Block 7 Skin Creighton Univ W Xpl Prt 1

20 Questions | Total Attempts: 120

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Skin Quizzes & Trivia

Mostly from creighton but some from academic success.


Questions and Answers
  • 1. 
    INTEGUMENTARY EMBRYOLOGY  Melanocytes are found in which epidermal layer?
    • A. 

      Stratum basale

    • B. 

      Stratum corneum

    • C. 

      Stratum granulosum

    • D. 

      Stratum lucidum

    • E. 

      Stratum spinosum

  • 2. 
    A young black girl shows isolated patches of skin and hair that lack melanin pigment. In addition, other skin lesions are observed that look suspiciously like a malignant melanoma. What is the most likely diagnosis?
    • A. 

      Type I oculocutaneous albinism

    • B. 

      Type II oculocutaneous albinism

    • C. 

      Piebaldism

    • D. 

      Ichthyosis

    • E. 

      Psoriasis

  • 3. 
    A young infant shows extremely stretchable and fragile skin, hypermobile joints, and cigarette-paper scars over the knees. What is the most likely diagnosis?
    • A. 

      Ehlers-Danlos syndrome

    • B. 

      Junctional epidermolysis bullosa

    • C. 

      Psoriasis

    • D. 

      Lchthyosis

    • E. 

      Piebaldism

  • 4. 
    A young infant shows skin blisters over the entire body with generalized skin erosion. Pathology indicates a cleft between the epidermis and dermis. What is the most likely diagnosis?
    • A. 

      Psoriasis

    • B. 

      Junctional epidermolysis bullosa

    • C. 

      Ichthyosis

    • D. 

      Ehlers-Danlos syndrome

    • E. 

      Type II Oculocutaneous albinism

  • 5. 
    The administration of which of the following agents may result in discoloration of both deciduous and permanent teeth?
    • A. 

      Cephalosporin

    • B. 

      Chloramphenicol

    • C. 

      Erythromycin

    • D. 

      Penicillin

    • E. 

      Tetracycline

  • 6. 
    Which of the following cell types is normally not found in the epidermis?
    • A. 

      Keratinocyte

    • B. 

      Melanocyte

    • C. 

      Langerhans cell

    • D. 

      Merkel cell

    • E. 

      Dendrocyte

  • 7. 
    Bullus pemphigoid is an autoimmune disorder that attacks the basement membrane between the epidermis and the dermis via IgG antibodies. Between what two layers would the IgG be deposited?
    • A. 

      Stratum basale and reticular dermis

    • B. 

      Stratum basale and papillary dermis

    • C. 

      Stratum spinosum and reticular dermis

    • D. 

      Stratum spinosum and papillary dermis

    • E. 

      Stratum spinosum and stratum basale

  • 8. 
    A patient presents with a 3 month history of progressive weakness. On physical examination, you find bilateral decreases in strength in the legs and back. In addition, she has a rash surrounding both eyes. Laboratory values are significant for elevated LDH and CPK, and a positive ANA. What is the diagnosis?
    • A. 

      SLE

    • B. 

      Myasthenia gravis

    • C. 

      Lambert-Eaton syndrome

    • D. 

      Scleroderma

    • E. 

      Dermatomyositis

  • 9. 
    A 70 year old man presents with discomfort in his thigh for 2 months. X ray revealed a radiolucent mass without any calcification. Biopsy of the tissue showed a pinwheel pattern of fibroblasts. Which soft tissue tumor does he most likely have?
    • A. 

      Liposarcoma

    • B. 

      Fibrosarcoma

    • C. 

      Malignant fibrous histiocytoma

    • D. 

      Lipoma

  • 10. 
    Rhabdomyosarcoma is the most common soft tissue tumor of which age group?
    • A. 

      0-15

    • B. 

      15-30

    • C. 

      30-50

    • D. 

      50-70

    • E. 

      70+

  • 11. 
    A 50 year old man has had a painless, slowly enlarging mass in his arm for the past 2 years. A biopsy reveals a herringbone pattern. What is the most likely diagnosis?
    • A. 

      Liposarcoma

    • B. 

      Fibrosarcoma

    • C. 

      Malignant fibrous histiocytoma

    • D. 

      Lipoma

  • 12. 
    • A. 

      Kearns-Sayre syndrome

    • B. 

      Becker muscular dystrophy

    • C. 

      Polymyositis

    • D. 

      Dermatomyositis

    • E. 

      Nemaline myopathy

  • 13. 
    You are looking at a biopsy specimen from a suspicious skin lesion. The tissue consists mainly of spindle cells in a storiform pattern, and it stains with CD34. What is the most appropriate statement to tell the patient?
    • A. 

      This is characteristic of basal cell carcinoma, which rarely metastasizes.

    • B. 

      This is characteristic of dermatofibrosarcoma, a rare but treatable skin cancer.

    • C. 

      This is characteristic of actinic keratosis, a precursor to squamous cell carcinoma

    • D. 

      This is characteristic of keratoacanthoma, a neoplasm that heals spontaneously

  • 14. 
    A 45 year old patient presents to you with dozens of velvety pigmented papules on his trunk and extremities that appear stuck on. He is concerned since he had very few nevi before 3 months ago. Which of the following aspects of his history is most relevant to his current lesions:
    • A. 

      He works as a charter fishing guide in Florida

    • B. 

      He has a 40 pack/year history of smoking

    • C. 

      He has had 20 lifetime male sexual partners

    • D. 

      He has controlled diabetes

  • 15. 
    After walking in the woods while wearing sandals, a 20 year old man develops a weeping erythematous rash with vesicles. Which type of cell is least likely to be involved in this reaction?
    • A. 

      Neutrophil

    • B. 

      Langerhans cell

    • C. 

      CD4+ T cell

    • D. 

      CD8+ T cell

  • 16. 
    Erythema multiforme is a hypersensitivity reaction in the skin characterized by targetoid vesicles. It can be triggered by infection, drugs, and malignancy, among others. How is Stevens-Johnson syndrome different from erythema multiforme?
    • A. 

      Stevens-Johnson syndrome involves mucosal membranes

    • B. 

      Stevens-Johnson syndrome is only involved on the the extremities

    • C. 

      Stevens-Johnson syndrome is a type IV hypersensitivity reaction, not a type II like erythema multiforme

    • D. 

      Stevens-Johnson syndrome is not triggered by drugs

  • 17. 
    The H&E of a skin biopsy seen below was most likely taken from a patient with:
    • A. 

      Superficial spreading melanoma

    • B. 

      Squamous cell carcinoma

    • C. 

      Basal cell carcinoma

    • D. 

      Bullus pemphigoid

    • E. 

      Seborrheic keratosis

  • 18. 
    How would you treat a patient with the lesion seen in this skin biopsy?
    • A. 

      Antibiotics

    • B. 

      Antivirals

    • C. 

      Resection of lesions

    • D. 

      Steroids

    • E. 

      Allopurinol

  • 19. 
    This tissue section came from a skin lesion that is best described as:
    • A. 

      Common, malignant

    • B. 

      Rare, malignant

    • C. 

      Common, benign

    • D. 

      Rare, benign

    • E. 

      Common, precursor of malignancy

  • 20. 
    Your patient has an erythematous, weeping lesion on her face. If you treat this lesion with steroids, which of the following preparations is most appropriate?
    • A. 

      Non-fluorinated ointment

    • B. 

      Non-fluorinated cream

    • C. 

      Non-fluorinated lotion

    • D. 

      Fluorinated ointment

    • E. 

      Fluorinated cream

    • F. 

      Fluorinated lotion