How much do you know about antidepressants? This quiz can help test your knowledge. Antidepressants work on certain neurotransmitters in the brain. These neurotransmitters mainly include serotonin and norepinephrine, both of which play a role in boosting your mood. Antidepressants can help alleviate the signs of depression, low mood, irritability, and anxiety. If you want to learn more about antidepressants, this quiz can be of service. Take this amazing quiz and prepare to get happy.
Reactive - biochemical disorder in brain; endogenous - genetic cause
Reactive - response to death; exogenous - adverse effect of some medication
Reactive - response to circumstance; endogenous - biochemical disorder
Reserpine (inhibits brain storage of noradrenaline and serotonin) causes depression
Reserpine (inhibits brain storage of adrenaline, histamine and acetylcholine) is a treatment for depression
Amphetamine (causes release of noradrenaline) has no effect in depressed patients
Cocaine (inhibits reuptake of noradrenaline) treats depression
Urinary excretion of the serotonin metabolite 5-HIAA is unchanged in depressed patients
Urinary and cerebral spinal fluid concentrations of the noradrenaline metabolite MOPEG are reduced by 25% in depressed patients
Dibenzazepines; dibenzocycloheptenes
Hydrazines; propargylamines
Piperazines; piperidines
Competitive antagonist for inhibitors of neurotransmitters in synaptic cleft, meaning more re-uptake, so neurotransmitters exert effects for shorter lengths of time
Non-competitive agonist for re-uptake of neurotransmitters in synaptic cleft, meaning no re-uptake, so neurotransmitters exert effects for longer
Competitive antagonist for re-uptake of neurotransmitters in synaptic cleft, meaning no re-uptake, so neurotransmitters exert effects for longer
Muscarinic; histaminic; B-adrenoceptors
Nicotinic; adrenergic (a and b)
Histaminic; nicotinic; a-adrenoceptors
Catalyse breakdown of noradrenaline and serotonin
Inhibit breakdown of noradrenaline and serotonin
Inhibit breakdown of adrenaline and serotonin
Decreased absorption of vasoactive amines from diet; too many so pathway becomes saturated, build up; can lead to cerebral hemorrhage and death
Absorption of vasoactive amines from diet, cannot be broken down, build up; can lead to cerebral hemorrhage and death
Absorption of vasoactive amines from diet, cannot be broken down, build up; can lead to high intercranial pressure and fitting
Typical, atypical
Dibenzapines, dibenzocycloheptenes
Hydrazines, propargylamines, cyclopropylamines, reversible inhibitors
Selectively block serotonin reuptake into the pre-synaptic cell
Non-selectively block serotonin and noradrenaline reuptake into the pre-synaptic cell
Selectively increase affinity of the post-synaptic receptors for serotonin
Very common; supraventricular tachycardia; high intercranial pressure and abdominal cramps
An adverse effect; bradycardia and sweating; fitting and liver failure
Technically a form of poisoning; tachycardia and shivering; seizures and renal failure
They are administered as pro-drugs with exteremely long half-lives
Autoreceptors quickly become desensitised to newly increased levels of serotonin; 2-3 weeks is the time taken for more to be synthesised
They are metabolised very slowly by P450 enzymes
Atropine-like side effects
Alpha-block-like side effects
Suicidal thoughts
Evening Primrose Oil; L-Dopa, the precursor to serotonin
St John's Wort; L-Trytophan, the precursor to serotonin
St John's Wort; L-Dopa, the precursor to dopamine
Lithium esters; preventing fluctuations in bipolar depression
Lithium anhydride; stabilising the depressive phase in bipolar depression
Lithium carbonate; stabilising the manic phase in bipolar depression
Wait!
Here's an interesting quiz for you.