Toxicology Of The Kidney
This quiz should test your knowledge on nephrotoxicity and help you further understand the toxicology in this vital organ
- 1.In Hyperphosphataemia, which compound is found in high concentration in the kidney?
- A.
Phosphate
- B.
Phosphatase
- C.
Calcium
- D.
Carbon
- 2.Acute Renal Failure (ARF) primarily occurs as a result of .....
- A.
Leakage of urea in the kidney
- B.
Inflammation of the kidney
- C.
Insufficient blood supply to the kidney
- 3.Hyperkalaemia is a build up of potassium ions. Which organ does this have the most detrimental effect on?
- A.
Lungs
- B.
Heart
- C.
Stomach
- 4.What do the NSAID's act to inhibit?
- A.
Gastric Acid Secretion
- B.
Urination
- C.
Cyclooxygenase (COX) Enzymes
- D.
Perspiration
- 5.Paracetamol possesses which of the following therapeutic effects?
- A.
Anti-Pyretic and Anti-Inflammatory
- B.
Anti-Inflammatory and Analgesic
- C.
Analgesic and Anti-Pyretic
- D.
Analgesic and Anti-Coagulant
- 6.Which of the following is NOT a symptom of nephrotoxicity caused by the NSAID's?
- A.
Papillary Necrosis
- B.
Acute Renal Insufficiency
- C.
Interstitial Nephritis
- D.
Swollen Abdomen
- 7.Aminoglycosides inhibit protein synthesis by irreversibily binding to
- A.
50S
- B.
30S
- C.
16S
- 8.What aminoglycoside was the first to be synthesised and the most commonly used?
- A.
Vancomycin
- B.
Neomycin
- C.
Gentamicin
- D.
Streptomycin
- 9.A common affect of aminoglycoside antibiotics is
- A.
Time dependent bacterial action
- B.
Postantibiotic effect
- C.
More active in acidic pH
- D.
Good oral absorption
- 10.What is the mechanism of action of ACE inhibitors?
- A.
Inhibit vasoconstriction
- B.
Promote conversion of angiotensin I into angiotensin II
- C.
Cause the production of angiotensin-converting enzyme
- D.
Inhibition of angiotensin-converting enzyme
- 11.ACE inhibitors would NOT be an effective treatment for which of these disorders?
- A.
Hypertension
- B.
After myocardial infarction
- C.
Hypotension
- D.
Heart failure
- 12.Patients suffering from which of these diseases are at risk of renal failure due to ACE inhibitors?
- A.
Schizophrenia
- B.
Heart failure
- C.
Parkinson's
- D.
Renal artery stenosis
- 13.Which of the following is not present in glomerular filtrate?
- A.
Salt
- B.
Vitamins
- C.
Amino acids
- D.
Albumin
- 14.The filtrate passes through the nephron in which correct order?
- A.
Loop of henle, distal convoluted tubule, glomerulus, proximal convuluted tubule, collecting duct.
- B.
Glomerulus, proximal convoluted tubule, loop of henle, distal convoluted tubule, collecting duct.
- C.
Collecting duct, loop of henle, proximal convoluted tubule, distal convoluted tubule, glomerulus.
- D.
Glomerulus, distal convoluted tubule, loop of henle, proximal convoluted tubule, collecting duct.
- 15.The medulla is involved with which functions of the kidney?
- A.
Filtration and secretion
- B.
Reabsorption and filtration
- C.
Reabsorption and secretion
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