How much do you know about multifactorial inheritance? Multifactorial inheritance relates to a complex genetic inheritance due to a combination of multiple genetic factors and environmental causes. It is a disorder caused by these factors, including a broad range of cardiac diseases, neural tube defects, and specific mental illnesses. This quiz highlights the problems of multifactorial inheritance. Don’t forget to get your certificate when you have completed the quiz.
Brother
Nephew
Grandchild
Aunt
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Additive effects
Shared environment
Assortative mating
Polyaenic inheritance
Disruptive selection
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Diabetes type 2
Neural tube defect
Hirschsprungs disease
Hip circumference
Red/green color blindness
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The daughter of an alcoholic father
The son of an alcoholic father
The son of an alcoholic mother
The daughter of an alcoholic mother
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Increased risk due to severe symptoms
Linkage disequilibrium
High risk in females
Low heritability
A major gene
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The recurrence risk after the birth of an affected child is close to 3%
The recurrence risk after the birth of two affected children is as high as the recurrence risk after the birth of one affected child
Concordance between identical twins is close to 1000/0
The recurrence risk after the birth of an affected child is not significantly increased above the population incidence
The clinical severity of the defect in an affected child is unrelated to the recurrence risk
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Pancreatic p-cell autoantibodies are frequently present
Approximately 10% of affected indivifuals have an affected sibling
Onset of disease is usually in childhood
The concordance rate in morozygotic twins is approximately 30%.
The concordance rate in monozygotic twins is five times that in dizygotic twins
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Multifactorial and autosornal dominant diseases but not autosomal recessive diseases and chromosome aberrations
Autosomal recessive diseases and chromosome aberrations, but not autosornal dominant and multifactorial diseases
Autosomal dominant and autosomal recessive diseases but not multifactorial diseases and chromosome aberrations
Multifactorial and autosomal recessive diseases, but not autosomal dominant diseases and chromosome aberrations
Multifactorial diseases and chromosome aberrations but not autosomal dominant and autosomal recessive diseases
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Measurement error
Nonadditive genes
Nonshared environment
Assortative mating
Shared environment
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Most of the cases caused by dominant diseases come from new mutations
Most of the cases caused by autosomal recessive genes are due to new mutations
Most dominant alleles are hidden in heterozygotes
The recessive alleles lost are insignificant compared to those hidden in heterozygotes
The phenotypes is a side effect of elements that are beneficial to mankind
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New mutations are important for schizophrenia risk
Old father means dysfunctional family leading to bad environment
Schizophrenia must be caused by non-disjunction
The age of the father changes how imprinting works
Additive effects of several bad alleles are causative
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1%
10 %
3.3 %
0.1 %
25 %
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Nonshared environment
Assortative mating
Additive gene effects
Shared environment
Non-additive gene effects
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