HIV/AIDS & Tumor Immunology

15 Questions | Total Attempts: 174

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Immune System Quizzes & Trivia

Questions and Answers
  • 1. 
    Which HIV cell surface protein is responsible for binding a helper T cell?
    • A. 

      Gp41

    • B. 

      Reverse transcriptase

    • C. 

      Gp120

    • D. 

      Proviral DNA

  • 2. 
    Select the correct order of the HIV infection process of a Helper T cell.
    • A. 

      Binding of gp41 --> Proviral DNA--> Genomic viral DNA --> Synthesis of new Viral proteins --> Integration of provirus DNA

    • B. 

      Binding of gp120--> Genomic viral DNA --> reverse transcription into Proviral DNA -->Integration of Provirus DNA -->Synthesis of new viral proteins

    • C. 

      Binding of gp120 --> Proviral DNA --> reverse transcription into Genomic DNA --> Integration into host DNA --> Synthesis of new HIV proteins

    • D. 

      Binding of gp41 --> Genomic DNA --> Integration into host DNA --> Reverse transcription into proviral DNA --> Synthesis of new HIV proteins.

  • 3. 
    In a person with AIDS, which type of cell is mainly being attacked/depleted? (Select 2)
    • A. 

      CD4+ T

    • B. 

      CD8+ T

    • C. 

      Helper T Cell

    • D. 

      Natural Killer Cells

  • 4. 
    Someone infected with HIV may be asymptomatic for years
    • A. 

      True

    • B. 

      False

  • 5. 
    AIDS is diagnosed when
    • A. 

      A person has become infected by the HIV virus

    • B. 

      Antibodies to the proteins encoded by gag, pol, and env are found in the blood

    • C. 

      Chronic fever, weight loss, and diarrhea are present with the virus

    • D. 

      A person is infected with the HIV Virus and has been infected by opportunistic infections

  • 6. 
    The most common AIDS diagnostic test is one that isolates the virus from a blood sample.
    • A. 

      True

    • B. 

      False

  • 7. 
    Which of the following AIDS diagnostic tests use electrophoresis and detects up to 9 HIV viral proteins?
    • A. 

      ELISA

    • B. 

      Western Blot

    • C. 

      PCR

    • D. 

      IFA

  • 8. 
    Which test should be used as a starting point in the diagnosis of AIDS?
    • A. 

      ELISA

    • B. 

      Western Blot

    • C. 

      IFA

    • D. 

      PCR

  • 9. 
    Which of the following is a reason to HIV's resistance to drugs?
    • A. 

      HIV has a high mutation rate due to reverse transcriptase errors

    • B. 

      It uses reverse transcriptase

    • C. 

      It isn't very resistant to drugs

    • D. 

      Most drugs are protease inhibitors, which treat symptoms and not the viral infection

  • 10. 
    An absolute CD4+T cell count of 150 in a cubic millimeter of blood would indicate
    • A. 

      The person is an antibody-positive asymptomatic carrier

    • B. 

      The patient is vulnerable to an opportunistic infection

    • C. 

      The patient is in category 1 of the CD4+T categories.

    • D. 

      The patient is not at risk for AIDS

  • 11. 
    An opportunistic infection that occurs in the eye is the ________   
    • A. 

      Human papilloma virus

    • B. 

      Hepatitis C virus

    • C. 

      MAC

    • D. 

      Cytomegalovirus

  • 12. 
    Which of the following is incorrect regarding CMV retinitis?
    • A. 

      If untreated, the disease can cause blindness within 4 weeks

    • B. 

      It is a member of the herpes virus family

    • C. 

      Treatment is a one time regiment lasting 6 months

    • D. 

      The CMV virus, if untreated, will cause blindness to both eyes

  • 13. 
    Which of the following are oncofetal genes? (Select 2)
    • A. 

      CEA

    • B. 

      AFP

    • C. 

      RAS

    • D. 

      P53

  • 14. 
    The membrane attack complex (MAC) is involved in the destruction of tumor cells. 
    • A. 

      True

    • B. 

      False

  • 15. 
    Which of the following would aid in tumor escape?
    • A. 

      Increased immune surveillance

    • B. 

      Tumor decreasing production of immunosuppressive cytokines

    • C. 

      Reduced levels of MHC-1 molecule on the tumor

    • D. 

      Increased levels of Tumor associated and tumor specific antigens