Test Your Life Science Knowledge!

1. For adherent cells, adhesion provides a signal for cells to do which of the following?

Grow and divide

Transduce differentiation signals

Enhance survival

All of the above

Cell adhesion is the process cells interact and attach to a surface, substrate or another cell, mediated by interactions between molecules of the cell surface.

Explanation

Cell adhesion is the process cells interact and attach to a surface, substrate or another cell, mediated by interactions between molecules of the cell surface.

2. TrueORF Gold ORF clones are the only expression validated cDNA clones.

True

False

TrueORF Gold is OriGene’s collection of premium cDNA clones that have passed the ultimate tests: sequence verification and protein expression validation.

Explanation

TrueORF Gold is OriGene’s collection of premium cDNA clones that have passed the ultimate tests: sequence verification and protein expression validation.

3. Cell culture is in vitro because (choose the best answer)?

Cells are not touching each other

Interactions with other cell types and 3D interactions are lost

Cells have lost some proteins

Changes occur in the cell membrane

in vitro studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

Explanation

in vitro studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

4. Lentiviruses are a subclass of which virus strain?

Retroviruses

Adenoviruses

Adeno-associated Viruses

Herpes Viruses

Lentivirus is a genus of viruses of the Retroviridae family, characterized by a long incubation period.

Explanation

Lentivirus is a genus of viruses of the Retroviridae family, characterized by a long incubation period.

5. What does "CRISPR" stand for?

Clustered Regularly Interdependent Short Palindromic Repeats

Clustered Regularly Interference Short Palindromic Repeats

Clustered Regularly Interspaced Short Palindromic Repeats

Clustered Regularly Interspaced Short Polymer Repeats

CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system which forms the basis for the popular CRISPR-Cas9 genome editing technology.

Explanation

CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system which forms the basis for the popular CRISPR-Cas9 genome editing technology.

6. In what year is OriGene Technologies founded as a research tool company?

1994

1995

1996

1999

2001

OriGene Technologies was founded as a research tool company to focus on the creation of the largest commercial collection of full-length human cDNAs in a standard expression vector.

Explanation

OriGene Technologies was founded as a research tool company to focus on the creation of the largest commercial collection of full-length human cDNAs in a standard expression vector.

7. Which of the following are key features of OriGene's recombinant human proteins? (Select all that apply)

Broadest Coverage

Optimal preservation of protein structure, post-translational modifications and functions

Diverse product formats

Large scale production available

All are key features for OriGene's recombinant human proteins. For details, visit http://www.origene.com/Protein/

Explanation

All are key features for OriGene's recombinant human proteins. For details, visit http://www.origene.com/Protein/

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8. What genes control transgene packaging during lentiviral transduction?

Vif, vpr, and vpu

Env, nef, and pol

Rev, gag, and pol

Lentiviral vectors are derived from HIV. 3rd generation lentiviral systems have reduced the number of HIV genes required for transgene delivery to 3, rev, gag, and pol, improving the biosafety of the system.

Explanation

Lentiviral vectors are derived from HIV. 3rd generation lentiviral systems have reduced the number of HIV genes required for transgene delivery to 3, rev, gag, and pol, improving the biosafety of the system.

9. Which of the following products does OriGene offer? (Check All that apply)

CDNA Clones

CRISPR

Antibodies

Recombinant Human Proteins

Human Cancer and Normal Tissue

ShRNA

OriGene offers all these products!

Explanation

OriGene offers all these products!

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10. What cell types can lentiviral vectors infect? (Check all that apply)

Non-dividing cells only

Actively dividing cells

Quiescent cells

Lentiviruses can infect non-dividing and actively dividing cells. They are one of the most efficient methods of a gene delivery vector. The only cells lentiviruses cannot gain access to are quiescent cells (in the G0 state) because this blocks the reverse transcription step.

Explanation

Lentiviruses can infect non-dividing and actively dividing cells. They are one of the most efficient methods of a gene delivery vector. The only cells lentiviruses cannot gain access to are quiescent cells (in the G0 state) because this blocks the reverse transcription step.

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