Hematology Chapter 21 The Lymphomas

46 Questions | By Darkrain9000 | Updated: Mar 21, 2022 | Attempts: 886

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1.

A Reed-Sternberg cell is large up to (____ u), abundant acidophilic cytoplasm, multinucleated or multi-lobed nucleus and gigantic inclusion-like nucleoli.
- A.
  
  30
- B.
  
  35
- C.
  
  45
- D.
  
  40
2.

Some of the main features of Nodular Lymphocyte-Predominant Hodgkin Lymphoma are mixture of small, normal- appearing lymphocytes, benign histiocytes, sometimes Reed-Sternberg cells, and variable amount of pale-staining cytoplasm, large convoluted nucleus(" ____ shaped") with deleicate nuclear membrane and fine chromatin indistinct nucleolus- cell phenotypically related centroblasts.
- A.
  
  Almond
- B.
  
  Balloon
- C.
  
  Raisin
- D.
  
  Popcorn
3.

Which of these do not appear in Nodular Lymphocyte-Predominant Hodgkin Lymphoma.Slide 7
- A.
  
  Reed-Sternberg cells
- B.
  
  Eosinophils
- C.
  
  Histiocytes
- D.
  
  Plasma cells
- E.
  
  Popcorn cells
4.

Which Hodgkin Lymphoma features Lacunar cells?
- A.
  
  Classic Hodgkin Lymphoma-Nodular Sclerosis Hodgkin Lymphoma
- B.
  
  Nodular Lymphocyte-Predominant Hodgkin Lymphoma
5.

Which statement accurate describes lacunar cells?Slide 9
- A.
  
  Separated from surrounding cells by pale area, large, nucleoli small/medium
- B.
  
  Separated from surrounding cells by a dark area, small, nucleoli is small
6.

This is best shown with formalin-fixed tissue sections of sclerosis.Slide 9
- A.
  
  Plasma cells
- B.
  
  Lacunar cells
- C.
  
  Eosinophils
- D.
  
  Histiocytes
7.

Lymphocytes are sparse, Reed-Sternberg cells are numerous. Plasma cells, histiocytes, eosinophils infrequent
- A.
  
  Lymphocyte Rich Hodgkin Lymphoma
- B.
  
  Lymphocyte Depletion Hodgkin Lymphoma
8.

Lymphocyte exhibits large numbers of lymphocytes and small numbers of Reed-Sternberg. This describes what type of Lymphoma?
- A.
  
  Lymphocyte Rich Hodgkin Lymphoma
- B.
  
  Lymphocyte Depletion Hodgkin Lymphoma
9.

This form of Lymphoma has predominance of males and younger people, usually localized with one node group, good long-term survival, but some incidence of late relapses.
- A.
  
  Nodular Lymphocyte Predominant Hodgkin Lymphoma
- B.
  
  Nodular Sclerosis Hodgkin Lymphoma
10.

Female predominance, associated with anterior mediastinal mass, adenopathy( gland enlargement), usually asymptomatic at first presentation
- A.
  
  Nodular Lymphocyte Predominant Hodgkin Lymphoma
- B.
  
  Nodular Sclerosis Hodgkin Lymphoma
11.

Hodgkin Lymphoma accounts for approximately ______% of new lymphoma cases in U.S.
- A.
  
  5%
- B.
  
  10%
- C.
  
  15%
- D.
  
  20%
12.

Hodgkin Lymphoma is more common in ages ________ and also over 50.
- A.
  
  10-20
- B.
  
  5-10
- C.
  
  15-35
13.

Hodgkin Lymphoma is usually present with painful lymph node swelling.
- A.
  
  True
- B.
  
  False
14.

Ann Arbor Classification for Hodgkin Lymphoma. Stage I involve how many lymph node regions?
- A.
  
  1
- B.
  
  2
- C.
  
  3
- D.
  
  4
15.

Involving Ann Arbor Hodgkin Lymphoma III1 stands for what?
- A.
  
  With or without splenic, hilar, celiac, portal nodes
- B.
  
  With para-aortic, iliac, mesenteric nodes
16.

Involving the Ann Arbor Classification, Stage II involves how many lymph node regions and on how many sides?
- A.
  
  1 lymph node region on one side
- B.
  
  2 or more lymph node regions on BOTH sides
- C.
  
  2 or more lymph node regions on one sides
- D.
  
  3 or more lymph node regions on BOTH sides.
17.

In Ann Arbor Classification Stage 3 has lymph nodes on both sides of the diaphragm or one side?
- A.
  
  Both sides
- B.
  
  One side
18.

In Ann Arbor classification(Cotswold modification) stage 4 has extra nodal sites ("A" designates what?)
- A.
  
  Asymptomatic
- B.
  
  Symptomatic
19.

In Ann Arbor classification(Cotswold modification) stage 4 has extra nodal sites ("B" designates what?)
- A.
  
  Asymptomatic
- B.
  
  Symptomatic
20.

Lymphomas develop due to damage of genetic code that regulates growth and reporduction of immune system cells: transolcations, deletions, mutations etc.
- A.
  
  True
- B.
  
  False
21.

Growth regulating genes that function abnormally when translocated are called oncogenes.
- A.
  
  True
- B.
  
  False
22.

Revised European American Classification of Lymphoid Neoplasms is what?
- A.
  
  The most widely used for Non-Hodgkin Lymphoma
- B.
  
  The most widely used for Hodgkin Lymphoma
- C.
  
  The least widely used for Non-Hodgkin Lymphoma
23.

NHLs may arise from any lymph node cells: B-cell lymphomas( ____%)slide 16
- A.
  
  40-50
- B.
  
  85-90
- C.
  
  20-30
- D.
  
  10-15
24.

NHLs may arise from any lymph node cells: T-cell lymphomas( ____%)slide 16
- A.
  
  40-50
- B.
  
  85-90
- C.
  
  20-30
- D.
  
  10-15
25.

Germinal Center contains centrocytes which are what kind of B cells?
- A.
  
  Resting B cells
- B.
  
  Proliferating B cells