Immunology - Complement Pathway (6)

6 Questions

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Immunology Quizzes & Trivia

Questions and Answers
  • 1. 
    Regarding the complement pathway, which one of the following is the most accurate?
    • A. 

       C3 convertase protects normal cells from lysis by complement.

    • B. 

      C3a is a decay-accelerating factor and causes the rapid decay and death of bacteria.

    • C. 

      In general, gram-positive bacteria are more likely to be killed by complement than gram-negative bacteria.

    • D. 

      The membrane attack complex is formed as a result of activation of the classic pathway but not by activation of the alternative pathway.

    • E. 

       The first time a person is exposed to a microorganism, the alternative pathway of complement is more likely to be activated than the classic pathway.

  • 2. 
    Of the following complement components, which one is the most important opsonin?
    • A. 

      C1

    • B. 

      C3a

    • C. 

      C3b

    • D. 

      C5a

    • E. 

      C5b

  • 3. 
    Of the following complement components, which one is the most potent in attracting neutrophils to the site of infection (i.e., acting as a chemokine)?
    • A. 

      C1

    • B. 

       C2

    • C. 

      C3b

    • D. 

      C5a

    • E. 

      Mannan-binding lectin

  • 4. 
    Of the following, which one is the most important function of the complex formed by complement components C5b,6,7,8,9?
    • A. 

      To enhance antibody production

    • B. 

      To inhibit immune complex formation

    • C. 

      To opsonize viruses

    • D. 

      To perforate bacterial cell membranes

    • E. 

      To release histamine from mast cells

  • 5. 
    A deficiency of which one of the following complement components predisposes to bacteremia caused by members of the genus Neisseria?
    • A. 

      C1

    • B. 

      C3b

    • C. 

      C5a

    • D. 

       C5b

    • E. 

      C5b,6,7,8,9

  • 6. 
    • A. 

      She has too little C1 inhibitor.

    • B. 

      She has too little C3b.

    • C. 

      She has too little factor B.

    • D. 

       She has too much C5a.

    • E. 

      She has too much C9.