Heart Failure And Acute Mi Drugs
Pharm Exam 3
- 1.Your pt is on Enalapril and is complaining of a dry cough. She states that she would prefer not to take this medication anymore. What is an appropriate substitute?
- A.
Spironolactone
- B.
Metoprolol
- C.
Aspirin
- D.
Losartan
- 2.ACE inhibitors are protective to the heart in all of the following ways, EXCEPT:
- A.
Decrease vascular resistance
- B.
Decrease venous tone
- C.
Increase Na retention
- D.
Decrease BP
- 3.What are the two Beta Blockers approved for treatment of heart failure?
- 4.Beta blockers improve heart's function by:
- A.
Inhibiting renin release
- B.
Decreasing heart rate
- C.
Blocking deleterious effects of NE on cardiac muscle fibers
- D.
All of the above
- 5.Diuretics help in heart failure by: (check all that apply)
- A.
Decrease preload
- B.
Decrease cardiac workload
- C.
Increase preload
- D.
Increase after load
- E.
Decrease O2 demand
- 6.What is the most commonly used diuretic in HF?
- 7.What HF medication can help relieve pulmonary congestion and peripheral edema?
- A.
ACE inhibitors
- B.
ARBs
- C.
Diuretics
- D.
Direct Vasodilators
- 8.Dilation of veins decreases ______, while dilation of arteries decreases _______.
- A.
Preload, afterload
- B.
Afterload, preload
- 9._______ are commonly used venous dilators in CHF.
- A.
Resins
- B.
Nitrates
- C.
Inotropic agents
- D.
Statins
- 10.You have an African American patient who is intolerant to beta blockers. You know that what combination of medications is very effective in black patients?
- 11.______ reduces afterload, while _____ reduces preload.
- A.
Hydralazine, nitrate
- B.
Nitrate, hydralazine
- 12.Avoid ________ in patients with HF.
- 13.All of the following are positive inotropic agents, EXCEPT:
- A.
Beta adrenergic agonists
- B.
Digitalis glycosides
- C.
Beta adrenergic antagonists
- D.
Phosphodiesterase inhibitors
- 14.Which of the following is the only oral inotropic agent available?
- A.
Dobutamine
- B.
Inamrinone
- C.
Digoxin
- D.
Milrinone
- 15.Which of the following are indications to prescribe Digoxin?
- A.
Pts with left ventricular systolic dysfunction
- B.
Pts with diastolic or right-sided HF
- C.
Pts who have HF with a fib
- D.
Pts with mild to moderate HF
- E.
Both A and C
- F.
Both C and D
- 16.All of the following are factors predisposing a pt to digoxin toxicity, EXCEPT:
- A.
Hypokalemia
- B.
Hyperkalemia
- C.
Hypercalcemia
- D.
Hypomagnesemia
- 17.All of the following medications decrease preload, EXCEPT:
- A.
Direct vasodilators
- B.
Diuretics
- C.
Alpha blockers
- D.
ARBs
- 18.This medication prevents sodium retention, myocardial hypertrophy, and hypokalemia and is used in the most advanced cases of HF:
- A.
Epelerenone
- B.
Spironolactone
- C.
Abciximab
- D.
Clopidogrel
- 19.This medication is a competitive antagonist of aldosterone at mineralcortioid receptors and reduces mortality in left ventricular systolic dysfunction and HF after acute MI
- A.
Epelerenone
- B.
Spironolactone
- C.
Melrinone
- D.
Clopidogrel
- 20.All of the following are platelet inhibitors, EXCEPT:
- A.
Aspirin
- B.
Ticlopidine
- C.
Abciximab
- D.
Warfarin
- E.
Eptifibatide
- 21.A pt is in the ER c/o CP. She states that she has severe asthma and is finding it hard to breathe. What can you NOT give this patient?
- A.
Aspirin
- B.
Clopidogrel
- C.
Abciximab
- D.
Warfarin
- 22.This medication has an FDA black warning label for bleeding and stroke
- A.
Ticlopidine
- B.
Clopidogrel
- C.
Aspirin
- D.
Prasugrel
- 23.Neutropenia, thrombotic thrombocytopenic purpura, and aplastic anemia are all side effects of....
- A.
Ticlopidine
- B.
Warfarin
- C.
Heparin
- D.
Lovastatin
- 24.Hx of stroke, brain tumor, metastatic cancer, head trauma or intracranial bleeding, or pts with healing wounds may not be administered what medication?
- A.
HMG CoA Reductase inhibitors
- B.
Beta Blockers
- C.
Thrombolytic agents
- D.
Aspirin
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