Chromatography Methods Quiz Questions

24 Questions | Total Attempts: 305

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Chromatography Quizzes & Trivia

Questions and Answers
  • 1. 
    List the types of substances to which each of the following chromatographic methods is most applicable:  Gas- Liquid
  • 2. 
    List the types of substances to which each of the following chromatographic methods is most applicable:  Liquid- adsorption
  • 3. 
    List the types of substances to which each of the following chromatographic methods is most applicable:     Gas- solid
  • 4. 
    List the types of substances to which each of the following chromatographic methods is most applicable:   Ion exchange
  • 5. 
    The weak mobile phase is a non-polar solvent (hexane, benzene) and the strong mobile phase is a polar solvent (water, methanol) is for polar supports
    • A. 

      True

    • B. 

      False

  • 6. 
    The weak mobile phase is a polar solvent and the strong mobile phase is a non-polar solvent for non-polar supports.
    • A. 

      True

    • B. 

      False

  • 7. 
    Isocratic elution
  • 8. 
    Changing the composition of the mobile phase with time aka solvent programming:
  • 9. 
    2 Describe three general methods for improving resolution in partition chromatography.
    • A. 

      Adjustment of kA and kB by employing a multicomponent mobile phase and varying the raiot of the solvents to find an optimal mixture.

    • B. 

      Variation in the chemical composition of the solvent system in such a way as to make α larger.

    • C. 

      Employing a different packing in which α is greater.

    • D. 

      Going from a weak mobile phase to a strong one

  • 10. 
    Describe a way to manipulate the retention factor of a solute in partition chromatography
  • 11. 
    How can the selectivity factor be manipulated in (a) gas chromatography and (b) LC?
  • 12. 
    In a stop-flow injection
  • 13. 
    A reversed-phase packing
  • 14. 
    In a normal-phase packing, 
  • 15. 
    ) In ion-pair chromatography 
  • 16. 
    In ion chromatography
  • 17. 
    A bulk property detector
  • 18. 
     A solute property detector 
  • 19. 
    Sparging
  • 20. 
    What is a guard column in partition chromatography?
  • 21. 
    What ways are normal- phase partition chromatography and adsorption chromatography similar?
  • 22. 
    Describe the fundamental difference between adsorption and partition chromatography.
  • 23. 
    Describe the fundamental difference between ion-exchange and size- exclusion chromatography
  • 24. 
    What types of species can be separated by HPLC but not GC?
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