Teratogenesis Quiz

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Teratogenesis Quiz - Quiz

What do you know about Teratology? Have you ever read about Teratogenesis? Here we have a few teratogenesis MCQ quiz to test your knowledge regarding the different characteristics of teratogens during pregnancy. Teratogenesis is parental toxicity that causes malformations or birth abnormalities (such as intellectual disabilities) in an embryo or fetus. What else do you know about it? Let's check it out with the help of the quiz given below. So, what are you waiting for? Play the quiz now.


Questions and Answers
  • 1. 

    __________________ are Anatomical or Structural abnormalities present at birth.

    • A.

      Congenital Malformations

    • B.

      Inferential Malformations

    • C.

      Both A and B

    • D.

      None of the above

    Correct Answer
    A. Congenital Malformations
    Explanation
    Congenital malformations refer to anatomical or structural abnormalities that are present at birth. These abnormalities can occur due to genetic factors, environmental factors, or a combination of both. They can affect various body parts or systems, leading to physical or functional impairments. The term "congenital" indicates that these malformations are present from the time of birth and are not acquired later in life. Therefore, the correct answer is "Congenital Malformations."

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  • 2. 

    Approx 20% of __________ _________ are due to presence of Congenital Malformations.

    • A.

      Perinatal Deaths

    • B.

      Perinatal Births

    • C.

      Accidents

    • D.

      All of the above

    Correct Answer
    A. Perinatal Deaths
    Explanation
    Approximately 20% of perinatal deaths are due to the presence of Congenital Malformations. Perinatal deaths refer to the deaths of infants that occur during the perinatal period, which includes the late stages of pregnancy (usually starting at 22 weeks gestation) up to the first week after birth. Congenital malformations are structural abnormalities present at birth, which can range from minor to severe and can affect various body systems. This suggests that a significant proportion of perinatal deaths are attributed to these congenital malformations.

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  • 3. 

    A ________ is any substance causing abnormal structures in an embryo.

    • A.

      Teratogen

    • B.

      Estrogen

    • C.

      Progestrone

    • D.

      All of the above

    Correct Answer
    A. Teratogen
    Explanation
    A teratogen is any substance that can cause abnormal structures or development in an embryo. This means that exposure to teratogens during pregnancy can lead to birth defects or other abnormalities in the developing fetus. Estrogen and progesterone are hormones naturally produced by the body and do not typically cause abnormal structures in an embryo. Therefore, the correct answer is Teratogen.

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  • 4. 

    A term that is derived from the Greek Word __________ which means "Monster"

    • A.

      Oogenesis

    • B.

      Terato

    • C.

      Estrogen

    • D.

      Embryo

    Correct Answer
    B. Terato
    Explanation
    The term "terato" is derived from the Greek word meaning "monster".

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  • 5. 

    What are the Categories that Teratogens are divided into?

    • A.

      Drugs / Chemical Agents

    • B.

      Cold

    • C.

      Radiation

    • D.

      Heat

    • E.

      Animals

    Correct Answer(s)
    A. Drugs / Chemical Agents
    C. Radiation
    D. Heat
    Explanation
    Teratogens are substances or factors that can cause birth defects or developmental abnormalities in a fetus. They are categorized into drugs/chemical agents, radiation, and heat. Drugs and chemical agents can include medications, illegal drugs, alcohol, and certain environmental toxins. Radiation refers to exposure to ionizing radiation, such as X-rays or radioactive materials. Heat can be harmful to a developing fetus, especially in excessive amounts. These categories help to identify and understand the different types of teratogens and their potential risks to a developing baby.

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  • 6. 

    With Radiation studies on Post Hiroshima babies showed an increase in the rate of?

    • A.

      Microcephaly (Small Head)

    • B.

      Facial Clefting

    • C.

      Skeletal Malformations

    • D.

      IUGR

    • E.

      Mental Retardation

    Correct Answer(s)
    A. Microcephaly (Small Head)
    C. Skeletal Malformations
    E. Mental Retardation
  • 7. 

    The Teratogen HEAT is defined as?

    • A.

      Hypothermia

    • B.

      Hyperthermia

    • C.

      Both A and B

    • D.

      None of the above

    Correct Answer
    B. Hyperthermia
    Explanation
    Hyperthermia is the correct answer because the term "teratogen" refers to any substance or factor that can cause malformations or abnormalities in a developing fetus. Hyperthermia specifically refers to an elevated body temperature, which can be harmful to the developing fetus and increase the risk of birth defects. Hypothermia, on the other hand, refers to a low body temperature and is not typically associated with teratogenic effects. Therefore, the correct answer is hyperthermia as it aligns with the definition of a teratogen.

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  • 8. 

    __________ will cause Fatal Cataracts ONLY if the fetus is infected while the lens is undergoing development.

    • A.

      Rubella

    • B.

      Rubeola 

    • C.

      Chickenpox

    • D.

      All of the above

    Correct Answer
    A. Rubella
    Explanation
    Rubella can cause fatal cataracts only if the fetus is infected while the lens is undergoing development. Rubella is a viral infection that can be passed from a pregnant woman to her unborn baby. If the virus infects the baby during the critical period of lens development, it can lead to the formation of cataracts, which can be fatal. Cataracts are a clouding of the lens in the eye, and if they develop during fetal development, they can cause severe visual impairment or even blindness. Rubeola (measles) and chickenpox do not specifically cause fatal cataracts in the same way that rubella does.

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  • 9. 

    Name the 5 Congenital Malformations that are of increased risk with HEAT

    • A.

      IUGR

    • B.

      Mental Retardation

    • C.

      Microcephaly (Small Head)

    • D.

      Skeletal Malformation

    • E.

      Facial Clefting

    • F.

      Micrognathia (Small Jaw)

    • G.

      Neural Tube Defects

    Correct Answer(s)
    A. IUGR
    C. Microcephaly (Small Head)
    E. Facial Clefting
    F. Micrognathia (Small Jaw)
    G. Neural Tube Defects
    Explanation
    The correct answer includes five congenital malformations that are of increased risk with HEAT: IUGR (intrauterine growth restriction), Microcephaly (small head), Facial Clefting, Micrognathia (small jaw), and Neural Tube Defects. These malformations are associated with increased risk when a pregnant woman is exposed to high levels of heat, which can lead to developmental abnormalities in the fetus.

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  • 10. 

    Category X Drugs are........

    • A.

      Drugs that have been tested to be Safe in Pregnancy

    • B.

      Drugs that do not cause major Birth Defects

    • C.

      Drugs that have been shown to cause birth defects and should never be taken during pregnancy

    • D.

      All of the above

    Correct Answer
    C. Drugs that have been shown to cause birth defects and should never be taken during pregnancy
    Explanation
    Category X drugs are drugs that have been shown to cause birth defects and should never be taken during pregnancy. This category indicates that there is evidence of fetal risk based on human or animal studies, and the potential benefits of using the drug during pregnancy outweigh the potential risks. Therefore, these drugs should be avoided during pregnancy to minimize the risk of harm to the developing fetus.

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  • 11. 

    What category drugs have a clear health risk for the Fetus.

    • A.

      Category D

    • B.

      Category C

    • C.

      Category B

    • D.

      Category A

    Correct Answer
    A. Category D
    Explanation
    Category D drugs have a clear health risk for the fetus. These drugs have been shown to cause harm to the fetus in studies or have a high potential for causing harm based on animal studies. The risks of using these drugs during pregnancy may outweigh the potential benefits, and they should only be used if there are no safer alternatives available. It is important for pregnant women to consult with their healthcare provider before taking any medications to ensure the safety of both the mother and the fetus.

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  • 12. 

    Category A include drugs such as ..........

    • A.

      Antibiotics, Acetaminophen (Tylenol), Aspartame, Pepcid, Cortisone, Insulin (for Diabetes), and Ibuprofen (Advil, Motrin) Before 3rd trimester

    • B.

      Thyroid medicine in moderation, or in prescribed doses, Folic Acid, and Vitamin B6

    • C.

      Some Antidepressants, Compazine, Sudafed, Diflucan, Cipro

    • D.

      Chemotherapy drugs to treat cancer Alcohol, Lithium (used to treat Manic Depression), Dilantin

    • E.

      DES (Diethylstilbestrol), Sedative, Accutane, Tegison or Soriatane (Used to treat Psoriasis)

    Correct Answer
    B. Thyroid medicine in moderation, or in prescribed doses, Folic Acid, and Vitamin B6
    Explanation
    The correct answer includes drugs that are safe to use during pregnancy. Thyroid medicine in moderation or in prescribed doses is safe because maintaining proper thyroid function is important for the health of both the mother and the baby. Folic acid is essential for the development of the baby's neural tube and can help prevent birth defects. Vitamin B6 is commonly used to treat morning sickness and is considered safe during pregnancy. These drugs have been deemed safe and beneficial for pregnant women based on scientific research and medical guidelines.

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  • 13. 

    Category B include drugs such as........

    • A.

      Antibiotics, Acetaminophen (Tylenol), Aspartame, Pepcid, Cortisone, Insulin (for Diabetes), and Ibuprofen (Advil, Motrin) Before 3rd trimester

    • B.

      Thyroid medicine in moderation, or in prescribed doses, Folic Acid, and Vitamin B6

    • C.

      Some Antidepressants, Compazine, Sudafed, Diflucan, Cipro

    • D.

      Chemotherapy drugs to treat cancer Alcohol, Lithium (used to treat Manic Depression), Dilantin

    • E.

      DES (Diethylstilbestrol), Sedative, Accutane, Tegison or Soriatane (Used to treat Psoriasis)

    Correct Answer
    A. Antibiotics, Acetaminophen (Tylenol), Aspartame, Pepcid, Cortisone, Insulin (for Diabetes), and Ibuprofen (Advil, Motrin) Before 3rd trimester
    Explanation
    The drugs listed in the answer are considered safe to use during pregnancy before the third trimester. Antibiotics are commonly prescribed to treat infections, while Acetaminophen (Tylenol) is a commonly used pain reliever. Aspartame is an artificial sweetener, and Pepcid is used to treat heartburn. Cortisone is a steroid medication used to reduce inflammation, and Insulin is used to manage diabetes. Ibuprofen (Advil, Motrin) is a nonsteroidal anti-inflammatory drug. It is important to note that this information is specific to the time period before the third trimester, and the safety of these drugs may vary during other stages of pregnancy.

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  • 14. 

    Category C include drugs such as.........

    • A.

      Antibiotics, Acetaminophen (Tylenol), Aspartame, Pepcid, Cortisone, Insulin (for Diabetes), and Ibuprofen (Advil, Motrin) Before 3rd trimester

    • B.

      Thyroid medicine in moderation, or in prescribed doses, Folic Acid, and Vitamin B6

    • C.

      Some Antidepressants, Compazine, Sudafed, Diflucan, Cipro

    • D.

      Chemotherapy drugs to treat cancer Alcohol, Lithium (used to treat Manic Depression), Dilantin

    • E.

      DES (Diethylstilbestrol), Sedative, Accutane, Tegison or Soriatane (Used to treat Psoriasis)

    Correct Answer
    C. Some Antidepressants, Compazine, Sudafed, Diflucan, Cipro
    Explanation
    The drugs listed in the answer are all known to have potential risks and side effects during pregnancy. Some antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), have been associated with an increased risk of certain birth defects. Compazine, Sudafed, Diflucan, and Cipro are all medications that should be used with caution during pregnancy due to potential risks to the developing fetus. It is important for pregnant women to consult with their healthcare provider before taking any medication to ensure the safety of both the mother and the baby.

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  • 15. 

    Category D include drugs such as........

    • A.

      Antibiotics, Acetaminophen (Tylenol), Aspartame, Pepcid, Cortisone, Insulin (for Diabetes), and Ibuprofen (Advil, Motrin) Before 3rd trimester

    • B.

      Thyroid medicine in moderation, or in prescribed doses, Folic Acid, and Vitamin B6

    • C.

      Some Antidepressants, Compazine, Sudafed, Diflucan, Cipro

    • D.

      Chemotherapy drugs to treat cancer Alcohol, Lithium (used to treat Manic Depression), Dilantin

    • E.

      DES (Diethylstilbestrol), Sedative, Accutane, Tegison or Soriatane (Used to treat Psoriasis)

    Correct Answer
    D. Chemotherapy drugs to treat cancer Alcohol, Lithium (used to treat Manic Depression), Dilantin
    Explanation
    Chemotherapy drugs are used to treat cancer and can have harmful effects on a developing fetus. Alcohol consumption during pregnancy can lead to fetal alcohol spectrum disorders and other birth defects. Lithium, a medication used to treat manic depression, has been associated with an increased risk of birth defects. Dilantin, an anticonvulsant medication, has also been linked to birth defects when taken during pregnancy. Therefore, these drugs should be avoided during pregnancy to ensure the health and safety of the baby.

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  • 16. 

    Category X include drugs such as........

    • A.

      Antibiotics, Acetaminophen (Tylenol), Aspartame, Pepcid, Cortisone, Insulin (for Diabetes), and Ibuprofen (Advil, Motrin) Before 3rd trimester

    • B.

      Thyroid medicine in moderation, or in prescribed doses, Folic Acid, and Vitamin B6

    • C.

      Some Antidepressants, Compazine, Sudafed, Diflucan, Cipro

    • D.

      Chemotherapy drugs to treat cancer Alcohol, Lithium (used to treat Manic Depression), Dilantin

    • E.

      DES (Diethylstilbestrol), Sedative, Accutane, Tegison or Soriatane (Used to treat Psoriasis)

    Correct Answer
    E. DES (Diethylstilbestrol), Sedative, Accutane, Tegison or Soriatane (Used to treat Psoriasis)
    Explanation
    The drugs listed in the answer are known to be harmful or potentially harmful during pregnancy. DES (Diethylstilbestrol) is a synthetic estrogen that was prescribed to pregnant women in the past but has been found to cause reproductive issues in their children. Sedatives can affect the development of the baby's central nervous system. Accutane, Tegison, and Soriatane are all medications used to treat psoriasis and have been linked to birth defects. Therefore, these drugs should be avoided during pregnancy to ensure the health and safety of the baby.

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  • 17. 

    Children born to women who were prescribed DES are prone to.....

    • A.

      High Miscarriage Rate

    • B.

      Reproductive Cancers (Cervical, Vaginal)

    • C.

      Infertility

    • D.

      All of the above

    Correct Answer
    D. All of the above
    Explanation
    Children born to women who were prescribed DES (diethylstilbestrol) are prone to a high miscarriage rate, reproductive cancers (cervical, vaginal), and infertility. DES is a synthetic estrogen that was prescribed to pregnant women between the 1940s and 1970s to prevent miscarriages. However, it was later discovered that DES exposure in the womb can lead to a variety of health issues in the children, including an increased risk of miscarriage, reproductive cancers, and fertility problems. Therefore, the correct answer is "All of the above."

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  • 18. 

    What drug was used as an a Anti-emetic, withdrawn in 1961

    • A.

      Thalidomide

    • B.

      Pregabalin 

    • C.

      Methylcobalamin

    • D.

      All of the above

    Correct Answer
    A. Thalidomide
    Explanation
    Thalidomide was used as an anti-emetic medication but was withdrawn in 1961 due to its severe teratogenic effects, causing birth defects in infants. It was initially prescribed to pregnant women to alleviate morning sickness but resulted in thousands of babies being born with limb abnormalities and other deformities. The tragic consequences of thalidomide led to stricter regulations on drug testing and approval processes to ensure the safety of medications, especially during pregnancy.

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  • 19. 

    What drug was prescribed to women in 1960-1975 to reduce the risk of miscarriage?

    • A.

      Diethylstilbestrol

    • B.

      Stilbestrol

    • C.

      Stilboestrol

    • D.

      All of the above

    Correct Answer
    D. All of the above
    Explanation
    During the period of 1960-1975, the drug Diethylstilbestrol (also known as stilbestrol or stilboestrol) was prescribed to women to reduce the risk of miscarriage. Therefore, the correct answer is "All of the above" as all three options refer to the same drug.

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  • 20. 

    Children born to women who were prescribed Thalidomide are known to have.....

    • A.

      Congenital Heart Malformations

    • B.

      Reproductive Cancers (Cervical, Vaginal)

    • C.

      Spine Malformations

    • D.

      Limb Reduction

    • E.

      Duodenal Stenosis or Atresia

    • F.

      Pyloric Stenosis

    • G.

      Microtia

    Correct Answer(s)
    A. Congenital Heart Malformations
    C. Spine Malformations
    D. Limb Reduction
    E. Duodenal Stenosis or Atresia
    F. Pyloric Stenosis
    G. Microtia
    Explanation
    Children born to women who were prescribed Thalidomide are known to have a range of birth defects including congenital heart malformations, spine malformations, limb reduction, duodenal stenosis or atresia, pyloric stenosis, and microtia. Thalidomide was a medication prescribed to pregnant women in the 1950s and 1960s to treat morning sickness, but it was later discovered to cause severe birth defects. These defects can vary in severity and can have lifelong implications for the affected individuals.

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  • 21. 

    The Teratogen Category Drugs / Chemical Agents include ......

    • A.

      Alcohol

    • B.

      Thyroid Drugs

    • C.

      Daunorubicin

    • D.

      Methyl Mercury

    • E.

      All of the above

    Correct Answer
    E. All of the above
    Explanation
    The correct answer is "All of the above". This is because all the options listed - Alcohol, Thyroid Drugs, Daunorubicin, and Methyl Mercury - fall under the category of Teratogens. Teratogens are substances that can cause birth defects or developmental abnormalities in a fetus when exposed to them during pregnancy.

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  • 22. 

    With the Teratogen HEAT Exposure between ____ to ____ weeks increases the risk for Congenital Malformations

    • A.

      4,14

    • B.

      5,15

    • C.

      3,15

    • D.

      None of the above

    Correct Answer
    A. 4,14
    Explanation
    Exposure to teratogen HEAT between 4 to 14 weeks of pregnancy increases the risk for congenital malformations. This suggests that during this specific time period, the developing fetus is particularly vulnerable to the harmful effects of heat exposure, which can result in the formation of structural abnormalities or birth defects. It is important for pregnant women to be cautious and avoid excessive heat exposure during this critical period to minimize the risk of congenital malformations.

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