Can You Pass This Antidepressant Quiz

Explanation
Administration of an MAO inhibitor would most likely cause changes in the CNS concentration of norepinephrine. MAO inhibitors work by blocking the enzyme monoamine oxidase, which is responsible for breaking down norepinephrine. By inhibiting this enzyme, the concentration of norepinephrine in the CNS would increase. Acetylcholine, histamine, and glutamate are not directly affected by MAO inhibitors.

Explanation
Fluoxetine is primarily used for treating endogenous depression. Endogenous depression is a type of depression that is believed to be caused by internal factors, such as chemical imbalances in the brain, rather than external factors like life events or stress. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that works by increasing the levels of serotonin in the brain, which helps to improve mood and reduce symptoms of depression. It is not commonly used for treating OCD, morbid obesity, or anxiety.

Explanation
Imipramine is a tricyclic antidepressant that can cause orthostatic hypotension as a side effect. Orthostatic hypotension refers to a drop in blood pressure when changing positions, such as standing up from a sitting or lying position. This can lead to symptoms like dizziness, lightheadedness, and even fainting. Imipramine can affect the autonomic nervous system, which helps regulate blood pressure, leading to this side effect. It is important to monitor patients taking imipramine for any signs of orthostatic hypotension and adjust the dosage if necessary.

Explanation
Antidepressants are commonly used in the treatment of various mental health disorders, including severe anxiety disorder, post-traumatic stress disorder (PTSD), and endogenous depression. These medications help to regulate neurotransmitters in the brain, such as serotonin, which can improve mood and alleviate symptoms associated with these conditions. Therefore, the correct answer is "All of the above," as antidepressants can be used therapeutically for all three mentioned disorders.

Explanation
Fluoxetine is an antidepressant that belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs). One of the common side effects of fluoxetine is insomnia, which refers to difficulty falling asleep or staying asleep. This side effect may occur in some individuals who take fluoxetine as it affects the levels of serotonin in the brain, which can disrupt the normal sleep-wake cycle. Therefore, insomnia is a known side effect of fluoxetine.