocytosis.
- 25.The majority of viruses are life-threatening.
- A.
True
- B.
False
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