Bcid Training - Module 3 Quiz

Think FDA-cleared targets

BioFire has 8 gram-positive bacterial targets on their BCID Panel.

The statement "All CoNs bacterial infections cause severe disease" is not true. CoNs (Coagulase-negative staphylococci) are a group of bacteria that are commonly found on the skin and mucous membranes of humans. While they can cause infections, not all CoNs infections are severe. In fact, many CoNs infections are mild and can be easily treated with antibiotics. Therefore, the correct answer is false.

CoNs stands for Coagulase-negative staphylococcus. Coagulase is an enzyme that helps in the formation of blood clots. Staphylococcus is a type of bacteria that can cause various infections in humans. Coagulase-negative staphylococcus refers to a group of staphylococcal bacteria that do not produce the coagulase enzyme. These bacteria are commonly found on the skin and mucous membranes of humans and are considered opportunistic pathogens, meaning they can cause infections in individuals with weakened immune systems or in certain medical conditions.

BioFire is a molecular diagnostic test that can identify multiple pathogens causing bloodstream infections. It is not cleared for use after blood culture without a gram stain result. Gram stain is a preliminary test that helps in identifying the type of bacteria present in the blood sample, which is crucial information for determining the appropriate treatment. Without a gram stain result, it would be risky to rely solely on the BioFire test for diagnosis and treatment decisions. Therefore, the statement is false.

Nanosphere has a higher number of gram-negative resistance genes compared to BioFire's panel. This suggests that Nanosphere's panel is more comprehensive and can provide a wider range of information regarding gram-negative resistance.

Enterococci is a type of bacteria that is known for its resistance to various antibiotics. Vancomycin is an antibiotic that is commonly used to treat infections caused by enterococci. Therefore, the correct answer is Vancomycin.

Acinetobacter bacteria are known for their high resistance to antibiotics, making the statement "Acinetobacter bacteria are extremely resistant to most all antibiotics" true. This resistance is due to various mechanisms such as the production of enzymes that can inactivate antibiotics or the alteration of antibiotic targets. This resilience makes Acinetobacter infections difficult to treat and poses a significant challenge in healthcare settings.

BioFire has performance issues with polymicrobial infections containing Enterococcus faecalis and Streptococcus pyogenes. This means that when BioFire is used to detect and identify multiple microorganisms in a sample, it may have difficulty accurately identifying these two specific bacteria. This could result in false negative or false positive results, leading to potential misdiagnosis and inappropriate treatment.

The statement is false because Listeria does not belong to the family Enterobacteriaceae. Listeria is a genus of bacteria that is not classified within the Enterobacteriaceae family.

Enterobacteriaceae species are highly associated with carbapenem resistance. Carbapenems are a class of antibiotics that are used as a last resort for treating serious infections caused by bacteria. However, Enterobacteriaceae species, such as Escherichia coli and Klebsiella pneumoniae, have developed resistance to carbapenems through the production of enzymes called carbapenemases. This resistance is a major concern in healthcare settings as it limits the treatment options for infections caused by these bacteria, leading to increased morbidity and mortality rates.

Gram-negative bacteria have an outer membrane that acts as a protective barrier, making it more difficult for antibiotics to penetrate and kill the bacteria. This outer membrane also contains efflux pumps that can actively pump out antibiotics, further contributing to their resistance. In contrast, gram-positive bacteria lack this outer membrane and are generally more susceptible to antibiotics. Therefore, the statement that gram-negative bacteria are more resistant to antibiotics than gram-positive species is true.

BioFire's BCID Panel has 2 gram-positive resistance genes.

The statement is false because Listeria monocytogenes is the species that commonly infects humans, not the entire Listeria genus. Therefore, a molecular BCID panel only needs to include Listeria monocytogenes to ensure adequate coverage.

Broad-spectrum antibiotics work on a wide range of bacteria, including both gram-positive and gram-negative bacteria. However, they do not have any effect on fungal infections. Therefore, the given statement is false.