HIV/AIDS & Tumor Immunology

15 Questions | By Esidra | Last updated: Mar 21, 2022 | Total Attempts: 302

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1.

Which HIV cell surface protein is responsible for binding a helper T cell?
- A.
  
  Gp41
- B.
  
  Reverse transcriptase
- C.
  
  Gp120
- D.
  
  Proviral DNA
2.

Select the correct order of the HIV infection process of a Helper T cell.
- A.
  
  Binding of gp41 --> Proviral DNA--> Genomic viral DNA --> Synthesis of new Viral proteins --> Integration of provirus DNA
- B.
  
  Binding of gp120--> Genomic viral DNA --> reverse transcription into Proviral DNA -->Integration of Provirus DNA -->Synthesis of new viral proteins
- C.
  
  Binding of gp120 --> Proviral DNA --> reverse transcription into Genomic DNA --> Integration into host DNA --> Synthesis of new HIV proteins
- D.
  
  Binding of gp41 --> Genomic DNA --> Integration into host DNA --> Reverse transcription into proviral DNA --> Synthesis of new HIV proteins.
3.

In a person with AIDS, which type of cell is mainly being attacked/depleted? (Select 2)
- A.
  
  CD4+ T
- B.
  
  CD8+ T
- C.
  
  Helper T Cell
- D.
  
  Natural Killer Cells
4.

Someone infected with HIV may be asymptomatic for years
- A.
  
  True
- B.
  
  False
5.

AIDS is diagnosed when
- A.
  
  A person has become infected by the HIV virus
- B.
  
  Antibodies to the proteins encoded by gag, pol, and env are found in the blood
- C.
  
  Chronic fever, weight loss, and diarrhea are present with the virus
- D.
  
  A person is infected with the HIV Virus and has been infected by opportunistic infections
6.

The most common AIDS diagnostic test is one that isolates the virus from a blood sample.
- A.
  
  True
- B.
  
  False
7.

Which of the following AIDS diagnostic tests use electrophoresis and detects up to 9 HIV viral proteins?
- A.
  
  ELISA
- B.
  
  Western Blot
- C.
  
  PCR
- D.
  
  IFA
8.

Which test should be used as a starting point in the diagnosis of AIDS?
- A.
  
  ELISA
- B.
  
  Western Blot
- C.
  
  IFA
- D.
  
  PCR
9.

Which of the following is a reason to HIV's resistance to drugs?
- A.
  
  HIV has a high mutation rate due to reverse transcriptase errors
- B.
  
  It uses reverse transcriptase
- C.
  
  It isn't very resistant to drugs
- D.
  
  Most drugs are protease inhibitors, which treat symptoms and not the viral infection
10.

An absolute CD4+T cell count of 150 in a cubic millimeter of blood would indicate
- A.
  
  The person is an antibody-positive asymptomatic carrier
- B.
  
  The patient is vulnerable to an opportunistic infection
- C.
  
  The patient is in category 1 of the CD4+T categories.
- D.
  
  The patient is not at risk for AIDS
11.

An opportunistic infection that occurs in the eye is the ________
- A.
  
  Human papilloma virus
- B.
  
  Hepatitis C virus
- C.
  
  MAC
- D.
  
  Cytomegalovirus
12.

Which of the following is incorrect regarding CMV retinitis?
- A.
  
  If untreated, the disease can cause blindness within 4 weeks
- B.
  
  It is a member of the herpes virus family
- C.
  
  Treatment is a one time regiment lasting 6 months
- D.
  
  The CMV virus, if untreated, will cause blindness to both eyes
13.

Which of the following are oncofetal genes? (Select 2)
- A.
  
  CEA
- B.
  
  AFP
- C.
  
  RAS
- D.
  
  P53
14.

The membrane attack complex (MAC) is involved in the destruction of tumor cells.
- A.
  
  True
- B.
  
  False
15.

Which of the following would aid in tumor escape?
- A.
  
  Increased immune surveillance
- B.
  
  Tumor decreasing production of immunosuppressive cytokines
- C.
  
  Reduced levels of MHC-1 molecule on the tumor
- D.
  
  Increased levels of Tumor associated and tumor specific antigens