Chromosomes And Recombination

1. Indications for ordering a chromosome analysis include:

Growth and development abnormalities

Family history of chromosomal abnormalities

Infertility, still births, or neonatals death

Pregnancy with advanced maternal age

All of the above

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4. FISH :

Detects a specific positions on a chromosome

Paints whole chromosomes

Stands for fluorescence in situ hybridization

A and C

B and C

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6. A complete mole is:

Diploid and has chromosomes all from paternal origin

Has a small atrophic fetus

Contains no fetus or placenta

Has an extra paternal chromosome set

A and C only

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8. Genetic linkage analysis is based on:

PCR and computer analysis

Probability of meiotic recombination events

Physical map of the DNA making up the chromosome

Number of people in a population

Patchwork inheritance pattern of DNA

9. Possible manifestations of Down Syndrome are

Transverse palmar crease and flat wide bridge of nose

Microcephaly, and protruding tongue

Acute lympocytic leukemia

A, B, and C

A and C only

10. If there are one or more crossovers, then the ratio of non-recombinant: recombinant genotypes will be:

1:2

2:1

1:1

1:3

Unknown