Infectious Viruses Diseases Quiz

23 Questions | By MaddieShirley | Updated: Mar 20, 2022 | Attempts: 1956

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Based on chapter 8 of Robbins and Cotran pathologic Basis of Disease, 7th edition.

Questions and Answers

1.
Viruses are classified by
1. Their nucleic acid genome (DNA or RNA) (Double stranded or single stranded)
2. The shape of the capsid (icosahedral or ______)
3. The presence or absence of a ______ envelope
4. Their mode of replication
5. The preferred cell type for replication ( ie tissue _______)
6. The type of pathology
- A.
  
  Helical, lipid, tropism
- B.
  
  Spherical, bilayer, prostatism
- C.
  
  Spherical, protein, pleomorphism
2.
- (Viruses are only 20-300 nm in size and so are best visualised with the electron microscope. However, some viral particles aggregate within the cells they infect and form characteristic inclusion bodies.)
- Ebstein Barr virus infected cells have large eosinophilic cytoplasmic inclusions.
- A.
  
  True
- B.
  
  False
3.

Where does herpes zoster virus reside during latency?
- A.
  
  Langerhan cells
- B.
  
  Dorsal root ganglia
- C.
  
  Ventral root ganglia
- D.
  
  Lateral horn of spinal cord
- E.
  
  Pons
- F.
  
  Hypothalamus
4.

Bacterial cells are _ _ _ _ _ _ _ _ _ _ s, meaning that they have a cell membrane but lack membrane bound nuclei and other membrane bound organelles
5.

Which of the following are obligate intracellular organisms? (4)
- A.
  
  Chlamydia
- B.
  
  Neisseria
- C.
  
  Rickettsiae
- D.
  
  HIV
- E.
  
  Mycoplasma
- F.
  
  Clostridium
6.

Mycoplasma is a gram negative bacteria because it has a cell wall that does not retain crystal violet stain.
- A.
  
  True
- B.
  
  False
7.

Chlamydia trachomatis is the most common cause of female infertility.
- A.
  
  True
- B.
  
  False
8.

How is Mycoplasma pneumonia transmitted?
- A.
  
  Blood-borne
- B.
  
  Aerosol
- C.
  
  Faecal-oral
- D.
  
  Sexually transmitted
- E.
  
  Insect vector
- F.
  
  Animal contact
- G.
  
  Contaminated water
- H.
  
  Contaminated food
9.

Thermal dimorphic fungi grow as hyphal forms at room temperature but as yeasts at body temperature.
- A.
  
  True
- B.
  
  False
10.

Which of the following have eukaryotic cell/s? (5)
- A.
  
  Fungi
- B.
  
  Bacteria
- C.
  
  Protazoa
- D.
  
  Viruses
- E.
  
  Prions
- F.
  
  Algae
- G.
  
  Helminths
- H.
  
  Humans
11.

How is Toxoplasma gondii transmitted? (2)
- A.
  
  Blood-borne
- B.
  
  Aerosol
- C.
  
  Faecal-oral
- D.
  
  Sexually
- E.
  
  Insect vector
- F.
  
  Animal contact
- G.
  
  Contaminated water
- H.
  
  Contaminated food
12.

Most ingested enveloped viruses are killed by bile and digestive enzymes, but non-enveloped viruses may be resistant.
- A.
  
  True
- B.
  
  False
13.
Which of the following enteropathogenic bacteria causes symptoms by:
- multiplying inside the mucous layer overlying the gut epithelium and releasing exotoxins that cause the gut epithelium to secrete high volumes of watery diarrhoea? (2)
- A.
  
  Campylobacter jujeni
- B.
  
  Vibrio cholerae
- C.
  
  Shigella species
- D.
  
  Salmonella species
- E.
  
  Toxigenic Escherichia coli
- F.
  
  Serratia marcescens
14.
Which of the following enteropathogenic bacteria causes symptoms by:
- invading and damaging the intestinal mucosa and lamina propria, causing ulceration, inflammation and haemorrhage, clinically manifesting as dysentry? (3)
- A.
  
  Campylobacter jujeni
- B.
  
  Vibrio cholerae
- C.
  
  Shigella species
- D.
  
  Salmonella species
- E.
  
  Toxigenic Escherichia coli
- F.
  
  Serratia marcescens
15.

Why does a viral resipratory infection predispose to a secondary bacterial respiratory infection? (This question is not graded)
16.

The vagina is protected from pathogens by a ____ pH resulting from catabolism of _______ in the normal epithelium by ________.
- A.
  
  High, phospholipids, lactobacilli
- B.
  
  Low, phospholipids, lactococci
- C.
  
  High, glycogen, lactococci
- D.
  
  Low, glycogen, lactobacilli
17.

Rubella infection during which trimester is most dangerous for the fetus?
- A.
  
  First
- B.
  
  Second
- C.
  
  Third
18.

CMV, HBV and HTLV-1 can all be transmitted to a baby via breastmilk.
- A.
  
  True
- B.
  
  False
19.

Low IgG avidity antibody marker of recent infection. High IgG avidity antibody marker of past infection.
- A.
  
  True
- B.
  
  False
20.

Exotoxins are proteins secreted by bacteria that cause cellular injury and disease. Which of the following type of exotoxin is secreted by Clostridium tetani and Clostridium botulinum?
- A.
  
  Enzyme
- B.
  
  A-B toxin
- C.
  
  Neurotoxin
- D.
  
  Superantigen
21.

Exotoxins are proteins secreted by bacteria that cause cellular injury and disease. Which of the following type of exotoxin is secreted by Bacillus anthracis, Vibrio cholerae and some strains of Escherichia coli?
- A.
  
  Enzyme
- B.
  
  A-B toxin
- C.
  
  Neurotoxin
- D.
  
  Superantigen
22.

Exotoxins are proteins secreted by bacteria that cause cellular injury and disease. Which of the following types of exotoxin can be secreted by Staphylococcus aureus? (2)
- A.
  
  Enzyme
- B.
  
  A-B toxin
- C.
  
  Neurotoxin
- D.
  
  Superantigen
23.

Following infection with ______ streptococci, antibodies can cross react with cardiac proteins and become deposited in the heart leading to _______, and/or antistreptococcal antibody/streptococcal antigen complexes can form and be deposited in the renal glomeruli causing post streptococcal _______.
- A.
  
  α haemolytic, rheumatic fever, glomerulosclerosis
- B.
  
  α haemolytic, infective endocarditits, glomerulonephritis
- C.
  
  β haemolytic, rheumatic fever, glomerulonehpritis
- D.
  
  β haemolytic, infective endocarditis, glomerulosclerosis