Neurology/Psychiatry Exam #3 (ADHD/MS)

36 Questions | By Kmccor2008 | Last updated: Jun 19, 2019 | Total Attempts: 71

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1.

Fill in the blanks: According to the DSM-V (through future-magic) the diagnosis of ADHD in patient <17 years old requires ______ symptoms and the diagnosis of ADHD in patients >17 years old requires ______ symptoms.
- A.
  
  4 symptoms; 4 symptoms
- B.
  
  4 symptoms; 5 symptoms
- C.
  
  4 symptoms; 6 symptoms
- D.
  
  5 symptoms; 4 symptoms
- E.
  
  5 symptoms; 5 symptoms
- F.
  
  5 symptoms; 6 symptoms
- G.
  
  6 symptoms; 4 symptoms
- H.
  
  6 symptoms; 5 symptoms
- I.
  
  6 symptoms; 6 symptom
2.

Genetics plays a significant role in ADHD etiology.
- A.
  
  True
- B.
  
  False
3.

>70% of cases are genes associated with ADHD
- A.
  
  True
- B.
  
  False
4.

Which neurotransmitters are KNOWN to be involved in ADHD? (Select all that apply)
- A.
  
  Dopamine
- B.
  
  Norepinephrine
- C.
  
  Serotonin
- D.
  
  GABA
- E.
  
  Acetylcholine
5.

Methylphenidate (MPD) decreases dopamine and norepinephrine levels by inhibiting monoamine transporters. Specifically, decreasing dopamine causes improved signal-to-noise ratio improving attention span.
- A.
  
  True
- B.
  
  False
6.

Which medication blocks dopamine transporters, preventing uptake from the synaptic cleft?
- A.
  
  Amphetamine
- B.
  
  Methlyphenidate
- C.
  
  All of the above
7.

Which medication increases synaptic cleft levels of dopamine?
- A.
  
  Amphetamine
- B.
  
  Methylphenidate
- C.
  
  All of the above
8.

In addition to dopamine modification, what effect do Amphetamine and Methlyphenidate have on neuroanatomy of Norepinephrine neurons?
- A.
  
  Suppress locus coeruleus NE neurons
- B.
  
  Activate locus coeruleus NE neurons
- C.
  
  Suppress decimus meridius NE neurons
- D.
  
  Activate decimus meridius NE neurons
9.

Which qualities of bupropion (Wellbutrin) is FALSE?
- A.
  
  Selective Norepinephrine reuptake inhibitor
- B.
  
  Used mainly in adults
- C.
  
  Lacks potential for abuse
- D.
  
  Does have risk of seizures
10.

Which of the following is TRUE about Atomoxetine (Strattera)?
- A.
  
  Up to 3 weeks (5 half lives) to have full effect
- B.
  
  Moderate potential for abuse
- C.
  
  Only drug approved by the FDA for adult ADHD
- D.
  
  Requires multiple daily dosing at maintenance levels
11.

Alpha-2-Adrenoceptor agonists (clonidine and guanfacine) _____ NE release in the locum coeruleus
- A.
  
  Stimulate
- B.
  
  Inhibit
12.

Which Methylphenidate mediation has an osmotic release, which extends its effect up to 12 hours?
- A.
  
  Strattera
- B.
  
  Concerta
- C.
  
  Vyvanse
- D.
  
  Daytrana
13.

The transdermal methylphenidate patch is as effective as other formulations
- A.
  
  True
- B.
  
  False
14.

Focalin (or Dexmethlyphenidate) contains only the d-isomer of methylphenidate. As a result, the dose is 50% lower than methylphenidate and while efficacy is the same, tolerability of the medication is increased.
- A.
  
  True
- B.
  
  False
15.

Which of the follow would NOT be consider a common, specific adverse effect of stimulants?
- A.
  
  Anorexia
- B.
  
  Ataxia
- C.
  
  Headache
- D.
  
  Mood changes
16.

When would atomoxetine (Strattera) NOT be an alternative 1st line treatment?
- A.
  
  Anxiety disorder
- B.
  
  Intolerance to methylphenidate
- C.
  
  Metabolic disease
- D.
  
  Substance abuse disorder
17.

Which of the follow is not a precaution in use of atomoxetine (Strattera)?
- A.
  
  Blood dyscrasia
- B.
  
  Liver injury
- C.
  
  Urinary retention
- D.
  
  Suicidal ideation
18.

What is the starting/titration dose of atomoxetine (Straterra)?
- A.
  
  0.1 mg/kg/day
- B.
  
  0.5 mg/kg/day
- C.
  
  1 mg/kg/day
- D.
  
  5 mg/kg/day
19.

When treatment with Stimulants results in increased tics, treatment for ADHD with clonidine (catapres) can be considered.
- A.
  
  True
- B.
  
  False
20.

Within how long is typical onset of guanfacine treatment in ADHD experienced?
- A.
- B.
- C.
- D.
21.

Which of the following statements about ADHD in children is FALSE?
- A.
  
  90% respond to stimulant(s) alone
- B.
  
  Long-acting formulations are more preferred
- C.
  
  Lower doses for hyperactive type ADHD, higher doses for inattentive or combined form
- D.
  
  Medications are best studied in this age group
22.

In treatment of major depressive disorder in pediatric patients, combination cognitive behavior therapy and SSRI are better than either treatment alone
- A.
  
  True
- B.
  
  False
23.

Which of the following SSRI is NOT expert recommended in treatment of major depressive disorder in pediatric patients?
- A.
  
  Fluoxetine
- B.
  
  Citalopram
- C.
  
  Sertraline
- D.
  
  Paroxetine
24.

Which of the following is NOT a characteristic of Autism Spectrum Disorders?
- A.
  
  Delusions
- B.
  
  Impaired nonverbal/verbal communication
- C.
  
  Impaired social interactions
- D.
  
  Repetitive behaviors
25.

Which medication is FDA approved as a pharmacologic option for Autism Spectrum Disorders?
- A.
  
  Atomoxetine
- B.
  
  Clonidine
- C.
  
  Guanficine
- D.
  
  Risperidone