Osteoporosis Bone Disease Quiz

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| By Caitlinb
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Caitlinb
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Quizzes Created: 12 | Total Attempts: 9,301
Questions: 18 | Attempts: 2,362

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Osteoporosis Bone Disease Quiz - Quiz

The most common bone disease affected humans. . .


Questions and Answers
  • 1. 

    Which of the following are components of bone strength?

    • A.

      BMD and bone quality

    • B.

      BMD and bone strength

    • C.

      Bone type and bone quality

    • D.

      Bone strength and Vitamin D levels

    • E.

      BMD and calcium levels

    Correct Answer
    A. BMD and bone quality
    Explanation
    Bone strength is determined by two main factors: bone mineral density (BMD) and bone quality. BMD refers to the amount of minerals, such as calcium, present in the bone, which directly affects its strength. However, bone quality also plays a crucial role in determining bone strength. Bone quality refers to the structure and integrity of the bone, including factors such as bone architecture, microstructure, and collagen content. Both BMD and bone quality are important components of bone strength, making the answer "BMD and bone quality" correct.

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  • 2. 

    Patients with vertebral fractures may experience chronic pain, height loss, _____.  This can cause restrictive lung disease and involves curvature of the upper spine.

    Correct Answer
    KYPHOSIS
    Kyphosis
    kyphosis
    Explanation
    Patients with vertebral fractures may experience chronic pain, height loss, and kyphosis. Kyphosis is a condition characterized by an excessive forward curvature of the upper spine. This can lead to a hunched posture and restricted lung function, causing restrictive lung disease.

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  • 3. 

    Women have accelerated bone loss surrounding menopause owing to loss of estrogen. Yet, osteoporosis can also develop from secondary causes such as:(check all that apply)

    • A.

      Hypogonadism

    • B.

      Glucocorticoid use

    • C.

      Skeletal cancer

    • D.

      Alcoholism

    • E.

      Eating disorders

    Correct Answer(s)
    A. Hypogonadism
    B. Glucocorticoid use
    C. Skeletal cancer
    D. Alcoholism
    E. Eating disorders
    Explanation
    During menopause, women experience a decrease in estrogen levels, which can lead to accelerated bone loss. This is why osteoporosis is more common in women. However, osteoporosis can also develop from secondary causes such as hypogonadism, which is a condition where the body doesn't produce enough sex hormones; glucocorticoid use, which refers to the long-term use of corticosteroids that can weaken bones; skeletal cancer, which can cause bone destruction; alcoholism, which can interfere with bone formation and increase the risk of fractures; and eating disorders, which can lead to malnutrition and decreased bone density.

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  • 4. 

    The human skeleton consists of both corticol and trabecular bone.  Under normal circumstances, the skeleton undergoes a dynamic process of bone remodeling.  Osteoclasts are involved with resorption.  Resorption is also known as...

    • A.

      Bone buildup

    • B.

      Bone breakdown

    Correct Answer
    B. Bone breakdown
    Explanation
    Under normal circumstances, the human skeleton undergoes a dynamic process of bone remodeling. Osteoclasts, which are involved with resorption, play a key role in this process. Resorption refers to the breakdown of bone tissue.

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  • 5. 

    A standardized approach to measuring BMD for the diagnosis of osteoporosis include peripheral bone mineral density measurements.

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    Peripheral BMD measurements cannot be used for diagnosis because they do not correlate with central measurements (such as the hip). However, they are useful in identifying patients who are candidates for central DXA.

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  • 6. 

    A white 60 year old woman walks up to the pharmacy counter with a cup of Starbucks in her hand.  She states that her mom had osteoporosis and was wondering if she should be screened?

    • A.

      Yes

    • B.

      No

    Correct Answer
    A. Yes
    Explanation
    While her age is less than 65...she has risk factors. Her race, having a first degree relative, and coffee consumption increase her risk.

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  • 7. 

    All current national guidelines for BMD testing agree routine screening should occur for women aged ___ or older.

    • A.

      55

    • B.

      60

    • C.

      65

    • D.

      70

    Correct Answer
    C. 65
    Explanation
    All current national guidelines for BMD testing agree routine screening should occur for women aged 65 or older. This means that it is recommended for women who are 65 years old or above to undergo routine screening for BMD (bone mineral density). This screening helps to assess the strength and health of the bones, and can help in early detection and management of osteoporosis or other bone-related conditions. Regular screening is important for older women as they are at a higher risk of developing bone-related issues.

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  • 8. 

    A T-score is the number of standard deviations from the mean bone mineral density in healthy young white women.  Osteoporosis is defined as a T-score at least -2.5 standard deviations below the mean. Osteopenia is defined as a T-score between -2.5 and -1.0 standard deviations below the mean.

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    The statement is true because a T-score is a measure of how many standard deviations a person's bone mineral density is from the mean of healthy young white women. Osteoporosis is defined as a T-score of at least -2.5 standard deviations below the mean, while osteopenia is defined as a T-score between -2.5 and -1.0 standard deviations below the mean. Therefore, the statement accurately describes the definitions of osteoporosis and osteopenia based on T-scores.

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  • 9. 

    Which of the following are risk factors for osteoporosis?(check all that apply)

    • A.

      White/Asian

    • B.

      Having had a hysterectomy

    • C.

      Having a small body frame

    • D.

      Eating prednisone like candy for more than 3 months

    • E.

      Poor diet

    Correct Answer(s)
    A. White/Asian
    B. Having had a hysterectomy
    C. Having a small body frame
    D. Eating prednisone like candy for more than 3 months
    E. Poor diet
    Explanation
    Osteoporosis is a condition characterized by weak and brittle bones. The risk factors for osteoporosis include being White or Asian, having had a hysterectomy, having a small body frame, eating prednisone like candy for more than 3 months, and having a poor diet. Being White or Asian is a risk factor because individuals from these ethnic backgrounds tend to have lower bone density. Having had a hysterectomy can increase the risk of osteoporosis due to hormonal changes. A small body frame means less bone mass, which can make bones more susceptible to osteoporosis. Eating prednisone, a medication known to weaken bones, for an extended period can also increase the risk. Finally, a poor diet lacking in essential nutrients for bone health can contribute to osteoporosis.

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  • 10. 

    Which medications are associated with bone loss?(check all that apply)

    • A.

      Aromatase Inhibitors

    • B.

      IM Medroxyprogesterone

    • C.

      Immunosuppressive meds (such as cyclosporine)

    • D.

      Amoxicillin

    • E.

      Excessive levothyroxine doses

    Correct Answer(s)
    A. Aromatase Inhibitors
    B. IM Medroxyprogesterone
    C. Immunosuppressive meds (such as cyclosporine)
    E. Excessive levothyroxine doses
    Explanation
    Aromatase inhibitors, IM medroxyprogesterone, immunosuppressive medications (such as cyclosporine), and excessive levothyroxine doses are all associated with bone loss. Aromatase inhibitors are commonly used in the treatment of breast cancer and can cause bone loss by inhibiting estrogen production. IM medroxyprogesterone is a hormonal contraceptive that can also lead to bone loss. Immunosuppressive medications, like cyclosporine, are used to prevent rejection in organ transplant patients and can contribute to bone loss. Excessive doses of levothyroxine, a medication used to treat hypothyroidism, can also have negative effects on bone health.

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  • 11. 

    Kidney stones may occur with use of...

    • A.

      Calcium Oxalate

    • B.

      Calcium Carbonate

    Correct Answer
    A. Calcium Oxalate
    Explanation
    Kidney stones may occur with the use of calcium oxalate. Calcium oxalate is a common type of kidney stone that forms when there is too much oxalate and calcium in the urine. Oxalate is a naturally occurring substance found in many foods, and when it combines with calcium in the urine, it can form crystals that can eventually develop into kidney stones. Therefore, the presence of calcium oxalate in the urine can increase the risk of kidney stone formation.

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  • 12. 

    NOF guidelines for BMD treatment include a T-score below -1.0 by central DXA and FRAX risk probability greater than or equal to 20% or greater than or equal to  ____ for hip fracture.

    • A.

      1%

    • B.

      3%

    • C.

      5%

    • D.

      7%

    • E.

      10%

    Correct Answer
    B. 3%
    Explanation
    The NOF guidelines for BMD treatment include a T-score below -1.0 by central DXA and FRAX risk probability greater than or equal to 20% or greater than or equal to 3% for hip fracture. This means that if a patient has a T-score below -1.0 and a FRAX risk probability of 3% or higher for hip fracture, they would meet the criteria for BMD treatment according to the NOF guidelines.

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  • 13. 

    A patient presents to the pharmacy seeking information about treatment for her bone loss.  She is allergic to bisphosphonates.  She has chronic pain and is really hoping for a medication that inhibits osteoclast activity.  She also just recently bought a new refrigerator and would  like to use it as much as she can.  What would be the best drug for her?

    • A.

      Ibandronate

    • B.

      Raloxifene

    • C.

      Calcitonin

    • D.

      Teriparitide

    • E.

      Alendronate

    Correct Answer
    C. Calcitonin
    Explanation
    Some mild analgesic activity. Store in refrigerator when unopened, stable at room temp for 4 weeks.

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  • 14. 

    Zolendronate is given as an IV infusion 5mg over 15 minutes _______.  The most common adverse events include myalgia, headache, arthralgia, and pain in extremities.

    • A.

      Once a week

    • B.

      Once a month

    • C.

      Once every three months

    • D.

      Once every year

    • E.

      Once per lifetime

    Correct Answer
    D. Once every year
    Explanation
    Zolendronate is given as an IV infusion once every year. This dosing schedule is supported by the statement that the most common adverse events include myalgia, headache, arthralgia, and pain in extremities. These adverse events are typically associated with the use of Zolendronate and the once-yearly dosing helps to minimize their occurrence while still providing the desired therapeutic effects.

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  • 15. 

    SERMs not only help improve BMD but they are a good choice for post-menopausal women due to their hot-flash reducing effects.

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    SERMS can cause hot flashes and leg cramps.

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  • 16. 

    Which form of calcium contains the highest elemental calcium?

    • A.

      Calcium gluconate

    • B.

      Calcium Lactate

    • C.

      Calcium Citrate

    • D.

      Calcium Carbonate

    Correct Answer
    D. Calcium Carbonate
    Explanation
    Calcium Carbonate contains the highest elemental calcium among the given options. Calcium carbonate is a common form of calcium supplement, often used to treat calcium deficiency. It contains 40% elemental calcium, which means that for every 1000 mg of calcium carbonate, 400 mg is actual calcium. Calcium carbonate is also widely available and affordable, making it a popular choice for calcium supplementation.

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  • 17. 

    Concern exists over the use of chronic bisphosphonate therapy due to reports of  _____ osteonecrosis.Hint: your dentist might notice this before your doctor would

    Correct Answer
    jaw
    jawbone
    Jaw
    mandible
    Mandible
    Explanation
    Chronic bisphosphonate therapy has been associated with the development of osteonecrosis in the jaw. This condition, known as bisphosphonate-related osteonecrosis of the jaw (BRONJ), is characterized by the death of bone tissue in the jaw. Dentists are often the first to notice this condition as they may observe exposed bone, non-healing ulcers, or infections in the mouth. Therefore, it is important for patients on long-term bisphosphonate therapy to inform their dentists and undergo regular dental examinations to monitor for any signs of jaw osteonecrosis.

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  • 18. 

    Lab tests have little value in diagnosing osteoporosis but can be beneficial in identifying secondary causes of bone loss (such as hyperparathyroidism, hyperthyroidism, hypogonadism, cancer, or low vitamin D).

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    Lab tests are not very effective in diagnosing osteoporosis itself because they do not directly measure bone density. However, they can be helpful in identifying underlying conditions or factors that may contribute to bone loss, such as hyperparathyroidism, hyperthyroidism, hypogonadism, cancer, or low levels of vitamin D. These secondary causes of bone loss can be identified through lab tests, allowing for appropriate treatment and management. Therefore, lab tests have little value in diagnosing osteoporosis but can be beneficial in identifying secondary causes of bone loss.

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Quiz Review Timeline +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • May 29, 2024
    Quiz Edited by
    ProProfs Editorial Team
  • May 07, 2010
    Quiz Created by
    Caitlinb
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