A Trivia Quiz On The Diseases Of The Thyroid Gland
The thyroid gland is located in our neck and secretes various hormones responsible for regulating the metabolic rates and assisting in protein synthesis in mammals. The following quiz is designed to test your knowledge on the various diseases that affect the thyroid gland. Good Luck!
Questions and Answers
- 1.
Despite the availability of a wide array of thyroid hormone products, it is clear that ___________ is the treatment of choice for almost all patients with hypothyroidism.
- A.
Liothyronine (Cytomel)
- B.
Liotrix (Thryolar)
- C.
Synthetic levothyroxine (LT4)
- D.
Desiccared Thyroid (Armour, etc)
- E.
None of the above
Correct Answer
C. Synthetic levothyroxine (LT4)Explanation
Synthetic levothyroxine (LT4) is the treatment of choice for almost all patients with hypothyroidism because it is a synthetic form of the hormone thyroxine (T4) which is produced by the thyroid gland. LT4 is the most commonly prescribed thyroid hormone replacement therapy and has a consistent potency and stability, making it easier to regulate and adjust the dosage for individual patients. It also has a longer half-life compared to other thyroid hormone products, allowing for once-daily dosing and better patient compliance. Therefore, LT4 is considered the most effective and reliable treatment option for hypothyroidism.Rate this question:
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- 2.
Iodine deficiency can result in ________.
Correct Answer
goiters
a goiter
goiter
GOITERSExplanation
Iodine deficiency can result in the formation of goiters. A goiter is an enlarged thyroid gland, which can occur when the body does not have enough iodine to produce sufficient amounts of thyroid hormones. The term "goiters" is the plural form of goiter, indicating that multiple goiters can develop due to iodine deficiency.Rate this question:
- 3.
The thyroid gland is the largest endocrine gland in the body, residing in the neck, anterior to the trachea. It produces two biologically active hormones, T4 and T3. Most of the physiologic activity of thyroid hormones is from the actions of ____.
- A.
T4
- B.
T3
Correct Answer
B. T3Explanation
T4 can be thought of as a "prohormone"Rate this question:
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- 4.
80% of thyroid hormone is synthesized as T4 and stored in the thyroid bound to thyroglobulin. Thyroid hormones are released from the gland when needed, primarily under the influence of _____ from the anterior pituitary.
- A.
TSH (thyrotropin)
- B.
Thryoid binding globulin (TBG)
- C.
Transthyretin
Correct Answer
A. TSH (thyrotropin)Explanation
Thyroid hormones are synthesized as T4 and stored in the thyroid gland bound to thyroglobulin. When the body needs thyroid hormones, they are released from the gland. This release is primarily regulated by TSH (thyrotropin) from the anterior pituitary. TSH stimulates the thyroid gland to produce and release more thyroid hormones into the bloodstream. Therefore, TSH plays a crucial role in regulating thyroid hormone levels in the body.Rate this question:
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- 5.
TSH promotes the production and release of thyroid hormones from the gland. As circulating thyroid hormone levels rise to needed levels, positive feedback results in the decreased release of TSH.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
NEGATIVE FEEDBACK!!Rate this question:
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- 6.
High TSH but low FT4 suggests... Hint: TSH and FT4 levels going in opposite directions is usually what we expect to see, generally indicating a problem on the level of the thyroid.
- A.
Primary hyperthyroidism
- B.
Primary hypothyroidism
- C.
Pituitary hyperthyroidism
- D.
Pituitary hypothyroidism
- E.
Hypothalamus hypothyroidism
Correct Answer
B. Primary hypothyroidismExplanation
High TSH but low FT4 suggests primary hypothyroidism. In primary hypothyroidism, the thyroid gland is not producing enough thyroid hormones. This leads to an increase in TSH production from the pituitary gland as it tries to stimulate the thyroid to produce more hormones. However, since the thyroid is not functioning properly, the levels of FT4, which is a measure of active thyroid hormone, remain low. This imbalance between TSH and FT4 levels indicates a problem with the thyroid gland itself, rather than the pituitary or hypothalamus.Rate this question:
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- 7.
High TSH and high FT4 indicates __________ while low TSH and low FT4 indicate ___________.
- A.
Pituitary hyperthyroidism, Pituitary hypothalamic
- B.
Primary hyperthyroidism, Primary hypothyroidism
Correct Answer
A. Pituitary hyperthyroidism, Pituitary hypothalamicExplanation
High TSH and high FT4 levels indicate pituitary hyperthyroidism, which is a condition where the pituitary gland produces excessive amounts of thyroid-stimulating hormone (TSH). This excess TSH stimulates the thyroid gland to produce excessive amounts of thyroxine (FT4), leading to hyperthyroidism. On the other hand, low TSH and low FT4 levels indicate pituitary hypothalamic dysfunction, where the pituitary gland and hypothalamus fail to produce enough TSH and stimulate the thyroid gland adequately, resulting in primary hypothyroidism.Rate this question:
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- 8.
A radioactive iodine uptake test helps determine intrinsic thyroid function. A thyroid scan can help distinguish etiology (such as cancer). A TRH stimulation test helps determine thyroid and ________ function.
- A.
Liver
- B.
Pituitary
- C.
Intestinal
- D.
None of the above
Correct Answer
B. PituitaryExplanation
A TRH stimulation test helps determine thyroid and pituitary function. The pituitary gland produces and releases thyroid-stimulating hormone (TSH), which stimulates the thyroid gland to produce thyroid hormones. Therefore, by measuring the response of the thyroid gland to TRH (thyrotropin-releasing hormone), the test can assess the function of both the thyroid gland and the pituitary gland.Rate this question:
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- 9.
If a patient has just started a new dose of levothyroxine. When would you recommend she get her TFTs checked again?
- A.
6 hours
- B.
6 days
- C.
6 weeks
- D.
6 months
- E.
I wouldn't recommend anything because I'd be too busy calling Medco.
Correct Answer
C. 6 weeksExplanation
The correct answer is 6 weeks. Levothyroxine is a medication used to treat hypothyroidism. It takes time for the medication to reach its full effect and stabilize the thyroid hormone levels. Therefore, it is recommended to check the thyroid function tests (TFTs) after 6 weeks to assess the effectiveness of the medication and make any necessary adjustments to the dosage. Checking TFTs too soon may not provide an accurate reflection of the medication's effect, while waiting too long may delay necessary adjustments.Rate this question:
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- 10.
The target goal for TSH levels...
- A.
0.5 to 5
- B.
0.3 to 3
Correct Answer
B. 0.3 to 3Explanation
The target goal for TSH levels is 0.3 to 3. This range is considered normal and indicates that the thyroid gland is functioning properly. TSH (thyroid-stimulating hormone) is produced by the pituitary gland and regulates the production of thyroid hormones. TSH levels outside of this range may indicate an underactive or overactive thyroid gland, which can lead to various health issues. Therefore, maintaining TSH levels within the range of 0.3 to 3 is important for optimal thyroid function.Rate this question:
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- 11.
Grave's disease (a type of hyperthyroidism) is prominent in...
- A.
Females
- B.
Males
- C.
Children
Correct Answer
A. FemalesExplanation
Grave's disease, a type of hyperthyroidism, is prominent in females. This is because the condition is believed to be an autoimmune disorder, and women are more prone to autoimmune diseases compared to men. Additionally, hormonal factors may also play a role in the higher prevalence of Grave's disease in females.Rate this question:
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- 12.
Some causes of hypothyroidism include iatrogenic causes, drugs (such as amiodarone and lithium), and this (also known as autoimmune thyroiditis)....
- A.
Grave's
- B.
Hashimoto's
- C.
Silent thyroiditis
- D.
Hypothalamic disease
- E.
Pituitary disease
Correct Answer
B. Hashimoto'sExplanation
Hashimoto's disease, also known as autoimmune thyroiditis, is a common cause of hypothyroidism. It is an autoimmune disorder where the immune system mistakenly attacks the thyroid gland, leading to inflammation and damage. This results in a decreased production of thyroid hormones, causing hypothyroidism. Other causes mentioned in the question, such as Grave's disease, silent thyroiditis, hypothalamic disease, and pituitary disease, are not associated with hypothyroidism.Rate this question:
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- 13.
What drug is best for a pregnant patient with hyperthyroidism?
- A.
PTU
- B.
Methimazole
- C.
No drugs. She should have a thyroidectomy.
- D.
No drugs during pregnancy. She should wait until after delivering her child to start treatment.
Correct Answer
A. PTUExplanation
PTU (propylthiouracil) is the best drug for a pregnant patient with hyperthyroidism. Both PTU and methimazole are antithyroid drugs used to treat hyperthyroidism, but PTU is considered safer during pregnancy. Methimazole may pose a risk of birth defects, particularly in the first trimester, while PTU has a lower risk. However, in certain cases where PTU is not well-tolerated or ineffective, methimazole may be used after careful consideration of the risks and benefits. Surgery, such as thyroidectomy, is generally not recommended during pregnancy unless there are severe complications or uncontrolled hyperthyroidism. Waiting until after delivery to start treatment is also not recommended as untreated hyperthyroidism can have adverse effects on both the mother and the baby.Rate this question:
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- 14.
What is the most feared side effect of antithyroid drug therapy?
Correct Answer
agranulocytosis
AGRANULOCYTOSIS
AgranulocytosisExplanation
Agranulocytosis is the most feared side effect of antithyroid drug therapy. Agranulocytosis is a condition characterized by a severe decrease in the number of white blood cells, specifically granulocytes. This condition can lead to a weakened immune system, making the body more susceptible to infections. It is a potentially life-threatening side effect that requires immediate medical attention. Monitoring of blood cell counts is crucial during antithyroid drug therapy to detect agranulocytosis early and prevent complications.Rate this question:
- 15.
Which antithyroid drug has a longer half-life (5 hours)?
- A.
PTU
- B.
Methimazole
Correct Answer
B. MethimazoleExplanation
Methimazole has a longer half-life of 5 hours compared to PTU. This means that it takes approximately 5 hours for half of the drug to be eliminated from the body. A longer half-life suggests that the drug remains in the body for a longer duration, allowing for less frequent dosing compared to PTU.Rate this question:
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- 16.
What is a common adverse event that happens after a patient undergoes radioactive therapy?
- A.
Nausea and pruritis
- B.
Hypothyroidism, mild thinning of hair, dysphagia
- C.
Hyperthyroidism, thickening of hair, weight loss
- D.
Weight gain, pruritis, cough
- E.
Cough, nausea, dysphagia
Correct Answer
B. Hypothyroidism, mild thinning of hair, dysphagiaExplanation
After undergoing radioactive therapy, a common adverse event that can occur is hypothyroidism, which is a condition where the thyroid gland does not produce enough thyroid hormone. This can lead to symptoms such as fatigue, weight gain, and thinning of hair. Dysphagia, which is difficulty swallowing, can also occur as a result of the therapy. These symptoms are commonly associated with the effects of radioactive therapy on the thyroid gland.Rate this question:
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- 17.
Agranulocytosis often presents as a sore throat.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Agranulocytosis is a condition characterized by a severe decrease in the number of granulocytes, a type of white blood cell. These cells play a crucial role in the body's immune response. When the number of granulocytes is significantly reduced, it weakens the immune system's ability to fight off infections. One common symptom of agranulocytosis is a sore throat, as the lack of granulocytes makes the throat more susceptible to infections. Therefore, it is true that agranulocytosis often presents as a sore throat.Rate this question:
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- 18.
Large doses of iodide inhibit the synthesis and release of thyroid hormones. Iodides are used most commonly in Graves' disease patients prior to surgery and to quickly reduce hormone release in patients with thyroid storm. Potassium iodide is administered as a saturated solution named this...
Correct Answer
sski
SSKI
SskiExplanation
Potassium iodide is administered as a saturated solution named SSKI. This solution is used to inhibit the synthesis and release of thyroid hormones in patients with Graves' disease before surgery or in patients experiencing a thyroid storm. The correct answer is sski, SSKI, or Sski.Rate this question:
- 19.
Nervousness, weakness, increased perspiration, weight loss, and tachycardia are signs of...
- A.
Hypothyroidism
- B.
Hyperthyroidism
Correct Answer
B. HyperthyroidismExplanation
Nervousness, weakness, increased perspiration, weight loss, and tachycardia are all symptoms commonly associated with hyperthyroidism. In this condition, the thyroid gland produces an excessive amount of thyroid hormones, leading to an overactive metabolism. This can result in weight loss, increased heart rate (tachycardia), and other symptoms such as nervousness and weakness. Hypothyroidism, on the other hand, is characterized by an underactive thyroid gland and typically presents with different symptoms such as fatigue, weight gain, and depression.Rate this question:
-
(1).jpg "Despite the availability of a wide array of thyroid hormone products, it is clear that ___________ is the treatment of choice for almost all patients with hypothyroidism.")
(1).jpg "Iodine deficiency can result in ________.")
(1).jpg "The thyroid gland is the largest endocrine gland in the body, residing in the neck, anterior to the trachea. It produces two biologically active hormones, T4 and T3. Most of the physiologic activity of thyroid hormones is from the actions of ____.")
(1).jpg "80% of thyroid hormone is synthesized as T4 and stored in the thyroid bound to thyroglobulin. Thyroid hormones are released from the gland when needed, primarily under the influence of _____ from the anterior pituitary.")
(1).jpg "TSH promotes the production and release of thyroid hormones from the gland. As circulating thyroid hormone levels rise to needed levels, positive feedback results in the decreased release of TSH.")
(1).jpg "High TSH but low FT4 suggests...
Hint: TSH and FT4 levels going in opposite directions is usually what we expect to see, generally indicating a problem on the level of the thyroid.")
(1).jpg "High TSH and high FT4 indicates __________ while low TSH and low FT4 indicate ___________.")
(1).jpg "A radioactive iodine uptake test helps determine intrinsic thyroid function. A thyroid scan can help distinguish etiology (such as cancer). A TRH stimulation test helps determine thyroid and ________ function.")
.jpg "If a patient has just started a new dose of levothyroxine. When would you recommend she get her TFTs checked again?")
(1).jpg "The target goal for TSH levels...")
(2).jpg "Grave's disease (a type of hyperthyroidism) is prominent in...")
(1).jpg "Some causes of hypothyroidism include iatrogenic causes, drugs (such as amiodarone and lithium), and this (also known as autoimmune thyroiditis)....")
(1).jpg "What drug is best for a pregnant patient with hyperthyroidism?")
(1).jpg "What is the most feared side effect of antithyroid drug therapy?")
(1).jpg "Which antithyroid drug has a longer half-life (5 hours)?")
(1).jpg "What is a common adverse event that happens after a patient undergoes radioactive therapy?")
(1).jpg "Agranulocytosis often presents as a sore throat.")
(1).jpg "Large doses of iodide inhibit the synthesis and release of thyroid hormones. Iodides are used most commonly in Graves' disease patients prior to surgery and to quickly reduce hormone release in patients with thyroid storm. Potassium iodide is administered as a saturated solution named this...")
(1).jpg "Nervousness, weakness, increased perspiration, weight loss, and tachycardia are signs of...")
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Mar 21, 2023Quiz Edited by
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May 06, 2010Quiz Created by
Caitlinb
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