Abo_shousha_cns_quiz_17_antipsychotics

5 Questions | Total Attempts: 103

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Abo_shousha_cns_quiz_17_antipsychotics

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Questions and Answers
  • 1. 
    Which of the following antipsychotic agents is used in combination with an opioid drug fentanyl inneuroleptanalgesia?
    • A. 

      Haloperidol

    • B. 

      Droperidol

    • C. 

      Chlorpromazine

    • D. 

      Clozapine

  • 2. 
    Tardive dyskinesia is the result of:
    • A. 

      Degeneration of dopaminergic and cholinergic fibers

    • B. 

      Hyperactive dopaminergic state in the presence of dopamine blockers

    • C. 

      Degeneration of histaminergic fibers

    • D. 

      Supersensitivity of cholinergic receptors in the caudate-putamen

  • 3. 
    Hyperprolactinemia is caused by blockade of dopamine in:
    • A. 

      The pituitary

    • B. 

      The chemoreceptor trigger zone of the medulla

    • C. 

      The extrapiramidal system

    • D. 

      The mesolimbic and mesofrontal systems

  • 4. 
    Typical antipsychotic drugs:
    • A. 

      Strongly block postsynaptic D2 receptor

    • B. 

      Stimulate postsynaptic D2 receptor

    • C. 

      Block NMDA receptor

    • D. 

      Block NMDA receptor

  • 5. 
    The major limitation in the use of clozapine for treatment of schizophrenia is:
    • A. 

      Production of hyperprolactinemia

    • B. 

      Its inability to benefit negative symptoms of schizophrenia

    • C. 

      High incidence of extra pyramidal side effects

    • D. 

      Its potential to cause agranulocytosis