Leukemias And Lymphomas

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Quizzes Created: 15 | Total Attempts: 36,806
Questions: 23 | Attempts: 7,677

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Leukemias And Lymphomas - Quiz


Questions and Answers
  • 1. 

    Commonly presents with Fever, Bone pain, Lymphadenopathy (non-tender, firm, rubbery), Bleeding, Abnormal testicular enlargement, and/or Mediastinal Mass

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    B. ALL (Acute Lymphocytic Leukemia)
    Explanation
    The given symptoms, such as fever, bone pain, lymphadenopathy, bleeding, abnormal testicular enlargement, and mediastinal mass, are commonly associated with ALL (Acute Lymphocytic Leukemia). AML (Acute Myelogenous Leukemia) may present with similar symptoms, but the presence of a mediastinal mass is more indicative of ALL. CLL (Chronic Lymphocytic Leukemia) and CML (Chronic Myelogenous Leukemia) typically have a more indolent course and do not commonly present with these specific symptoms.

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  • 2. 

    Most common form of cancer in children

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    B. ALL (Acute Lymphocytic Leukemia)
    Explanation
    ALL (Acute Lymphocytic Leukemia) is the most common form of cancer in children. Leukemia is a type of cancer that affects the bone marrow and blood. ALL specifically affects the lymphoid cells, which are responsible for producing white blood cells. It is more commonly diagnosed in children between the ages of 2 and 5. The exact cause of ALL is unknown, but it is believed to involve a combination of genetic and environmental factors. Treatment for ALL typically involves chemotherapy, radiation therapy, and sometimes stem cell transplantation.

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  • 3. 

    Uncertain etiology, but several proposed linkages such as: Genetic - Philadelphia chromosome, Viral infection (EBV, HIV), Exposure to high energy radiation (T-cell ALL),Toxic chemical exposure, Smoking

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    B. ALL (Acute Lymphocytic Leukemia)
    Explanation
    The given answer is ALL (Acute Lymphocytic Leukemia). The explanation for this is that the question mentions several proposed linkages for the uncertain etiology of leukemia, such as genetic factors like the Philadelphia chromosome, viral infections like EBV and HIV, exposure to high energy radiation (which is specifically linked to T-cell ALL), toxic chemical exposure, and smoking. Among the given options, ALL is the type of leukemia that is commonly associated with these proposed linkages, making it the correct answer.

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  • 4. 

    Seen in Men > Women, median age >70

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    C. CLL (Chronic Lymphocytic Leukemia)
    Explanation
    The correct answer is CLL (Chronic Lymphocytic Leukemia) because it is the only type of leukemia listed that typically affects older individuals, which is indicated by the statement "Seen in Men > Women, median age >70". AML, ALL, and CML can occur at any age, but CLL is more commonly diagnosed in individuals over the age of 70.

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  • 5. 

    Progressive accumulation of functionally incompetent lymphocytes.

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    C. CLL (Chronic Lymphocytic Leukemia)
    Explanation
    Chronic Lymphocytic Leukemia (CLL) is characterized by the progressive accumulation of functionally incompetent lymphocytes. In CLL, there is an overproduction of abnormal lymphocytes that are unable to effectively fight off infections. These dysfunctional lymphocytes accumulate in the bone marrow, blood, and lymph nodes, leading to the characteristic symptoms of CLL such as fatigue, enlarged lymph nodes, and increased susceptibility to infections. AML, ALL, and CML are different types of leukemia that do not specifically involve the progressive accumulation of functionally incompetent lymphocytes.

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  • 6. 

    Clinical presentation of painless, swelling of lymph nodes, lymphocytosis upon CBC, Splenomegaly, Hepatomegaly, AI Thrombocytopenia, hemolytic anemia, and/or Hypogammaglobulinemia

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CML (Chronic Myelogenous Leukemia)

    • D.

      CLL (Chronic Lymphocytic Leukemia)

    Correct Answer
    D. CLL (Chronic Lymphocytic Leukemia)
    Explanation
    The clinical presentation described in the question is consistent with Chronic Lymphocytic Leukemia (CLL). CLL is characterized by painless swelling of lymph nodes, lymphocytosis (increased number of lymphocytes) on complete blood count (CBC), splenomegaly (enlarged spleen), hepatomegaly (enlarged liver), AI thrombocytopenia (autoimmune destruction of platelets), hemolytic anemia (destruction of red blood cells), and/or hypogammaglobulinemia (low levels of antibodies). AML, ALL, and CML do not typically present with these specific symptoms.

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  • 7. 

    Most cases > 60 years old. Most common leukemia in adults

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    A. AML (Acute Myelogenous Leukemia)
    Explanation
    AML (Acute Myelogenous Leukemia) is the most common leukemia in adults. It primarily affects individuals who are over 60 years old. AML is a type of cancer that starts in the bone marrow and affects the production of normal blood cells. It is characterized by the rapid growth of abnormal myeloid cells, which are a type of white blood cell. The symptoms of AML can include fatigue, shortness of breath, easy bruising or bleeding, and frequent infections. Treatment for AML may involve chemotherapy, radiation therapy, and stem cell transplantation.

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  • 8. 

    Very poor prognosis. Fatal if untreated or if mismanaged in first few days

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    A. AML (Acute Myelogenous Leukemia)
    Explanation
    AML (Acute Myelogenous Leukemia) has a very poor prognosis and can be fatal if left untreated or mismanaged in the first few days. This means that if AML is not diagnosed and treated promptly, it can lead to serious complications and even death. The other types of leukemia listed (ALL, CLL, and CML) may also have poor prognoses, but the given statement specifically mentions AML as the correct answer.

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  • 9. 

    Characterized by: Pancytopenia, Hemmorhagic Findings, Easy Fatigue and weakness, Gingival hyperplasia. Fever in the presence of infection only, and/or Luekemic cutis (skin involvement)

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    A. AML (Acute Myelogenous Leukemia)
    Explanation
    The given symptoms, including pancytopenia, hemorrhagic findings, easy fatigue and weakness, gingival hyperplasia, fever in the presence of infection only, and/or leukemic cutis (skin involvement), are characteristic of Acute Myelogenous Leukemia (AML). AML is a type of leukemia that affects the myeloid cells in the bone marrow, leading to a decrease in the production of red blood cells, white blood cells, and platelets. The symptoms mentioned are commonly seen in AML patients due to the disruption of normal blood cell production and function.

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  • 10. 

    Characterized by chromosomal aberrations such as: –Deletions –Polyploidy –Translocations –Hyperploidy –Inversions 

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    A. AML (Acute Myelogenous Leukemia)
    Explanation
    AML is characterized by chromosomal aberrations such as deletions, polyploidy, translocations, hyperploidy, and inversions. This means that individuals with AML may have abnormalities in their chromosomes, such as missing or extra genetic material, rearrangements of genetic material between chromosomes, or changes in the overall number of chromosomes. These chromosomal aberrations play a role in the development and progression of AML.

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  • 11. 

    Median age is 50 years old with male predominance

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    D. CML (Chronic Myelogenous Leukemia)
    Explanation
    The correct answer is CML (Chronic Myelogenous Leukemia) because it is the only type of leukemia among the given options that typically occurs in older adults. The median age of diagnosis for CML is around 50 years old, and it is also more common in males. AML and ALL are more commonly diagnosed in children and younger adults, while CLL is usually diagnosed in older adults but does not have a male predominance.

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  • 12. 

    C—onverts to acute leukemia (blast crisis) if treatment is not successful

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    D. CML (Chronic Myelogenous Leukemia)
    Explanation
    Chronic Myelogenous Leukemia (CML) converts to acute leukemia (blast crisis) if treatment is not successful. This means that if the initial treatment for CML is not effective, it can progress to a more aggressive form of leukemia known as blast crisis. This is an important consideration in the management and treatment of CML, as it highlights the need for early and effective interventions to prevent disease progression.

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  • 13. 

    Characterized by easy fatigability, malaise, anorexia, early satiety, excessive sweating, weight loss, and upon PE, splenomegaly, pallor,  and sternal tenderness

    • A.

      AML (Acute Myelogenous Leukemia)

    • B.

      ALL (Acute Lymphocytic Leukemia)

    • C.

      CLL (Chronic Lymphocytic Leukemia)

    • D.

      CML (Chronic Myelogenous Leukemia)

    Correct Answer
    D. CML (Chronic Myelogenous Leukemia)
    Explanation
    The given symptoms, including easy fatigability, malaise, anorexia, early satiety, excessive sweating, weight loss, splenomegaly, pallor, and sternal tenderness, are characteristic of Chronic Myelogenous Leukemia (CML). CML is a type of leukemia that affects the myeloid cells in the bone marrow, leading to an overproduction of abnormal white blood cells. These symptoms are commonly seen in CML patients due to the disruption of normal blood cell production and the infiltration of leukemic cells into various organs, such as the spleen. Therefore, CML is the most appropriate answer based on the given information.

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  • 14. 

    Fight viral infections

    • A.

      T-Cell

    • B.

      B-Cell

    Correct Answer
    A. T-Cell
    Explanation
    T-cells are a type of white blood cell that play a crucial role in the immune response against viral infections. They are responsible for recognizing infected cells and destroying them, thus preventing the spread of the virus. B-cells, on the other hand, are involved in producing antibodies that can neutralize viruses and prevent them from infecting healthy cells. However, T-cells are specifically known for their direct involvement in fighting viral infections, making them the correct answer in this context.

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  • 15. 

    Make Antibodies

    • A.

      T-Cell

    • B.

      B-Cell

    Correct Answer
    B. B-Cell
    Explanation
    B-Cells are responsible for producing antibodies, which are proteins that help the immune system fight off infections. When a B-Cell encounters an antigen (a foreign substance), it binds to it and starts producing antibodies specific to that antigen. These antibodies then attach to the antigen, marking it for destruction by other immune cells or neutralizing its harmful effects. Therefore, B-Cells play a crucial role in the adaptive immune response by generating a specific immune response against pathogens. T-Cells, on the other hand, have different functions such as recognizing infected cells and directly killing them.

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  • 16. 

    Which type of cell is most directly associated with lymph nodes and the spleen?

    • A.

      T-Cell

    • B.

      B-Cell

    Correct Answer
    B. B-Cell
    Explanation
    B-cells are a type of white blood cell that plays a crucial role in the immune response. They are responsible for producing antibodies, which are proteins that can recognize and bind to specific pathogens or foreign substances in the body. This binding helps to mark the pathogens for destruction by other immune cells. Lymph nodes and the spleen are important locations where B-cells are produced, matured, and activated to carry out their immune functions. Therefore, the presence of B-cells in lymph nodes and the spleen supports the given answer.

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  • 17. 

    Matures in thymus

    • A.

      T-Cell

    • B.

      B-Cell

    Correct Answer
    A. T-Cell
    Explanation
    T-Cells are a type of white blood cell that play a crucial role in the immune system. They are produced in the bone marrow and then mature in the thymus gland. The thymus is responsible for the development and maturation of T-cells, which are essential for recognizing and attacking foreign pathogens in the body. Therefore, the statement "Matures in thymus" correctly describes the maturation process of T-cells.

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  • 18. 

    Lymphoma arises in a single node or chain of nodes

    • A.

      Hodgkin's Lymphoma

    • B.

      Non-Hodgkin's Lymphoma

    Correct Answer
    A. Hodgkin's Lymphoma
    Explanation
    Hodgkin's Lymphoma is the correct answer because it is a type of lymphoma that typically arises in a single node or chain of nodes. Non-Hodgkin's Lymphoma, on the other hand, can arise in multiple nodes and is more diverse in terms of its presentation and behavior. Therefore, the fact that the lymphoma arises in a single node or chain of nodes is characteristic of Hodgkin's Lymphoma.

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  • 19. 

    Reed-Sternberg cells are present

    • A.

      Hodgkin's Lymphoma

    • B.

      Non-Hodgkin's Lymphoma

    Correct Answer
    A. Hodgkin's Lymphoma
    Explanation
    The presence of Reed-Sternberg cells is a characteristic feature of Hodgkin's lymphoma. These abnormal cells are large, multinucleated cells that are found in the lymph nodes affected by Hodgkin's lymphoma. Non-Hodgkin's lymphoma, on the other hand, does not typically present with Reed-Sternberg cells. Therefore, the presence of these cells indicates a diagnosis of Hodgkin's lymphoma rather than non-Hodgkin's lymphoma.

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  • 20. 

    Lymphoma originates at extranodal sites and spreads to anatomically contiguous nodes

    • A.

      Hodgkin's Lymphoma

    • B.

      Non-Hodgkin's Lymphoma

    Correct Answer
    B. Non-Hodgkin's Lymphoma
    Explanation
    Non-Hodgkin's Lymphoma is the correct answer because it is a type of lymphoma that originates at extranodal sites, such as the gastrointestinal tract, skin, or lungs, and then spreads to anatomically contiguous lymph nodes. In contrast, Hodgkin's Lymphoma typically starts in a single lymph node and spreads in a more predictable manner through the lymphatic system.

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  • 21. 

    Reed-Sternberg cells are not present

    • A.

      Hodgkin's Lymphoma

    • B.

      Non-Hodgkin's Lymphoma

    Correct Answer
    B. Non-Hodgkin's Lymphoma
    Explanation
    The absence of Reed-Sternberg cells indicates that the patient is not suffering from Hodgkin's Lymphoma. Reed-Sternberg cells are large abnormal cells that are characteristic of Hodgkin's Lymphoma. Therefore, the correct answer is Non-Hodgkin's Lymphoma, which is a group of lymphomas that do not involve Reed-Sternberg cells.

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  • 22. 

    Humoral immunity

    • A.

      B-cells

    • B.

      T-cells

    Correct Answer
    A. B-cells
    Explanation
    B-cells are a type of white blood cell that play a crucial role in humoral immunity. Humoral immunity is a branch of the immune system that involves the production of antibodies by B-cells. These antibodies help to neutralize and eliminate pathogens, such as bacteria and viruses, from the body. B-cells are responsible for recognizing specific antigens on the surface of pathogens and producing antibodies that are able to bind to these antigens. This immune response is important for protecting the body against infections and diseases. T-cells, on the other hand, are involved in cell-mediated immunity, which is a different branch of the immune system.

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  • 23. 

    Cellular immunity

    • A.

      B-cells

    • B.

      T-cells

    Correct Answer
    B. T-cells
    Explanation
    T-cells are a type of white blood cell that plays a crucial role in cellular immunity. They are responsible for recognizing and attacking infected cells, cancer cells, and foreign substances in the body. T-cells are able to distinguish between healthy and infected cells by recognizing specific antigens on the surface of the cells. Once activated, they can directly kill the infected cells or release chemical signals to recruit other immune cells to the site of infection. B-cells, on the other hand, are responsible for producing antibodies that target pathogens outside of cells.

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Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • May 09, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Mar 03, 2012
    Quiz Created by
    Bikisoucy

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