Anemias And Hemoglobinopathies

45 Questions | Total Attempts: 956

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Blood Quizzes & Trivia

Questions and Answers
  • 1. 
     small size RBC
    • A. 

      Microcytic

    • B. 

      Macrocytic

    • C. 

      Hypochromic

    • D. 

      Hyperchromic

    • E. 

      Normochromic

    • F. 

      Normocytic

  • 2. 
    Large size RBC
    • A. 

      Microcytic

    • B. 

      Macrocytic

    • C. 

      Hypochromic

    • D. 

      Hyperchromic

    • E. 

      Normochromic

    • F. 

      Normocytic

  • 3. 
    Less color in RBC
    • A. 

      Microcytic

    • B. 

      Macrocytic

    • C. 

      Hypochromic

    • D. 

      Hyperchromic

    • E. 

      Normochromic

    • F. 

      Normocytic

  • 4. 
    More color in RBC
    • A. 

      Microcytic

    • B. 

      Macrocytic

    • C. 

      Hypochromic

    • D. 

      Hyperchromic

    • E. 

      Normochromic

    • F. 

      Normocytic

  • 5. 
    Which of the following is not a cause of anemia?
    • A. 

      Decreased production of RBCs

    • B. 

      Space occupying lesions

    • C. 

      Increased destruction of RBCs

    • D. 

      Overproduction of RBCs

    • E. 

      Bone marrow poisons

    • F. 

      Chronic disease (i.e, uremia)

  • 6. 
    Pernicious anemia can be caused by which of the following? (check all that apply)
    • A. 

      B12 deficiency

    • B. 

      Lack of intrinsic factor

    • C. 

      Lack of absorption site

    • D. 

      Crohn's disease

    • E. 

      Atrophic gastritis

  • 7. 
    Macrocytic anemia caused by vitamin B12 and/or folate deficiency; interruption of DNA Synthesis
    • A. 

      Megaloblastic anemia

    • B. 

      Polycythemia

    • C. 

      Anemia of chronic disease

    • D. 

      Sickle cell anemia

  • 8. 
    The main cause of pernicious anemia is an autoimmune disease associated with decreased intrinsic factor due to autoantibodies (intrinsic factor carries Vitamin B12 to ileum for absorption)
    • A. 

      True

    • B. 

      False

  • 9. 
    Directed against, and destroys gastric parietal cells, so that they cannot make intrinsic factor
    • A. 

      Anti-parietal cell antibody

    • B. 

      Anti-intrinsic factor antibody

  • 10. 
    Directed against intrinsic factor
    • A. 

      Anti-parietal cell antibody

    • B. 

      Anti-intrinsic factor antibody

  • 11. 
    Both autoantibodies (anti-parietal cell antibody and anti-intrinsic factor antibody)  cause deficient intrinsic factor, and therefore malabsorption of vitamin B12
    • A. 

      True

    • B. 

      False

  • 12. 
    Which of the following is NOT a cause of megaloblastic anemia?
    • A. 

      "tea and toast" diet

    • B. 

      Pregnancy

    • C. 

      Chronic hemolytic anemia

    • D. 

      Alcoholism

    • E. 

      All of these cause megaloblastic anemia

  • 13. 
    Fish tapeworm can lead to competition for B12 and eventually cause megaloblastic anemia
    • A. 

      True

    • B. 

      False

  • 14. 
    There are neurologic deficits in Vitamin B12 deficiency and not in folate deficiency.
    • A. 

      True

    • B. 

      False

  • 15. 
    Iron deficiency
    • A. 

      Hypochromic microcytic anemia

    • B. 

      Normochromic normocytic anemia

    • C. 

      Normochromic macrocytic anemia

  • 16. 
    Anemia of chronic disease
    • A. 

      Hypochromic microcytic anemia

    • B. 

      Normochromic normocytic anemia

    • C. 

      Normochromic macrocytic anemia

  • 17. 
    In iron deficiency anemia, ferritin will be low and TIBC will be high
    • A. 

      True

    • B. 

      False

  • 18. 
    In anemia of chronic disease, iron stores may be high or normal, therefore ferritin will be high and TIBC will be low.
    • A. 

      True

    • B. 

      False

  • 19. 
    Things that occur with LOW IRON (check all that apply)
    • A. 

      Decreased ferritin

    • B. 

      Increased TIBC

    • C. 

      Increased ferritin

    • D. 

      Decreased TIBC

  • 20. 
    Things that occur with HIGH IRON (check all that apply)
    • A. 

      Decreased ferritin

    • B. 

      Increased TIBC

    • C. 

      Increased ferritin

    • D. 

      Decreased TIBC

  • 21. 
    For —iron deficiency anemia, the most sensitive test is bone marrow iron and the next best is serum ferritin
    • A. 

      True

    • B. 

      False

  • 22. 
    Which hemoglobin is increased with thalassemia?
    • A. 

      Hgb A

    • B. 

      Hgb F

    • C. 

      Hgb S

    • D. 

      Hgb SC

    • E. 

      Hgb C

  • 23. 
    Sickle cell - Equatorial Africa, malaria protection
    • A. 

      Hgb A

    • B. 

      Hgb F

    • C. 

      Hgb S

    • D. 

      Hgb SC

    • E. 

      Hgb C

  • 24. 
    West Africa- —Large spleen, many target cells (30%)
    • A. 

      Hgb A

    • B. 

      Hgb F

    • C. 

      Hgb S

    • D. 

      Hgb SC

    • E. 

      Hgb C

  • 25. 
    90% of cells are target cells
    • A. 

      Hgb A

    • B. 

      Hgb F

    • C. 

      Hgb S

    • D. 

      Hgb SC

    • E. 

      Hgb C

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