Based on chapter 7 of Nancy Carolines emergency medicine on the streets. Chapter 7
Process by which a medication moves throughout the body
Study of medications and their effects or actions throughout the body.
Transfer of medications to specific organs in the human body
Study of the metabolism and action of medications in the body
Are considered safe enough that most people will not hurt themselves accidentally by taking the medicine as instructed
Have been available as prescription-only medications for at least 5 years and have undergone extensive clinical research.
Possess no more than half the strength of the prescription form and do not cause harm if they are taken in excessive amounts.
Have been approved by the FDA and have been shown to possess a physiologic effect equivalent to the prescription form.
Trade
Official
Chemical
Legal
Cordarone
Amiodarone usp
Amiodaron
2-butyl-3-benzofuranyl 4-{2-diethylamino}-ethoxoy-3,5-diiodophenyl ketone hydrochloride
It must be made available to the public in both its trade and generic forms
Its active ingredients must be within 95% to 105% of that stated on the label
It must be on the market in its generic form for a period of at least 36 months.
The manufacturer of the medication must prove that it does not cause any side effects
Follows national standards
Is done in an expedient manner
Will not result in side effects
Is safe, therapeutic, and effective
Brain and spinal cord
Somatic and autonomic nervous system
Central and peripheral nervous system
Sympathetic and parasympathetic nervous system
Autonomic nervous system
Somatic nervous system
Involuntary nervous system
Parasympathetic nervous system
Acetycholine
Acetylcholinesterase
Glycogen
Epinephrine and norepinephrine
Anticholineric
Sympathomimetic
Sympatholytic
Parasympatholytic
Antagonism
Neurotransmission
Chemotransmission
Nerve innervation
Excessive lacrimation, bradycardia, diarrhea, and miosis
Tachycardia, hypertension, dilated pupils, and nervousness
Dehydration, decreased urine production, and double vision
Muscle fasciculations, generalized weakness, and bradycardia
Synergistic
An agonist
An antagonist
A competitive binder
Patients gender
Type of medication
Route of administration
Weight of medication
Rectal, intramuscular
Intravenous,oral
Inhalation,topical
Rectal,subcutaneous
The patient may aspirate the medication
The medication may cause damage to the liver
The medication is metabolized too rapidly
Absorption is slow and unpredictable
Is identical to that of the IV route because the medication enters a noncollapsible channel with rapid flow into the central circulation
Is relatively unpredictable compared to that of the IV route because the intraosseous space is a low-pressure space
Is just as fast as that of the IV route, but only if the patient has adequate circulation and a systolic BP of at least 90 mm Hg
Is somewhat slower than that of the IV route because the medication must first pass through the microvasculature before entering the central circulation
Are hypertensive and tachycardic
Have decreased liver or renal function
Require less than 5 mL of medication
Have inadequate peripheral perfusion
Liver
Spleen
Kidneys
Small intestine
It make take hours before the medication is absorbed and exerts its effect
The process of biotransformation will be completely unpredictable
The dose should be doubled in order to achieve a therapeutic effect
It may not be excreted efficiently and may be accumulated to toxic levels
Addiction
Dependence
Tolerance
An idiosyncrasy
Diluted with sterile saline
Kept out of direct sunlight
Stored in a cold environment
Replaces every 30 to 60 days
Storage requirements
Mechanism of action
Side and adverse effects
Indications and proper dosage
Ibuprofen (motrin)
Naloxone (Narcan)
Acetylsalicylic acid (asa/aspirin)
Fentanyl (sublimaze)
Melatonin
Dopamine
Epinephrine
Norepinephrine
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