Block 7 Male Female Repro Physio W/Exp
From the Awesome Dr Keator S2_Male Reproductive Physiology Quiz_Questions_Fall 2012 S2_Female Reproductive Physiology Quiz_Questions_Fall 2012
- 1.A 26-year-old man visits his primary care physician (PCP) complaining of lethargy and muscle weakness. Upon history, the patient also reveals decreased libido, and that he is unable to maintain an erection during intercourse. The PCP suspects this man may have decreased levels of testosterone. Which of the following hormone assays should the PCP order to determine if this man has an impaired hypothalamic-pituitarytesticular axis?
- A.
Testesterone and dihydrotestosterone
- B.
Dihydrotestosterone and prolactin
- C.
Testosterone and follicle stimulating hormone
- D.
Luteinizing hormone and follicle stimulating hormone
- E.
Testosterone and luteinizing hormone
- 2.A 24-year-old man visits his dermatologist. The man is extremely upset because he is suffering from male pattern baldness. The patient explains that none of his older brothers exhibit male pattern baldness. The patient further complains that he was under the assumption that hair growth and baldness were traits inherited through his mother's genes, and he notes his maternal grandfather is 76-years-old and sporting a full head of thick hair. Which of the following hormones is most likely elevated in this patient?
- A.
Testosterone
- B.
Dehydroepiandrosterone (DHEA)
- C.
Androstenedione
- D.
Androstenediol
- E.
Dihydrotestosterone
- 3.A 29-year-old man visits his urologist for a vasectomy. The patient explains that he is sexually active with multiple partners and does not want to father a child. Following the procedure, how long should the man abstain from intercourse to ensure he does not become a father?
- A.
1-2 weeks
- B.
3-4 weeks
- C.
4-6 weeks
- D.
6-10 weeks
- E.
10-15 weeks
- 4.A 57-year-old man visits his urologist complaining of the sudden onset of a sexuallyrelated concern. The patient explains that he and his wife enjoy intercourse 3 to 4 times each week, but within the past 2 weeks he has been unable to ejaculate, yet mentally feels like he has achieved an orgasm. The patient further explains that he has had no difficulty in becoming aroused, he has always achieved a full erection, and has experienced no difficulties maintaining an erection during intercourse. The patient denies taking any erectile dysfunction drugs (e.g. Viagara). Physical exam is unremarkable; lab results reveal normal levels of testosterone and luteinizing hormone. Which of the following is the most likely cause of this patient's symptoms and signs?
- A.
Impaired release of nitric oxide
- B.
Lack of emission
- C.
Impaired penile nervous system resulting in lack of ejaculatory stimuli
- D.
The patient is depressed and failure to ejaculate is a psychological problem
- E.
Reduced blood flow to the corpus cavernosa
- 5.A 33-year-old man presents to a clinic complaining of infertility. He previously fathered a child with another woman, but explains that he and his wife have been having unprotected intercourse for the past 14 months and have been unable to get pregnant. Multiple semen analyses taken two weeks apart reveal oligospermia (sperm count 100,000 sperm/mL) with normal motility. Testosterone levels are in the normal range. Which hormone is most likely reduced in this man?
- A.
Luteinizing Hormone
- B.
Prolactin
- C.
Follicle Stimulating Hormone
- D.
Estradiol
- E.
Gonadotropin releasing hormone
- F.
Dihydrotestosterone
- 6.A 56-year-old man complains of urinary incontinence. Digital rectal exam (DRE) reveals an abnormally-shaped and enlarged prostate gland pushing on the man's bladder. Which of the following biomarkers is most likely elevated in this patient?
- A.
Testosterone
- B.
Dihydrotestosterone
- C.
Luteinizing hormone
- D.
Aromatase
- E.
Prostate specific antigen
- 7.The Tanner scale (i.e. Tanner Stage) is used by pediatricians to correlate changes in anatomy with the onset of physiological hormone production during puberty. A 13-yearold girl was taken to her pediatrician for a physical exam. This girl was classified as Tanner Stage 2. What are the common physical and physiological characteristics of this young girl?
- A.
Adrenarche, axillary hair
- B.
Breast buds, accelerated growth
- C.
Projection of aerola, menses
- D.
Villus hair, basal growth
- E.
Coarse pubic hair, acne
- 8.The majority of a woman's follicles are lost due to atresia. At what age does the greatest rate of atresia usually occur?
- A.
During puberty before regular cyclicity
- B.
During the toddler years
- C.
During a woman's cyclical years
- D.
During peri-menopause while experiencing irregular cyclicity
- E.
During fetal development
- 9.Theca interna cells and granulosa cells work synergistically to generate ovarian hormones. If a woman is treated with a luteinizing hormone (LH) receptor antagonist during the early proliferative phase of the menstrual cycle, which of the following adverse physiological responses is the most likely outcome?
- A.
LH levels will decline
- B.
The follicle will undergo atresia and die
- C.
Progesterone levels will increase
- D.
Androstenedione levels will increase
- E.
Estradiol levels will decline
- 10.The gonadotropins, follicle stimulating hormone (FSH) and luteinizing hormone (LH), in large part regulate ovarian function. Elevations in which of the following proteins predominantly inhibits the secretion of FSH?
- A.
Chorionic Gonadotropin
- B.
Progesterone
- C.
Testosterone
- D.
Inhibin
- E.
Activin
- 11.The dominant follicle is a highly vascularized structure that, following ovulation, evolves into a highly vascularized corpus luteum . Which of the following growth factors is most likely involved with the process of luteal angiogenesis?
- A.
Epidermal growth factor (EGF)
- B.
Vascular endothelial growth factor (VEGF)
- C.
Placental growth factor (pGF)
- D.
Insulin growth factor I (IGF1)
- E.
Insulin growth factor II (IGF2)
- 12.A 32-year-old woman complains of irregular menstrual cycles. Physical exam reveals galactorrhea; hyperprolactinemia is suspected. Decreased levels in which of the following hormones would confirm this diagnosis?
- A.
Acetylcholine
- B.
Dopamine
- C.
Prolactin releasing hormone
- D.
Nitric Oxide
- E.
Neuropeptide Y
- 13.A clinical researcher wants to administer a receptor antagonist designed to block growth of the dominant follicle. Inhibition of which receptor would most likely result in suppressed growth and development of the dominant follicle?
- A.
Estrogen receptor
- B.
Progesterone receptor
- C.
Luteinizing hormone receptor
- D.
Follicle stimulating hormone receptor
- E.
Gonadotropin releasing hormone receptor
- 14.Which of the following accurately describe the chronological set of descriptive changes that occur in the endometrium during the menstrual cycle?
- A.
Secretion, menstruation, proliferation, decidualization
- B.
Menstruation, decidualization, proliferation, secretion
- C.
Menstruation, secretion, decidualization, proliferation
- D.
Decidualization, menstruation, secretion, proliferation
- E.
Proliferation, secretion, decidualization, menstruation
- 15.A 29-year-old woman visits the gynecologist complaining of irregular cycles for the past 12 months. The patient further explains that her cycles range from 39 to 65 days, and that her menstrual period lasts for 2-3 days with very heavy menstrual blood flow. Physical and pelvic exams are unremarkable. Urinalysis is negative for chorionic gonadotropin (hCG). Which of the following is the best description and most likely cause of this patient's irregular menstrual cycles?
- A.
Dysfunctional uterine bleeding caused by polycystic ovary syndrome
- B.
Secondary amenorrhea caused by a luteal cyst
- C.
Dysmenorrhea caused by a uterine fibroid
- D.
Polymenorrhea caused by a follicular cyst
- E.
Oligomenorrhea caused by hyperplasia of the endometrium
- 16.A 37-year-old woman visits the gynecologist complaining of heavy menstrual bleeding. The woman is referred to a Women's Health Research Center. Her menstrual blood loss for three consecutive 29 day menstrual cycles is measured as 122 mL, 118 mL, and 93 mL, respectively. The patient indicated menstrual blood flow for approximately 4 days each menstrual period, and she has no complaints of pain. Plasma levels of estradiol and progesterone are in the normal range for the luteal phase of the menstrual cycle. Urinalysis is negative for chorionic gonadotropin (hCG); pelvic exam is unremarkable.
- A.
Polymenorrhea
- B.
Menorrhagia
- C.
Amenorrhea
- D.
Oligomenorrhea
- E.
Dysmenorrhea
- 17.A 25-year-old woman visits the gynecologist complaining of irregular menstrual cycles. Her cycles over the past year have been occurring every 7-10 weeks. Menstrual bleeding lasts for 3-5 days and there is no associated pain. Plasma levels of estradiol and progesterone are in the normal range for the luteal phase of the menstrual cycle. Urinalysis is negative for chorionic gonadotropin (hCG); pelvic exam is unremarkable. Which one of the following descriptions best defines this woman's menstrual periods?
- A.
Menorrhagia
- B.
Polymenorrhea
- C.
Amenorrhea
- D.
Oligomenorrhea
- E.
Dysmenorrhea
- 18.A 38-year-old primigravid woman complains of irregular menstrual cycles. Urinalysis is negative for chorionic gonadotropin. Physical exam reveals galactorrhea; otherwise unremarkable. Which of the following is the most likely cause of this patient's irregular menstrual cycles?
- A.
Elevated thyroid stimulating hormone
- B.
Elevated progesterone
- C.
Elevated prolactin
- D.
Elevated oxytocin
- E.
Elevated growth hormone
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Sample QuestionA 24 yo man visits his dermatologist. The man is extremely upset because he is suffering from male pattern baldness. None of his older brothers exhibit male pattern baldness. Further, this man was under the assumption that hair growth and baldness were traits inherited through his mother's genes, and he notes his maternal grandfather is 76 yo sporting a full head of thick hair. What hormone is usually elevated in young men experiencing male pattern baldness?
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