Blood Cells MCQ For Nursing Students
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Mcq for nursing students (2nd year) biochemistry course - mid way point in blood cell lecture series
Questions and Answers
- 1.
Select the statement about red blood cells that is incorrect.
- A.
Mature red blood cells lack nuclei.
- B.
Red blood cells contain hemoglobin.
- C.
Deoxyhemoglobin carries oxygen.
- D.
Red blood cells lack mitochondria.
Correct Answer
C. Deoxyhemoglobin carries oxygen.Explanation
The statement "Deoxyhemoglobin carries oxygen" is incorrect. Deoxyhemoglobin is the form of hemoglobin that does not carry oxygen, while oxyhemoglobin is the form that binds to oxygen.Rate this question:
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- 2.
Which dietary component(s) is/are needed for DNA synthesis, and thus greatly influence the production of red blood cells?
- A.
Calcium
- B.
Iron
- C.
Vitamin B12 and folate
- D.
Protein
Correct Answer
C. Vitamin B12 and folateExplanation
Vitamin B12 and folate are needed for DNA synthesis and greatly influence the production of red blood cells. These two nutrients play a crucial role in the production and maturation of red blood cells in the bone marrow. They are involved in the synthesis of DNA, which is necessary for the proper division and growth of cells, including red blood cells. Deficiencies in vitamin B12 and folate can lead to impaired DNA synthesis and result in megaloblastic anemia, a condition characterized by the production of large, immature red blood cells. Therefore, ensuring an adequate intake of vitamin B12 and folate is essential for the production of red blood cells.Rate this question:
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- 3.
Which blood cell can be described as being a biconcave disc?
- A.
Platelet
- B.
Neutrophil
- C.
Eosinophil
- D.
Erythrocyte
Correct Answer
D. ErythrocyteExplanation
The correct answer is erythrocyte. Erythrocytes, also known as red blood cells, are biconcave discs. This means that they have a concave shape on both sides, resembling a shallow bowl. This unique shape allows erythrocytes to have a large surface area-to-volume ratio, which is important for their main function of carrying oxygen throughout the body. The biconcave shape also allows erythrocytes to be flexible and squeeze through narrow blood vessels.Rate this question:
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- 4.
Which of the following directly defines the transportation of oxygen?
- A.
Haemoglobin
- B.
Oxyhaemoglobin
- C.
Deoxyhaemoglobin
- D.
Red cell count
Correct Answer
B. OxyhaemoglobinExplanation
Oxyhaemoglobin directly defines the transportation of oxygen. Oxyhaemoglobin is formed when oxygen molecules bind to haemoglobin in red blood cells. It is the main form in which oxygen is transported from the lungs to the tissues in the body. This process allows for the efficient delivery of oxygen to cells for cellular respiration and energy production.Rate this question:
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- 5.
Red blood cells survive around _____ days.
- A.
120
- B.
240
- C.
10
- D.
360
Correct Answer
A. 120Explanation
Red blood cells, also known as erythrocytes, have a lifespan of approximately 120 days. They are continuously produced in the bone marrow and are responsible for carrying oxygen to different parts of the body. After around 120 days, they become old and damaged, and are removed from circulation by the spleen and liver. New red blood cells are constantly being produced to replace the old ones, ensuring a healthy supply of oxygen throughout the body.Rate this question:
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- 6.
Erythropoietin appears in the plasma when peripheral tissues, especially the kidneys, are exposed to:
- A.
High urine volumes
- B.
Low oxygen concentrations
- C.
Excessive amounts of radiation
- D.
Extremes of temperature
- E.
None of the above
Correct Answer
B. Low oxygen concentrationsExplanation
Erythropoietin is a hormone that is released in response to low oxygen concentrations in the body. When the kidneys and other peripheral tissues detect low oxygen levels, they produce and release erythropoietin into the bloodstream. This hormone then stimulates the production of red blood cells in the bone marrow, which helps to increase the oxygen-carrying capacity of the blood. Therefore, the correct answer is low oxygen concentrations.Rate this question:
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- 7.
Iron is necessary in the diet because it is involved with: [
- A.
Hemoglobin production
- B.
Prevention of hemolysis
- C.
Prevention of sickle cell anemia
- D.
All of the above
- E.
None of the above
Correct Answer
A. Hemoglobin productionExplanation
Iron is necessary in the diet because it is involved in hemoglobin production. Hemoglobin is a protein in red blood cells that carries oxygen from the lungs to the rest of the body. Iron is a crucial component of hemoglobin, as it binds to oxygen and allows it to be transported throughout the body. Without sufficient iron, the body cannot produce enough hemoglobin, leading to a condition called iron-deficiency anemia. Therefore, iron is essential for the production of hemoglobin and proper oxygen transport in the body.Rate this question:
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- 8.
The primary site of erythropoiesis in the adult is the:
- A.
Kidney
- B.
Liver
- C.
Bone marrow
- D.
All of the above
- E.
None of the above
Correct Answer
C. Bone marrowExplanation
The bone marrow is the primary site of erythropoiesis in adults. Erythropoiesis is the process of producing red blood cells, and it occurs in the bone marrow. The bone marrow contains stem cells that differentiate into red blood cells, and these cells go on to carry oxygen throughout the body. The kidney and liver also play a role in erythropoiesis, but they are not the primary sites.Rate this question:
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- 9.
Which of the following statements are incorrect : Glucose 6 phosphate dehydrogenase deficiency results in:
- A.
Reduction NADPH production
- B.
Superoxide damage to erythrocytes
- C.
Production of heinz bodies
- D.
Haemolytic anaemia
- E.
Reduction in ATP production
- F.
All of the above
- G.
None of the above
Correct Answer
E. Reduction in ATP productionExplanation
Glucose 6 phosphate dehydrogenase deficiency leads to a reduction in NADPH production, which is necessary for maintaining the reduced state of glutathione and protecting erythrocytes from oxidative damage. This deficiency also causes the production of Heinz bodies, which are denatured hemoglobin aggregates that can damage erythrocytes. Both of these factors contribute to the development of hemolytic anemia. However, glucose 6 phosphate dehydrogenase deficiency does not directly affect ATP production, so the statement "reduction in ATP production" is incorrect.Rate this question:
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- 10.
Deoxygenation of haemoglobin can result as a consequence of:
- A.
Low oxygen levels
- B.
Production of 2,3 BPG
- C.
Binding of CO
- D.
Decrease in pH
- E.
High levels of CO2
- F.
All of the above
- G.
None of the above
Correct Answer
F. All of the aboveExplanation
Deoxygenation of hemoglobin can occur due to multiple factors. Low oxygen levels in the blood can lead to the release of oxygen from hemoglobin. The production of 2,3 BPG (2,3-bisphosphoglycerate) can also cause a decrease in the affinity of hemoglobin for oxygen, leading to its release. Binding of carbon monoxide (CO) to hemoglobin can prevent the binding of oxygen, resulting in deoxygenation. A decrease in pH, such as in acidic conditions, can also cause hemoglobin to release oxygen. High levels of carbon dioxide (CO2) can stimulate the release of oxygen from hemoglobin. Therefore, all of the above factors can contribute to the deoxygenation of hemoglobin.Rate this question:
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- 11.
Sickle cell anaemia occurs because of:
- A.
A mutation in the pyphorin ring of haem
- B.
An inability to incorporate Fe2+ into haem
- C.
A mutation in beta globin
- D.
A decrease in the amount of beta globin produced
- E.
A decrease in the amount of alpha globin produced
- F.
All of the above
- G.
None of the above
Correct Answer
C. A mutation in beta globinExplanation
Sickle cell anaemia occurs because of a mutation in beta globin. This mutation causes the red blood cells to become misshapen and rigid, leading to a variety of symptoms such as pain, fatigue, and organ damage. The mutation affects the structure of the haemoglobin molecule, which is responsible for carrying oxygen in the blood. This mutation results in the production of abnormal haemoglobin, known as haemoglobin S, which causes the red blood cells to take on a sickle shape. This abnormal shape makes it difficult for the red blood cells to flow through small blood vessels, leading to a lack of oxygen delivery to tissues and organs.Rate this question:
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- 12.
Circulating mature RBCs lack:
- A.
Ribosomes
- B.
Mitochondria
- C.
Nucleus
- D.
All of the above
- E.
None of the above
Correct Answer
D. All of the aboveExplanation
Circulating mature RBCs lack ribosomes, mitochondria, and a nucleus. This is because during their maturation process, these components are expelled to make space for more hemoglobin, which is essential for oxygen transport. Without ribosomes, RBCs cannot synthesize proteins. Without mitochondria, they cannot generate energy through aerobic respiration. And without a nucleus, RBCs cannot undergo cell division or repair themselves. Therefore, all of the above options are correct.Rate this question:
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- 13.
The part of the hemoglobin molecule that directly interacts with oxygen is:
- A.
Globin
- B.
The sodium ion
- C.
The tertiary protein structure
- D.
The iron ion
- E.
None of the above
Correct Answer
D. The iron ionExplanation
The iron ion is the part of the hemoglobin molecule that directly interacts with oxygen. Hemoglobin is a protein found in red blood cells that carries oxygen throughout the body. The iron ion within the heme group of hemoglobin binds to the oxygen molecule, allowing for oxygen transport in the bloodstream. The interaction between the iron ion and oxygen is crucial for the oxygen-carrying capacity of hemoglobin.Rate this question:
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Mar 22, 2023Quiz Edited by
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Oct 04, 2011Quiz Created by
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