Pharmaceutics Quiz - Questions And Answers: Test Your Knowledge
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Unequal distribution of color on a tablet, refers to
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Picking
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Mottling
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Capping
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Sticking
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Pharmaceutics, a captivating field, revolves around the study of medicines and their impact on the human body. Our Pharmaceutics Quiz Questions and Answers have been carefully crafted to provide both entertainment and education, challenging your comprehension of fundamental medicinal principles. This quiz serves as a valuable tool for examination preparation, encouraging you to test your grasp of pharmaceutical essential concepts. See more
Approach this quiz with care and concentration, as it can significantly aid in your academic pursuits. Understanding the intricacies of pharmaceutics is pivotal for healthcare professionals and researchers, ensuring the safe and effective application of medications.
So, immerse yourself in the quiz, confront your knowledge, and remain steadfast in your commitment to mastering this critical scientific domain. Best of luck on your journey of pharmaceutical exploration, and may your dedication to learning be as rewarding as it is enlightening! Keep up the diligent studying!
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- 2.
Enteric coated tablet is disintegrated in
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Stomach
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Liver
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Intestine
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Mouth
Correct Answer
A. IntestineExplanation
Enteric coated tablets are specifically designed to resist disintegration in the stomach and instead dissolve in the intestine. This is because certain medications can be irritating to the stomach lining or may be destroyed by stomach acid. The enteric coating allows the tablet to pass through the stomach without disintegrating, and only starts to dissolve once it reaches the more neutral pH environment of the intestine. This ensures that the medication is released in the appropriate location for absorption into the bloodstream.Rate this question:
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- 3.
ENO is the example of?
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Effervescent granules
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Dry sealed sachet
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Tablet triturate
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Powder
Correct Answer
A. Effervescent granulesExplanation
ENO is an example of effervescent granules. Effervescent granules are a type of pharmaceutical formulation that contain a mixture of active ingredients and effervescent agents. When these granules come into contact with water, they release carbon dioxide gas, causing the mixture to fizz and dissolve. ENO is a popular antacid that is commonly used to relieve symptoms of indigestion and heartburn. It is available in the form of effervescent granules that are dissolved in water before consumption.Rate this question:
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- 4.
Match the following in the correct combination 1. Capping (P) Separation of a tablet into 2 or more layers 2. Lamination (Q) Unequal distribution of color on a tablet 3. Mottling (R) Separation of top/bottom crowns of a tablet 4. Sticking (S) Adherence of tablet material to the die wall
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2-P, 3-Q, 1-R, 4-S
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1-P, 2-Q, 3-R, 4-S
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3-P, 1-Q, 2-R, 4-S
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4-P, 1-Q, 3-R, 2-S
Correct Answer
A. 2-P, 3-Q, 1-R, 4-SExplanation
Capping refers to the separation of a tablet into 2 or more layers, which matches with option 2. Lamination refers to the unequal distribution of color on a tablet, which matches with option 3. Mottling refers to the separation of top/bottom crowns of a tablet from the main body, which matches with option 1. Sticking refers to the adherence of tablet material to the die wall, which matches with option 4. Therefore, the correct combination is 2-P, 3-Q, 1-R, 4-S.Rate this question:
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- 5.
Which of the following flavor is used in a formulation containing sour taste?
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Wild cherry
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Vanilla
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Citrus
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Chocolate
Correct Answer
A. CitrusExplanation
Citrus flavor is used in a formulation containing sour taste because citrus fruits like lemons, oranges, and limes have a naturally sour taste. Adding citrus flavor to a formulation can help to enhance the sourness and provide a tangy flavor profile. Wild cherry, vanilla, and chocolate flavors do not have a sour taste, making them unsuitable for a formulation requiring a sour flavor.Rate this question:
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- 6.
Which of these is responsible for sticking?
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Excessive moisture
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Low moisture
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Both
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None
Correct Answer
A. Excessive moistureExplanation
Excessive moisture is responsible for sticking. When there is too much moisture present, it can cause surfaces or objects to stick together. This is because the excess moisture creates a barrier between the two surfaces, causing them to adhere to each other. This can be seen in various situations, such as when wet paper sticks together or when humid weather causes doors or windows to become difficult to open or close.Rate this question:
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- 7.
Chewable tablet contains these base
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Mannitol
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Glucose
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Lactose
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None
Correct Answer
A. MannitolExplanation
The chewable tablet contains Mannitol as one of its base ingredients.Rate this question:
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- 8.
Which statement is not correct?
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Buccal routes avoids first pass metabolism
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Parenteral route avoids first pass metabolism
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Sublingual route avoids first pass metabolism
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Oral route avoids first pass metabolism
Correct Answer
A. Oral route avoids first pass metabolismExplanation
The statement "Oral route avoids first pass metabolism" is not correct. The oral route does not avoid first pass metabolism. When a drug is taken orally, it is absorbed through the gastrointestinal tract and enters the liver before reaching the systemic circulation. In the liver, the drug may undergo metabolism by enzymes, which can significantly reduce the bioavailability of the drug. This is known as first pass metabolism. Therefore, the correct answer is the statement "Oral route avoids first pass metabolism."Rate this question:
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- 9.
Diclofenac tablet with CAP has been administered to a patient. Where do you expect the drug to be released?
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Stomach
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Oral cavity
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Small intestine
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Liver
Correct Answer
A. Small intestineExplanation
When a diclofenac tablet with CAP (controlled-release) is administered, the drug is expected to be released in the small intestine. This is because controlled-release formulations are designed to deliver the drug slowly and steadily over a prolonged period of time. The small intestine is an ideal site for drug release as it has a large surface area for absorption and a longer transit time compared to the stomach or oral cavity. Additionally, the small intestine contains enzymes and bile salts that aid in the absorption of drugs, making it an optimal location for drug release.Rate this question:
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- 10.
In a formulation development laboratory, you have to formulate an oral dosage form containing olive oil, vitamin A and water. Select one of the appropriate labeling directions
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Keep in the refrigerator
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No preservatives added
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Schedule ‘G’ drug
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Shake well before use.
Correct Answer
A. Shake well before use.Explanation
The correct answer is "Shake well before use." This direction is appropriate because the oral dosage form contains olive oil, vitamin A, and water, which may separate or settle over time. By shaking the product well before use, it ensures that the ingredients are evenly distributed and the dosage form is properly mixed before consumption.Rate this question:
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- 11.
In the tablet coating process, inadequate spreading of coating solution before drying causes
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Orange peel effect
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Sticking effect
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Blistering effect
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Picking effect
Correct Answer
A. Orange peel effectExplanation
The inadequate spreading of the coating solution before drying in the tablet coating process can lead to the orange peel effect. This effect refers to the appearance of a rough, bumpy texture on the tablet surface, resembling the texture of an orange peel. It occurs when the coating solution does not spread evenly across the tablet surface, resulting in an uneven drying process. This can be caused by factors such as improper spray technique, high viscosity of the coating solution, or inadequate air flow in the coating equipment.Rate this question:
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- 12.
Flow rate of granules from the hopper can be improved by adding
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Disintegrant
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Glidant
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Binder
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Lubricant
Correct Answer
A. GlidantExplanation
Adding a glidant to the granules in the hopper can improve the flow rate. A glidant is a substance that reduces friction between particles, allowing them to flow more easily. By reducing the interparticle friction, the granules can move more freely through the hopper, resulting in an improved flow rate. This can be particularly beneficial in processes where a consistent and efficient flow of granules is required, such as in pharmaceutical manufacturing or bulk material handling.Rate this question:
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- 13.
Durability of a tablet to combined effects of shock & abrasion is evaluated by using
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Hardness tester
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Disintegration test apparatus
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Friabilator
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Screw guage
Correct Answer
A. FriabilatorExplanation
The correct answer is Friabilator because a friabilator is specifically designed to measure the durability of tablets by subjecting them to rotational forces and abrasion. It simulates the conditions tablets may encounter during transportation and handling. The tablets are placed in a drum that rotates, causing them to collide with each other and the walls of the drum. The amount of tablet weight loss is then measured, indicating the level of fragility and resistance to abrasion. This test helps determine if the tablet can withstand shocks and abrasion without breaking or crumbling.Rate this question:
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- 14.
Tablet granules are dried by one of the followings
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Drum dryer
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Fluidized bed Dryer
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Spary dryer
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Freeze dryer
Correct Answer
A. Fluidized bed DryerExplanation
Fluidized bed dryers are commonly used for drying tablet granules. In this process, the granules are suspended and fluidized in a stream of hot air, allowing for efficient drying and uniform moisture removal. The fluidized bed dryer offers advantages such as high drying rates, good heat transfer, and gentle handling of the granules, making it a suitable choice for drying pharmaceutical products like tablet granules. This method ensures that the granules are dried effectively and meet the required specifications for further processing.Rate this question:
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- 15.
Aerosil is used as
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Glidant
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Lubricant
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Antiadherant
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None
Correct Answer
A. GlidantExplanation
Aerosil is commonly used as a glidant in various industries. A glidant is a substance that is added to powders to improve their flow properties and reduce their tendency to stick to surfaces. Aerosil, which is a brand name for fumed silica, has excellent gliding properties and is often used in pharmaceuticals, cosmetics, and food processing to enhance the flowability of powders during manufacturing and packaging processes. It helps prevent clumping and ensures uniform distribution, making it easier to handle and process powders effectively.Rate this question:
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- 16.
Seal coating is done by using
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Shellac
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Acacia
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Gelatin
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None
Correct Answer
A. ShellacExplanation
Seal coating is a process used to protect and enhance the appearance of surfaces, such as wood or concrete. Shellac is a commonly used material for seal coating due to its excellent adhesive properties and ability to provide a durable and glossy finish. It forms a protective layer that helps to prevent damage from moisture, UV rays, and general wear and tear. Acacia and gelatin are not typically used for seal coating, making shellac the most suitable option.Rate this question:
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- 17.
Foam stability is measured by
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IR
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UV
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Rotational Viscometers
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All
Correct Answer
A. Rotational ViscometersExplanation
Rotational viscometers are used to measure the foam stability. These instruments are designed to measure the viscosity of liquids, which is an important factor in determining the stability of foam. By measuring the viscosity, rotational viscometers can provide information about the resistance of the foam to flow and deformation. This helps in assessing the stability of the foam and its ability to maintain its structure over time. Therefore, the correct answer is rotational viscometers.Rate this question:
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- 18.
The most commonly used humectants in tooth paste includes
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Glycerol
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Sorbitol
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Both A & B
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None of these
Correct Answer
A. Both A & BExplanation
The correct answer is "Both A & B." Glycerol and sorbitol are commonly used humectants in toothpaste. Humectants are ingredients that help to retain moisture and prevent the toothpaste from drying out. Glycerol and sorbitol have hygroscopic properties, meaning they attract and hold onto water molecules, keeping the toothpaste moist and easy to squeeze out of the tube. These humectants also contribute to the smooth texture and pleasant taste of toothpaste.Rate this question:
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- 19.
Tablets, which are placed between cheek and teeth, are known as
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Buccal
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Sublingual
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Lozenges
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Troches
Correct Answer
A. BuccalExplanation
Tablets that are placed between the cheek and teeth are known as buccal tablets. Buccal administration involves placing medication in the buccal cavity, where it dissolves and is absorbed through the buccal mucosa. This route of administration allows for direct absorption into the bloodstream, bypassing the digestive system and liver metabolism. Buccal tablets are designed to slowly release the medication, providing a controlled and sustained release of the drug.Rate this question:
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- 20.
pH of the small intestine is
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1-2
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3-4
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5-6
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6-7.4
Correct Answer
A. 6-7.4Explanation
The pH of the small intestine is 6-7.4. This is because the small intestine secretes bicarbonate ions to neutralize the acidic chyme that enters from the stomach. The bicarbonate ions raise the pH level in the small intestine to create a more alkaline environment, which is optimal for the activity of digestive enzymes and absorption of nutrients.Rate this question:
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- 21.
Empty capsule has moisture content in the range of
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60%
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13%-16%
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50%- 70%
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30%
Correct Answer
A. 13%-16%Explanation
Empty capsules typically have a moisture content in the range of 13%-16%. This moisture content is important because it affects the stability and integrity of the capsule. If the moisture content is too high, the capsule may become soft and lose its shape, making it difficult to handle and fill with medication. On the other hand, if the moisture content is too low, the capsule may become brittle and prone to cracking. Therefore, maintaining a moisture content within the range of 13%-16% ensures that the empty capsule remains stable and suitable for use in the pharmaceutical industry.Rate this question:
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- 22.
Carr’s index is used to determine
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Elasticity
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Particle size
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Sieve size
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Flowability
Correct Answer
A. FlowabilityExplanation
Carr's index is used to determine the flowability of a material. It is a measure of the compressibility and flow properties of a powder or granular material. A higher Carr's index indicates poor flowability, while a lower index suggests better flowability. By measuring the Carr's index, one can assess the ability of a material to flow freely and smoothly, which is important in various industries such as pharmaceuticals, food processing, and powder handling.Rate this question:
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- 23.
Which of the following routes of administration is MOST likely to result in the first-pass effect?
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Intravenous
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Sublingual
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Oral
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Transdermal
Correct Answer
A. OralExplanation
The first-pass effect is a phenomenon where a drug's concentration is significantly reduced before it reaches systemic circulation. This is because the drug is metabolized by the liver after being absorbed from the gastrointestinal tract. Oral administration is the most common route to result in the first-pass effect.Rate this question:
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- 24.
Which of the following is not added in lozenges?
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Sweetner
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Binder
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Disintegrant
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All
Correct Answer
A. DisintegrantExplanation
Disintegrants are substances that help the lozenges break down and dissolve in the mouth. They are added to promote the release of the active ingredients. Sweeteners, binders, and other excipients are commonly used in the formulation of lozenges to enhance taste, texture, and stability. Lozenges dissolve slowly. Therefore, disintegrants are not added in lozenges.Rate this question:
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- 25.
The equipment listed P-T is used for the identification of properties of aerosol mentioned below. Match them. 1. Particle size determination 2. Identification of propellants 3. Stability of foam 4. Flash point (P) Pycnometer (Q) Rotaional viscometer (R) Tag open cap apparatus (S) IR spectroscopy (T) Cascade impaction
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1-P, 2-Q, 3-R, 4-S
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1-Q, 2-P, 3-S, 4-T
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1-T, 2-S, 3-Q, 4-R
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1-R, 2-S, 3-P, 4-Q
Correct Answer
A. 1-T, 2-S, 3-Q, 4-RExplanation
The equipment listed P-T is used for the identification of properties of aerosol mentioned below. The cascade impaction (T) is used for particle size determination. IR spectroscopy (S) is used for the identification of propellants. The rotational viscometer (Q) is used for stability of foam. The tag open cap apparatus (R) is used for flash point determination.Rate this question:
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- 26.
The identification of propellants in pharmaceutical aerosols is carried out by (P) Gas chromatography (R) Pycnometer (Q) Tag open cup apparatus (S) IR spectrophotometer
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P, Q
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P, S
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Q, R
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R, S
Correct Answer
A. P, SExplanation
Gas chromatography and IR spectrophotometer are commonly used techniques for the identification of propellants in pharmaceutical aerosols. Gas chromatography separates the components of a mixture based on their different volatilities, allowing for the identification and quantification of propellants. IR spectrophotometer, on the other hand, measures the absorption of infrared radiation by the propellants, providing information about their chemical structure and allowing for their identification. Therefore, the correct answer is P, S.Rate this question:
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- 27.
Given below are equipment used in the manufacture of following products P-T. Match them and find out correct answer 1. Zenasi (P) Tablet granules 2. Hepa filter (Q) Tablet coating 3. Chilsonator (R) Emulsion 4. Accela cota (S) Injectables (T) Capsule
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1-p, 2-s, 3- p, 4-q
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1-P, 2-Q, 3-S, 4-R
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(c) 1-T, 2-R, 3-Q, 4-P
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1-S, 2-R, 3-P, 4-Q
Correct Answer
A. 1-p, 2-s, 3- p, 4-qExplanation
Zenasi could align with granulation (P).
Hepa Filter ensures a sterile environment, necessary for Injectables (S).
Chilsonator performs dry granulation, creating Tablet Granules (P).
Accela Cota is designed for Tablet Coating (Q).Rate this question:
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- 28.
Colloidal silica (AEROSIL®) is used as
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Diluent
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Glidant
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Disifectant
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Lubricant
Correct Answer
A. GlidantExplanation
Colloidal silica (AEROSIL®) is used as a glidant. A glidant is a material that is added to powders to improve their flowability and reduce the friction between particles. It helps to prevent the powder from clumping or sticking together, allowing for easier and more uniform filling of capsules or tablets. Colloidal silica has excellent gliding properties and is commonly used in pharmaceutical and cosmetic industries to enhance the flow characteristics of powders.Rate this question:
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- 29.
Select the equation that gives the rate of drug dissolution from a tablet
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Fick’s law
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Henderson-Hasselbatch equation
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Noyes-Whitney equation
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Michelis Menton equation
Correct Answer
A. Noyes-Whitney equationExplanation
The Noyes-Whitney equation is used to calculate the rate of drug dissolution from a tablet. It states that the rate of dissolution is directly proportional to the surface area of the tablet and the concentration difference between the drug in the tablet and its surrounding medium, and inversely proportional to the thickness of the diffusion layer. This equation is commonly used in pharmaceutical sciences to understand and predict the release of drugs from solid dosage forms.Rate this question:
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- 30.
Which of the following substance is used as mucoadhesive
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Acacia
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Sodium CMC
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Burnt sugar
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Saccharin
Correct Answer
A. Sodium CMCExplanation
Sodium CMC (Sodium Carboxymethylcellulose) is used as a mucoadhesive substance. Mucoadhesive substances are those that can stick to the mucous membranes, such as those in the mouth or nasal cavity, for an extended period of time. Sodium CMC is commonly used in pharmaceutical and oral care products due to its ability to adhere to the mucous membranes, providing sustained release of medication or prolonged contact time for oral products. Acacia, burnt sugar, and saccharin do not possess mucoadhesive properties.Rate this question:
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- 31.
Which of the following is NOT a factor influencing the dissolution rate of a solid drug in a liquid?
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Viscosity of the liquid.
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Temperature of the liquid.
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Molecular weight of the drug.
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Packaging material of the drug.
Correct Answer
A. Packaging material of the drug.Explanation
The dissolution rate refers to how quickly a solid drug dissolves in a liquid to become a solution. Several factors influence this process:
Particle size: Smaller particles dissolve faster due to increased surface area.
Viscosity: Thicker liquids slow down the dissolution process.
Temperature: Higher temperatures generally increase the dissolution rate.
Molecular weight: This can influence the drug's solubility and, therefore, its dissolution rate.
However, the packaging material does not directly affect the dissolution rate. While packaging is important for stability and storage, it doesn't alter the physical and chemical properties that govern dissolution.Rate this question:
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- 32.
Polyvinyl acetate phthalate is used for
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Sugar coating
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Film coating
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Enteric coating
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None of these
Correct Answer
A. Enteric coatingExplanation
Polyvinyl acetate phthalate is used for enteric coating. Enteric coating is a process in which a protective layer is applied to a tablet or capsule to prevent it from dissolving in the stomach. This coating allows the medication to pass through the stomach intact and release in the intestines, where it is absorbed. Polyvinyl acetate phthalate is commonly used in enteric coating because it provides a barrier that is resistant to the acidic environment of the stomach.Rate this question:
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- 33.
What is the primary role of a compounding pharmacy in the field of healthcare?
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To manufacture large quantities of standard medications for distribution to retail pharmacies.
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To provide specialized medications tailored to individual patient needs when commercially available drugs are not suitable.
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To conduct clinical trials for new pharmaceutical products.
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To dispense over-the-counter medications and supplements.
Correct Answer
A. To provide specialized medications tailored to individual patient needs when commercially available drugs are not suitable.Explanation
The primary role of a compounding pharmacy in the field of healthcare is to prepare customized medications for patients based on specific requirements. This is often necessary when commercially available medications do not meet the patient's needs due to factors such as allergies, dosage forms, or ingredient preferences. Compounding pharmacies work closely with healthcare providers to create medications that are not readily available in standard form, ensuring that patients receive the most suitable and effective treatment.Rate this question:
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- 34.
Which of the following is a synthetic adhesive?
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PVP
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MC
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HPMC
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HPC
Correct Answer
A. PVPExplanation
PVP is a synthetic adhesive because it stands for polyvinylpyrrolidone, which is a polymer that is commonly used as an adhesive in various industries. It has excellent adhesive properties and is known for its ability to bond different materials together. PVP is widely used in applications such as paper and packaging, woodworking, and medical adhesives. It is a popular choice due to its strong bonding strength, versatility, and resistance to moisture and chemicals.Rate this question:
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- 35.
In dissolution test, flask is maintained at
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37oC ± 0.5oC
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37oC ± 1oC
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37oC ± 0.6oC
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37oC ± 1.5Oc
Correct Answer
A. 37oC ± 0.5oCExplanation
The correct answer is 37°C ± 0.5°C. In dissolution testing, it is important to maintain a specific temperature to ensure consistent and accurate results. The range of ± 0.5°C allows for slight temperature fluctuations while still maintaining the desired temperature of 37°C. This range ensures that the dissolution process is carried out under controlled conditions, minimizing any potential impact on the results.Rate this question:
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- 36.
Which one of the following propellant is used in the aerosol for oral use?
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Propane
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Oxygen
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Methane
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Tri chloro Monofluoro methane
Correct Answer
A. Tri chloro Monofluoro methaneExplanation
Tri chloro Monofluoro methane, also known as chlorofluorocarbon (CFC-11), is commonly used as a propellant in aerosols for oral use. It is a colorless gas that is non-toxic and non-flammable, making it suitable for use in medical and pharmaceutical products. CFC-11 has good solubility in liquids and provides a consistent and controlled release of the medication from the aerosol container. It is often used in inhalers, throat sprays, and other oral aerosol medications.Rate this question:
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- 37.
Aerosol packaging container must resist pressure of
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500 psig
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140-180 psig
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40 psig
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20 psig
Correct Answer
A. 140-180 psigExplanation
The correct answer is 140-180 psig because aerosol packaging containers need to be able to withstand a certain amount of pressure. The range of 140-180 psig is within the acceptable pressure range for these containers. This ensures that the container will not burst or leak when it is being used or stored.Rate this question:
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- 38.
The correct non-ionic surfactant used as a penetration enhancer in the preparation of mucoadhasives
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Oleic acid
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Tween 80
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Glycerol
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Propylene glycol
Correct Answer
A. Tween 80Explanation
Tween 80 is a correct non-ionic surfactant used as a penetration enhancer in the preparation of mucoadhesives. It is commonly used in pharmaceutical formulations due to its ability to increase drug absorption through mucosal membranes. Tween 80 acts by reducing the surface tension of the mucosal membrane, allowing for better contact and penetration of drugs. It also enhances the solubility and stability of drugs in the formulation. Overall, Tween 80 is an effective choice for improving drug delivery and bioavailability in mucoadhesive preparations.Rate this question:
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- 39.
What is the use of methyl cellulose in ophthalmic solutions?
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To protect eye
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To increase ocular contact time
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To decrease ocular contact time
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As preservative
Correct Answer
A. To increase ocular contact timeExplanation
Methyl cellulose is used in ophthalmic solutions to increase ocular contact time. This means that it helps the solution to stay on the surface of the eye for a longer period of time, allowing for better absorption and effectiveness of the medication. By increasing the contact time, methyl cellulose ensures that the solution remains in contact with the eye for a sufficient duration, improving its therapeutic benefits.Rate this question:
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- 40.
The disintegration time for sugar coated tablets is
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30 min.
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45 min.
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60 min.
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75 min.
Correct Answer
A. 60 min.Explanation
The disintegration time for sugar coated tablets is 60 minutes. This means that it takes approximately 60 minutes for the sugar coating on the tablets to dissolve and for the tablet to break apart into smaller pieces. This is an important factor to consider for patients who may have difficulty swallowing whole tablets, as a longer disintegration time may make it easier for them to consume the medication.Rate this question:
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- 41.
Some possible causes are mentioned in P-T, for the following defects during the film coating of tablets. Match them 1. Chipping 2. Cracking 3. Orange peel 4. Blistering (P) Poor spreading during spraying (Q) Over heating during spraying (R) Higher internal stresses in film (S) Excessive coating process (T) Precipitation of polymer due to high temperature/poor solvent
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1-S, 2-R, 3-P, 4-Q
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1-T, 2-S, 3-R, 4-P
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1-P, 2-Q, 3-R, 4-S
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1-R, 2-P, 3-Q, 4-T
Correct Answer
A. 1-S, 2-R, 3-P, 4-QExplanation
The correct answer is 1-S, 2-R, 3-P, 4-Q. Chipping is caused by excessive coating process (S), cracking is caused by higher internal stresses in the film (R), orange peel is caused by poor spreading during spraying (P), and blistering is caused by over heating during spraying (Q).Rate this question:
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- 42.
A retardant material that forms a hydrophilic matrix in the formulation of matrix tablets is
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HPMC
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CAP
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Polyethylene
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Carnaubaa wax
Correct Answer
A. HPMCExplanation
HPMC (Hydroxypropyl methylcellulose) is a retardant material that forms a hydrophilic matrix in the formulation of matrix tablets. It is a cellulose derivative that swells and forms a gel-like matrix when it comes into contact with water. This matrix controls the release of the active pharmaceutical ingredient (API) from the tablet, allowing for a sustained and controlled release over time. HPMC is commonly used in pharmaceutical formulations due to its biocompatibility, stability, and ability to provide controlled drug release.Rate this question:
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- 43.
Friabilator is operated at
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100 RPM
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75 RPM
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50 RPM
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25 RPM
Correct Answer
A. 25 RPMExplanation
The correct answer is 25 RPM. The friabilator is operated at this speed to measure the friability of tablets. Friability refers to the tendency of tablets to crumble or break when subjected to mechanical stress. A lower RPM is preferred to ensure that the tablets are not excessively stressed, which could lead to inaccurate results. Therefore, operating the friabilator at 25 RPM helps to maintain the integrity of the tablets while still providing a reliable measurement of their friability.Rate this question:
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- 44.
Capping is prevented by using one of the following punches
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Flat
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Circular
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Square
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Rectangular
Correct Answer
A. FlatExplanation
Capping, which refers to the formation of a raised area around the tablet edge, can be prevented by using a flat punch. This type of punch ensures that the compression force is evenly distributed across the tablet, resulting in a uniform and smooth surface. The flat punch helps to maintain the integrity of the tablet and prevents any excess material from being pushed to the edges, thus avoiding the occurrence of capping.Rate this question:
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- 45.
Which of the following is a common excipient used as a binder in tablet formulations?
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Magnesium stearate
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Lactose
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Povidone
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Talc
Correct Answer
A. PovidoneExplanation
Think of making a pill like baking a cake. You need the right ingredients to hold it all together! Povidone is like the "glue" that binds the powdered drug and other stuff in a pill, making it a solid tablet. Other ingredients have different jobs: lactose adds bulk, magnesium stearate helps it slide out of the machine, and sodium starch glycolate helps it break apart in your stomach. But povidone is the key to keeping that pill from crumbling.Rate this question:
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- 46.
A retardant material that forms a hydrophilic matrix in the formulation of matrix tablets is
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HPMC
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CAP
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Polyethylene
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Carnuba wax
Correct Answer
A. HPMCExplanation
HPMC (Hydroxypropyl methylcellulose) is a retardant material commonly used in the formulation of matrix tablets. It forms a hydrophilic matrix when mixed with other excipients, allowing for controlled release of the active ingredient. This matrix swells upon contact with water, creating a gel-like barrier that slows down the dissolution of the drug. This sustained release mechanism helps to maintain therapeutic drug levels in the body over an extended period of time. HPMC is widely used in pharmaceutical formulations due to its biocompatibility, stability, and versatility in controlling drug release profiles.Rate this question:
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- 47.
Lanolin is
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Hydrocarbon
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An adsorption base
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Water removable
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None of these
Correct Answer
A. An adsorption baseExplanation
An ointment base refers to the vehicle or carrier substance in which the active ingredient of an ointment is dispersed. Lanolin is a commonly used ointment base that is derived from sheep's wool. It has excellent emollient properties and provides a protective barrier on the skin. The term "adsorption base" refers to an ointment base that has the ability to adsorb water or other substances onto its surface. Lanolin is known for its adsorptive properties, making it an appropriate choice for an adsorption base. Therefore, the correct answer is "Adsorption base."Rate this question:
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- 48.
Green bone is a source of
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Type A gelatin
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Type B gelatin
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Both
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None
Correct Answer
A. Type B gelatinExplanation
Green bone is a source of Type B gelatin.Rate this question:
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- 49.
Which one of these is tablet granulator?
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Accella cota
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Zanasi
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Chilsonator
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None of these
Correct Answer
A. ChilsonatorExplanation
The Chilsonator is a tablet granulator.Rate this question:
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Nov 07, 2024Quiz Edited by
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Nov 21, 2019Quiz Created by
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