Complement System MCQ Quiz

10 Questions | By Medicinemcq | Last updated: Jul 1, 2022 | Total Attempts: 5608

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Have you studied immunology? Do you think you can easily pass this 'Complement system MCQ quiz' that we have brought specially for you? The quiz is based on the complement system, and through this quiz, we will be testing your knowledge of the same. Not only is the quiz good for you to test yourself, but it will also help you to learn more. Let's go for it. Best of luck to you!

Questions and Answers

1.

Regarding the complement pathway, which one of the following is the most accurate?
- A.
  
  C3 convertase protects normal cells from lysis by complement.
- B.
  
  C3a is a decay-accelerating factor and causes the rapid decay and death of bacteria.
- C.
  
  In general, gram-positive bacteria are more likely to be killed by complement than gram-negative bacteria.
- D.
  
  The membrane attack complex is formed as a result of activation of the classic pathway but not by activation of the alternative pathway.
- E.
  
  The first time a person is exposed to a microorganism, the alternative pathway of complement is more likely to be activated than the classic pathway.
2.

Of the following complement components, which one is the most important opsonin?
- A.
  
  C1
- B.
  
  C3a
- C.
  
  C3b
- D.
  
  C5a
- E.
  
  C5b
3.

Of the following complement components, which one is the most potent in attracting neutrophils to the site of infection (i.e., acting as a chemokine)?
- A.
  
  C1
- B.
  
  C2
- C.
  
  C3b
- D.
  
  C5a
- E.
  
  Mannan-binding lectin
4.

Of the following, which one is the most important function of the complex formed by complement components C5b,6,7,8,9?
- A.
  
  To enhance antibody production.
- B.
  
  To inhibit immune complex formation.
- C.
  
  To opsonize viruses
- D.
  
  To perforate bacterial cell membranes.
- E.
  
  To release histamine from mast cells.
5.

A deficiency of which one of the following complement components predisposes to bacteremia caused by members of the genus Neisseria?
- A.
  
  C1
- B.
  
  C3b
- C.
  
  C5a
- D.
  
  C5b
- E.
  
  C5b,6,7,8,9
6.

Your patient is a 20-year-old woman who complains of swellings on her arms and legs and a feeling of fullness in her throat that makes it difficult to breathe. The swellings are not red, hot, or tender. You suspect she may have angioedema caused by a complement abnormality. Of the following, which one is the most likely explanation?
- A.
  
  She has too little C1 inhibitor.
- B.
  
  She has too little C3b.
- C.
  
  She has too little factor B.
- D.
  
  She has too much C5a.
- E.
  
  She has too much C9.
7.

What are several of the complement components?
- A.
  
  Enzymes
- B.
  
  Antibodies
- C.
  
  Hormones
- D.
  
  None of these
8.

What is the initial complement component, bound by complement-fixing antibodies?
- A.
  
  C1s
- B.
  
  C3b
- C.
  
  C1q
- D.
  
  None of these
9.

What complement component is C3 cleaved by?
- A.
  
  Factor B
- B.
  
  C3bBb
- C.
  
  Factor D
- D.
  
  None of these
10.

What does the membrane attack complex in the complement pathway consist of?
- A.
  
  Colicins
- B.
  
  C3b3b,Bb
- C.
  
  OH.
- D.
  
  C5b,6,7,8,9