The Toughest Histology MCQ Test!

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  • 1/460 Questions

    Which organelle is considered the powerhouse of the cell?

    • Rough endoplasmic reticulum
    • Smooth endoplasmic reticulum
    • Lysosome
    • Golgi apparatus
    • Mitochondria
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About This Quiz

Are you studying to become a lab technician? One of the things that will be expected of you is a good understanding when it comes to histology, and below is what is considered the toughest MCQ test on the course. Think you have what it takes to handle it? Well take up the quiz below and see just how well See moreyou will do.

The Toughest Histology MCQ Test! - Quiz

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  • 2. 

    How many types of cartilage are there?

    • 1

    • 2

    • 3

    • 4

    • 5

    Correct Answer
    A. 3
    Explanation
    There are three types of cartilage: hyaline cartilage, elastic cartilage and fibrocartilage.

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  • 3. 

    Which of the following is composed of cardiac muscle?

    • Biceps muscle

    • Tongue

    • Heart

    • Upper esophagus

    • Walls of the visceral organs

    Correct Answer
    A. Heart
    Explanation
    The heart is composed of cardiac muscle.

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  • 4. 

    What are the gaps that occur within the myelin sheath?

    • Meninges

    • Myelinated nerve fibers

    • Cell bodies

    • Nodes of Ranvier

    • Neurofilaments

    Correct Answer
    A. Nodes of Ranvier
    Explanation
    A ganglion is a collection of nerve cell bodies outside of the central nervous system. White matter is myelinated nerve fibers. Gray matter is essentially neuron cell bodies. Nodes of Ranvier are the gaps that occur in the myelin sheath. Neurofilaments are a type of intermediate filaments seen in neurons.

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  • 5. 

    What is another term for the cell body of a neuron?

    • Tracts

    • Islets

    • Soma

    • Cortex

    • Nuclei

    Correct Answer
    A. Soma
    Explanation
    A group of fibers traveling together to a destination is a tract. Islets of Langerhans are seen in the pancreas. Soma is another term for a neuron cell body. The outer part of the brain is gray matter called the cortex. The conglomerations of gray matter deep within the cerebrum and cerebellum are called nuclei.

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  • 6. 

    Which type of microscope has only one lens?

    • Simple microscope

    • Compound microscope

    • Phase contrast microscope

    • Dissection microscope

    • Transmission electron microscope

    Correct Answer
    A. Simple microscope
    Explanation
    A simple microscope has only one lens. A compound microscope utilizes two lenses: an ocular lens and an objective lens. The compound microscope is also referred to as a "light microscope" or "bright field microscope". A phase contrast microscope is useful for examining living cells, because the specimen does not need to be stained. A dissection microscope uses low power magnification. Things appear three dimensional with a dissection microscope. A transmission electron microscope does not use light, but rather a beam of electrons.

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  • 7. 

    Which of the following is an organelle?

    • Pigment

    • Glycogen

    • Lipid

    • Secretory granules

    • Mitochondria

    Correct Answer
    A. Mitochondria
    Explanation
    Mitochondria is an organelle. Pigment, glycogen, lipid, and secretory granules are all considered inclusions. Organelles perform an activity; they have a job; they require energy. Inclusions are for storage. Inclusions do not perform an energy requiring job.

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  • 8. 

    Which type of cartilage is characterized by the presence of elastic fibers?

    • Hyaline cartilage

    • Elastic cartilage

    • Fibrocartilage

    • All of the above

    • None of the above

    Correct Answer
    A. Elastic cartilage
    Explanation
    Elastic cartilage has elastic fibers in the matrix.

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  • 9. 

    Which organelle contains digestive enzymes?

    • Rough endoplasmic reticulum

    • Smooth endoplasmic reticulum

    • Lysosome

    • Golgi apparatus

    • Mitochondria

    Correct Answer
    A. Lysosome
    Explanation
    Lysosomes are membrane bound sacs of digestive enzymes. They are nicknamed "suicide sacs".

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  • 10. 

    What are the folds on the inner mitochodrial membrane called?

    • Plasmalemma

    • Glycocalyx

    • Protoplasm

    • Cristae

    • Ground substance

    Correct Answer
    A. Cristae
    Explanation
    The cell boundary is defined by the cell membrane or plasmalemma. Glycocalyx is a polysacchride that can be found on the outer surface of the cell membranes. Collectively, the cytoplasm and nucleus form the protoplasm of a cell. The folds on the inner mitochodrial membrane are called cristae. The cytoplasm that surrounds organelles is the cytoplasmic ground substance or cytosol.

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  • 11. 

    What is dense bone?

    • Immature bone

    • Cancellous bone

    • Compact bone

    • Woven bone

    • Spongy bone

    Correct Answer
    A. Compact bone
    Explanation
    Compact bone is also called dense bone. Compact bone has the Haversian system.

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  • 12. 

    Where is thick skin found?

    • Over the knee

    • Sole of the feet

    • Breast

    • Lips

    • All of the above

    Correct Answer
    A. Sole of the feet
    Explanation
    Thick skin is found on the sole of the feet. This area of the body is subjected to constant pressure and friction, which requires a thicker and more protective layer of skin. The thick skin on the sole of the feet helps to prevent damage and provides support for walking and standing.

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  • 13. 

    Where is the site of protein synthesis?

    • Ribosomes

    • Peroxisome

    • Microfilaments

    • Centrioles

    • Nucleoli

    Correct Answer
    A. Ribosomes
    Explanation
    The ribosomes are the site of protein synthesis.

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  • 14. 

    Where is cardiac muscle found?

    • Myofilaments

    • Myosin

    • Muscle fibers

    • Myofibrils

    • Myocardium

    Correct Answer
    A. Myocardium
    Explanation
    Myocardium is the muscular layer of the heart. Thus, the myocardium is composed of cardiac muscle.

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  • 15. 

    Which cell is responsible for skin pigmentation?

    • Langerhans cell

    • Keratinocyte

    • Melanocyte

    • Merkel cell

    • Fibroblast

    Correct Answer
    A. Melanocyte
    Explanation
    The melanocyte produces melanin, which is responsible for skin pigmentation.

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  • 16. 

    Which is the most abundant fiber in connective tissue?

    • Collagen fiber

    • Elastic fiber

    • Reticular fiber

    • Purkinje fiber

    • Muscle fibers

    Correct Answer
    A. Collagen fiber
    Explanation
    There are three types of fibers found in connective tissue: collagen fibers, elastic fibers, and reticular fibers. Collagen fibers are the most abundant fiber type in connective tissue.

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  • 17. 

    Which of the following stains is used for routine histological examination?

    • Wright's stain

    • Hematoxylin and eosin stain

    • Sudan stain

    • Silver impregnation

    • Masson's trichrome stain

    Correct Answer
    A. Hematoxylin and eosin stain
    Explanation
    A peripheral blood smear would be best visualized with Wright's stain. Hematoxylin and eosin stain is the most commonly used tissue stain for routine histological examination. Lipids are best displayed with a sudan stain. Silver impregnation, such as with a reticular stain, can be used to visualize reticular fibers. Collagen fibers can be differentiated from other fibers by staining with Masson's trichrome stain.

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  • 18. 

    What is a characteristic of the cells in the epidermis of the skin?

    • Microvilli

    • Stereocilia

    • Cilia

    • Keratinization

    • Both a and b

    Correct Answer
    A. Keratinization
    Explanation
    Keratinization is seen in the epidermis. Cells in the stratum corneum are essentially just bags of keratin.

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  • 19. 

    Which connective tissue cell type produces collagen?

    • Fibroblast

    • Connective tissue macrophage

    • Histiocyte

    • Plasma cell

    • Mast cell

    Correct Answer
    A. Fibroblast
    Explanation
    Fibroblasts produce collagen. The fibroblast also produces the ground substance in connective tissue.

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  • 20. 

    What is the light band in muscle?

    • A band

    • I band

    • Z line

    • H band

    • M line

    Correct Answer
    A. I band
    Explanation
    The A band is the darker staining band. The I band is the light band. The I band is made of thin filaments. The Z line runs through the I band. The H band bisects the A band. The M line runs through the H band.

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  • 21. 

    Where is the primary site for absorption of nutrients?

    • Stomach

    • Small intestine

    • Ascending colon

    • Descending colon

    • Stomach and Small intestine equally

    Correct Answer
    A. Small intestine
    Explanation
    The small intestine is the primary site for absorption of nutrients.

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  • 22. 

    What is the end of an axon called?

    • Ganglion

    • Perikaryon

    • Astrocyte

    • Nissl

    • Terminal bouton

    Correct Answer
    A. Terminal bouton
    Explanation
    A ganglion is a collection of neuron cell bodies outside of the central nervous system. The cell body of a neuron is called a perikaryon or soma. An astrocyte is a supporting cell seen in the central nervous system. The basophilic clusters of ribosomes and rough endoplasmic seen in neuron cell bodies is called Nissl, Nissl bodies or Nissl substance. The terminal bouton is the end portion of an axon. It is also called an axon terminal or end bulb. The terminal bouton will be associated with another neuron in a synapse.

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  • 23. 

    What process is nicknamed "cell drinking"?

    • Endocytosis

    • Exocytosis

    • Pinocytosis

    • Phagocytosis

    • Active transport

    Correct Answer
    A. Pinocytosis
    Explanation
    Pinocytosis is "cell drinking".

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  • 24. 

    Which of the following is NOT a function of skin?

    • Vitamin D production

    • Protection from water loss

    • Sensory reception

    • Heat regulation

    • All are functions of skin

    Correct Answer
    A. All are functions of skin
    Explanation
    The skin is involved in the production of vitamin D from precursors with the aid of the sun. It protects the body from water loss. There are many sensory receptors in the skin: pain, pressure, fine touch. The skin is also involved in heat regulation. In addition, the skin protects the body.

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  • 25. 

    What is a characteristic of the cells in the epidermis of the skin?

    • Microvilli

    • Stereocilia

    • Cilia

    • Keratinization

    • Microvilli and Stereocilia

    Correct Answer
    A. Keratinization
    Explanation
    Keratinization is seen in the epidermis. Cells in the stratum corneum are essentially just bags of keratin.

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  • 26. 

    Where do you place the slide when using a microscope?

    • Base

    • Nosepiece

    • Stage

    • Tube

    • Diaphragm

    Correct Answer
    A. Stage
    Explanation
    The base is the bottom of the microscope. The revolving nosepiece is also called a turret. The objective lens are attached to the nosepiece (or turret). The slide rests on the stage. The tube is the structure which connects the eyepiece to the objective lenses (it is shaped like a tube; thus, its name). The diaphragm controls the diameter of the cone of light.

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  • 27. 

    Which organelle is studded with ribosomes?

    • Rough endoplasmic reticulum

    • Smooth endoplasmic reticulum

    • Lysosome

    • Golgi apparatus

    • Mitochondria

    Correct Answer
    A. Rough endoplasmic reticulum
    Explanation
    Endoplasmic reticulum is a system of tubules. If there are ribosomes on the tubules, it is termed "rough endoplasmic reticulum". Ribosomes produce proteins. When the ribosomes are attached to endoplasmic reticulum, the proteins produced by the ribosomes are exported. If there are no ribosomes on the endoplasmic reticulum, it is called "smooth endoplasmic reticulum". The role of smooth endoplasmic reticulum is lipid metabolism.

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  • 28. 

    Which of the following is NOT a fiber found in connective tissue?

    • Collagen fiber

    • Elastic fiber

    • Reticular fiber

    • Purkinje fiber

    • All of the above are fibers found in connective tissue

    Correct Answer
    A. Purkinje fiber
    Explanation
    Purkinje fibers are seen in the heart. Purkinje fibers are specialized muscle fibers.

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  • 29. 

    What does connective tissue develop from?

    • Mesothelium

    • Mesenchyme

    • Mesangial cells

    • Mesentery

    • Wharton's jelly

    Correct Answer
    A. Mesenchyme
    Explanation
    Connective tissue develops from mesenchyme.

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  • 30. 

    What is the connective tissue covering which surrounds cartilage?

    • Perimysium

    • Periosteum

    • Perichondrium

    • Perineurium

    • Endosteum

    Correct Answer
    A. Perichondrium
    Explanation
    The perichondrium is the connective tissue which surrounds cartilage.

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  • 31. 

    What is the primary component of red marrow?

    • Hematopoietic tissue

    • Fat

    • Cartilage

    • Fibrous tissue

    • Bone

    Correct Answer
    A. Hematopoietic tissue
    Explanation
    Red marrow contains active hematopoietic tissue. Yellow marrow is primarily fat

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  • 32. 

    Which of the following would be best suited to visualize lipid?

    • Wright's stain

    • Hematoxylin and eosin stain

    • Sudan stain

    • Silver impregnation

    • Masson's trichrome stain

    Correct Answer
    A. Sudan stain
    Explanation
    Sudan stain would be best suited to visualize lipids because it is a specific stain that binds to lipids, making them visible under a microscope. This stain is commonly used in histology to identify and study lipid-rich tissues or structures, such as adipose tissue. It allows for the visualization and differentiation of lipids based on their color or intensity of staining, providing valuable information about their distribution and composition.

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  • 33. 

    What type of epithelium appears stratified, but is not?

    • Epithelioid tissue

    • Mesothelium

    • Endothelium

    • Transitional

    • Pseudostratified

    Correct Answer
    A. Pseudostratified
    Explanation
    Pseudostratified epithelium is a type of epithelium that has cells which all touch the basement membrane. Pseudostratified epithelium is only one cell layer thick. Pseudostratified epithelium appears stratified, but it is not really stratified. Thus the name. The prefix "pseudo" means false, such as pseudonym or pseudo-science.

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  • 34. 

    What type of gland secretes its product directly into the bloodstream?

    • Endocrine gland

    • Multicellular gland

    • Exocrine gland

    • All of the above

    • None of the above

    Correct Answer
    A. Endocrine gland
    Explanation
    An endocrine gland secretes its product directly into the bloodstream, without a duct or tube. An exocrine gland secretes its product through a duct or tube.

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  • 35. 

    What type of basic tissue type is bone?

    • Epithelium

    • Connective tissue

    • Muscle

    • Nervous

    • Bone

    Correct Answer
    A. Connective tissue
    Explanation
    Of the four basic tissue types (epithelium, connective tissue, muscle and nervous tissue), connective tissue is the most diverse. Bone is a type of connective tissue

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  • 36. 

    What is the mature bone cell called?

    • Osteoclast

    • Osteon

    • Osteocyte

    • Osteoblast

    • Osteoid

    Correct Answer
    A. Osteocyte
    Explanation
    The mature bone cell is called an osteocyte. It sits in a space, called a lacuna.

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  • 37. 

    Which of the following forms myelin in the peripheral nervous system?

    • Schwann cells

    • Basket cells

    • Ganglion

    • Neuroglia

    • Satellite cells

    Correct Answer
    A. Schwann cells
    Explanation
    Schwann cells are responsible for the myelination of neurons in the peripheral nervous system. Basket cells are a type of neuron seen in the cerebellum. A ganglion is a collection of nerve cell bodies outside of the CNS. Neuroglia are the supporting cells in the central nervous system Sometimes, neuroglia called glial cells or glia. Satellite cells are found in the ganglia of the peripheral nervous system.

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  • 38. 

    Which of the following is an element of the central nervous system?

    • Receptors

    • Brachial plexus

    • Brain

    • Ganglia

    • Sciatic nerve

    Correct Answer
    A. Brain
    Explanation
    The central nervous system consists of the brain and spinal cord. All other nervous system elements are considered to be in the peripheral nervous system. Thus the peripheral nervous system includes receptors, the brachial plexus, the sciatic nerve, and ganglia.

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  • 39. 

    What is the connective tissue covering around the brain and spinal cord?

    • Meninges

    • Myelinated nerve fibers

    • Cell bodies

    • Nodes of Ranvier

    • Neurofilaments

    Correct Answer
    A. Meninges
    Explanation
    A ganglion is a collection of nerve cell bodies outside of the central nervous system. White matter is myelinated nerve fibers. Gray matter is essentially neuron cell bodies. Nodes of Ranvier are the gaps that occur in the myelin sheath. Neurofilaments are a type of intermediate filaments seen in neurons.

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  • 40. 

    What is the cell body of a neuron called?

    • Ganglion

    • Soma

    • Astrocyte

    • Nissl

    • Terminal bouton

    Correct Answer
    A. Soma
    Explanation
    A ganglion is a collection of neuron cell bodies outside of the central nervous system. The cell body of a neuron is called a perikaryon or soma. An astrocyte is a supporting cell seen in the central nervous system. The basophilic clusters of ribosomes and rough endoplasmic seen in neuron cell bodies is called Nissl, Nissl bodies or Nissl substance. The terminal bouton is the end portion of an axon. It is also called an axon terminal or end bulb. The terminal bouton will be > associated with another neuron in a synapse.

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  • 41. 

    Which organelle contains detoxifying enzymes?

    • Ribosomes

    • Peroxisome

    • Microfilaments

    • Centrioles

    • Nucleoli

    Correct Answer
    A. Peroxisome
    Explanation
    Peroxisomes contain enzymes for detoxification. One of the enzymes within peroxisomes is catalase. Catalase is involved in the breakdown of hydrogen peroxide.

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  • 42. 

    Which of the following would be best suited to visualize lipid?

    • Wright's stain

    • Hematoxylin and eosin stain

    • Sudan stain

    • Silver impregnation

    • Masson's trichrome stain

    Correct Answer
    A. Sudan stain
    Explanation
    Lipids are best displayed with a sudan stain

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  • 43. 

    Which type of cartilage is found in the external ear?

    • Hyaline cartilage

    • Elastic cartilage

    • Fibrocartilage

    • All of the above

    • None of the above

    Correct Answer
    A. Elastic cartilage
    Explanation
    Elastic cartilage is found in the external ear.

    Note from Sarah Bellham: If you bend your ear forward, it bounces back into its proper position. This is due to the elastic cartilage.

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  • 44. 

    Regarding the blood supply to cartilage:

    • Cartilage has minimal circulation

    • Cartilage has a duel circulation

    • Cartilage is highly vascular

    • Cartilage is avascular

    • There is nothing unique about the blood supply to cartilage

    Correct Answer
    A. Cartilage is avascular
    Explanation
    Cartilage is avascular. Nutrients reach cartilage by diffusion from the adjacent tissues.

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  • 45. 

    What is compact bone?

    • Dense bone

    • Woven bone

    • Immature bone

    • Cancellous bone

    • Spongy bone

    Correct Answer
    A. Dense bone
    Explanation
    Compact bone is also called dense bone. Compact bone has the Haversian system.

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  • 46. 

    What is released at a synapse?

    • Motor unit

    • Motor neuron

    • Motor end plate

    • Neuromuscular spindle

    • Neurotransmitter

    Correct Answer
    A. Neurotransmitter
    Explanation
    A single motor neuron and the aggregation of muscle fibers innervated by that single neuron is called the motor unit. A motor neuron is a neuron which innervates a muscle cell. The point of contact where a neuron contacts a muscle is the motor end plate. A neuromuscular spindle is a receptor which is sensitive to stretching of the muscle. A neurotransmitter is the chemical released by a nerve at a synapse.

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  • 47. 

    Which cell is a hepatic macrophage?

    • Kupffer cells

    • Histiocyte

    • Dust cell

    • Langerhans cell

    • Microglia

    Correct Answer
    A. Kupffer cells
    Explanation
    Macrophages are mononuclear phagocytes. Many tissues have resident (fixed) macrophages. Fixed macrophages are given a unique name, depending on the tissue that they are located in. Kupffer cells are the hepatic macrophages. Histiocytes are macrophages seen in connective tissue. Dust cells are alveolar macrophage found in the respiratory tract. Langerhans cells are macrophages seen in the skin. Microglia are the central nervous system macrophages.

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  • 48. 

    During the preparation of a routine H&E slide, what allows the tissue to be visualized?

    • Fixation

    • Embedding in paraffin

    • Staining

    • Slicing

    • Dehydration

    Correct Answer
    A. Staining
    Explanation
    There are several steps in the preparation of a slide for microscopic examination. First, the tissue is "fixed" with formalin. This preserves it. After the tissue is fixed, it is dehydrated (dehydration will occur twice during slide preparation). The tissue sample is then embedded in paraffin. This forms a solid block, so that it can be placed in a microtome. It is then thinly sliced using a microtome. A thin slice of the specimen is then placed on a slide. The paraffin is removed by dissolving it with a chemical. The tissue is then rehydrated. In order to view the tissue, it is stained. After it is stained, it is again dehydrated. A coverslip is the mounted on top of it. The specimen is then ready for viewing.

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  • 49. 

    Which type of cartilage forms the skeleton of the fetus?

    • Hyaline cartilage

    • Elastic cartilage

    • Fibrocartilage

    • All of the above

    • None of the above

    Correct Answer
    A. Hyaline cartilage
    Explanation
    Hyaline cartilage forms the skeleton of the fetus. The cartilage forms a template of the bones. Endochondral ossification will occur during the childhood, replacing the hyaline cartilage with bone.

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  • Oct 18, 2024
    Quiz Edited by
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  • Jun 22, 2012
    Quiz Created by
    Mysticalraine

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