Pharmacotherapy - Diabetes Cont...

20 Questions | Total Attempts: 83

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Diabetes Quizzes & Trivia

Questions and Answers
  • 1. 
    To decrease the probability of the somogyi effect....
    • A. 

      Inject NPH at dinner and not HS

    • B. 

      Inject NPH HS and not at dinner

  • 2. 
    Rotating sites prevents...
    • A. 

      Lipoatrophy

    • B. 

      Lipohypertrophy

    • C. 

      Somogyi effect

    • D. 

      Dawn phenomenon

  • 3. 
    Type 2 diabetics usually need more exogenous insulin.
    • A. 

      True

    • B. 

      False

  • 4. 
    Basal insulin should equal __________ of your total daily dose
    • A. 

      1/3 - 2/3

    • B. 

      1/2 - 2/3

    • C. 

      1/3 - 3/4

    • D. 

      1/4 - 1/2

  • 5. 
    Generally patients will be 1 unit of rapid acting insulin per ___ grams of carbohydrates.
    • A. 

      5

    • B. 

      15

    • C. 

      25

    • D. 

      35

  • 6. 
    If your blood glucose levels are out of target at midafternoon, you should check...
    • A. 

      Pre-supper and rapid acting insulin

    • B. 

      Evening NPH and long-acting insulin

    • C. 

      Morning NPH and long-acting insulin

    • D. 

      Pre-lunch rapid/short-acting insulin and morning NPH

    • E. 

      Pre-breakfast rapid-acting insulin

  • 7. 
    If your blood glucose levels are out of target postlunch/presupper, you should check...
    • A. 

      Pre-lunch rapid/short insulin and/or morning NPH

    • B. 

      Pre-breakfast rapid/short acting

    • C. 

      Pre-supper rapid/short insulin

    • D. 

      Morning NPH, or long-acting insulin

  • 8. 
    If your blood glucose levels are out of target in the early morning, you should check...
    • A. 

      Pre-supper rapid/short insulin

    • B. 

      Evening NPH, or long-acting insulin

    • C. 

      Evening NPH, or long-acting insulin

    • D. 

      Pre-breakfast rapid/short acting

  • 9. 
    Can you shake insulin?
    • A. 

      Yes

    • B. 

      No

  • 10. 
    Injecting in the ____________ is the preferred site for insulin injection because of less variability and faster absorption.
    • A. 

      Butt

    • B. 

      Thigh

    • C. 

      Arm

    • D. 

      Abdomen

  • 11. 
    Which of the following statements regarding metformin are true?  Select all that apply.
    • A. 

      It decreases hepatic glucose production

    • B. 

      It increases peripheral glucose uptake and utilization

    • C. 

      It can cause hypoglycemia as monotherapy

    • D. 

      It generally causes patients to gain a few pounds

    • E. 

      SCr should less than than 1.5 for a male and 1.4 for a female in order to use

    • F. 

      It should be avoided in patients with heart failure

    • G. 

      It can decrease vitamin B12 levels

    • H. 

      The optimal dose is 2550mg/day

    • I. 

      One third of patients have GI complaints

    • J. 

      Metformin XR can be a ghost tablet

  • 12. 
    Which of the following are associated with less GI upset with metformin?  Select all that apply.
    • A. 

      Dividing dosing with meals and gradually increasing the dose

    • B. 

      Not exceeding 2000mg/day

    • C. 

      Switching to Metformin XR

  • 13. 
    Which of the following are true regarding sulfonylureas?  Select all that apply.
    • A. 

      They increase beta cell insulin secretion

    • B. 

      They cause hypoglycemia

    • C. 

      They cause weight loss

    • D. 

      Chlorpropramide can cause SIADH and disulfiramin like reaction

    • E. 

      They can be toxic to beta cells if BG is over 300 mg/dL

    • F. 

      They probably work better in patients that have had diabetes less than 5 years

    • G. 

      They can accumulate in renal impairment

    • H. 

      50% of patients continue to respond adequately to a sulfonyulrea after 10 years

  • 14. 
    Which sulfonylurea is better to use if a patient has renal impairment?
    • A. 

      Chlorpropramide

    • B. 

      Glipizide

    • C. 

      Glyburide

    • D. 

      Glimepiride

  • 15. 
    Which of the following statements are true regarding meglitinides?  Select all that apply.
    • A. 

      They have a very rapid onset and should be taken immediately before a meal

    • B. 

      They are glucose dependent

    • C. 

      If you skip a meal it is okay to still take the medication

    • D. 

      They possibly have less hypoglycemia than sulfonylureas

  • 16. 
    Which of the following are true regarding alpha glucosidase inhibitors?
    • A. 

      They blunt the effects of carbohydrates in the gut

    • B. 

      They cause flatulence and bloating

    • C. 

      They do not cause hypoglycemia as monotherapy

    • D. 

      Glucose and lactose should be used to treat hypoglycemia

  • 17. 
    Which of the following statements regarding TZDs are correct?  Select all that apply.
    • A. 

      Their initial response occurs within the first week and the peak response occurs in a 2 to 4 weeks after initiation

    • B. 

      They do not cause hypoglycemia as monotherapy

    • C. 

      They are agonists of PPAR gamma

    • D. 

      They can increase ovulation in women with PCOS

    • E. 

      They may increase one's risk of fractures

    • F. 

      They are contraindicated in patients with Class III and Class IV heart failure

    • G. 

      Actos can help improve cholesterol

    • H. 

      They usually cause GI upset

    • I. 

      They may cause an increase in LFTs

  • 18. 
    Which drugs would be the safest to use in renal dysfunction?
    • A. 

      Metformin and a glinide

    • B. 

      A glinide and Actos

    • C. 

      Sulfonyulreas and Metformin

    • D. 

      Actos and Januvia

    • E. 

      Januvia and a sulfonylurea

  • 19. 
    What is the main contraindication for the DPP-IV inhibitors?
    • A. 

      Renal impairment

    • B. 

      Hepatic impairment

    • C. 

      Lactic acidosis

    • D. 

      Radiographic contrast administration

    • E. 

      There are no CIs with DPP-IV inhibitors

  • 20. 
    A patient comes in that is on metformin.  She just underwent a procedure that used radiographic contrast dye and her doctor told her to stop taking her metformin.  She is wondering if she can restart her metformin.  You tell her...
    • A. 

      Do not take metformin ever again

    • B. 

      It is safe to take metformin after the procedure, just not before the procedure

    • C. 

      Wait 48 hours after the completion of the procedure to start taking metformin again

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