Pharmacology Quiz: The Endocrine System!
This is a pharmacology quiz about the Endocrine System! The endocrine system is charged with making hormones that control moods, organs, and growth. The endocrine glands are divided into the thyroid gland and the adrenal glands. There are a lot of issues that can arise in the system and prevent it from functioning correctly. There are also different prescribed drugs, and this quiz will test how well you know them and their effect.
- 1.Which condition results from over secretion of growth hormone?
- A.
Panhypopituitarism
- B.
Addison's
- C.
Acromegaly
- D.
Diabetes
- 2.Which drug may be prescribed to treat hypothyroidism?
- A.
Pegvisomant
- B.
Insulin
- C.
Desmopressin
- D.
Levothyroxine
- 3.This G protein-coupled receptor acts to decrease cAMP concentration intracellularly.
- A.
Gs protein coupled receptor
- B.
Gi protein coupled receptor
- C.
Gq protein coupled receptor
- D.
Gh protein coupled receptor
- 4.Activation of this G protein-coupled receptor results in the second messengers IP3 and DAG.
- A.
Gq coupled receptor
- B.
Gi coupled receptor
- C.
Gb coupled receptor
- D.
Gs coupled receptor
- 5.Lack of ADH causes diabetes insipidus. This drug may be prescribed to combat the disorder.
- A.
Insulin
- B.
Metformin
- C.
Desomopressin
- D.
Octreotide
- 6.This drug combats acromegaly by acting as somatostatin, a growth hormone release inhibiting factor.
- A.
Octreotide
- B.
Pegvisomant
- C.
Sodium iodide 131
- D.
Desmopressin
- 7.Which of the following hormones are released from the anterior pituitary?
- A.
Prolactin
- B.
ADH
- C.
TSH
- D.
Oxytocin
- 8.This drug acts as a synthetic T4 hormone.
- A.
Levothyroxine
- B.
Pegvisomant
- C.
Metformin
- D.
PTU
- 9.This drug treats hyperthyroidism by inhibiting T3 and T4 production in the thyroid gland, and by preventing T3 conversion to T4 in tissues.
- A.
Mineralocorticoids
- B.
Propylthiouracil
- C.
Sodium iodide 131
- D.
Insulin
- 10.Lack of glucocorticoids with primary causes would be attributed to which condition?
- A.
Cushing's
- B.
Hashimoto's
- C.
Addison's
- D.
Hyperthyrodism
- 11.Which drug increases liver and tissue sensitivity to insulin by activating AMP-activated protein kinases which play a key role in insulin signaling?
- A.
Alpha glucosidase inhibitors
- B.
Orlistat
- C.
Metformin
- D.
Dopamine agonist
- 12.This drug inhibits/slows the digestion of sugars in the digestive tract.
- A.
Biguanides
- B.
Bile acid sequesterants
- C.
Alpha glucosidase inhibitor
- D.
Orlistat
- 13.Anti-obesity agents (orlistat) work by...
- A.
Inhibiting lipase
- B.
Stimulating lipase
- C.
Inhibiting glucagon
- D.
Stimulating glucagon
- 14.Insulin secretagogues include...
- A.
TZD
- B.
Sulfonylureas
- C.
Meglitinides
- D.
GLP-1
- 15.Sulfonylureas and meglitinides both work by inhibiting the outflux of potassium ions from the beta cells in the pancreas. This then causes depolarization of the cell, leading to the release of insulin. They differ from each other in the following way.
- A.
Sulfonylureas have less efficacy then meglitinides, leading to less incidences of hypoglycemia
- B.
Meglitinides bind to a different site then sulfonylureas, have a shorter duration of action, and have less risk of hypoglycemia
- C.
Meglitinides only cause partial depolarization of the cell, resulting in less insulin release
- 16.The sodium glucose co-transporter is a _________ and its function is to_____________.
- A.
Anti-hypertensive, reduce blood pressure through the kidneys
- B.
Anti-hypoglycemic, increase blood sugar through the liver
- C.
Anti-hypothyrodic, increase levels of T4 from thyroid gland
- D.
Anti-diabetic, decrease amount of glucose reabsorbed by kidney
- 17.Postmenopausal women should not take hormone replacement therapy if...
- A.
They have begun menopause less then five years ago
- B.
They have begun menopause more then five years ago
- C.
They have an absence of troublesome symptoms
- D.
They have a family Hx of estrogen sensitive breast cancer
- 18.Estriol is a type of estrogen that is predominately present during...
- A.
Fertile years
- B.
Menopause
- C.
Pregnancy
- 19.Oral contraceptives consisting of progesterone-only consist of a cycle of....
- A.
21 days on, 7 days off
- B.
84 days on, 7 days off
- C.
Continuous administration
- D.
30 days on, 7 days off
- 20.Depo-Provera is not recommended for use longer than 2 years. This is because...
- A.
It has been shown to decrease bone mass
- B.
It can cause breast cancer
- C.
It carries high risk of thromboembolism
- D.
It can cause endometrial cancers
- 21.This type of estrogen is primarily present in menopausal women.
- A.
Estradiol
- B.
Estrone
- C.
Estriol
- D.
Progesterone
- 22.Oral contraceptives can come with the following administration instructions.
- A.
84 days on, 7 days off
- B.
21 days on, 7 days off
- C.
30 days on, 7 days off
- D.
42 days on, 7 days off
- 23.If two doses of the progesterone-only pill are missed, the client should be advised to...
- A.
Use a barrier method for one week
- B.
Use a barrier method for 48 hours
- C.
Use a barrier method for 24 hours
- D.
Use a barrier method for the rest of the monthly cycle
- 24.The following are examples of post-coital contraception.
- A.
Mifepristone
- B.
High dose estrogen
- C.
Estrogen and progesterone combinations
- D.
Misoprostol
- 25.Mifepristone works by...
- A.
Causing uterine contractions
- B.
Thickening cervical mucus
- C.
Creating a hostile endometrium
- D.
Causing the slough off of the endometrium
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