Physiology-membrane Channels-cell Vol Reg

15 Questions | Total Attempts: 300

SettingsSettingsSettings
Please wait...
Physiology Quizzes & Trivia

Welcome to another quiz under the umbrella of physiology, where today we’ll be discussing the membrane channel – which is a family of biological membrane proteins which allow for water, ions and other solutes to move passively through the membrane. What do you know about it?


Questions and Answers
  • 1. 
    An increase in membrane thickness will have what effect on the rate of simple diffusion on a non-polar substance.
    • A. 

      Increase

    • B. 

      Decrease

    • C. 

      No Change

  • 2. 
    500 ml of 7 g/L Evans blue dye and 500 ml of 9 g/L antipyrine are given to a patient intravenously.  Two hours later a blood sample is taken and the concentration of Evans blue dye and antipyrine in the plasma are both 1 g/L.  Given the patient has a hematocrit of 30% and there is no lose of the indicators in their urine, what is the patient’s blood volume?
    • A. 

      3.5 L

    • B. 

      4.5 L

    • C. 

      5.0 L

    • D. 

      6.4 L

  • 3. 
    Loss of isotonic body fluid due to hemorrhage, urine, diarrhea or vomiting will result in:
    • A. 

      Loss of extracellular fluid volume but no change in extracellular osmolarity.

    • B. 

      Loss of extracellular fluid volume and decrease of extracellular osmolarity

    • C. 

      Loss of extracellular fluid volume and increase of extracellular osmolarity.

    • D. 

      Loss of intracellular fluid volume and decrease of intracellular osmolarity

    • E. 

      Loss of intracellular fluid volume and increase of intracellular osmolarity.

  • 4. 
    Which would be an appropriate cation associated with a glucose symporter (cotransporter)?
    • A. 

      K+

    • B. 

      H+

    • C. 

      Na+

    • D. 

      Li+

    • E. 

      Cl-

  • 5. 
    Select the diagram with the dotted line that represents the change in fluid volume that will occur as a result of an isotonic saline infusion. 
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

  • 6. 
    Which of the following is a primary determinant for movement of water across a membrane by osmosis?
    • A. 

      Permeability of the membrane to solutes

    • B. 

      Concentration of water on each side of the membrane.

    • C. 

      Ion channels

    • D. 

      Na+, K+-ATPase.

    • E. 

      Facilitated transport of glucose.

  • 7. 
    From the following list of choices pick the most important factor that determines the maximal rate of transport for substances (e.g. Na+ and glucose) via a cotransport carrier-mediated transport.
    • A. 

      The concentration gradient for Cl-.

    • B. 

      The transmembrane electrical gradient.

    • C. 

      The number of binding sites for either one of the transported substances.

    • D. 

      The electrical gradient for glucose.

  • 8. 
    Consider a solute found in the extracellular space and the membrane permeability to this solute is very low.  What would be the effect on intracellular osmolarity if there were loss of extracellular fluid containing this solute and the fluid lost were hypo-osmotic?
    • A. 

      Increase in intracellular osmolarity

    • B. 

      Decrease in osmolarity

    • C. 

      No change in osmolarity

    • D. 

      This cannot be predicted

  • 9. 
    You are asked to perform the following experiment on a red blood cell (RBC).  Initially, a RBC is placed in an isotonic NaCl solution (300 mOsm/L).  At point “1” the RBC is transferred to one liter of a 225 mOsm/L NaCl solution.  At point “2” one liter of 375 mOsm/L NaCl is added to the 225 mOsm/L NaCl solution.  Which of the following graphs correctly depicts the change in the volume of the RBC?
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

  • 10. 
    The following measurements were measured in a patient.  What is the patient’s estimated interstitial fluid volume and plasma volume in liters?             Body weight                      80 Kg           Hematocrit                        0.40           Plasma osmolarity              300 mOsm/L
    • A. 

      Interstitial fluid volume = 16 L; Plasma volume = 4 L

    • B. 

      Interstitial fluid volume = 12 L; Plasma volume = 4 L

    • C. 

      Interstitial fluid volume = 32 L; Plasma volume = 4 L

    • D. 

      Interstitial fluid volume = 16 L; Plasma volume = 6.5 L

    • E. 

      Interstitial fluid volume = 12 L; Plasma volume = 6.5 L

    • F. 

      Interstitial fluid volume = 32 L; Plasma volume = 6.5 L

  • 11. 
    A patient with edema is given 1.0 L of 2 g/L mannitol and 0.5L of 1 g/L Evans blue dye intravenously.  Two hours later the plasma concentration of mannitol and Evans blue dye are both 0.1 g/L and there was no loss of indicator in their urine.  What is the patient’s interstitial fluid volume?
    • A. 

      25 L

    • B. 

      20 L

    • C. 

      15 L

    • D. 

      5 L

    • E. 

      1 L

  • 12. 
    A 25 year old man completed the annual Dominican marathon in four hours. The average temperature during his run was 89 degrees Fahrenheit. He drank a small amount of bottled water during the run, then quickly drank 2 liters of bottled water after he crossed the finish line. The boxes below illustrate the relationship between volume (X-axis) and osmolarity (Y-axis) for the extracellular (ECF) and intracellular (ICF) fluid compartments.  In each diagram the boxes outlined with heavy black lines represent normal.  Which diagram most accurately describes the changes in osmolarity and volume in the ECF and ICF compartments of the runner after he completed the marathon and drank the two liters of water?
    • A. 

      1

    • B. 

      2

    • C. 

      3

    • D. 

      4

    • E. 

      5

  • 13. 
    You have erythrocytes soaking in two different solutions. The first solution is a 300 mosm\L Urea solution (urea has an osmotic coeffiecient of 0) . The second solution is a 300 mosm\L NaCl solution (NaCl has an osmotic coeffiecient of 1). What will happen to the cells in each of these solutions after equilibration? Cells in Urea Solution          Cells in NaCl solution
    • A. 

      Swell swell

    • B. 

      Swell shrink

    • C. 

      Shrink swell

    • D. 

      Shrink shrink

    • E. 

      No change swell

    • F. 

      No change shrink

    • G. 

      Swell no change

    • H. 

      Shrink no change

  • 14. 
    1 L of 12 g/L inulin and 100 ml of 10 g/L antipyrine are given to a patient intravenously.  Two hours later a blood sample is taken and the concentration of inulin and antipyrine in the plasma are both 1 g/L.  Given the patient has a hematocrit of 30% and there is no lose of the indicators in their urine, what is the patient’s extracellular fluid volume?
    • A. 

      1.0 L

    • B. 

      5.0 L

    • C. 

      10.0 L

    • D. 

      12.0 L

  • 15. 
    A woman weighing 60 kg is given 10 mg of T-1824 dye (Evans blue) intravenously.  Ten minutes later, a blood sample is obtained from another vein, and colorimetric analysis of the plasma shows the presence of 0.4 mg of T-1824 per 100 ml of plasma. Assume that the administered dye was evenly distributed throughout the plasma compartment by the end of the 10 minutes, and that no dye was lost from the plasma during this interval. The blood sample also showed that red blood corpuscles constitute 45% of whole blood—that is, the woman’s hematocrit ratio is 45%. What is this woman’s plasma volume and whole blood volume?     Plasma volume, L Whole Blood volume, L
    • A. 

      2.5 4.5

    • B. 

      2.5 5.5

    • C. 

      3.0 5.5

    • D. 

      3.0 6.6

    • E. 

      3.5 6.4