Immunology #5 - T Cell

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| By Kmccor2008
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Kmccor2008
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Quizzes Created: 7 | Total Attempts: 3,546
| Attempts: 349
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  • 1/7 Questions

    Class II MHC molecules are associated with which cells?

    • Dendritic cells
    • Macrophages
    • B cells
    • All of the above
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About This Quiz

Explore the complexities of T cell receptors in this Immunology #5 quiz. Topics include binding site count, alpha chain characteristics, proteins linked to SCID, CD8 traits, and MHC expression. Ideal for students and professionals enhancing their understanding of immunological functions.

Immunology Quizzes & Trivia

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  • 2. 

    MHC I is expressed in virtually all nucleated cells of the body

    • True

    • False

    Correct Answer
    A. True
    Explanation
    MHC I, or Major Histocompatibility Complex class I, is a protein that is present on the surface of almost all nucleated cells in the body. It plays a crucial role in the immune system by presenting antigens to cytotoxic T cells, which helps in identifying and eliminating infected or abnormal cells. Therefore, it is correct to say that MHC I is expressed in virtually all nucleated cells of the body.

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  • 3. 

    Which of the following does NOT characteristic of CD8?

    • Intracellular

    • MHC I

    • Helper

    • Mostly viral infections

    Correct Answer
    A. Helper
    Explanation
    The correct answer is "Helper." CD8 is a type of T-cell that is involved in cell-mediated immunity and recognizes antigens presented on MHC class I molecules. CD8 T-cells are not considered "helper" cells, as helper T-cells are typically CD4-positive and assist in the activation of other immune cells. CD8 T-cells are primarily involved in killing infected cells and are important in the defense against viral infections.

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  • 4. 

    Severe combined immunodeficiency Syndrome (SCID) is due to a lack of function of which protein?

    • MHC I

    • MHC II

    • RAG

    • DNA polymerase

    Correct Answer
    A. RAG
    Explanation
    RAG (recombination activating gene) is responsible for the rearrangement of genes that encode the antigen receptors on immune cells. In severe combined immunodeficiency syndrome (SCID), there is a lack of function of RAG protein, which leads to an inability to produce functional immune cells. This results in a severe impairment of the immune system, making individuals highly susceptible to infections.

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  • 5. 

    How many binding sites are present on a T cell receptor?

    • 1

    • 2

    • 3

    • 4

    Correct Answer
    A. 1
    Explanation
    A T cell receptor typically has one binding site. This binding site allows the T cell receptor to recognize and bind to specific antigens presented by antigen-presenting cells. The binding of the T cell receptor to the antigen triggers a series of signaling events that activate the T cell, leading to an immune response against the antigen. Therefore, the correct answer is 1.

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  • 6. 

    Which is repsonsible for the variations of MHC polymorphisms within different geographical areas?

    • Differential selection

    • Balancing selection

    • Homozygous selection

    • Directional selection

    Correct Answer
    A. Directional selection
    Explanation
    Directional selection is responsible for the variations of MHC polymorphisms within different geographical areas. Directional selection occurs when a particular phenotype is favored over others, leading to a shift in the frequency of alleles in a population. In the case of MHC polymorphisms, directional selection may be driven by factors such as exposure to different pathogens or the need to adapt to specific environmental conditions. This selection pressure can result in the maintenance of multiple MHC alleles within a population, allowing for a diverse range of immune responses to combat various pathogens.

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  • 7. 

    Which of these apply to the alpha chain of T cell receptors? (select all that apply)

    • V

    • D

    • J

    • C

    Correct Answer(s)
    A. V
    A. J
    A. C
    Explanation
    The alpha chain of T cell receptors contains the V (variable), J (joining), and C (constant) regions. These regions are responsible for the diversity and specificity of T cell receptors, allowing them to recognize and bind to specific antigens. The V region is responsible for antigen recognition, while the J and C regions are involved in signal transduction and cell activation. Therefore, the correct answer is V, J, C.

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  • Current Version
  • Mar 21, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Sep 29, 2012
    Quiz Created by
    Kmccor2008
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