Bio1332 Biochemistry - Lecture Eighteen - Oxidative Phosphorylation

18 Questions | By Ellycrook | Last updated: Apr 8, 2021 | Total Attempts: 595

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Bio1332 Biochemistry - Lecture Eighteen - Oxidative Phosphorylation

 1. Understand the process of oxidative phosphorylation  2. Know the enzyme complexes that make up the electron transport chain  3. Understand how electron transfer is linked to proton pumping  4. Understand how the proton gradient is linked to ATP production

Questions and Answers

1.

Where in the mitochondria does oxidative phosphorylation occur?
2.

What is the electron yield so far (all the stages of aerobic respiration before oxidative phosphorylation)?
3.

Which of the following is true?
- A.
  
  Each carrier in the chain has lower free energy than the preceding member
- B.
  
  Each carrier in the chain has higher free energy than the preceding member
- C.
  
  Each carrier in the chain has the same free energy as the preceding member
4.

Electrons flow spontaneously along the chain.True or False?
- A.
  
  True
- B.
  
  False
5.

Please fill answer below:Electron-motive force is converted into a _______________ force, which is then converted into phosphoryl transfer potential.
6.

Name the first complex in the electron transfer chain.
7.

How many polypeptide chains does NADH-Q reductase consist of?
- A.
  
  34
- B.
  
  24
- C.
  
  12
- D.
  
  16
8.

Name the prosthetic groups found in NADH-Q reductase.
9.

Please fill answers below (separate answers with comma and space):The flow of two electrons from NADH to QH2 leads to the pumping of ______ H+ ions from the matrix into the _________________.The H+ can not diffuse back into the matrix, generating a _____________.
10.

Name the second complex in the chain.
11.

What happens at the second complex?
- A.
  
  FADH2 is oxidised and loses two electrons to coenzyme Q via Fe-S clusters
- B.
  
  FADH2 is oxidised and loses four electrons to coenzyme Q via Fe-S clusters
- C.
  
  FADH2 is oxidised and loses two electrons to coenzyme Q via FMNs
- D.
  
  FADH2 is oxidised and loses four electrons to coenzyme Q via FMNs
12.

Name the 3rd complex in the chain.
13.

Name the 4th complex in the chain.
14.

Please fill answer below:The only route for the protons to get back into the matrix from the intermembrane compartment is through ________________.
15.

"The flow of H+ ions / protons through ATP synthase is needed, because ATP cannot be formed without proton flow through the complex."True or False?
- A.
  
  True
- B.
  
  False
16.

Name an inhibitor of oxidative phosphorylation.
17.

Please fill answer below: The tight coupling of electron transport and oxidative phosphorylation can be disrupted by _____________. These allow protons to flow back across the membrane without going through ATP synthase. ‘Proton leak’

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Questions: 13 | Attempts: 11421 | Last updated: Oct 28, 2020