Laboratory Animal Technican Exam (Lat)

Reviewed by Editorial Team
The ProProfs editorial team is comprised of experienced subject matter experts. They've collectively created over 10,000 quizzes and lessons, serving over 100 million users. Our team includes in-house content moderators and subject matter experts, as well as a global network of rigorously trained contributors. All adhere to our comprehensive editorial guidelines, ensuring the delivery of high-quality content.
Learn about Our Editorial Process
| By ADastgir
A
ADastgir
Community Contributor
Quizzes Created: 1 | Total Attempts: 8,405
| Attempts: 8,405 | Questions: 155
Please wait...
Question 1 / 155
0 %
0/100
Score 0/100
1. Mice that have had DNA from a different animal inserted into thier genes are termed______

Explanation

Mice that have had DNA from a different animal inserted into their genes are termed "transgenic". This term is used to describe organisms that have had genetic material from another species introduced into their own genetic makeup. In the case of these mice, their DNA has been altered to include genes from a different animal, making them transgenic.

Submit
Please wait...
About This Quiz
Laboratory Animal Technican Exam (Lat) - Quiz

A exmaple of the possible test question taken from workbook manual, and other sources

Personalize your quiz and earn a certificate with your name on it!
2. What does GLP stand for?

Explanation

GLP stands for Good Laboratory Practices, which refers to a set of guidelines and regulations that ensure the quality and integrity of laboratory experiments and data. These practices include proper documentation, equipment calibration, sample handling, and personnel training. By following GLP, laboratories can maintain consistency, accuracy, and reliability in their research and testing processes, ultimately leading to trustworthy and valid results.

Submit
3. What is the term used to describes the act of inducing humane death in an animal?

Explanation

Euthanasia is the correct answer because it refers to the act of inducing humane death in an animal. This term is commonly used in veterinary medicine to describe the process of intentionally ending an animal's life to alleviate suffering or for other compassionate reasons. Anesthetize, on the other hand, refers to the act of administering anesthesia to an animal, while kill is a more general term that does not necessarily imply a humane death. Therefore, neither anesthetize nor kill accurately describe the act of inducing humane death in an animal.

Submit
4. SOPs must be in place for the housing, feeding, handling, and care of animals in GLP studies.

Explanation

The statement is true because in order to ensure the validity and reliability of GLP (Good Laboratory Practice) studies, standard operating procedures (SOPs) must be established and followed for the housing, feeding, handling, and care of animals involved in these studies. This is important to maintain consistent and ethical treatment of the animals, as well as to minimize any potential confounding factors that could impact the study results. SOPs provide clear guidelines and protocols for the proper management and welfare of the animals, ensuring that they are treated in a humane and responsible manner throughout the study.

Submit
5. Which of the following will prevent cross-contamination within a facility ?

Explanation

Wearing protective clothing, separating quarantine animals from study animals, and disinfecting equipment are all measures that can prevent cross-contamination within a facility. Wearing protective clothing, such as gloves and lab coats, can prevent the transfer of contaminants from one area to another. Separating quarantine animals from study animals ensures that any potential pathogens or diseases are contained and do not spread to healthy animals. Disinfecting equipment regularly helps to kill any bacteria or viruses that may be present, reducing the risk of contamination. Therefore, all of the above options are correct in preventing cross-contamination within a facility.

Submit
6. In the case  of animals traumatized due to fighting animal care techinicians can__________without the knowledge and/or supervision of the facility veterinarian,

Explanation

In the case of animals traumatized due to fighting, it is necessary to separate the fighting animals. This is important to prevent further harm or injuries to the animals involved. Animal care technicians can do this without the knowledge and/or supervision of the facility veterinarian as it is a basic and immediate action that needs to be taken to ensure the safety and well-being of the animals.

Submit
7.               What is a Abscesses ?

Explanation

Abscesses are swellings filled with pus that occur as a result of bacteria being deposited deep under the skin at the site of a trauma. Pus is a mixture of dead bacteria, liquefied tissue, and white blood cells. This answer accurately describes the characteristics and formation of abscesses.

Submit
8. Thoracic compression is the preferred euthanasia method for birds

Explanation

The statement "Thoracic compression is the preferred euthanasia method for birds" is false. Thoracic compression involves applying pressure to the bird's chest, which can cause pain and distress. It is not considered a humane method of euthanasia for birds. Instead, methods such as carbon dioxide inhalation or intravenous injection of euthanasia solution are recommended for a more humane and painless euthanasia process.

Submit
9.      Direct immersion of an animal into formalin is good means of euthanasia.

Explanation

Direct immersion of an animal into formalin is not a good means of euthanasia. Formalin is a solution of formaldehyde, which is a toxic substance. Direct immersion into formalin can cause severe pain and distress to the animal, making it an inhumane method of euthanasia. There are other more humane methods available for euthanizing animals that should be used instead.

Submit
10. The  IACUC ___________

Explanation

The IACUC (Institutional Animal Care and Use Committee) is responsible for reviewing animal use protocols, conducting inspections of animal facilities, and reviewing institutional animal use programs every six months. Additionally, the IACUC can serve as an information and resource liaison on animal welfare and research concerns.

Submit
11. Identify the route of injection that provides the fatest abosrbtion into the body system

Explanation

The route of injection that provides the fastest absorption into the body system is intravenous (I.V.) injection. This method involves injecting the substance directly into a vein, allowing it to quickly enter the bloodstream and be distributed throughout the body. Compared to other routes such as intraperitoneal (I.P.), subcutaneous (S.C.), and intradermal (I.D.) injections, the I.V. route provides the most immediate and efficient absorption.

Submit
12.      This species of rodent should be provided with a dust bath several times weekly  

Explanation

Chinchillas should be provided with a dust bath several times weekly because they have dense fur that doesn't allow water to penetrate easily. Dust baths help to keep their fur clean and healthy by removing excess oil and moisture.

Submit
13. When animals touch one another and transmit disease they are said to hae had _________contact.

Explanation

When animals touch one another and transmit disease, it is considered direct contact because the disease is directly transmitted from one animal to another through physical contact. Indirect contact would involve the transmission of the disease through an intermediate object or surface, while active and passive contacts are not specific to disease transmission through physical touch.

Submit
14.       What are the 3R's ?

Explanation

These principles were first described by William Russell and Rex Burch in 1959 to encourage more humane and ethical treatment of animals in scientific research.

Reduction: This involves minimizing the number of animals used in experiments without compromising scientific validity or the quality of research. Scientists should use the fewest number of animals possible to achieve their research objectives.



Replacement: This principle promotes the use of alternative methods, such as in vitro testing, computer modeling, or using lower organisms like bacteria or plants, to replace the use of animals in experiments whenever possible.



Refinement: This principle encourages researchers to modify experimental procedures and improve animal welfare to minimize any suffering or distress experienced by animals used in research. Refinements can include using better pain management techniques, improving housing conditions, and implementing more humane experimental methods.



By adopting these 3R's, researchers aim to minimize the use of animals in scientific experiments and ensure that any animals involved are treated with care, respect, and compassion.

Submit
15.                     What is Zoonosis ?  

Explanation

Zoonosis refers to a disease that can be transmitted from humans to animals or animals to humans. This means that the disease can be passed between different species, posing a potential risk to both humans and animals. It highlights the importance of understanding and managing diseases that have the potential to cross species boundaries.

Submit
16. The animal census is a ________

Explanation

The animal census is a method of record keeping. This means that it is a system or process used to document and maintain information about animals. A census involves counting and collecting data about a population, in this case, animals. By conducting an animal census, information such as population size, species distribution, and other relevant data can be recorded and used for various purposes such as conservation, research, and management.

Submit
17.     What is the most common breed of rabbit used in laboratory research?

Explanation

The most common breed of rabbit used in laboratory research is the New Zealand White.

Submit
18.      If a rabbits hindquarters are not supported this can happen ?

Explanation

If a rabbit's hindquarters are not supported, it can lead to fractures of the caudal lumbar spine. This is because the hindquarters of a rabbit are crucial for maintaining its balance and mobility. Without proper support, the weight and stress on the spine can cause fractures in the caudal lumbar region, which refers to the lower part of the spine near the tail. Fractures in this area can be extremely painful and may result in loss of movement and function in the hind limbs.

Submit
19. All mammals have a_____ chambered heart

Explanation

The statement "All mammals have a four-chambered heart" is a well-known fact in biology. Mammals, including humans, have a four-chambered heart consisting of two atria and two ventricles. This four-chambered structure allows for efficient separation of oxygenated and deoxygenated blood, ensuring proper circulation throughout the body.

Submit
20. What does the acronym PHS stand for?

Explanation

The acronym PHS stands for Public Health Service. This is a government agency that is responsible for protecting and promoting the health of the American people. The Public Health Service works to prevent and control diseases, improve access to healthcare, and conduct research to advance public health knowledge.

Submit
21.              What is the definition of moribund?

Explanation

The definition of moribund is "approaching death; in a dying state". This means that something or someone is near the end of their life and is in a state of decline or decay. It implies that death is imminent and that there is little hope for recovery or improvement. This definition is distinct from "approaching sickness" or "having trouble giving birth", as these phrases do not accurately capture the meaning of moribund.

Submit
22. Which of the following are methods of setrilization ?

Explanation

All of the methods mentioned - chemical, dry heat, moist heat, and radiation - are valid methods of sterilization. Chemical sterilization involves the use of chemicals to kill microorganisms, dry heat sterilization involves the use of high temperatures in an oven or hot air, moist heat sterilization involves the use of steam under pressure, and radiation sterilization involves the use of ionizing radiation to kill microorganisms. Therefore, all of the methods listed are viable options for sterilization.

Submit
23. Of the following solutions, ___________are usually reserved for use on floors, tables, cages, and other surfaces to reduce the load of organisms.

Explanation

Disinfectants are usually reserved for use on floors, tables, cages, and other surfaces to reduce the load of organisms. Disinfectants are chemical agents that are used to kill or inactivate microorganisms on surfaces, thereby reducing the risk of infection. They are often used in settings such as hospitals, laboratories, and homes to maintain cleanliness and prevent the spread of harmful bacteria, viruses, and fungi. Antiseptics, on the other hand, are used on living tissues to prevent infection, sterilants are used to completely eliminate all forms of life, and glutaraldehydes are a type of sterilant commonly used in medical and laboratory settings.

Submit
24.                Tied dairy cattle should have daily exercise in a yard

Explanation

Tied dairy cattle should have daily exercise in a yard. This means that it is necessary for dairy cattle that are tied up to be given daily exercise in a yard. This statement is true.

Submit
25. The IACUC must conduct inspections of the animals facilities and support areas at least one every ________months

Explanation

The IACUC must conduct inspections of the animal facilities and support areas at least once every six months. This ensures regular monitoring and evaluation of the conditions and welfare of the animals. Conducting inspections every three months would be too frequent, while inspections every twelve or twenty-four months would not provide adequate oversight. Therefore, the correct answer is six months.

Submit
26.     Helicobacter spp. are motile bacteria that inhabit _______in variety of species including mice, rats, hamsters, cats, dogs, humans, and other animals.

Explanation

Helicobacter spp. are motile bacteria that inhabit the gastrointestinal tract from the stomach to the colon in a variety of species including mice, rats, hamsters, cats, dogs, humans, and other animals.

Submit
27.        Unlike mice that will mate with many females gerbils are this and if they lose thier mate they generally will not accept another.

Explanation

Gerbils are monogamous because they typically mate with only one partner and do not accept another mate if they lose their current one. This behavior is different from mice, which are polygamous and will mate with multiple females. The term "inbred" does not apply to the mating behavior of gerbils, so it is not the correct answer. Therefore, the correct answer is monogamous.

Submit
28.       The best place to take blood collection in a rabbit is ?

Explanation

Rabbits have prominent veins in their ears, making it the best place to collect blood. The ear veins are easily accessible and can be safely punctured to collect blood samples without causing much discomfort to the rabbit. Collecting blood from the front foot or jugular vein can be more challenging and may cause more stress to the rabbit. The eyes are not a suitable place for blood collection in rabbits.

Submit
29. Some of the extra requirments of immunocompromised animals are _________

Explanation

Immunocompromised animals have weakened immune systems, making them more susceptible to infections and diseases. Therefore, they require extra precautions and specialized care. Micro-isolator housing is necessary to provide a sterile environment and prevent the entry of pathogens. Acidified water helps maintain a proper pH balance in the animals' bodies, reducing the risk of bacterial growth. Sterilized housing ensures that the animals are kept in a clean and germ-free environment. Therefore, all of the mentioned requirements (micro-isolator housing, acidified water, sterilized housing) are necessary for the well-being and health of immunocompromised animals.

Submit
30. Platelets are essential for _______

Explanation

Platelets are essential for clotting blood because they play a crucial role in the formation of blood clots. When a blood vessel is damaged, platelets are activated and aggregate at the site of injury to form a clot, which helps to stop bleeding. Platelets release various clotting factors that initiate a cascade of reactions leading to the formation of fibrin, a protein that forms a mesh-like structure to reinforce the clot. Without platelets, the body would have difficulty in controlling bleeding, leading to excessive blood loss and potential life-threatening situations.

Submit
31. Sexual reproduction is conrolled by __________.

Explanation

Sexual reproduction is a complex process that involves the coordination of various hormones and chemicals in the body. These hormones, such as estrogen and testosterone, play a crucial role in regulating the development and functioning of the reproductive organs. The pituitary gland, often referred to as the "master gland," releases hormones that stimulate the gonads (ovaries in females and testes in males) to produce sex hormones. Therefore, all of the options mentioned - hormones, chemicals in the body, pituitary gland, and gonads - are correct as they are all involved in controlling sexual reproduction.

Submit
32. Tricaine methane sulfonate (TMS, MS 222)  is used to euthanasia for

Explanation

Tricaine methane sulfonate (TMS, MS 222) is commonly used as an anesthetic agent for fish and amphibians. It is used to induce a state of unconsciousness and ultimately euthanize these animals in a humane manner. This method is preferred for aquatic species as it allows for easy administration and is effective in minimizing pain and distress during euthanasia. However, it is not commonly used for euthanasia in dogs, cats, mice, rats, or nonhuman primates.

Submit
33. The primary ganting agency through which the untied states conducts and supports biomedical research is the

Explanation

The primary funding agency through which the United States conducts and supports biomedical research is the National Institutes of Health (NIH). The NIH is a part of the U.S. Department of Health and Human Services and is responsible for funding and conducting research aimed at improving public health and reducing the burden of disease. The NIH provides financial support for various research projects, including basic, clinical, and translational research, as well as training and career development programs for researchers. It is composed of 27 institutes and centers, each focused on specific areas of health and disease, such as cancer, heart disease, neurological disorders, and infectious diseases. By funding cutting-edge biomedical research, the NIH plays a vital role in advancing our understanding of human health and developing new treatments and interventions for a wide range of medical conditions.

Submit
34. Dystocia is a condition which may be encountered ___________

Explanation

Dystocia is a condition that refers to difficult or prolonged labor during childbirth. It can occur in any species during parturition, which is the process of giving birth. This means that dystocia can be encountered in various animals, including humans, dogs, cats, horses, etc., when they are going through the process of giving birth. The other options provided in the question (lack of kindling material in rabbits, vitamin B6 deficiency in laboratory animals, and lack of medical/surgical treatment) do not accurately describe the general occurrence of dystocia in all species during parturition.

Submit
35. The gauge of the needle refers to the ________

Explanation

The gauge of the needle refers to its diameter. The gauge is a standardized measurement that indicates the size of the needle's opening. A smaller gauge number corresponds to a larger needle diameter, while a larger gauge number corresponds to a smaller needle diameter. The gauge of the needle is an important factor to consider when choosing the appropriate needle for a specific medical procedure or injection.

Submit
36. Samples of all tissues collected during a necropsy are prserved for histopathology by placing them in_____________ 

Explanation

During a necropsy, tissues are collected for histopathology, which involves examining the tissue under a microscope to study any abnormalities or diseases. To preserve the tissues and prevent decomposition, they are placed in a solution called 10% buffered formalin. This solution contains formaldehyde, which acts as a fixative to prevent the degradation of cellular structures. It also helps to maintain the tissue's original structure and allows for better visualization and analysis during histopathological examination.

Submit
37. Painful Procedures can be performed on unanesthetized animals as long as they have been paralyzed by chemical agents

Explanation

The statement is false because while paralysis may temporarily prevent an animal from showing physical signs of pain, it does not eliminate the actual experience of pain. Anesthetizing animals is necessary to ensure that they do not feel pain during procedures.

Submit
38. What is the only acceptable methods of euthanasia listed for nonhuman primates?

Explanation

Barbiturates are the only acceptable method of euthanasia listed for nonhuman primates. Barbiturates are commonly used in euthanasia as they induce a painless and peaceful death. They work by depressing the central nervous system, causing loss of consciousness and eventually respiratory arrest. Other methods such as carbon dioxide, MS222, and ammonia are not recommended for euthanizing nonhuman primates as they may cause unnecessary pain and distress.

Submit
39. Per diem cost are the expense required to maintain one animal for _____________

Explanation

Per diem costs refer to the daily expenses required to maintain one animal. This means that the cost is calculated on a daily basis, regardless of the duration of time the animal is maintained in the facility. Therefore, the correct answer is "one day."

Submit
40. The most desirable site for an IM injection is _________

Explanation

The most desirable site for an IM injection is a large muscle mass because it allows for better absorption and distribution of the medication. A large muscle mass has a greater blood supply, which helps in the efficient delivery of the medication to the bloodstream. It also reduces the risk of damage to surrounding structures and nerves. Additionally, injecting into a large muscle mass ensures that the medication is not injected into a joint or a blood vessel, which could cause complications.

Submit
41. Identify the zoonotic disease most accociated with cats.

Explanation

Toxoplasmosis is the zoonotic disease most associated with cats. It is caused by the parasite Toxoplasma gondii, which can be found in the feces of infected cats. Humans can become infected by accidentally ingesting the parasite through contaminated food, water, or soil. Pregnant women and individuals with weakened immune systems are particularly at risk. While most people with toxoplasmosis experience mild flu-like symptoms or no symptoms at all, it can cause severe complications in certain cases. Therefore, it is important to practice good hygiene and take precautions when handling cat litter or interacting with cats to prevent the transmission of toxoplasmosis.

Submit
42. A cage card is considered raw data when you measure the animal's body weight and record its weight on the card.

Explanation

When you measure the animal's body weight and record it on the cage card, you are collecting objective information directly from the animal. This data is considered raw because it has not been processed or analyzed in any way. It is a factual observation that can be used for further analysis or comparison. Therefore, the statement "A cage card is considered raw data when you measure the animal's body weight and record its weight on the card" is true.

Submit
43.             For death to be painless and distress—free, _____ should precede loss of motor activity (muscle movement).  

Explanation

Loss of consciousness is the correct answer because when a person loses consciousness, they are no longer aware of their surroundings or experiencing any pain or distress. Loss of consciousness precedes the loss of motor activity, which means that before the person's muscles stop moving, they first lose consciousness, ensuring that the process of dying is painless and distress-free.

Submit
44. When disease transmitted through the air (airbone or aerosol transmission) the animals is said to have had______________ contact with the infected source.

Explanation

When a disease is transmitted through the air, the animal is said to have had indirect contact with the infected source. This means that the disease is not transmitted through direct physical contact with the infected source, but rather through the air that has been contaminated with the infectious agents. This can occur through respiratory droplets or through aerosols that contain the pathogens.

Submit
45. When performing the initial scrub of the surgical area ___________is the only method which is acceptable

Explanation

not-available-via-ai

Submit
46. If animals are to be euthanized at the end of the study, the method of euthanasia must be in accordance with the guidlines (Panel on Euthanasia set up by the___________.

Explanation

The correct answer is AVMA (American Veterinary Medical Association). The AVMA is an organization that provides guidelines and standards for the humane euthanasia of animals. They have a panel specifically dedicated to euthanasia and provide recommendations on the appropriate methods to be used.

Submit
47. A condition in rodents caused by high temperaturs and low relative humidity is __________

Explanation

Ring tail is a condition in rodents that is caused by high temperatures and low relative humidity. This condition affects the tail of the rodent, causing it to become dry, brittle, and develop a ring-like appearance. This can lead to discomfort and potential health issues for the rodent.

Submit
48.                These are forms of enrichments for ferrets ?

Explanation

Ferrets are social animals that require mental and physical stimulation. Playmates provide social interaction and companionship for ferrets. Toys help to keep them entertained and mentally stimulated. Climbing opportunities allow ferrets to exercise and explore their environment. Interaction with humans is important for bonding and socialization. Therefore, playmate, toys, climbing opportunities, and interaction with humans are all forms of enrichment that are beneficial for ferrets.

Submit
49.       More than any other laboratory animal group these animals must be regarded as potential sources of zoonotic disease.

Explanation

Primates must be regarded as potential sources of zoonotic disease more than any other laboratory animal group. This is because primates share genetic similarities with humans, making them more likely to transmit diseases to humans. Additionally, primates are often used in biomedical research, which increases their exposure to various pathogens that could potentially be transmitted to humans. Therefore, it is important to take extra precautions when working with primates in order to minimize the risk of zoonotic disease transmission.

Submit
50. Respiration ____________.

Explanation

The correct answer is "all of the above". Respiration is a process that involves the exchange of gases between an organism and its environment. It can occur in various organs such as the lungs and gills. Additionally, respiration is a mechanical process that relies on pressure gradients between tissues and blood. Therefore, all of the given statements are true and encompass the concept of respiration.

Submit
51.    Which of these is an inbred rat strains ?

Explanation

Fisher F344 is an inbred rat strain because it is a specific line of rats that have been bred for many generations to have a uniform genetic makeup. This means that all individuals within the Fisher F344 strain are genetically identical, making them useful for scientific research as they can be used to study the effects of specific genes or genetic variations on various traits and diseases. Norway rat, Rodent, and Rattus are not inbred rat strains as they refer to different species or broader categories that include multiple genetic variations.

Submit
52.               If working with nonhuman primates  the recommended personal protection is?

Explanation

When working with nonhuman primates, it is recommended to use rubber gloves, a face mask, goggles, and full-length arm protection. This is because nonhuman primates can carry and transmit various diseases, including those that can be transmitted through direct contact, respiratory droplets, or bodily fluids. Therefore, wearing this level of personal protection can help minimize the risk of exposure and ensure the safety of the individual working with the animals.

Submit
53. When giving an intramuscular injection in the hind limb, care must be taken to avoid what structures

Explanation

When giving an intramuscular injection in the hind limb, care must be taken to avoid the femoral vein, femoral artery, and femoral nerve. These structures are all located in the hind limb and can be damaged if not avoided during the injection. Damage to the femoral vein can lead to bleeding, damage to the femoral artery can result in significant bleeding, and damage to the femoral nerve can cause pain and loss of function in the limb. Therefore, it is important to be cautious and avoid all of these structures when administering an intramuscular injection in the hind limb.

Submit
54. Which part of the mouse model BALB/c StCrl p GF (F83) is the strain symbol?

Explanation

The strain symbol in the mouse model BALB/c StCrl p GF (F83) is BALB.

Submit
55. Consult with a veterinarian who has the appropriate _____, and ____ for the species to ensure proper euthanasia procedures are used.

Explanation

The answer "Training; expertise" is correct because consulting with a veterinarian who has the appropriate training and expertise is crucial to ensure proper euthanasia procedures are followed. Euthanasia is a sensitive and delicate procedure that requires specific knowledge and skills to be carried out safely and compassionately. Therefore, it is important to seek guidance from a veterinarian who has received proper training and has the necessary expertise in euthanasia procedures for the specific species involved.

Submit
56. The integumentary system is comprised of _______

Explanation

The integumentary system is comprised of the skin. The skin is the largest organ of the body and is responsible for protecting the underlying tissues and organs, regulating body temperature, and sensing touch, pressure, and pain. It also helps in the production of vitamin D and plays a role in the immune system by acting as a barrier against pathogens.

Submit
57. Oxygen and carbon dioxide are exchanged between the blood and the air in what anatomical structure of the lungs ?

Explanation

Oxygen and carbon dioxide are exchanged between the blood and the air in the alveoli of the lungs. The alveoli are small air sacs located at the end of the bronchioles. They have thin walls and a large surface area, allowing for efficient gas exchange. Oxygen from the air diffuses into the bloodstream, while carbon dioxide, a waste product, diffuses out of the bloodstream into the alveoli to be exhaled. The bronchi, trachea, and bronchioles are all part of the respiratory system, but the actual exchange of gases occurs in the alveoli.

Submit
58. How often should you clean dog and other large animals cages or stalls ?

Explanation

Daily cleaning of dog and other large animal cages or stalls is necessary to maintain their hygiene and prevent the buildup of waste, bacteria, and odors. Animals produce waste regularly, and leaving it uncleaned for longer periods can lead to health issues and discomfort for the animals. Daily cleaning also helps to ensure a clean and safe environment for both the animals and their caretakers.

Submit
59. Research institutions provide The Public Health Service with a signed agreement that outlines the institution complies with all aspects of human animal care as described in the PHS Policy. This agreement is called the _____________Assurance

Explanation

Research institutions provide The Public Health Service with a signed agreement that outlines the institution complies with all aspects of human animal care as described in the PHS Policy. This agreement is called the Animal Welfare Assurance.

Submit
60.                   For non human primates this plan must be developed and documented and adhered to.

Explanation

The correct answer is "environmental enhancement" because the sentence states that a plan must be developed and documented for non-human primates, and this plan must also be adhered to. The term "environmental enhancement" suggests that the plan should focus on improving or enhancing the environment for these primates, which is in line with the idea of developing and adhering to a plan for their well-being.

Submit
61.        Sneezing and the presence of a serous to mucopurulent nasal discharge characterize the upper respiratory form of pasteurellosis which is also know as ?  

Explanation

The correct answer is "Snuffles." Sneezing and the presence of a serous to mucopurulent nasal discharge are symptoms of the upper respiratory form of pasteurellosis, which is commonly known as snuffles. "Running nose," "wet nose," and "sneezes" are not specific terms used to describe this condition.

Submit
62. What does the acronym TPR stand for ?

Explanation

The acronym TPR stands for Temperature, Pulse, and Respiration. This refers to the three vital signs that are commonly monitored in medical settings. Temperature measures the body's internal heat level, pulse measures the heart rate, and respiration measures the breathing rate. Monitoring these vital signs is important in assessing a person's overall health and detecting any abnormalities or changes that may indicate a medical condition.

Submit
63. The condition where no living thing organisms are present on a surface is termed____________

Explanation

The term "sterile" refers to a condition where no living organisms, including microorganisms, are present on a surface. This means that the surface has been completely free from any form of life, ensuring a high level of cleanliness and absence of potential pathogens. "Sanitized" and "disinfected" refer to processes that reduce the number of microorganisms on a surface, while "decontaminated" refers to the removal or neutralization of harmful substances. Therefore, "sterile" is the most appropriate term to describe the condition where no living organisms are present on a surface.

Submit
64.            Guinea pigs requires a dietary sources of this vitamin

Explanation

Guinea pigs require a dietary source of vitamin C because they are unable to synthesize it on their own. Vitamin C is essential for their overall health and well-being as it helps in the formation and maintenance of connective tissues, wound healing, and the proper functioning of the immune system. Without enough vitamin C in their diet, guinea pigs can develop a condition called scurvy, which can lead to various health problems. Therefore, providing guinea pigs with a sufficient amount of vitamin C through their diet is crucial for their optimal health.

Submit
65. If a 4% drug solution were to be administered at a dose rate of 1 ml per 5 pounds of body weight and the animal weighs 30 lbs, How much drug and volume would be given ? This question asks for drug amount (mg/grams) but the answers are in volume.

Explanation

The correct answer is 240 mg; 6 ml. This is because the question asks for the drug amount (mg/grams) and the given dose rate is 1 ml per 5 pounds of body weight. Since the animal weighs 30 lbs, we can calculate the drug amount by multiplying the dose rate (1 ml) by the weight (30 lbs) divided by 5 (since 1 ml is given for every 5 pounds). This gives us 6 ml of the drug. Additionally, since the drug solution is 4%, we can calculate the drug amount by multiplying the volume (6 ml) by the concentration (4%). This gives us 240 mg of the drug.

Submit
66. What agency is responsible for determining whether new medical devices (like artificial joints and cardiac pacemakers) are safe and effective befroe they are approved for sale in the United States?

Explanation

The Food and Drug Administration (FDA) is responsible for determining whether new medical devices, such as artificial joints and cardiac pacemakers, are safe and effective before they are approved for sale in the United States. The FDA is a government agency that regulates and oversees the safety and efficacy of drugs, medical devices, food, cosmetics, and other products. They conduct rigorous testing and review processes to ensure that medical devices meet the necessary standards before they can be sold to the public.

Submit
67. A rabbit has a total blood volume percentage of 6%. What would be the total blood volume for a rabbit weighing 3 kilograms?

Explanation



To calculate the total blood volume for a 3kg rabbit with a blood volume percentage of 6%:

Total blood volume = (Weight of the rabbit in kg) × (Blood volume percentage)

Total blood volume = 3 kg × 6% = 3 kg × 0.06 = 0.18 kg

Now, we need to convert the blood volume from kilograms to milliliters.

Since 1 kg = 1000 grams and 1 gram = 1 milliliter for water:

Total blood volume = 0.18 kg × 1000 ml/kg = 180 ml

So, the total blood volume for a 3kg rabbit would be 180 ml.

Therefore, the correct answer is 180 ml.
Submit
68.              To avoid getting bitten by a hamster it is important to make sure the hamster is this ?  

Explanation

To avoid getting bitten by a hamster, it is important to make sure that the hamster is awake and expects to be picked up. This means that the hamster is alert and aware of its surroundings, and it is comfortable with being handled. If the hamster is asleep or turned away from you, it may be startled or feel threatened when you try to pick it up, increasing the risk of being bitten. Therefore, it is crucial to handle a hamster when it is awake and shows signs of being ready to be picked up.

Submit
69. A typical NIH grant provides money for a ________ year period

Explanation

A typical NIH grant provides money for a three-year period. This means that the grant recipient will receive funding for their research project for a duration of three years. During this time, they can utilize the funds to conduct their research, collect data, and make progress towards their scientific goals. The three-year period allows researchers to have a sufficient amount of time to carry out their studies and potentially make significant contributions to their field of study.

Submit
70.   In some research and teaching situations, it is necessary to house beef cattle under intensive laboratory conditions. Cattle may be kept in metabolism stalls, stanchions, respiration chambers, or environmental chambers. What should be ensured when housing cattle in such facilities?

Explanation

The correct answer states that housing cattle in intensive laboratory conditions should be avoided unless it is necessary for the experimental protocol. This suggests that the normal way to house cattle is not in such facilities and that it is only done when there is a specific need for research or teaching purposes.

Submit
71.             Guinea pigs should be bred before how old?

Explanation

Guinea pigs should be bred before they reach 7 months old. This is because after this age, female guinea pigs become less fertile and may experience complications during pregnancy and birth. Breeding them before this age ensures healthier and more successful pregnancies.

Submit
72. Which of the following responsibilities is NOT typically associated with a Laboratory Animal Technician?

Explanation

Laboratory Animal Technicians are responsible for administering medications, cleaning and maintaining animal habitats, and monitoring the health and well-being of lab animals. Conducting independent scientific research is typically the role of scientists or researchers, not technicians, although technicians may assist in research under the supervision of a scientist.

Submit
73. The receptive stance (fixed position with hindquarters elevated and tail to one side) of the female in estrus is known as ___________.

Explanation

The receptive stance of the female in estrus, characterized by a fixed position with hindquarters elevated and tail to one side, is known as lordosis. This is a natural behavior displayed by female mammals during their fertile period to signal their readiness to mate. Hyperkaratosis refers to the thickening of the skin, anestrus is a period of sexual inactivity, and follicular stimulation involves the growth and development of ovarian follicles.

Submit
74. The PHS Policy includes the Health Research Extension Act of 1985 and the ___.

Explanation

The correct answer is "US Government Principles for the Utilization in Testing, Research, and Training." The PHS Policy is a set of regulations and guidelines that govern the use of animals in research funded by the Public Health Service (PHS). It includes the Health Research Extension Act of 1985, which requires institutions to establish Institutional Animal Care and Use Committees (IACUCs) to oversee the use of animals in research. Additionally, the PHS Policy incorporates the US Government Principles for the Utilization in Testing, Research, and Training, which outline ethical considerations and guidelines for the use of animals in research.

Submit
75.
  1. Unplanned changes to a procedure during the conduct of a study are called______.
    1.  

Explanation

During the conduct of a study, unplanned changes to a procedure are referred to as deviations. These deviations may occur due to unforeseen circumstances or errors, and they can impact the integrity and reliability of the study results. It is important to document and report these deviations to ensure transparency and to assess their potential impact on the study outcomes.

Submit
76. Thoracic compression is the preferred euthanasia method for birds

Explanation

Thoracic compression is not the preferred euthanasia method for birds. This method involves applying pressure to the bird's chest to cause death, which can be distressing and painful for the bird. Instead, the preferred euthanasia method for birds is considered to be inhalant anesthesia followed by cervical dislocation or decapitation, as these methods are considered to be more humane and quick.

Submit
77. An endotracheal tube is used to ___________

Explanation

An endotracheal tube is a medical device that is used to deliver oxygen directly into the trachea, ensuring that the patient receives an adequate supply of oxygen. It is also used to prevent the aspiration of foreign material, such as saliva or vomit, into the lungs, which can lead to serious complications. Additionally, an endotracheal tube can serve as a resuscitation tool by allowing for the administration of medications or the performance of emergency procedures, such as cardiopulmonary resuscitation (CPR). Therefore, the correct answer is "all of the above" as an endotracheal tube can be used for all these purposes.

Submit
78.            Adjunctive methods are those methods considered acceptable as the sole method of euthanasia

Explanation

Adjunctive methods are not considered acceptable as the sole method of euthanasia. They are additional methods that can be used in conjunction with other methods to ensure a more humane and effective euthanasia process. The correct answer is False, indicating that adjunctive methods are not acceptable as the sole method of euthanasia.

Submit
79. According to the Health Research Extension Act of 1985, the IACUC must inspect facilities at least ___.

Explanation

According to the Health Research Extension Act of 1985, the IACUC must inspect facilities at least semi-annually. This means that the inspections must occur twice a year. This ensures that the facilities are regularly monitored and maintained to meet the necessary standards for the well-being of animals involved in research.

Submit
80. The lymphatic system _________________

Explanation

The lymphatic system is responsible for regulating fluid balance between tissue and blood plasma. It helps to maintain the proper balance of fluids in the body by collecting excess fluid from the tissues and returning it to the bloodstream. This helps to prevent the accumulation of fluid and swelling in the tissues. Additionally, the lymphatic system plays a role in immune function by filtering and removing waste, toxins, and pathogens from the body.

Submit
81.           The most common health problems of nonhuman primates are _______________and ________________.

Explanation

Nonhuman primates are susceptible to various health problems, and two of the most common ones are bacterial enteritis and bacterial pneumonia. Bacterial enteritis refers to the inflammation of the intestine caused by bacterial infection, leading to symptoms like diarrhea and abdominal pain. Bacterial pneumonia, on the other hand, is an infection of the lungs caused by bacteria, resulting in symptoms such as coughing, difficulty breathing, and fever. These two conditions are prevalent among nonhuman primates and can significantly impact their health and well-being.

Submit
82.    Microwave irradiation requires a special irradiator

Explanation

Microwave irradiation requires a special irradiator because regular household microwaves are not designed to handle the specific requirements and safety measures needed for controlled and efficient irradiation. A special irradiator is necessary to ensure that the microwave energy is properly contained and directed towards the desired target, while also preventing any potential harm to the operator or the surrounding environment.

Submit
83. The total blood volume in an animal's body equals approximately _________% of its body weight

Explanation

The total blood volume in an animal's body is approximately 6% of its body weight. This means that for every kilogram of an animal's body weight, around 60 milliliters of blood is present. Blood volume is an important factor in maintaining homeostasis and ensuring proper oxygen and nutrient transport throughout the body.

Submit
84.   Cedar is not recommended bedding material for gerbils because it is irritating to the ______________

Explanation

Cedar is not recommended as bedding material for gerbils because it can cause irritation to their skin and mucous membranes.

Submit
85.                      This is the most common problem seen in group-housed primates

Explanation

Bite wounds are the most common problem seen in group-housed primates. This suggests that primates in group housing often engage in aggressive behavior and bite each other, resulting in injuries. This could be due to competition for resources, territorial disputes, or social hierarchy within the group. The presence of bite wounds indicates a potential issue with aggression and social dynamics in the primate group.

Submit
86. A purple top tube contains which anticoagulant?

Explanation

The correct answer is EDTA. EDTA stands for ethylenediaminetetraacetic acid, which is an anticoagulant commonly used in purple top tubes. It works by binding to calcium ions, which are necessary for blood clotting, thus preventing the blood from clotting. EDTA is used for tests that require whole blood or plasma, such as complete blood count (CBC), blood typing, and blood glucose testing. Sodium citrate is commonly used as an anticoagulant in light blue top tubes for coagulation tests, ACD (acid citrate dextrose) is used for preserving blood for blood transfusions, and heparin is used as an anticoagulant in green top tubes for certain chemistry tests.

Submit
87. The PHS Policy requires that all assurance records related directly to grant applications, research proposals and changes in research activites be maintianed for at least _____year(s)  after complection of an activity

Explanation

The PHS Policy mandates the maintenance of assurance records for a specific period after the completion of an activity. In this case, the correct answer is "three," indicating that these records must be kept for at least three years. This requirement ensures that there is a sufficient record of grant applications, research proposals, and changes in research activities for future reference and potential audits.

Submit
88. Which of these carry salmonella ?

Explanation

Birds and reptiles can carry and transmit salmonella. Salmonella is a type of bacteria that can cause food poisoning in humans. Dogs and cats, nonhuman primates and swine, and birds and cattle are not known to be carriers of salmonella.

Submit
89. AAALAC International __________________. (identify the false statement)

Explanation

AAALAC International is not a government-sponsored agency. It is a private, nonprofit organization that provides voluntary accreditation for animal care and use programs. It conducts site visits every three years and requires annual reports from its accredited facilities.

Submit
90.                    Most mammals can synthesize vitamin C but these two animals cannot?

Explanation

Primates and guinea pigs cannot synthesize vitamin C because they lack the enzyme L-gulonolactone oxidase, which is necessary for the synthesis of vitamin C in the body. This enzyme is present in most mammals, allowing them to produce their own vitamin C. However, primates and guinea pigs have lost the ability to produce this enzyme through evolution, making them unable to synthesize vitamin C and requiring them to obtain it through their diet.

Submit
91. If it costs $6000.00 per year to maintian 200 rats, what should the per diem be?

Explanation

The per diem should be .08 because it is the correct answer that satisfies the given information. The question states that it costs $6000.00 per year to maintain 200 rats. To find the per diem, we need to divide the total cost by the number of rats. $6000.00 divided by 200 rats equals $30.00 per rat per year. To find the per diem, we need to divide $30.00 by 365 days. This equals approximately .08, which is the correct answer.

Submit
92. Which of the following lab animal spcies does not prodice a good model for polygamous mating systems

Explanation

Gerbils do not produce a good model for polygamous mating systems because they are monogamous animals, meaning they form long-term pair bonds with a single partner. In polygamous mating systems, individuals have multiple mates, which is not the case for gerbils. Therefore, gerbils would not be suitable for studying the dynamics and behaviors associated with polygamous mating systems.

Submit
93. The addition of a male to a cage which has held only females, resulting in the initiation of estrus in the females at about three days is known as ________

Explanation

The Whitten effect refers to the phenomenon where the addition of a male to a cage that previously only housed females leads to the initiation of estrus in the females after approximately three days. This effect is commonly observed in rodent studies and is believed to be triggered by the presence of male pheromones, which synchronize the reproductive cycles of the females. This synchronization can increase the chances of successful mating and reproduction in the group.

Submit
94. There is another form of the Guide just for Farm animals used in research

Explanation

False. The "Guide" being referred to here is likely the "Guide for the Care and Use of Laboratory Animals," a publication by the National Research Council in the United States. This guide provides recommendations and guidelines for the humane care and use of animals in research, teaching, and testing. While it covers various species, including farm animals, there isn't a separate version of the Guide specifically dedicated to farm animals used in research. The principles and guidelines outlined in the Guide for the Care and Use of Laboratory Animals are intended to be applied to all animals used in research, regardless of species, to ensure their humane treatment and well-being. However, it is important to note that additional guidelines or regulations may exist at national, regional, or institutional levels to address specific concerns or requirements related to the use of farm animals or other specific species in research.

Submit
95. The left ventricle contracts, pumping blood to _______

Explanation

The left ventricle is responsible for pumping oxygenated blood to all the organs of the body. This is because the left ventricle receives oxygen-rich blood from the lungs and then contracts to propel this oxygenated blood into the aorta, which is the largest artery in the body. From the aorta, the oxygenated blood is distributed to all the organs and tissues, ensuring that they receive the necessary oxygen and nutrients for proper functioning. Therefore, the correct answer is all the organs of the body.

Submit
96. In goats, cattle, and sheep the breakdown of cellulose occurs _____________.

Explanation

In goats, cattle, and sheep, the breakdown of cellulose occurs in the rumen. The rumen is the first compartment of their multi-chambered stomach, where microbial fermentation takes place. This fermentation process allows the animals to break down cellulose, a complex carbohydrate found in plant cell walls, with the help of microorganisms such as bacteria and protozoa. The breakdown of cellulose in the rumen is essential for these animals to obtain nutrients from plant material and is a crucial step in their digestive process.

Submit
97. Tissue samples collected during necropsy should be "sectioned" or cut to a thickness no greater than ________to assure good fixation.

Explanation

During necropsy, tissue samples are collected for further examination. To ensure proper fixation, the tissue samples need to be sectioned or cut to a specific thickness. The correct answer of 1 cm is the most appropriate choice because it allows for optimal fixation of the tissue samples. Cutting the samples to a thickness greater than 1 cm may result in inadequate fixation, which can affect the accuracy of the examination and analysis of the tissues.

Submit
98. Which agency enforces the Toxic Substances Control Act (TSCA) relating to industrial chemicals?

Explanation

The correct answer is EPA. The Environmental Protection Agency (EPA) is responsible for enforcing the Toxic Substances Control Act (TSCA) relating to industrial chemicals. The TSCA gives the EPA the authority to regulate the manufacture, distribution, and use of chemicals in order to protect human health and the environment. The EPA sets standards, conducts inspections, and enforces regulations to ensure compliance with the TSCA.

Submit
99.  Fish have low tolerance for CO2, so it is a rapid method of euthanasia for these animals.

Explanation

Fish actually have a high tolerance for CO2, so it is not a rapid method of euthanasia for these animals.

Submit
100. Besides dogs and cats, which other animal must be vaccinated for rabies?

Explanation

The correct answer is "canine distemper" because the question is asking which vaccination is required for an animal along with dogs and cats. Canine distemper is a highly contagious viral disease that affects dogs, and it is important to vaccinate other animals, such as ferrets and raccoons, to prevent the spread of the disease. The other options, herpes B and flu, are not relevant to the question and do not need to be vaccinated along with dogs and cats.

Submit
101. Nude mice lack a _____________

Explanation

Nude mice lack a thymus gland, which is a primary lymphoid organ responsible for the development and maturation of T cells. Without a thymus gland, nude mice have impaired immune responses, making them useful models for studying immune system function and transplantation. The other options (thyroid gland, pituitary gland, adrenal gland) are not directly related to the immune system and do not have the same impact on immune responses as the thymus gland.

Submit
102. Of four stages of estrus which is defined as that where follicle development takes place?

Explanation

Proestrus is the stage of estrus where follicle development takes place. During this stage, the follicles in the ovaries start to develop and mature, preparing for ovulation. This is the initial phase of the estrus cycle and is characterized by an increase in estrogen levels, which leads to the development of a receptive uterus and the onset of behavioral changes in the female.

Submit
103.                        All humans working with primates must be tested for this ?

Explanation

All humans working with primates must be tested for tuberculosis because it is a highly contagious disease that can be transmitted from primates to humans. Tuberculosis is caused by bacteria that primarily affect the lungs, but can also affect other parts of the body. It is important for humans working with primates to be tested for tuberculosis in order to prevent the spread of the disease and protect both the primates and themselves. Rabies and Herpes B are also potential risks when working with primates, but they are not specifically mentioned in the question.

Submit
104. An inanimate object that provides a mechanical means of disease transmission is called_____________

Explanation

A fomite is an inanimate object that can harbor and transmit disease-causing microorganisms. Unlike a vector, which is usually a living organism like a mosquito or tick, a fomite does not actively transmit the disease but can passively transfer pathogens from one person or surface to another. This can occur through direct contact or by touching contaminated objects or surfaces. Examples of fomites include doorknobs, phones, and utensils. Therefore, the correct answer for this question is fomite.

Submit
105.             How many chapters are in the Guide for the care and use of laboratory animals ?

Explanation

The correct answer is 5 because the question is asking for the number of chapters in the Guide for the care and use of laboratory animals. The answer 5 indicates that there are 5 chapters in the guide.

Submit
106. The most information about temperature in a secondary enclsoure of animal facility is generated from a ________________.

Explanation

A minimum/maximum thermometer is the most suitable instrument for generating the most information about temperature in a secondary enclosure of an animal facility. This type of thermometer records both the lowest and highest temperatures reached over a specific period, providing a comprehensive understanding of temperature fluctuations. An anemometer measures wind speed, a hygrometer measures humidity, and a standard thermometer only provides a current temperature reading.

Submit
107.        The most common cause of disease in chinchillas relates to this?

Explanation

Husbandry and feeding mistakes are the most common cause of disease in chinchillas. This can include improper housing conditions, inadequate nutrition, and incorrect handling. These mistakes can weaken the chinchilla's immune system and make them more susceptible to various diseases and infections. It is important for chinchilla owners to provide proper care and nutrition to ensure the health and well-being of their pets.

Submit
108.      This species of rodent is more solitary than social ?

Explanation

Hamsters are more solitary than social compared to other rodents such as mice, rats, and gerbils. They are known to prefer living alone and are less likely to interact or socialize with other members of their species. This behavior is different from mice, rats, and gerbils, which are more social and tend to live in groups or colonies. Therefore, the correct answer is Hamsters.

Submit
109.           Of the two major groups of nonhuman primates _______________are closery related to humans having more zoonotic diseases than ___________ which is more closely related to dogs and rodents are generally not transmissible to humans.

Explanation

Old world primates are more closely related to humans and have more zoonotic diseases compared to new world primates. This is because old world primates, such as apes and monkeys, share a more recent common ancestor with humans and have similar genetic and physiological characteristics. New world primates, on the other hand, are more closely related to dogs and rodents and therefore have fewer zoonotic diseases that can be transmitted to humans.

Submit
110. An institution where each department keeps and uses animals in its own animal facility using its own operating budget is___________

Explanation

Decentralized is the correct answer because in this type of institution, each department has its own animal facility and operates independently with its own budget. This means that decision-making and control over the animals are distributed among the different departments, rather than being centralized in one central authority.

Submit
111.                            _____ is an abnormality with a rabbit is unable to abduct one or more limbs.

Explanation

Splay leg is an abnormality where a rabbit is unable to abduct one or more limbs. This condition causes the legs to splay outwards, making it difficult for the rabbit to walk or hop properly. "Broke leg" refers to a fracture in the leg bone, "broke back" refers to a fracture in the spinal column, and "all above" is not a specific condition. Therefore, the correct answer is "Splay leg".

Submit
112. The recommended temperature ranges for secondary enclosures for most laboratory species is 19-26 degrees Celsius. This translates to __________________degrees Fahrenheit.

Explanation

The recommended temperature range for secondary enclosures for most laboratory species is 19-26 degrees Celsius. To convert this to Fahrenheit, we can use the formula F = (C * 9/5) + 32. By plugging in the values, we get 66-79 degrees Fahrenheit.

Submit
113.      When chinchillas are handled roughly become agitated during handling or fight the fur may come out in patches this know as ?  

Explanation

When chinchillas are handled roughly, become agitated during handling, or fight, their fur may come out in patches. This is known as fur slip.

Submit
114. What government agency is responsible for the general administration and coordination of the PHS Policy ?

Explanation

OLAW, or the Office of Laboratory Animal Welfare, is the government agency responsible for the general administration and coordination of the PHS Policy. The PHS Policy refers to the Public Health Service Policy on Humane Care and Use of Laboratory Animals, which sets guidelines for the ethical treatment of animals used in research funded by the Public Health Service. OLAW ensures that institutions comply with these guidelines and promotes the humane care and use of animals in research. USDA, NIH, and LAW are not specifically responsible for the administration and coordination of the PHS Policy.

Submit
115. According to the PHS Policy, the IACUC must have at least_______ members

Explanation

According to the PHS Policy, the IACUC must have at least 5 members. This ensures that there is a diverse range of perspectives and expertise represented on the committee, allowing for a comprehensive review and evaluation of animal research protocols. With more members, the IACUC can effectively assess the ethical implications and potential risks associated with animal research, ultimately promoting animal welfare and scientific integrity.

Submit
116. How often must the IACUC file a copy of their review of animal care programs with the Director of NIH?

Explanation

The IACUC must file a copy of their review of animal care programs with the Director of NIH at least annually. This means that they are required to submit this report once every year to ensure compliance with animal care regulations and standards.

Submit
117.              One that that rabbits are very susceptible to is ?

Explanation

Rabbits are very susceptible to overheating and can easily suffer from heatstroke. Their thick fur and small size make it difficult for them to regulate their body temperature, especially in hot weather. Heatstroke can be extremely dangerous for rabbits and can lead to severe health issues or even death. Therefore, it is important to ensure that rabbits are kept in a cool and well-ventilated environment to prevent overheating.

Submit
118.          Although _____in monkeys is similar to AIDS in humans____ is not related to HIV and is not infectious to humans

Explanation

The given correct answer is "SAIDS; SRV". The term "SAIDS" is similar to AIDS in humans, but it is not related to HIV and is not infectious to humans. The acronym "SRV" refers to Simian Retrovirus, which is the virus that causes SAIDS in monkeys. This explanation clarifies that SAIDS is a similar condition to AIDS in humans, but it is specific to monkeys and does not pose a risk to human health.

Submit
119.              Guinea pigs should not be housed with animal species such as rabbits, cats, and dogs that many carry_________subclinically becuase guina pigs are susceptible to infection

Explanation

Guinea pigs should not be housed with animal species such as rabbits, cats, and dogs that may carry Bordetella bronchiseptica subclinically because guinea pigs are susceptible to infection.

Submit
120. Which area of the surgical grown is considered the sterile field?

Explanation

The area of the surgical gown that is considered the sterile field is from the shoulders to the waist. This is because this area is most likely to come into contact with the surgical site and needs to be kept free from any contaminants to prevent infection.

Submit
121. Should an emergency occur such as cardiac or respiratory arrest, the first thing to to is ___________

Explanation

In the event of an emergency such as cardiac or respiratory arrest, the first priority should be to establish an open airway. This is crucial in order to ensure that the individual can breathe properly and receive oxygen. By opening the airway, any obstructions or blockages can be cleared, allowing for the passage of air into the lungs. This initial step is essential in providing immediate assistance and increasing the chances of successful resuscitation.

Submit
122.                If working with this species of primates the persons in close contact with them should be instructed to treat all as potentially infectious carriers of Herpes B virus and wear appropriate protective clothing to prevent exposure.

Explanation

The correct answer is macaques. Macaques are a species of primates that can carry the Herpes B virus. Therefore, when working with this species, it is important to treat all macaques as potentially infectious carriers of the virus and take necessary precautions to prevent exposure. Squirrel monkeys and other types of monkeys are not specifically mentioned as carriers of the Herpes B virus in the given information.

Submit
123. The scientific name for the agent that causes "Snuffles" in rabbits is _____________.

Explanation

The scientific name for the agent that causes "Snuffles" in rabbits is Pasteurella multocida. "Snuffles" is a common respiratory disease in rabbits, and Pasteurella multocida is the primary bacterial pathogen responsible for it. This bacterium can cause a range of symptoms, including nasal discharge, sneezing, and difficulty breathing. It is important to diagnose and treat "Snuffles" promptly to prevent the spread of the infection and to ensure the well-being of the rabbits.

Submit
124. The definition of "animal" in the PHS Policy is the same as the one found in the Guide

Explanation

The Guide refers to a vertebrate animal used in research, teaching, and testing, whereas PHS Policy refers to live, vertebrate animal used or intended for use for the same purposes

Submit
125.
  1. Tricaine methane sulfonate solution should be buffered with ____ before use?

Explanation

Tricaine methane sulfonate solution should be buffered with sodium bicarbonate before use. Sodium bicarbonate is a commonly used buffer in biological and pharmaceutical applications. It helps to maintain the pH of the solution, ensuring stability and effectiveness of the Tricaine methane sulfonate. Other options such as sodium, saline, and bicarbonate alone may not provide the necessary buffering capacity required for the solution.

Submit
126. The endotracheal tube is a _____________placed in the _________to facilitate ___________of an animal

Explanation

The endotracheal tube is a flexible, cuffed tube that is placed in the trachea to facilitate assisted ventilation of an animal.

Submit
127. How often should you clean bedded cages ?

Explanation

Bedded cages should be cleaned once a week to maintain cleanliness and hygiene for the animals. Cleaning the cages on a regular basis helps to remove waste, odors, and potential sources of infection. It also ensures that the animals have a clean and comfortable living environment. Cleaning the cages more frequently, such as daily or twice a week, may be excessive and unnecessary, while cleaning them less frequently, such as once every two weeks, may lead to unsanitary conditions for the animals. Therefore, cleaning bedded cages once a week strikes a balance between maintaining cleanliness and minimizing stress for the animals.

Submit
128. HEPA filters are only efficient in removing up to _______________of particulate matter.

Explanation

HEPA filters are highly efficient in removing particulate matter from the air. The given answer of 99.7% suggests that these filters can remove almost all of the particulate matter present in the air, leaving only a very small fraction behind. This high level of efficiency makes HEPA filters a popular choice for air purifiers and HVAC systems in order to improve indoor air quality and reduce the risk of respiratory problems caused by airborne pollutants.

Submit
129. USDA identification tags for dogs and cats must be retained for ___ year(s) for possible review by a USDA inspector

Explanation

USDA identification tags for dogs and cats must be retained for one year for possible review by a USDA inspector. This means that pet owners should keep the tags on their pets for a period of one year in case a USDA inspector wants to examine them. It is important to retain these tags as they serve as proof of compliance with USDA regulations and can be used to ensure the health and safety of the animals.

Submit
130. A health care concept often used in laboratory animal medicicne is __________________management.

Explanation

Herd health is the correct answer because it is a health care concept commonly used in laboratory animal medicine. It refers to the overall health and well-being of a group or population of animals, rather than focusing on individual animals. This concept is important in laboratory animal medicine as it helps to monitor and manage the health of a group of animals, ensuring their welfare and preventing the spread of diseases within the population.

Submit
131. The term "W/W" means ________ 

Explanation

The term "W/W" refers to "Weight in Weight." This term is commonly used in various industries to express the concentration of a substance in a mixture. It indicates the weight of a particular component in relation to the total weight of the mixture. For example, if a solution is described as 10% W/W, it means that 10 grams of the substance are present in every 100 grams of the solution.

Submit
132. The total blood volume in a 218 g rate is approximately ____________.

Explanation

The total blood volume in a rat is approximately 13-17 mls. This is because rats have a blood volume of approximately 60-80 ml/kg, and the average weight of a rat is around 218 g. By calculating the blood volume based on weight, we can estimate that a rat would have a blood volume of approximately 13-17 mls.

Submit
133. How often should you clean automatic waterers, bottles, feeders, and buckets?

Explanation

Automatic waterers, bottles, feeders, and buckets should be cleaned once a week. Regular cleaning is important to prevent the buildup of bacteria, algae, and other contaminants that can affect the quality of the water and feed. Cleaning them once a week ensures that they remain hygienic and safe for the animals to use.

Submit
134. The Guide for the care and use of Agricultural Animals in Agricultural Research and teaching focuses on the humane care of animals used in production agriculture. What type of animals are excluded from this publication ?

Explanation

The Guide for the care and use of Agricultural Animals in Agricultural Research and teaching focuses on the humane care of animals used in production agriculture. This means that it does not cover animals used in biomedical research and teaching, as they have different requirements and considerations. The publication instead focuses on animals used for food and fiber research, as well as equine animals.

Submit
135. Rats tend to become obese if fed ad libitum. What is recommended for rats in long-term studies to prevent obesity?

Explanation

Rats tend to become obese if they are allowed to eat as much as they want (ad libitum). To prevent obesity in rats during long-term studies, it is recommended to provide restricted feeding, meaning that their food intake is limited. This helps control their calorie intake and prevents excessive weight gain. Feeding a low-fat diet or only one to two bites of food a day may not be sufficient to prevent obesity in rats, while doing nothing would not address the issue of potential obesity. Restricted feeding is the most appropriate solution in this context.

Submit
136. Animals species that may require higher temperatures than that recommended for rodents and rabbits would include ________.

Explanation

Animals such as pigeons, chickens, and alligators are likely to require higher temperatures than what is recommended for rodents and rabbits. This could be due to their natural habitat and physiological needs. Pigeons and chickens are birds that typically require warmer environments, while alligators are reptiles that are adapted to warmer climates. These animals may have different temperature requirements for optimal health and functioning compared to rodents and rabbits.

Submit
137. In what order should these species be attended to?

Explanation

The correct order in which these species should be attended to is guinea pig first and then rabbit. This is because each species has its own specific care requirements and attending to the guinea pig first ensures that its needs are met before moving on to the rabbit. Additionally, transitioning from one species to another without proper care and preparation can be stressful for both animals.

Submit
138. Suppose you are asked to change mice in a facility that houses animals of various microbiological status. In which order would you do the rooms ?

Explanation

The correct order to change the rooms in a facility that houses animals of various microbiological status is axenic, gnotobiotic, SPF, conventional, quarantine. This order ensures that the rooms with the highest level of microbiological control, such as axenic and gnotobiotic, are changed first to minimize the risk of contamination. The SPF and conventional rooms are then changed, followed by the quarantine room, which is typically used for newly arrived animals that may carry pathogens. This sequence helps maintain the integrity of the facility and minimize the spread of infectious agents.

Submit
139. It is recommended that the surface of each of the arms should receive__________strokes while scrubbing prior to surgery

Explanation

The recommended number of strokes for scrubbing the surface of each arm prior to surgery is 10. This suggests that a thorough scrubbing is necessary to ensure cleanliness and reduce the risk of infection during the surgical procedure.

Submit
140.                 Ferrets are more common as pets then in research however they are used in these type of studies and replace these   animals in research?

Explanation

Ferrets are commonly kept as pets, but they are also used in certain types of research studies. They are specifically used to screen compounds for their potential to cause emesis (vomiting), for neonatal intubation practice, and for drug studies. In these research areas, ferrets are used as replacements for dogs and cats.

Submit
141. Toxicology is the study of ____________

Explanation

Toxicology is the scientific discipline or study of poisons, including their effects and detection. It examines the adverse effects of chemical, physical, or biological agents on living organisms, and it focuses on understanding the nature of these harmful substances and their impact on health.

Submit
142.               This deficiencies cause rickets in NW monkeys and young animals ?

Explanation

Vitamin D deficiency can cause rickets in NW monkeys and young animals. Rickets is a condition that affects the development of bones and teeth, leading to weak and soft bones. Vitamin D is essential for the absorption of calcium and phosphorus, which are important for bone health. Without enough vitamin D, the body cannot properly use these minerals, resulting in the development of rickets.

Submit
143. To reonstitute a 1g vial of freeze-dried (lyophilized) drug to yield a 5% solution you would add what volume of diluent ?

Explanation

To reconstitute a 1g vial of freeze-dried drug to yield a 5% solution, you would add 20ml of diluent. This means that for every 1g of the drug, 20ml of diluent is needed to achieve a 5% concentration. Adding more or less diluent would result in a different concentration of the solution.

Submit
144.    This virus is the most likely pathogen to cause clinical respiratory disease in adult immunocompetent mice?

Explanation

Sendai Virus is the most likely pathogen to cause clinical respiratory disease in adult immunocompetent mice. This virus is known for causing respiratory infections in mice, particularly in adult mice with a healthy immune system. It is a common pathogen used in research studies to induce respiratory disease in mice for experimental purposes. MHV, Dehydration, and Rickettsia are not typically associated with causing respiratory disease in adult immunocompetent mice.

Submit
145.
  1. Cervical dislocation can be used for immature rats weighing less than ___ g and rabbits weighting less than ___kg.

Explanation

Cervical dislocation can be used for immature rats weighing less than 200g and rabbits weighing less than 1kg.

Submit
146.      What is the gestation period for a Gerbil?  

Explanation

The correct answer is 24-26 days. Gerbils have a relatively short gestation period compared to other animals. This means that the time it takes for a gerbil to develop and be born is typically around 24-26 days. This is a relatively short amount of time compared to other small mammals, such as mice or rats, which have longer gestation periods.

Submit
147. Immunological tolerance can be induced _____________

Explanation

Immunological tolerance can be induced more easily if the animal is tolerant to foreign proteins already. This is because tolerance to foreign proteins indicates that the immune system has already recognized and accepted these proteins as "self" rather than "foreign." As a result, the immune system is less likely to mount an immune response against these proteins, making it easier to induce immunological tolerance.

Submit
148. Three popular animal species used for polycloncal antibody production and for use in diagnostic test are _____________.

Explanation

Three popular animal species commonly used for polyclonal antibody production and diagnostic tests are rabbits, goats, and sheep. These animals are chosen for their ability to produce large quantities of antibodies that can be harvested and used for various purposes. Rabbits are often preferred due to their size and ease of handling, while goats and sheep are chosen for their ability to produce high-quality antibodies. Each of these species has its advantages and suitability for different applications in the field of antibody production and diagnostic testing.

Submit
149.  Minimum of ____ hours is required for rodents to recover from the stress of shipment.

Explanation

The question asks for the minimum number of hours required for rodents to recover from the stress of shipment. However, none of the given options provide a specific number of hours. Therefore, the correct answer is "none of the above" as there is no option that accurately represents the minimum recovery time for rodents after shipment stress.

Submit
150.                    2-Phenoxyethanol  is used to euthanasia what species?

Explanation

2-Phenoxyethanol is used to euthanize fish. This substance is commonly used in aquatic environments to euthanize fish in a humane and effective manner. It acts as a sedative and anesthetic, causing the fish to become unconscious and eventually leading to their death. This method is often preferred in fish euthanasia due to its ease of use and minimal stress caused to the fish.

Submit
151. In the US, all research programs must adhere to the PHS Policy

Explanation

The statement is false because not all research programs in the US are required to adhere to the PHS Policy. While many research programs do follow the PHS Policy, there are also other regulations and policies that research programs may need to adhere to depending on the specific field or funding source. Therefore, it is incorrect to say that all research programs in the US must adhere to the PHS Policy.

Submit
152. How often should you clean wire bottom cages ?

Explanation

Wire bottom cages should be cleaned once every two weeks. This is because wire bottom cages allow waste to fall through the wire and accumulate in a tray underneath. Cleaning the cage once every two weeks ensures that the waste does not build up too much, maintaining a clean and hygienic living environment for the animal. Cleaning more frequently, such as daily or twice a week, may not be necessary and could cause unnecessary stress to the animal.

Submit
153.              Which of these is not a chapter  in the Guide ?

Explanation

The correct answer is "Euthanasia of lab animals" because the question asks for a chapter that is not included in the Guide. The other options, such as "Physical plant," "Veterinary care," and "Animal care and Use program," are all potential chapters that could be included in the Guide. However, "Euthanasia of lab animals" is not mentioned as a chapter, indicating that it is not included in the Guide.

Submit
154.           Cervical lymphadenitis characterized by abscessation of the cervical lymph nodes is commonly in

Explanation

Cervical lymphadenitis, which is the inflammation and abscess formation in the cervical lymph nodes, is a common condition in guinea pigs. This means that guinea pigs often experience this specific type of infection in their neck lymph nodes. The other options, rabbits, gerbils, and nonhuman primates, do not have a known high prevalence of cervical lymphadenitis. Therefore, guinea pigs are the most likely answer based on the information provided.

Submit
155. Which guideline is most effective in improving biosecurity for laboratory animal programs?

Explanation

This guideline is the most effective in improving biosecurity for laboratory animal programs, as it prevents the introduction of animals with unknown health statuses or potential pathogens into the facility. By restricting employees from obtaining animals from unknown sources, the program can better ensure the health and safety of the laboratory animals and maintain the integrity of research studies.

Submit
View My Results

Quiz Review Timeline (Updated): Jul 2, 2025 +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Jul 02, 2025
    Quiz Edited by
    ProProfs Editorial Team
  • Mar 31, 2012
    Quiz Created by
    ADastgir
Cancel
  • All
    All (155)
  • Unanswered
    Unanswered ()
  • Answered
    Answered ()
Mice that have had DNA from a different animal inserted into thier...
What does GLP stand for?
What is the term used to describes the act of inducing humane death in...
SOPs must be in place for the housing, feeding, handling, and care of...
Which of the following will prevent cross-contamination within a...
In the case  of animals traumatized due to fighting animal care...
             ...
Thoracic compression is the preferred euthanasia method for birds
     Direct immersion of an animal into formalin...
The  IACUC ___________
Identify the route of injection that provides the fatest abosrbtion...
     This species of rodent should be provided...
When animals touch one another and transmit disease they are said to...
      What are the 3R's ?
                   ...
The animal census is a ________
    What is the most common breed of rabbit used in...
     If a rabbits hindquarters are not supported...
All mammals have a_____ chambered heart
What does the acronym PHS stand for?
            ...
Which of the following are methods of setrilization ?
Of the following solutions, ___________are usually reserved for use on...
              ...
The IACUC must conduct inspections of the animals facilities and...
    Helicobacter spp. are motile bacteria that inhabit...
       Unlike mice that will mate with...
      The best place to take blood collection...
Some of the extra requirments of immunocompromised animals are...
Platelets are essential for _______
Sexual reproduction is conrolled by __________.
Tricaine methane sulfonate (TMS, MS 222)  is used to euthanasia...
The primary ganting agency through which the untied states conducts...
Dystocia is a condition which may be encountered ___________
The gauge of the needle refers to the ________
Samples of all tissues collected during a necropsy are prserved...
Painful Procedures can be performed on unanesthetized animals as long...
What is the only acceptable methods of euthanasia listed for nonhuman...
Per diem cost are the expense required to maintain one animal for...
The most desirable site for an IM injection is _________
Identify the zoonotic disease most accociated with cats.
A cage card is considered raw data when you measure the animal's body...
            For...
When disease transmitted through the air (airbone or aerosol...
When performing the initial scrub of the surgical area ___________is...
If animals are to be euthanized at the end of the study, the method of...
A condition in rodents caused by high temperaturs and low relative...
              ...
      More than any other laboratory animal...
Respiration ____________.
   Which of these is an inbred rat strains ?
             ...
When giving an intramuscular injection in the hind limb, care must be...
Which part of the mouse model BALB/c StCrl p GF (F83) is the strain...
Consult with a veterinarian who has the appropriate _____, and ____...
The integumentary system is comprised of _______
Oxygen and carbon dioxide are exchanged between the blood and the air...
How often should you clean dog and other large animals cages or stalls...
Research institutions provide The Public Health Service with a signed...
                 ...
       Sneezing and the presence of a...
What does the acronym TPR stand for ?
The condition where no living thing organisms are present on a surface...
           Guinea...
If a 4% drug solution were to be administered at a dose rate of 1 ml...
What agency is responsible for determining whether new medical devices...
A rabbit has a total blood volume percentage of 6%. What would be the...
            ...
A typical NIH grant provides money for a ________ year period
  ...
           ...
Which of the following responsibilities is NOT typically associated...
The receptive stance (fixed position with hindquarters elevated and...
The PHS Policy includes the Health Research Extension Act of 1985 and...
Unplanned changes to a procedure during the conduct of a study are...
Thoracic compression is the preferred euthanasia method for birds
An endotracheal tube is used to ___________
          ...
According to the Health Research Extension Act of 1985, the IACUC must...
The lymphatic system _________________
          The most common...
   Microwave irradiation requires a special irradiator
The total blood volume in an animal's body equals approximately...
  Cedar is not recommended bedding material for gerbils because...
                    ...
A purple top tube contains which anticoagulant?
The PHS Policy requires that all assurance records related directly to...
Which of these carry salmonella ?
AAALAC International __________________. (identify the false...
                  ...
If it costs $6000.00 per year to maintian 200 rats, what should the...
Which of the following lab animal spcies does not prodice a good model...
The addition of a male to a cage which has held only females,...
There is another form of the Guide just for Farm animals used in...
The left ventricle contracts, pumping blood to _______
In goats, cattle, and sheep the breakdown of cellulose occurs...
Tissue samples collected during necropsy should be...
Which agency enforces the Toxic Substances Control Act (TSCA) relating...
 Fish have low tolerance for CO2, so it is a rapid method of...
Besides dogs and cats, which other animal must be vaccinated for...
Nude mice lack a _____________
Of four stages of estrus which is defined as that where follicle...
                      ...
An inanimate object that provides a mechanical means of disease...
            How...
The most information about temperature in a secondary enclsoure of...
       The most common cause of disease...
     This species of rodent is more solitary than...
          Of the two...
An institution where each department keeps and uses animals in its own...
                          ...
The recommended temperature ranges for secondary enclosures for most...
     When chinchillas are handled roughly become...
What government agency is responsible for the general administration...
According to the PHS Policy, the IACUC must have at least_______...
How often must the IACUC file a copy of their review of animal care...
            ...
         Although _____in...
            ...
Which area of the surgical grown is considered the sterile field?
Should an emergency occur such as cardiac or respiratory arrest, the...
              ...
The scientific name for the agent that causes "Snuffles" in...
The definition of "animal" in the PHS Policy is the same as the one...
Tricaine methane sulfonate solution should be buffered with ____...
The endotracheal tube is a _____________placed in the _________to...
How often should you clean bedded cages ?
HEPA filters are only efficient in removing up to _______________of...
USDA identification tags for dogs and cats must be retained for ___...
A health care concept often used in laboratory animal medicicne is...
The term "W/W" means ________ 
The total blood volume in a 218 g rate is approximately ____________.
How often should you clean automatic waterers, bottles, feeders, and...
The Guide for the care and use of Agricultural Animals in Agricultural...
Rats tend to become obese if fed ad libitum. What is recommended for...
Animals species that may require higher temperatures than that...
In what order should these species be attended to?
Suppose you are asked to change mice in a facility that houses animals...
It is recommended that the surface of each of the arms should...
               ...
Toxicology is the study of ____________
             ...
To reonstitute a 1g vial of freeze-dried (lyophilized) drug to yield a...
   This virus is the most likely pathogen to cause clinical...
Cervical dislocation can be used for immature rats weighing less than...
     What is the gestation period for a Gerbil?...
Immunological tolerance can be induced _____________
Three popular animal species used for polycloncal antibody production...
 Minimum of ____ hours is required for rodents to recover from...
                  ...
In the US, all research programs must adhere to the PHS Policy
How often should you clean wire bottom cages ?
            ...
          Cervical...
Which guideline is most effective in improving biosecurity for...
Alert!

Advertisement