Pathology Of Female Reproductive System

18 Questions | Total Attempts: 1125

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Pathology Of Female Reproductive System

Disorders of the female reproductive system can occur as a result of disease in one of the many varied reproductive organs. In our study of the pathology of the female reproductive system we have been able to cover the disorders and how to diagnose them. Take the quiz and find out more.


Questions and Answers
  • 1. 
    The shown image from a Fallopian tube surgical specimen represents
    • A. 

      Salpingitis

    • B. 

      Hydrosalpinx

    • C. 

      Ectopic pregnancy

    • D. 

      Adenocarcinoma

    • E. 

      Clear cell carcinoma

  • 2. 
    A 33-year-old Caucasian female presents with a history of lower abdominal pain, fever, and purulent vaginal discharge. Pelvic examination reveals bilateral ovarian tenderness. Microscopic examination of the smears stained with Gram detects N. gonorrhoeae. Which of the following complications will most likely develop in this woman, if the disease is left untreated?
    • A. 

      Edometriosis

    • B. 

      Epithelial ovarian cancer

    • C. 

      Luteoma of pregnancy

    • D. 

      Ectopic pregnancy

    • E. 

      Amyloidosis

  • 3. 
    A 35-year-old female is evaluated for recurrent pregnancy loss. Pelvic MRI is shown. What is the cause of patient’s problem?
    • A. 

      Failure of Müllerian ducts to fuse

    • B. 

      Failure of Wolffian ducts to fuse

    • C. 

      Failure of Mullerian ducts to fuse with genitourinary sinus

    • D. 

      Failure of Wolffian ducts to fuse with genitourinary sinus

    • E. 

      Failure of Wolffian ducts to fuse with urogenital ridge

    • F. 

      Failure of Mullerian ducts to fuse with urogenital ridge

  • 4. 
    Few giant cells (shown) are found in Pap smear from an asymptomatic woman. Dx?
    • A. 

      Cervical intraepithelial neoplasia

    • B. 

      Carcinoma in situ

    • C. 

      Carcinoma

    • D. 

      HPV infection

    • E. 

      HSV infection

  • 5. 
    A correct statement about vulvar leukoplakia
    • A. 

      Progresses to cancer in 100% of cases

    • B. 

      Never progresses to cancer

    • C. 

      Is associated with underlying malignancy

    • D. 

      A white asymptomatic plaque

  • 6. 
    An elder woman presents with the shown vulvar disorder. How would you designate the findings before biopsy had been done?
    • A. 

      Leukoplakia

    • B. 

      Lichen sclerosus

    • C. 

      Lichen simplex chronicus

    • D. 

      Psoriasis

    • E. 

      Condyloma accuminatum

    • F. 

      Vulvar intraepithelial neoplasia

    • G. 

      Squamous cell carcinoma

  • 7. 
    Biopsy is taken and shown. Dx?
    • A. 

      Condyloma accuminatum

    • B. 

      Vulvar intraepithelial neoplasia

    • C. 

      Squamous cell carcinoma

    • D. 

      Lichen simplex chronicus

    • E. 

      Lichen sclerosus

  • 8. 
    Macro- and micro- presentation of the multiple lesions of the vulva is shown. Dx?
    • A. 

      Leukoplakia

    • B. 

      Condyloma accuminatum

    • C. 

      Verrucous carcinoma

    • D. 

      Squamous cell carcinoma

    • E. 

      Condylomata lata

  • 9. 
    Carcinoma in situ is characterized by
    • A. 

      Minimal stromal invasion

    • B. 

      Minimal lymph node metastases

    • C. 

      Minimal cellular atypia regardless presence/absence of stromal invasion or metastases

    • D. 

      Solely intraepithelial accumulation of obviously malignant cells

  • 10. 
    The shown image from a vulvar biopsy represents
    • A. 

      Papilloma

    • B. 

      Intraepithelial neoplasia

    • C. 

      Keratinizing squamous cell carcinoma

    • D. 

      Non-keratinizing squamous cell carcinoma

    • E. 

      Adenoma

    • F. 

      Adenocarcinoma

    • G. 

      Melanoma

  • 11. 
    A 40-year-old Caucasian female presents to the gynecologist for a routine checkup. Physical examination is unremarkable, but the Cytology report indicates presence of atypical squamous epithelial cells suspicious of high grade lesion (ASC-H). A biopsy is taken and the microscopic appearance of the specimen is shown for you evaluation. Which of the following is the most likely diagnosis?
    • A. 

      CIN 1

    • B. 

      CIN 2

    • C. 

      CIN 3

    • D. 

      Chronic cervicitis

    • E. 

      Carcinoma in situ

    • F. 

      Invasive squamous cell carcinoma

    • G. 

      Normal smear

  • 12. 
    A 41-year-old woman visits her family physician for a routine check-up.Her physical and, particularly, gynecologic examination is unremarkable, and Pap smear is taken.Cytologic examination reveals numerous small-to-medium-sized epithelial cells with markedly enlarged nuclei with accentuated nuclear outline, clumped chromatin and visible nucleoli.Which of the following procedures is the most reasonable in management of this patient?
    • A. 

      Repeat Pap smear in 6 month

    • B. 

      Colposcopy

    • C. 

      Colposcopy and cervical biopsy

    • D. 

      Ablation

    • E. 

      Conization

    • F. 

      Hysterectomy

  • 13. 
    A 23-year-old Caucasian woman visited her gynecologist for a regular checkup. Cervical Pap smear was taken (see the image below) and the cytologist recommended repeating cervical cytology in six months. What was the most like reason for such suggestion? 
    • A. 

      The lesion can progress to low-grade SIL

    • B. 

      The lesion can progress to high-grade SIL

    • C. 

      The lesion can directly progress to invasive carcinoma

    • D. 

      The patient has a sexually transmitted disease

  • 14. 
    A 33-year-old woman presents with vaginal bleeding.  At colposcopy, a vaginal mass is found and biopsied; subsequent histologic examination reveals atypical glands lined by large cells with clear cytoplasm, many of the cells have hobnail appearance.  Which of the following etiologic factors was most likely implicated in development of the shown pathology?
    • A. 

      HPV exposure

    • B. 

      Intrauterine folic acid deficiency

    • C. 

      Intrauterine x-ray exposure

    • D. 

      Peroral DES administration

    • E. 

      Intrauterine DES exposure

    • F. 

      Hormone-producing ovarian tumors

  • 15. 
    A 29-year-old promiscuous woman present to the gynecologist for a routine checkup. Physical examination is unremarkable, but the Pap smear report indicates the presence of atypical squamous epithelial cells of undermined significance (ASC-US). The smear is repeated in six months, but cytologic abnormalities persist. Subsequent cervical biopsy reveals epithelial changes shown for you evaluation. Which of the following is the most likely diagnosis?
    • A. 

      Normal cervix with non-keratinizing squamous epithelium

    • B. 

      Chronic cervicitis with repair

    • C. 

      Mild dysplasia

    • D. 

      Moderate dysplasia

    • E. 

      Severe dysplasia

  • 16. 
    A 74-year-old woman presents with a pruritic lesion on the external genitalia. The gross and microscopic appearance of the lesion is shown for your evaluation. Which of the following is the most likely diagnosis?
    • A. 

      Verrucous carcinoma

    • B. 

      Lichen simplex chronicus

    • C. 

      Lichen sclerosus

    • D. 

      Squamous cell carcinoma

    • E. 

      Extramammary Paget disease

  • 17. 
    A 26-year-old Hispanic female presents with oligomenorrhea and infertility. An endometrial biopsy is obtained at the twenty first day of menstrual cycle.  Histologic examination reveals small, slightly irregular glands and a few mitotic figures in the glands and stroma. Which of the following is the most likely cause of oligomenorrhea and infertility in this woman? 
    • A. 

      Anovulatory cycle

    • B. 

      Endometrial hyperplasia

    • C. 

      Endometrial polyp

    • D. 

      Chronic endometritis

    • E. 

      Endometrial carcinoma

  • 18. 
    A 48-year-old Caucasian female presents with vaginal bleeding. Endometrial biopsy reveals simple endometrial hyperplasia. Which of the following histologic changes in the endometrium allowed the pathologist to establish this diagnosis?
    • A. 

      Atrophic endometrium with cystically dilated glands

    • B. 

      Proliferative phase endometrium with few cystically dilated glands

    • C. 

      Crowded glands with outpounching and cytologic atypia

    • D. 

      Subnuclear vacuolation of the glandular epithelium

    • E. 

      Spiral arteries surrounded by decidual cells

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