Para Neoplastic Neurological Syndrome Quiz Questions

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| By Ceolado
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Ceolado
Community Contributor
Quizzes Created: 4 | Total Attempts: 27,746
Questions: 5 | Attempts: 373

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Neurology Quizzes & Trivia

Questions and Answers
  • 1. 

    Antibodies implicated in Paraneoplastic Neurologic syndrome include the following except

    • A.

      Anti-Na

    • B.

      Anti-Yo

    • C.

      Anti-Hu

    • D.

      Anti-GAD

    Correct Answer
    A. Anti-Na
    Explanation
    All except Anti-Na are implicated. There are others too

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  • 2. 

    The least common cause of Paraneoplastic Neurologic Syndrome is

    • A.

      Leukamia

    • B.

      Neuroblastoma

    • C.

      Thymoma

    • D.

      Small Cell Lung Cancer

    Correct Answer
    A. Leukamia
    Explanation
    Other common cause is Sclerotic Myeloma

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  • 3. 

    Concerning ParaneolplasticNeurologic Syndrome is correct except

    • A.

      Limbic Menigitis is the commonest

    • B.

      Can occur in 30-50% of sclerotic myeloma/thymoma patients

    • C.

      It is caused Immune response triggered by neuronal protein produced by tumor

    • D.

      Limbic Encephalitis is an example

    Correct Answer
    A. Limbic Menigitis is the commonest
    Explanation
    Other examples of Paraneuroplastic Neurologic Syndrome are Subacute cerebellar ataxia, Opsoclonus-myoclonus and Sensory neuronopathy.

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  • 4. 

    The following concern Paraneoroplastic Neurologic Syndrome is incorrect

    • A.

      Neurologic antibodies are always present

    • B.

      Neurologic antibodies are not always present

    • C.

      A combination of Clinical, CSF and radiologic findings are necessary for diagnosis

    • D.

      Therapeutic intervention tumor growth can improve outcome

    Correct Answer
    A. Neurologic antibodies are always present
    Explanation
    Neurologic antibodies are not always present in up to 30% of cases.

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  • 5. 

    A 70 years patients who has been smoking for 40 years was observed to be losing weight, coughing and  having occasional seizures for 3 weeks. Three months to this presentation he was noted during a clinical visit to be depressed and having memory impairment. Which of the following is most likely to be diagnosis?

    • A.

      Small Cell Lung Cancer

    • B.

      Squamous Cell Cancer

    • C.

      Mesothelioma

    • D.

      Pulmonary Tuberculosis

    Correct Answer
    A. Small Cell Lung Cancer
    Explanation
    Long term smoking predispose to Lung Cancer especially Small cell cancer. Also it is very common cause of Paraneoplastic Neurologic Syndrome like Limbic encephalitis which can present as memory impairment, seizure and depression.

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