Chemotherapy Drugs II
Natural product-derived antineoplastic agents
- 1.
Which of the following work by intercalting into DNA?
- A.
Actinomycin D
- B.
Irenotecan
- C.
Tamoxifen
- D.
Daunorubicin
- E.
Vincristine
Correct Answer(s)
A. Actinomycin D
D. Daunorubicin -
- 2.
Which of the following destabilizes microtubule formation?
- A.
Irenotecan
- B.
Paclitaxel
- C.
Ixabepilone
- D.
Vinblastine
- E.
Etoposide
Correct Answer
D. Vinblastine -
- 3.
Which of the following stabilizes microtubule formation?
- A.
Irenotecan
- B.
Paclitaxel
- C.
Ixabepilone
- D.
Vinblastine
- E.
Etoposide
Correct Answer(s)
B. Paclitaxel
C. Ixabepilone -
- 4.
Which of the following drugs works by blocking estrogen response?
- A.
Doxorubicin
- B.
Actinomycin D
- C.
L-Asparaginase
- D.
Etoposide
- E.
Tamoxifen
Correct Answer
E. Tamoxifen -
- 5.
Which of the following chemotherapy agents inhibit topoisomerase function?
- A.
Actinomycin D
- B.
Etoposide
- C.
Irenotecan
- D.
Bleomycin
- E.
Tamoxifen
Correct Answer(s)
B. Etoposide
C. Irenotecan -
- 6.
Resistance to which of the following can be acquired via altered tubulin and/or P-glycoprotein activity?
- A.
Ixabepilone
- B.
Paclitaxel
- C.
Bleomycin
- D.
L-Aspariginase
- E.
Vincristine
Correct Answer(s)
A. Ixabepilone
B. Paclitaxel
E. Vincristine -
- 7.
Which of the following are in the subclass Carcinolytic Antibiotics?
- A.
Vinblastine
- B.
Bleomycin
- C.
Vincristine
- D.
Actinomycin D
- E.
Daunorubicin
Correct Answer(s)
B. Bleomycin
D. Actinomycin D
E. Daunorubicin -
- 8.
Which of the following are antimitotic agents?
- A.
Doxorubicin
- B.
Vincristine
- C.
Vinblastine
- D.
Tamoxifen
- E.
Paclitaxel
Correct Answer(s)
B. Vincristine
C. Vinblastine
E. Paclitaxel -
- 9.
Which of the following is commonly used to treat childhood cancers such as Ewing's sarcoma and Wilms' Tumor?
- A.
Vincristine
- B.
Vinblastine
- C.
Etoposide
- D.
Bleomycin
- E.
Actinomycin D
Correct Answer
E. Actinomycin DExplanation
Easy way to remember this is that children ACT out (ACTinomycin D)Rate this question:
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- 10.
Which of the following drugs causes peripheral neuropathy?
- A.
Paclitaxel
- B.
Irenotecan
- C.
Vinblastine
- D.
Vincristine
- E.
Ixabepilone
Correct Answer(s)
A. Paclitaxel
D. Vincristine
E. IxabepiloneExplanation
These are the three antimitotic agents that cause peripheral neuropathy. Note that Vinblastine does not, but does cause Bone Marrow Suppression.Rate this question:
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Jan 09, 2013Quiz Edited by
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Jan 31, 2010Quiz Created by
Cody284
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