Tc 1: February, Cefi /Anafortan

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| By Suman
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Suman
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Quizzes Created: 15 | Total Attempts: 8,089
Questions: 20 | Attempts: 859

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Tc 1: February, Cefi /Anafortan - Quiz

Hi ! Welcome to the February E-Test on Cefi & Anafortan. Please fill up all required data before attempting the quiz. Only the first attempt will be considered for scoring. Repeated attempts with different user ID's may result in blocking, which please note.


Questions and Answers
  • 1. 

    With anti spasmodic drugs ,side effects such as dizziness, dryness of mouth are caused by

    • A.

      Inhibition of the cholinesterase enzyme

    • B.

      Blocking the muscarinic receptors

    • C.

      Inhibiting PDE4

    • D.

      Inhibiting calcium channels

    Correct Answer
    B. Blocking the muscarinic receptors
    Explanation
    Blocking the muscarinic receptors can lead to side effects such as dizziness and dryness of mouth. Muscarinic receptors are found in various tissues including the salivary glands and the inner ear. By blocking these receptors, the normal functioning of these tissues is disrupted, leading to the side effects mentioned.

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  • 2. 

    While comparing pain score reduction of Anafortan with Dicyclomine, "VAS" stands for 

    • A.

      Visual Analysis Scale

    • B.

      Visual Analogue Scale

    • C.

      Visual Analogue Score

    • D.

      Visual Activity Score

    Correct Answer
    B. Visual Analogue Scale
    Explanation
    The correct answer is Visual Analogue Scale. The Visual Analogue Scale is a measurement tool used to assess pain intensity or other subjective experiences. It typically consists of a horizontal line with anchor points representing extremes of the experience being measured, such as "no pain" and "worst pain imaginable." Participants are asked to mark their level of pain along the line, and the distance from the anchor point provides a numerical rating of pain intensity. In this context, the VAS is used to compare the reduction in pain scores between Anafortan and Dicyclomine.

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  • 3. 

    Dicyclomine acts only by anticholinergic action

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    Dicyclomine does not act solely by anticholinergic action. While it does have anticholinergic properties, it also exhibits direct smooth muscle relaxant effects. Therefore, the statement that dicyclomine acts only by anticholinergic action is false.

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  • 4. 

    Each 2 ml ampoule of Anaspas Injection contains

    • A.

      Camylofin 25 mg + Diclofenac Sodium 25 mg

    • B.

      Camylofin 50 mg + Diclofenac Sodium 50 mg

    • C.

      Camylofin 50 mg + Diclofenac Potassium 50 mg

    • D.

      Camylofin 25 mg + Diclofenac Potassium 25 mg

    Correct Answer
    B. Camylofin 50 mg + Diclofenac Sodium 50 mg
    Explanation
    The correct answer is Camylofin 50 mg + Diclofenac Sodium 50 mg. This is because the question asks for the contents of each 2 ml ampoule of Anaspas Injection, and the correct answer provides the combination of Camylofin and Diclofenac Sodium in the correct dosage of 50 mg each. The other options either have different dosages or include Diclofenac Potassium instead of Diclofenac Sodium.

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  • 5. 

    In smooth muscle cells, "Cytosolic Calcium" levels are reduced due to

    • A.

      Anti Cholinergic Action

    • B.

      Peripheral Action

    • C.

      Both the options

    • D.

      None of the options

    Correct Answer
    B. Peripheral Action
    Explanation
    Smooth muscle cells are regulated by the level of cytosolic calcium, which plays a crucial role in muscle contraction. In this case, the correct answer is "Peripheral Action." This means that the reduction in cytosolic calcium levels is due to actions occurring outside of the cell. Peripheral actions can include factors such as the release of neurotransmitters or hormones, which can inhibit calcium influx into the cell or enhance calcium efflux. By reducing cytosolic calcium levels, peripheral actions ultimately lead to relaxation of smooth muscle cells.

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  • 6. 

    With Camylofin the "Peripheral Action" is by,

    • A.

      Produces PDE4 enzyme, restores Camp levels & thus reduces Ca ⁺⁺ ion levels in the smooth muscle cell.

    • B.

      Inhibits PDE4 enzyme, increases Camp levels & thus reduces Ca ⁺⁺ ion levels in the smooth muscle cell.

    • C.

      Inhibits PDE4 enzyme, restores Camp levels & thus increases Ca ⁺⁺ ion levels in the smooth muscle cell.

    • D.

      Inhibits PDE4 enzyme, restores Camp levels & thus reduces Ca ⁺⁺ ion levels in the smooth muscle cell.

    Correct Answer
    D. Inhibits PDE4 enzyme, restores Camp levels & thus reduces Ca ⁺⁺ ion levels in the smooth muscle cell.
    Explanation
    The correct answer is "Inhibits PDE4 enzyme, restores Camp levels & thus reduces Ca ⁺⁺ ion levels in the smooth muscle cell." This means that Camylofin inhibits the PDE4 enzyme, which leads to an increase in Camp levels. This increase in Camp levels then results in a reduction of Ca ⁺⁺ ion levels in the smooth muscle cell.

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  • 7. 

    The neuro transmitter responsible for smooth muscle contraction & dilation is

    • A.

      Histamine

    • B.

      Acetyl Choline

    • C.

      Leukotrine

    • D.

      Serotonin

    Correct Answer
    B. Acetyl Choline
    Explanation
    Acetylcholine is the correct answer because it is a neurotransmitter that is responsible for smooth muscle contraction and dilation. It is released by nerve cells to transmit signals to muscle cells, causing them to contract. Acetylcholine is involved in various bodily functions, including the contraction of smooth muscles in the gastrointestinal tract, blood vessels, and respiratory system. It also plays a role in the dilation of blood vessels. Therefore, acetylcholine is the neurotransmitter responsible for smooth muscle contraction and dilation.

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  • 8. 

    What is the composition of Hyocimax Plus tablet ?

    • A.

      Hyoscine butylbromide 10 mg + Paracetamol 500 mg

    • B.

      Hyoscine butylbromide 20 mg + Paracetamol 500 mg

    • C.

      Hyoscine butylbromide 10 mg + Paracetamol 325 mg

    • D.

      Hyoscine butylbromide 25 mg + Paracetamol 300 mg

    Correct Answer
    A. Hyoscine butylbromide 10 mg + Paracetamol 500 mg
    Explanation
    The correct answer is Hyoscine butylbromide 10 mg + Paracetamol 500 mg. This is because the composition of the Hyocimax Plus tablet includes 10 mg of Hyoscine butylbromide and 500 mg of Paracetamol.

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  • 9. 

    What is "Cytosolic Calcium"?

    • A.

      Calcium levels outside the cell

    • B.

      Calcium levels outside the mitochondria

    • C.

      Calcium levels inside the mitochondria

    • D.

      Calcium levels inside the cell

    Correct Answer
    D. Calcium levels inside the cell
    Explanation
    Cytosolic calcium refers to the levels of calcium inside the cell. Calcium plays a crucial role in various cellular processes, including muscle contraction, signal transduction, and enzyme activation. Maintaining the appropriate concentration of calcium within the cell is essential for proper cell function.

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  • 10. 

    Cefixime belongs to which group of drugs ?

    • A.

      Beta Lactum group of antibiotics

    • B.

      Penicillin group

    • C.

      Macrolides

    • D.

      Aminoglycosides

    Correct Answer
    A. Beta Lactum group of antibiotics
    Explanation
    Cefixime belongs to the Beta Lactum group of antibiotics. This group of antibiotics includes drugs that have a beta-lactam ring in their chemical structure. Cefixime is a third-generation cephalosporin antibiotic, which is a subclass of beta-lactam antibiotics. These antibiotics work by inhibiting the synthesis of the bacterial cell wall, leading to the death of the bacteria.

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  • 11. 

    III rd generation Cephalosporins are predominantly active against

    • A.

      Gram -ve pathogens & very less on Gram +ve pathogens

    • B.

      Gram +ve pathogens & very less on Gram -ve pathogens

    • C.

      Gram -ve pathogens & also Gram +ve pathogens

    • D.

      Gram -ve pathogens, Gram +ve pathogens & Atypical pathogens

    Correct Answer
    C. Gram -ve pathogens & also Gram +ve pathogens
    Explanation
    IIIrd generation Cephalosporins are effective against both Gram-negative and Gram-positive pathogens. This means that they can target and kill bacteria belonging to both these categories.

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  • 12. 

    With Cefi,Patient Hygiene Awareness is a campaign on

    • A.

      Upgrading skills & knowledge

    • B.

      Documented clinical evidence

    • C.

      Prevention of infections

    • D.

      Facts on infection trends

    Correct Answer
    C. Prevention of infections
    Explanation
    The correct answer is "Prevention of infections." This is because the given campaign, "With Cefi, Patient Hygiene Awareness," is focused on preventing infections. The other options, such as upgrading skills and knowledge, documented clinical evidence, and facts on infection trends, may be important aspects of the campaign, but the main goal is to prevent infections.

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  • 13. 

    For Surgeons the indication for Cefi is

    • A.

      Typhoid fever

    • B.

      Uncomplicated UTI

    • C.

      RTI

    • D.

      All of the options

    Correct Answer
    B. Uncomplicated UTI
    Explanation
    The correct answer is "Uncomplicated UTI." Cefi is indicated for the treatment of uncomplicated urinary tract infections (UTIs). UTIs are caused by bacteria and can affect the bladder, urethra, or kidneys. Cefi is an antibiotic that is effective against the bacteria commonly associated with UTIs. It works by inhibiting the growth and multiplication of these bacteria, helping to eliminate the infection. Cefi is not indicated for the treatment of typhoid fever or respiratory tract infections (RTIs). Therefore, the correct answer is uncomplicated UTI.

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  • 14. 

    In sinusitis the clinical cure rates with Cefi is

    • A.

      > 95 %

    • B.

      94%

    • C.

      95.9%

    • D.

      None of the options

    Correct Answer
    B. 94%
    Explanation
    The correct answer is 94%. This means that when Cefi is used to treat sinusitis, the clinical cure rate is 94%. This indicates that a majority of patients who were treated with Cefi experienced a cure of their sinusitis symptoms. It is important to note that this answer is based on the information provided and may not be applicable in all cases or situations.

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  • 15. 

    The mode of action of IIIrd generation Cephalosporins is

    • A.

      Inhibits Cell wall synthesis

    • B.

      Inhibits DNA Gyrase & Topoisomerase IV

    • C.

      Inhibits 50 S subunit of Ribosome

    • D.

      Inhibits 30 S subunit of Ribosome

    Correct Answer
    A. Inhibits Cell wall synthesis
    Explanation
    The correct answer is "Inhibits Cell wall synthesis." Third-generation cephalosporins, like other cephalosporins, work by inhibiting the synthesis of the bacterial cell wall. They do this by binding to and inhibiting the enzymes called penicillin-binding proteins (PBPs), which are responsible for the cross-linking of peptidoglycan chains in the cell wall. By inhibiting cell wall synthesis, these antibiotics weaken the bacterial cell wall, leading to cell lysis and death.

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  • 16. 

    In children the dose of Cefixime in typhoid is

    • A.

      8mg/kg/day in single/two divided doses

    • B.

      20mg/kg in two divided doses

    • C.

      15 mg/kg/day in single/two divided doses

    • D.

      25mg/kg in two divided doses

    Correct Answer
    B. 20mg/kg in two divided doses
    Explanation
    The correct answer is 20mg/kg in two divided doses. This is the recommended dose of Cefixime in children for the treatment of typhoid. The dosage is based on the child's weight, with a dose of 20mg per kilogram of body weight. The dose is divided into two equal doses given at different times throughout the day. This dosage regimen ensures that the medication is effective in treating the infection and helps to minimize the risk of side effects.

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  • 17. 

    Beta Lactamase is released by

    • A.

      Beta Lactum antibiotic

    • B.

      Bacteria

    • C.

      Beta Lactamase Inhibitor

    • D.

      None of the options

    Correct Answer
    B. Bacteria
    Explanation
    Beta lactamase is an enzyme that is released by bacteria. This enzyme is capable of breaking down beta lactam antibiotics, which are a class of antibiotics that include penicillins and cephalosporins. Bacteria produce beta lactamase as a defense mechanism to protect themselves from the effects of these antibiotics. When beta lactamase is released, it inactivates the antibiotics by breaking down their beta lactam ring structure, rendering them ineffective against the bacteria. Therefore, the correct answer is bacteria.

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  • 18. 

    86.7 % cure rates with Cefi is achieved in

    • A.

      URTI

    • B.

      UTI

    • C.

      AOM

    • D.

      RTI

    Correct Answer
    C. AOM
    Explanation
    Cefi has been found to be highly effective in treating Acute Otitis Media (AOM), which is an infection of the middle ear. The high cure rate of 86.7% suggests that Cefi is successful in treating this particular condition. However, it may not be as effective in treating other respiratory infections such as Upper Respiratory Tract Infection (URTI) or Respiratory Tract Infection (RTI). Therefore, the answer is AOM.

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  • 19. 

    Active phase of labor is termed when the cervix is dilated by

    • A.

      5 cm

    • B.

      4 mm

    • C.

      3 cm

    • D.

      3 mm

    Correct Answer
    C. 3 cm
    Explanation
    The active phase of labor is defined as the period when the cervix is dilated by at least 3 cm. This is an important milestone as it indicates that labor is progressing and the baby is descending further into the birth canal. The cervix needs to reach a certain level of dilation for the baby to be able to pass through during delivery. Once the cervix is dilated by 3 cm, contractions become stronger and more regular, helping to further open the cervix and facilitate the birth process.

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  • 20. 

    A Musculotropic drug  is 

    • A.

      A drug which controls spasm

    • B.

      A drug that reduces colic

    • C.

      A drug acting on a muscle tissue

    • D.

      All of the options

    Correct Answer
    C. A drug acting on a muscle tissue
    Explanation
    The correct answer is "A drug acting on a muscle tissue." A musculotropic drug refers to a drug that specifically targets and acts on muscle tissue. It can be used to relax or contract muscles, depending on the desired effect. This type of drug is commonly used in the treatment of muscle spasms, muscle pain, and other conditions affecting muscle function.

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Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Mar 20, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Feb 15, 2015
    Quiz Created by
    Suman
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