Trophoblastic Disease Aka Molar Pregnancies / Ob/GYN

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Trophoblastic Disease Aka Molar Pregnancies / Ob/GYN - Quiz

OB / GYN Quiz


Questions and Answers
  • 1. 
    Molar pregnancies may be complete, partial, invasive, or malignant.
    • A. 

      True

    • B. 

      False

  • 2. 
    Molar pregnancies are thought to be caused by a complication of ____________.
  • 3. 
    Trophoblast are cells of the embryo that become ________, are cells that become ______, and are cells biopsied during CVS.
  • 4. 
    Abnormalities during fertilization may be caused by: 1) sperm fertilizes an _______ egg or       2) _____(#) sperm fertilize _____(#) egg. 
  • 5. 
    Check all that cause a "complete" molar pregnancy:
    • A. 

      Placenta grows and produces hCG

    • B. 

      Some fetal compnents

    • C. 

      Sperm fertilizes empty egg

    • D. 

      Two sperm fertilize one egg

    • E. 

      No fetus is formed

  • 6. 
    This is a range of benign and malignant diseases arising from excessive proliferation of trophoblastic tissue. 
  • 7. 
    When two sperm fertilize one egg, this creates an abnormal fetus and an abnormal _________.
  • 8. 
    Two sperm fertilize one egg --> check all that apply:
    • A. 

      No fetus

    • B. 

      Some fetal components

    • C. 

      "partial" mole

    • D. 

      Placenta grows and produces hCG

    • E. 

      Creates triploid fetus

    • F. 

      Abnormal fetus and placenta

  • 9. 
    Check all that apply to the clinical findings of Trophoblastic Disease AKA Molar Pregnancies:
    • A. 

      Hyperemesis gravidarum

    • B. 

      Rapid enlargement of uterus

    • C. 

      Grossly elevated hCG levels

    • D. 

      Uterine bleeding in 1st trimester

    • E. 

      Theca lutein cysts

    • F. 

      Early onset of pre-eclampsia

    • G. 

      Expulsion of vesicles

  • 10. 
    Hydatidiform mole, is a form of gestational trophoblastic disease, which may be ________ or ________.
  • 11. 
    This is the most common form of gestational trophoblastic disease.  It is characterized by trophoblastic hyperplasia, villous edema, abnormal villous vasculature, or absence of embryo. This is the result of fertilization of an empty oocyte by a single sperm with duplication of paternal material.  What is this referred to as?
  • 12. 
    An invasive mole is also known as ______________ destruens. 
  • 13. 
    An invasive mole is invasive, __________, non-metastatic form of gestational trophoblastic disease.
  • 14. 
    Chorioadenoma destruens is the penetration of the hydatidiform mole into the ____________.  it may penetrate the uterine wall and lead to life-threatening __________ and may require a hysterectomy.
  • 15. 
    This type of mole is the result of one set of maternal chromosomes and two sets of paternal chromosomes.
  • 16. 
    A partial mole is characterized by the presence of a ____ or fetal parts, referred to as a _________ fetus, and villous edema.
  • 17. 
    A partial mole may be visualized sonographically as an enlarged placenta containing cystic spaces or you may see a small fetus with defects or fetal parts.
    • A. 

      True

    • B. 

      False

  • 18. 
    This is the result of a twin pregnancy with normal development of one fetus and placenta & molar degeneration of the other ovum.  
  • 19. 
    Risk factor of trophoblastic disease:
    • A. 

      Over 40

    • B. 

      Low economic status

    • C. 

      Previous molar pregnancy

    • D. 

      Women living in far eastern countries

    • E. 

      Diets deficient in protein and folic acid

    • F. 

      30 or younger

  • 20. 
    This is the malignant, metastatic form of gestational trophoblastic disease; occurs 1:40,000 pregnancies:
  • 21. 
    The metastatic sites for choriocarcinoma are :
  • 22. 
    Check all that apply to the treatment of molar pregnancies:
    • A. 

      Frequent follow ups

    • B. 

      Evacuation of molar pregnancy

    • C. 

      Radiation

    • D. 

      Possible chemotherapy

    • E. 

      Serial hCG levels

  • 23. 
    Sonographic appearance of molar pregnancy in the 1st trimester:
    • A. 

      Bilateral theca lutein cyst

    • B. 

      Echogenic complex mass in uterine cavity

    • C. 

      Differential dx: blighted ovum

    • D. 

      Identification may be difficult within 1st trimester

  • 24. 
    In the 2nd trimester, molar pregnancy has a " ___________" appearance.
  • 25. 
    In the 2nd trimester, molar pregnancy is visualized as a _________ mass filling the uterine cavity, studded with small ________ spaces representing hydropic chorionic villi; bilateral _____ ______ cysts are visualized, as well as an ______ of a fetus or fetal parts.
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